body, html {
  /*overflow-y: scroll;*/
  overflow-x: hidden;
}

.page-section-inner {
  max-width: 100%;
}

.laura-safety #adaura-adverse-reactions-one {
  margin-top: 40px;
  margin-bottom: 45px;
}

.laura-safety .primary-navigation .nav.stacked-menu {
  display: none;
}

.laura-safety .primary-navigation .nav>li.list-3 a {
  /*font-weight: 800;*/
  color: #fff;
}

.adverse-container .page-section-inner,.laboratory-section .page-section-inner {
  max-width: 800px;
  margin: 0 auto;
  padding: 0;
  width: 100%;
}

.main-content-container .sectionContainer.section:first-child {
  min-height: initial;
  max-width: 100%;
}

.main-heading {
  max-width: 725px;
  margin-bottom: 20px;
  font-weight: 800;
  font-size: 30px;
  line-height: 36px;
  color: #5B305D;
  display: block;
  margin-top: 20px;
}

#adverse-reaction {
  padding: 30px 0 45px;
}

.border-none {
  border-top: 2px solid #fff !important;
}

table.lab-table {
  margin: 0!important;
  max-width: 720px;
  margin-left: 40px!important;
}

p.tab-title.chart-head {
  margin: 0;
}

p.tab-title.chart-head sup {
  top: -0.4em;
}

.lab-table.one td.chart-body {
  line-height: 20px!important;
  font-weight: 500!important;
  color: #3b3c3e;
}

.customTable th {
  font-size: 17px;
  line-height: 19px!important;
  /* padding: 0 8px 0px; */
  ;
}

.chart-head3 {
  position: relative;
  top: 8px;
  ;
}

.lab-table.one .chart-header-purple, .lab-table.one th.chart-body {
  /*border-left: none;*/
  ;
}

.lab-table.one .chart-header-purple {
  font-weight: 700;
}

.grey-border-none {
  border-bottom: 1px solid rgb(240, 240, 240) !important;
}

.customTable td:nth-child(1) {
  padding-top: 0px !important;
}

.customTable td.ffb-med {
  font-weight: 600 !important;
}

.customTable.two .borderbtm0 td:first-child {
  padding-left: 10px !important;
  font-weight: 600 !important;
  background: #fff;
  border-bottom: 1px solid #fff !important;
}

.customTable.two .bordertop0 td:first-child {
  padding-left: 10px !important;
  font-weight: 500 !important;
}

#adaura-adverse-reactions {
/*background: url('/content/dam/open-digital/tagrisso-hcp/us/en/desktop/Hero-banner.png');*/
/*height: 141px;*/
/*margin-top: 100px;*/
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/inner-bg-v1.jpg) no-repeat;
  height: 141px;
  margin-top: 100px;
  background-size: 125% auto;
  background-position: center;
  transition: 1s ease;
}

.dom-ready #adaura-adverse-reactions {
  background-size: 200% auto;
  transition: 4s ease;
}

ul.bullet-list.dose-red {
  margin: 25px 0;
/*margin-left: 0!important;*/
  ;
}

ul.bullet-list.dose-red li {
  margin-bottom: 18px;
}

ul.bullet-list.dose-red li ul.bullet-list-sublist {
  list-style-type: none;
  padding-left: 12px;
}

ul.bullet-list-sublist li:before {
  content: "\2014";
  margin-left: -3px;
  color: #333333;
}

ul.bullet-list li ul.dose-red-sub-list {
  list-style-type: none;
  padding-left: 11px;
}

.laura-safety ul.bullet-list.dose-red li ul.dose-red-sub-list li:marker,
.laura-safety ul.bullet-list li ul.sub-list li:marker {
  list-style-type: none;
}

.laura-safety ul.bullet-list.dose-red li ul.dose-red-sub-list li:before,
.laura-safety ul.bullet-list li ul.sub-list li:before {
  content: "\2014";
  margin-left: -3px;
  color: #333333;
}

