/* Resesctable Efficacy page styling*/
.efficacy {
  /*background:url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/eff-des.jpg) no-repeat;*/
  /*background-size:1366px 2271px;*/
  /*width:1366px;*/
  /*height:2271px;*/;
}
.efficacy.resectable-nsclc .footnotes.align

 {
    margin: 0;
    text-indent: -4px;
}
.efficacy.resectable-nsclc .footnotes.align:nth-last-child(1)

 {
   
    text-indent: -9px;
}


.slide-frm-right {
  transform: translate(19em);
}

.bar-chart-horizontal sup {
  font-size: 60%;
}

.az-panel-title.panel-title {
  /*pointer-events: none;*/;
}

.ml-2 {
  left: 2px;
}

.surgeon .font-b {
  font-weight: bold;
}

.efficacy .d-img-1 {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/New-Callout-Desktop.png) no-repeat;
  background-size: 100% 100%;
  width: 107px;
  height: 54px;
    /* position: relative; */
    /* left: -57px; */
    /* z-index: 99; */
    /* height: 55px; */
    /* position: relative; */
    /* top: 23px; */
    /* right: 56px; */
  z-index: 99;
  height: 54px;
  position: relative;
  top: 28px;
  right: 57px;
  left: -64px;
  display: none;
}
/*.efficacy .d-img-1::before{
       color: #FF00BA !important;
    content: "[";
    position: relative;
    font-size: 54px;
    left: -47px;
    top: 13px;
    font-family: system-ui !important;
    font-weight: 100 !important;
}
.efficacy .d-img-1::after{
        color: #FF00BA !important;
    content: "]";
    position: relative;
    font-size: 54px;
    right: -48px;
    top: 2px;
    font-family: system-ui !important;
    font-weight: 100 !important;
}*/
/*.efficacy .d-fl img::after{*/
/*        color: #F527FF !important;*/
/*    content: "]";*/
/*    position: relative;*/
/*    font-size: 72px;*/
/*    right: -80px;*/
/*    top: 12px;*/
/*    font-family: system-ui !important;*/
/*    font-weight: 100 !important;*/
/*}*/
#subgroups .az-panel-title.panel-title {
  pointer-events: auto;
}

.customTable .borderbtm0 td {
  border-bottom: 0 none;
}

.bordertop0 td {
  border-top: 0 none;
}

p.pill-txt {
  font-size: 10px;
  line-height: 12px;
}

.section-1 .eyebrow {
  margin: 35px 0 0 0;
}

.section-1 h1 {
  margin: 15px 0 27px 0;
}

.section-1 .data-copy ,.section-1 .accordion.section {
  max-width: 705px;
  margin: 0 auto;
}

.section-1 .accordion.section {
  margin: 0 auto 34px !important;
}

.section-1 .subhead {
  margin: 0 0 36px 0;
}

.section-1 .data-copy {
  border-top-left-radius: 20px;
  border-top-right-radius: 20px;
  overflow: hidden;
}

.copy-content {
  margin: 19px 0 15px 13px;
  transform: translate3d(100%, 0, 0);
}

.efficacy .no-display {
  display: none;
}

.copy-per {
  margin: 10px 0 0 0;
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/shape-whitebg.png) no-repeat;
  transform: translate3d(0, -100%, 0);
  max-width: 138px;
  width: 100%;
  min-height: 97px;
  margin: 10px 0 0 40px;
}

.copy-per p {
/*font: normal normal 800 63px/19px Barlow;*/
  padding: 20px 0 20px 9px;
  letter-spacing: -0.38px;
  font: normal normal 700 70px/19px Barlow;
  padding: 15px 0 0 0;
  margin-top: 6px;
}

.cns-progression-vertical-graph li.ruler:first-child p {
  margin-left: -24px;
}

.adaura-box {
  padding: 10px 56px 0 15px;
}

.efficacy .left-title, .efficacy .right-title {
  font-size: 15px;
  line-height: 19px!important;
  font-weight: 600;
  text-align: center;
}

.efficacy .sm-box-1, .efficacy .sm-box-2 {
  background: none;
}

.efficacy .sm-box-1 .ffb-sb, .efficacy .sm-box-2 .ffb-sb {
  padding-left: 8px;
}

.efficacy .sm-box-1 .ffb-sb li, .efficacy .sm-box-2 .ffb-sb li {
  font-size: 16px;
  line-height: 20px!important;
  color: #1A1818;
}
/*.copy-content-lg {*/
/*    font-size: 28px !important;*/
/*    line-height: 27px !important;*/
/*}*/
.demographic-table .purple-txt {
  color: #5B305D;
}