.laura-safety .tab-title {
  margin-top: 25px;
  margin-bottom: 0px;
}

.laboratory-section {
  background-color: #F1F1F1;
  padding: 50px 0 58px;
/*box-shadow: 0px 0px 20px #0000004D;*/
  ;
}

.lab-table.two tr:nth-child(1) td:nth-child(1) {
  border: 0;
}

.laboratory-section .main-heading {
  max-width: 800px;
  margin-bottom: 30px;
  margin-top: 15px;
}

table.lab-table.two {
/*margin-top: 20px!important;*/
  margin-bottom: 38px!important;
}

.customTable.two td {
  padding: 1px !important;
}

.laboratory-section .table-btm-text ul.bullet-list.dose-red {
  margin: 20px 0 20px 7px!important;
}

.laboratory-section .table-btm-text ul.bullet-list.dose-red li {
  margin-bottom: 0;
  padding-bottom: 15px;
}

.laboratory-section .table-btm-text ul.bullet-list.dose-red.second-list li {
  margin-bottom: 15px;
}

.table-btm-text>ul {
/* margin-left: 5px!important; */
  ;
}

ul.sub-list li::marker {
  content: '';
}

ul.sub-list li:before {
  content: "a";
  position: absolute;
  left: -15px;
}

ul.sub-list {
  padding-left: 17px;
}

.table-btm-text .footnote {
  margin: 5px 0 0 0;
  font-size: 12px;
  line-height: 16px!important;
  font-family: "Barlow";
  text-indent: -5px;
}

.laura-safety ul.bullet-list li:before {
  content: '\2022';
  color: #009398;
  position: absolute;
  left: -8px;
  /*font-size: 18px;*/
  top: -1px;
}

.laura-safety .adverse-footenote {
  margin-top: -12px;
}

.laura-safety .adverse-footenote .footnotes {
  padding-left: 0px;
}

.radiation-block {
  margin-top: 55px;
}

.radiation-block ul.bullet-list.dose-red {
    /*margin: 20px 0 20px 9px!important;*/
  margin: 20px 0 20px 8px !important;
}

.radiation-block img.chart {
  margin: 23px 0 10px 30px;
}

ul.bullet-list.dose-red li {
  padding-bottom: 0;
}

.radiation-block .chart+ul.bullet-list.dose-red {
  margin-bottom: 25px!important;
}

.radiation-block .tab-title {
  font-size: 15px;
  line-height: 19px!important;
  margin-bottom: 0px;
}

.radiation-block .grey-box ul.bullet-list.dose-red {
  margin: 0!important;
}

.radiation-block .grey-box ul li {
  margin-bottom: 0;
  font-size: 15px;
  line-height: 17px!important;
  font-weight: 700;
  color: #555555;
}

.radiation-block .grey-box ul li:first-child {
  margin-bottom: 6px;
}

.radiation-block .grey-box {
  background-color: #E0E1E3;
  border: 1px solid #707070;
  border-radius: 10px;
  max-width: 595px;
  height: 80px;
  display: flex;
  justify-content: center;
  align-items: center;
  margin: 18px auto 70px;
}

.radiation-block .primary-btn-wrap .primary-button {
  margin-bottom: 0;
}

.laura-safety .visit-btn {
  width: 504px;
  margin: 40px auto 0;
}

.laura-safety .primary-button {
  padding: 8px 50px 7px 50px;
}

.safety-side-effects #laboratory-abnormalities .table-btm-text .footnote {
  margin-top: 0px;
  margin-left: 5px !important;
  text-indent: -4px;
}

.safety-side-effects .laboratory-section .table-btm-text ul.bullet-list.dose-red:nth-child(1) {
  margin: 20px 0 10px 7px !important;
}

.safety-side-effects .laboratory-section .table-btm-text ul.bullet-list.dose-red:nth-child(3) {
  margin: 20px 0 10px 7px !important;
}

.safety-side-effects .laboratory-section .table-btm-text ul.bullet-list.dose-red:nth-child(3) li:nth-child(1) ul.dose-red-sub-list {
  padding-bottom: 15px;
}

.safety-side-effects .laboratory-section .table-btm-text ul.bullet-list.dose-red:nth-child(3) li:nth-child(1) {
  padding-bottom: 0px;
}

.safety-side-effects sup {
  font-family: 'Barlow', sans-serif;
  font-size: 65%;
}


/*28-04-25 Start*/

ul.lab-abn {
  padding-left: 17px;
}

ul.lab-abn li {
  list-style-type: none;
  margin-bottom: 0px !important;
}

ul.lab-abn li:last-child {
  margin-bottom: 18px !important;
}

ul.lab-abn li:before {
  margin-left: -0.36em;
  top: 0px !important;
  color: #333 !important;
  display: inline-block;
  content: "\2014" !important;
  width: 1em;
  left: -8px !important;
}




/*28-04-25 End*/

@media only screen and (max-width: 991px) {
  .laura-nsclc .section-heading-mobile {
        /*min-height: 36px;*/
    ;
  }

  .main-heading {
    font-size: 24px;
    line-height: 30px;
  }

  .ild-section {
    padding: 50px 0 0;
  }

  #ild-section {
    z-index: 1;
  }

  .page-section-inner {
    padding: 0;
  }

  .adverse-container .page-section-inner,.laboratory-section .page-section-inner {
    padding: 0 20px;
  }

/*@keyframes scale-up {*/
/*       from {*/
/*           transform: scale(1.0);*/
/*       }*/
/*       to {*/
/*           transform: scale(1.5);*/
/*       }*/
/*   }*/

/*.safety-side-effects #banner {*/
    /*background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/Hero-banner-mobile.png) no-repeat;*/
/*       background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/inner-bg-v1.jpg) no-repeat;*/
/*       margin-top: 12px;*/
/*       margin-top: 66px;*/
/*       padding-top: 13px;*/
      /*height: 110px;*/
      /*height: 132px;*/
/*       background-size: cover;*/
/*       background-position: top;*/
      /*margin-top: 66px;*/
      /*padding-top: 13px;*/
      /*height: 110px;*/
      /*content: "";*/
      /*background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/inner-bg-v1.jpg) no-repeat;*/
      /*background-position: center 25%;*/
      /*background-size: cover;*/
      /*width: 100%;*/
      /*left: 0;*/
      /*top: 0;*/
      /*transition: all 1s ease-in;*/
      /*-webkit-transition: all 1s ease-in;*/
      /*transform : none;*/
      /*animation: 1s linear forwards scale-up;*/
      /*transition: 1s ease;*/
/*}*/

 /*.dom-ready #banner:after {*/
/*      animation: 1s linear forwards scale-up;*/
/*  }*/
  /*.dom-ready #banner {*/
      /*background-position: center; */
      /*background-size: cover;*/
     
      /*transform: scale(1.5);*/
      
      /*background-position-y: center !important;*/
      /* background-size: 500%;*/
      
      /*transform: scale(1.8);*/
  /*    background-size: 450%;*/
  /*     transition: 1s ease;*/
      /*background-position-y: -2px;*/
  /*}*/
  
  
  /*@keyframes scale-upm {*/
  /*      from {*/
  /*        background-size: 125% auto;*/
          /*background-position-y: -14px;*/
  /*      }*/
  /*      to {*/
  /*        background-size: 400% auto;*/
          /*transform: scale(2);*/
          /*background-position-y: -24px;*/
  /*      }*/
  /*    }*/

  /*.dom-ready #banner {*/
  /*    animation: 2.5s linear forwards scale-upm;*/
  /*    background-position-y: -26px;*/
  /*}*/
  
  .safety-side-effects #adaura-adverse-reactions {
    background-size: cover;
    height: 90px;
  }
  