.copy-content-med {
  font-size: 23px;
/*line-height: 27px;*/
  line-height: 22px;
}

.sm-content,.copy-content-med,.vs-txt {
  color: #333333;
}

.copy-content-sm {
  font-size: 14px;
/*line-height: 27px;*/
  line-height: 24px;
}

.is-visible .copy-per, .is-visible .copy-content {
  transform: translate3d(0, 0, 0);
  transition: all 1.5s ease;
}

.section-1 .bullet-list,.section-15 .nccn-footnotes {
  width: 85%;
  margin: 0 auto !important;
}
.section-1 .bullet-list li:before{
  left: -2px;
}
.nccn-content {
  font-size: 16px;
  line-height: 20px !important;
  max-width: 541px;
}

#egfrm-bullet-fix {
  margin-bottom: -32px;
  margin-top: -37px;
}

#meta-eff-nccn-banner-fix-1 {
  width: 162px;
  position: relative;
  left: 5px;
}

.section-1 .nccn-block {
  margin: 25px 0 0 0;
}

.resectable-nsclc .copy-per p {
  font: normal normal 700 70px/19px Barlow;
  padding: 7px 0 0 0;
}

.section-2 .data-copy,.metastatic-nsclc .section-6 .data-copy {
  max-width: 707px;
  border-top-left-radius: 20px;
  border-top-right-radius: 20px;
  margin: 0 auto;
/*border: 2px solid #9B9B9B;*/
  padding: 7px 0 8px 0;
}

.metastatic-nsclc .section-6 .data-copy {
  padding-top: 0;
}

.metastatic-nsclc .section-2 .data-copy, .metastatic-nsclc .section-6 .data-copy {
  border: 2px solid #9B9B9B;
  border-bottom: 0;
}

.metastatic-nsclc .section-9 .visit-btn a {
  padding: 9px 0;
}

.cns-progression-vertical-graph .bar-graph1-copy .purple-txt, .cns-progression-vertical-graph .bar-graph2-copy .purple-txt {
  text-align: center;
}

.top-content {
  text-align: center;
}

.metastatic-nsclc .section-1  .panel-body img {
  padding: 30px 10px 10px 10px;
}

.section-2 .green-banner {
  margin: 40px 0 40px 0;
}

.section-2 .green-banner p {
  padding: 15px 0 15px 0;
}

.section-3 .last-footnote {
  margin: 0 0 0 0;
}

.section-4 .eyebrow {
  margin: 55px 0 10px 0;
}

.section-4 h1 {
  margin: 0;
}

.efficacy.resectable-nsclc .text-4-1 sup {
  top: -0.47em;
}

.section-4 .subhead {
/*margin: 20px 0 38px 0;*/
  margin: 30px 0px 25px 0px;
}

.section-4 .subhead2 {
  margin: 45px 0 25px 0;
}

.efficacy .semi-600 {
  font-weight: 600;
}

.efficacy .med-500 {
  font-weight: 500;
}

.section-4  .stage61-chart {
  display: flex;
  justify-content: center;
  align-items: center;
  /* margin-left: -70px; */
}

.stage61-chart .footnotes {
  line-height: 27px !important;
  left: -3px;
  position: relative;
}

.stage61-chart .hr-txt {
  letter-spacing: 0.35px;
}

.section-4 .adj-table {
  margin: 0 auto !important;
  color: #333;
}

.section-4 .adj-table th {
  font-size: 17px;
  line-height: 22px;
  padding: 5px 43px;
  border-bottom: 4px solid #58305D;
}

.efficacy .refer-section.no-display {
  display: none;
}

.efficacy ul.median-list-5 li {
  font-size: 15px;
  line-height: 16px;
}

.efficacy #cns:before {
  /*box-shadow:0px 0 10px rgb(0 0 0 / 80%)!important;*/;
}

.section-4 .rt-br {
  border-right: 1px solid;
}

.efficacy .no-bs:before, .efficacy .no-bs:after {
  box-shadow: none!important;
}

.efficacy .bs-title {
  font-size: 15px;
  line-height: 19px!important;
  margin-left: 63px;
  padding-top: 50px;
  margin-bottom: 20px;
}

#eff-mobile-chart-brain-title {
  font-weight: 600;
}

table#eff-table-height-fix-a {
  margin-bottom: 40px !important;
}

.efficacy .pb-60 {
  padding-bottom: 60px;
}

.section-4 .adj-table td {
  font-size: 16px;
  line-height: 33px;
  padding: 6px !important;
}

.section-4 .adj-table th:first-child {
  width: 238px;
  padding: 5px 5px 5px 25px;
}