  /*@keyframes scale-upm {*/
  /*      from {*/
  /*        background-size: 200%;*/
          /*background-position-y: -14px;*/
  /*      }*/
  /*      to {*/
  /*        background-size: 500% auto;*/
          /*transform: scale(2);*/
          /*background-position-y: -14px;*/
          /*background-position-y: -40px;*/
  /*      }*/
  /*    }*/
  
  @  keyframes scale-upm {
    from {
  transform: scale(1);
  }

  to {
    transform: scale(2);
  }
}

.dom-ready #adaura-adverse-reactions {
        /*animation: 2.5s linear forwards scale-upm;*/
        /* height: 120px; */
  background-position-y: 3px !important;
        /* background-size: cover; */
        /* transform: scale(2); */
  transform: scale(1.5);
  margin-top: 134px;
  margin-top: 50px;
  height: 132px;
}

.laura-safety #adaura-adverse-reactions-one {
  margin-top: 7px;
  margin-bottom: 45px;
}

#adverse-reaction {
  padding: 0px 0 27px;
}

#adverse-reaction  .main-heading {
  margin: 12px 0 22px 0;
}

tr.span1 th {
  font-size: 15px;
}

tr.span1 th.chart-head3,.customTable tr:nth-child(1) th {
  font-size: 17px;
  line-height: 20px!important;
}

tr.span1 th.chart-head3 {
  top: 0px;
  padding-left: 10px;
}

table.lab-table {
  margin: 5px 0 0 0!important;
}

.customTable td {
  font-size: 15px;
  line-height: 17px;
}

.lab-table.one td.chart-body {
  line-height: 25px!important;
}

.lab-table tr>td,.lab-table tr>th {
  width: 41px;
  padding: 4px 0px;
}

.lab-table.one tr>td:nth-child(1) {
  min-width: 110px;
  padding-left: 10px !important;
  padding-top: 5px !important;
  padding-bottom: 7px !important;
}

.laura-safety .adverse-footenote {
  margin: 40px 0 0 0;
}

.laboratory-section {
  padding: 40px 0 25px;
  z-index: 1;
}

.laboratory-section .main-heading {
  margin: 0 0 35px;
  padding-right: 15px;
}

.customTable.two td {
  line-height: 28px;
}

.table-btm-text .footnote {
  margin: 0px 0 0 0;
  margin-right: -4px;
}

.laboratory-section .radiation-block .main-heading {
  margin: 0 0 30px;
}

.radiation-block .main-heading+ul+p {
  margin: 27px 0 0 0;
}

.radiation-block img.chart {
  margin: 15px auto 30px;
}

.radiation-block img.chart+ul+p {
  /*padding: 0 40px;*/
  padding: 0px 40px 10px;
}

.radiation-block .grey-box {
  margin: 0  20px 50px;
  height: 105px;
  padding: 0px 0px 0 22px;
}

.radiation-block .primary-btn-wrap .primary-button {
  line-height: 20px!important;
  padding: 4px 60px;
}

.laura-safety .visit-btn {
  max-width: 333px;
  width: 100%;
  margin: 30px auto 10px;
}

ul.bullet-list.dose-red {
  margin-bottom: 0px;
  margin-left: 8px !important;
}

.next-line-footnote {
  text-indent: -5px;
  display: block;
}

.radiation-block {
  margin-top: 40px;
}

.laboratory-section .table-btm-text ul.bullet-list.dose-red {
  margin: 20px 0 20px 0px !important;
}

#laboratory-abnormalities > div.page-section-inner > div:nth-child(3) > div > div > ul:nth-child(5) {
  margin-bottom: 38px !important;
}

#adaura-adverse-reactions-one ul.bullet-list.dose-red.first-list {
  margin-left: 8px !important;
}

.safety-side-effects #laboratory-abnormalities ul.bullet-list.dose-red {
  margin-left: 4px !important;
}

.safety-side-effects .adverse-table-wrap.laura-rad-oncologists .customTable tr:nth-child(1) th {
  padding-bottom: 2px !important;
}

.safety-side-effects #laboratory-abnormalities .customTable tr:nth-child(1) th {
  padding-bottom: 9px !important;
}
}

@media only screen and (min-width: 768px) and (max-width: 1024px) {
  table.lab-table {
    max-width: 100%;
  }
}

@media screen and (min-width: 320px) and (max-width: 373px) {
  table.lab-table.two {
    margin-left: -13px !important;
  }

  .lab-table tr>td, .lab-table tr>th {
    padding: 4px 1px;
  }

  .lab-table tr.span1 th:first-child {
    font-size: 15px;
  }

  .lab-table tr.span1 th:not(:first-child) {
    font-size: 14px;
  }
}

@media screen and (min-width: 1600px) {
  .dom-ready #adaura-adverse-reactions {
    background-size: 100% auto;
    transition: 2s ease;
  }
}

.text.parbase.section .adverse-footenote {
  margin-left: 7px !important;
}

.ild-section {
  padding: 50px 0 58px;
}

.ild-section .page-section-inner {
  max-width: 800px;
  margin: 0 auto;
  padding: 0 20px;
  width: 100%;
}

.ild-section .ild-table th:first-child {
  width: 300px;
}

.ild-section .ild-table th:not(:first-child) {
  width: 120px;
  padding: 8px 11px;
}

.ild-section .ild-tablehead {
  text-align: center;
  max-width: 420px;
  margin: 40px auto 20px;
}

.ild-section .ild-table2 td:first-child {
  line-height: 1.2;
  width: 30%;
  padding: 10px 40px 10px 0 !important;
  !i;!;
  /* padding-right: 40px !important; */
  /* padding-bottom: 4px !important; */;
}

.ild-section .ild-table2 td:not(:first-child) {
  padding: 0px 19px !important;
  background-color: rgb(240,240,240);
}

.ild-section .ild-table2 td {
  text-align: left;
}

@media only screen and (max-width:991px) {
  .ild-section .ild-table2 td:not(:first-child) {
    line-height: 18px;
    padding-top: 2px !important;
    padding-bottom: 2px !important;
  }

  .ild-section .ild-table th:not(:first-child) {
    padding: 0 !important;
  }

  .laura-rad-oncologists ul.bullet-list {
    margin-left: 10px !important;
  }

  .ild-section {
    padding: 50px 0 0;
  }
}

@media only screen and (max-width:400px) {
  .laura-safety .eyebrow {
    max-width: 341px;
  }
}

/*30-04-25*/
@media only screen and (max-width:991px) {
    
  .laura-safety .copy-right.footnotes {
    max-width: 180px;
    margin: 5px auto;
  }
     .laura-safety .footer-content {
        padding: 0 79px;
    }
  .laura-safety .eyebrow {
    margin: 20px 0px 10px;
  }

  td.chart-body.ffb-med.ln-hei {
    line-height: 20px !important;
  }
}

@media only screen and (min-width:992px) {
  .laura-safety .footnotes.first {
    text-indent: -6px;
    margin-left: 5px;
  }

  .laura-safety .footnotes.second {
    text-indent: -6px;
    margin-left: 6px;
  }

  .laura-safety .footnotes.third {
    text-indent: -6px;
    margin-left: 5px;
  }

  .laura-safety .footnotes.forth {
    text-indent: -4px;
    margin-left: 4px;
  }

  .laura-safety .footnotes.singleline.fifth {
    text-indent: -5px;
    margin-left: 6px;
  }

  .laura-safety .footnotes.six {
    text-indent: -5px;
    margin-left: 4px;
  }

  .laura-safety .footnotes.seven {
    text-indent: -5px;
    margin-left: 3px;
  }

  .laura-safety .footnotes.eight {
    text-indent: -8px;
    margin-left: 2px;
  }

  .laura-safety .footnotes.nine {
    text-indent: -6px;
    margin-left: 3px;
  }

  .laura-safety .footnotes.ten {
    text-indent: -10px;
    margin-left: 5px;
  }

  .laura-safety .footnotes.eleven {
    text-indent: -7px;
    margin-left: 3px;
  }
}