.section-4 .adj-table .left-txt {
  text-align: left;
  padding: 5px 5px 5px 25px !important;
}

.section-4 .adj-table .left-txt {
  width: auto !important;
  border-bottom: none;
  font-size: 16px;
  line-height: 33px;
}

.section-4 .adj-table .last-data {
  border-bottom: 4px solid #58305D;
}

.section-4 .subhead3 {
  margin: 52px 0 20px 0;
}

.section-4 .stage-61-text {
  margin: 25px 0 0 0;
}

.section-4 .stage-61-text.copy-content-lg {
  font-size: 28px;
  line-height: 27px;
}

.section-4 .stage-61-text .txt-md {
  font-size: 23px;
}

.section-4  .stage-61-text .copy-content-sm {
  color: #333333;
}

.section-4 .new-image.table-text.graphic-image {
  width: 664px;
  margin: 0 auto;
}

.efficacy .pink-text.extrabold {
  font-weight: 900!important;
}

.section-5 .green-banner {
  margin: 57px 0 60px 0;
}

.section-5 .green-banner p {
  padding: 4px 0 6px 0;
}

.section-6 .last-footnote {
  margin: 0 0 76px 0;
}

.section-7 .eyebrow {
  margin: 55px 0 0 0;
}

.section-7 h1 {
  margin: 6px 0 0 0;
}

.section-7 .adaura-km-chart {
  margin: 55px 0 0 0;
}

.section-7 .adaura-km-chart .col-md-6.col-sm-12.column-1 {
  max-width: 380px;
}

.section-7 .adaura-km-chart .col-md-6.col-sm-12.column-2 {
  max-width: 384px;
  margin-left: 55px;
}

.section-7 .adaura-km-chart .column-1:after {
  content: "OR";
  position: absolute;
  right: -34px;
  top: 54px;
  color: #5B305A;
  font-family: 'Barlow';
  font-size: 22px;
  bottom: 0;
  margin: 0 auto;
  height: 31px;
  background: #fff;
  text-align: center;
  line-height: 26px;
  width: 31px;
  z-index: 99;
  font-weight: 800;
}

.adaura-km-chart .panel-heading.az-panel-heading {
  padding: 0;
}

.section-7 .adaura-km-chart .column-1:before {
  content: "";
  position: absolute;
  right: -20px;
  top: 5px;
  font-family: 'Barlow';
  width: 2px;
  bottom: 0;
  height: 136px;
  background: #9b9b9b;
  text-align: center;
}

.section-9 .last-footnote {
  margin: 0 0 35px 0;
}

.section-10 .eyebrow {
  margin: 55px 0 20px 0;
}

.section-10 h2 {
  margin: 0 0 42px 0;
}

.section-10 .lg-txt {
  font-size: 48px;
  float: left;
  width: 23%;
  height: 21px;
  padding: 10px 0 0 12px;
}

.efficacy .primary-button {
  padding: 10px 65px 8px 65px;
  width: fit-content;
  margin: auto;
}
.efficacy .primary-button.extra-btn-class {
    padding: 10px 60px 8px 60px;
}

.section-10 .num-lg {
  font-size: 45px;
}

.section-10 .hor-bar p {
  font-size: 18px;
  line-height: 20px !important;
}

.section-10 .hor-bar-one p {
  position: absolute;
  right: -89px;
  top: 25px;
}

.section-10 .hor-bar-two.hor-bar p {
  top: 30px;
  position: absolute;
  right: -96px;
  color: #464749;
}

.hor-line {
  width: 460px;
  border-left: 1px solid #A0A0A0;
  border-bottom: 1px solid #A0A0A0;
  height: 267px;
  left: -45px;
  position: relative;
}

.cns-hor-bar .hor-line {
  left: 0;
}

ul.hor-scale {
  width: 78%;
  height: 14px;
  position: absolute;
  left: 94px;
  bottom: 22px;
}

.hor-ruler {
  border-left: 1px solid #A0A0A0;
  height: 5px;
  width: 16%;
  display: inline-block;
}

.bar-chart-horizontal {
  position: relative;
}

.hor-ruler p {
  position: absolute;
  top: 10px;
  left: -4px;
  font-size: 14px;
  line-height: 8px !important;
}

.hor-bar-container {
  position: relative;
}

.section-10 .hor-bar-container .left-bar-data1,.metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
  position: absolute;
  bottom: 230px;
  left: 42px;
}

.metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
  bottom: 226px;
}

.metastatic-nsclc .hor-bar-one p,.metastatic-nsclc .hor-bar-two.hor-bar p {
  top: 37px;
}

.metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
  bottom: 90px;
}

.metastatic-nsclc .section-9 .visit-btn {
  margin: 55px auto;
}

.metastatic-nsclc .section-1 .nccn-mob-content {
  height: 220px;
}

.section-10 .hor-bar-container .left-bar-data2 {
  position: absolute;
  bottom: 117px;
  font-size: 18px;
  left: 16px;
  color: #464749;
}

.section-10 .hor-line {
  width: 568px;
}

.section-10 ul.hor-scale {
  width: 81%;
  left: 126px;
  padding: 0;
}

.section-10 .hor-ruler {
  width: 12%;
  margin-right: 12px;
}

.section-10 .hor-bar-container .left-bar-data1 {
  position: absolute;
  left: 34px;
}

.section-10 .hor-bar-one {
  position: absolute;
  left: 127px;
  margin: 0 0 28px 0;
  transition: 1s all ease;
}

.section-10 .hor-bar-one,.metastatic-nsclc .section-6 .hor-bar-one {
  position: absolute;
  min-width: 0px;
  height: 92px;
  bottom: 186px;
  left: 134px;
  background: #5B305D;
  margin: 0 0 28px 0;
  transition: 1s all ease;
}

.metastatic-nsclc .section-6 .hor-bar-one {
  left: 135px;
}

.section-10 .is-visible .hor-bar-one.hor-bar {
  min-width: 50px;
}

.section-10 .hor-bar-two,.metastatic-nsclc .section-6 .hor-bar-two {
  position: absolute;
  min-width: 0px;
  height: 92px;
  bottom: 68px;
  left: 134px;
  background: #AEB0B3;
  margin: 0 0 32px 0;
  transition: 1s all ease;
}

.metastatic-nsclc .section-6 .hor-bar-two {
  left: 135px;
}

.section-10 .hor-bar-one,.section-10 .hor-bar-two {
  left: 127px !important;
}

.section-10 .is-visible .hor-bar-two {
  min-width: 475px;
}

img.patients {
  max-width: 568px;
  width: 100%;
}

.efficacy .m-top-zero {
  margin-top: 0!important;
}

.columnControl.section .column-1 .sm-callout {
/*min-height: 139px;*/
  min-height: 90px;
}

.hor-bar p {
  font-size: 12px;
  line-height: 12px !important;
}

.hor-bar-one p {
  position: absolute;
  right: -59px;
  top: 32px;
}

.efficacy.resectable-nsclc .section-1 .copy-content {
  /*margin: 21px 0 20px 11px;*/
     /* margin: 21px 0 20px 11px; */
  margin: 21px 0 22px 11px;
  position: relative;
  top: 8px;
}

.metastatic-nsclc .hor-bar-one p {
  right: -52px;
}

.hor-bar-two.hor-bar p {
  top: 33px;
  position: absolute;
  right: -64px;
  color: #464749;
}

.metastatic-nsclc .hor-bar-two.hor-bar p {
  right: -65px;
}

.section-10 .bullet-list {
  margin: 22px 0 25px 7px;
}

.section-10 .bullet-list li {
  margin-bottom: 15px;
}

.section-10  .brain-section {
  display: flex;
  justify-content: center;
  position: relative;
  margin: 0 11px 65px 0;
}
/*.section-10 .brain-section:after {*/
/*    content: "";*/
/*    background: #5B305D;*/
/*    position: absolute;*/
/*    width: 60%;*/
/*    height: 84%;*/
/*    z-index: -1;*/
/*    border-radius: 15px;*/
/*    top: 11px;*/
/*    left: 22%;*/
/*    transform: skew(-25deg);*/
/*}*/
.section-10  .copy-txt {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/purple-slanted-shape.png);
  background-repeat: no-repeat;
  color: #fff;
  width: 100%;
  max-width: 482px;
  height: 94px;
  padding: 11px 0 0 43px;
  margin: 31px 0 0 -47px;
}

.section-10 .brain-icon-efficacy {
  z-index: 1;
}

.section-10  .img-small-txt {
  display: block;
  font-size: 14px;
  margin: 6px 0 0 12px;
}

.section-10 sup {
  font-size: 60%;
}

.section-10 .last-footnote {
  margin: 0 0 35px 0;
}

.section-11 h2.consistent-dfs {
  margin: 55px 0 42px 0;
}

.section-11 .sect-3 {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/eff-grey-arrow-block-shape.png) no-repeat;
  max-width: 234px;
  height: 138px;
  margin: 0 auto;
  padding: 10px 10px 10px 10px;
}

.section-11 .icons {
  display: flex;
  margin: 10px 0px 10px 0;
}

.section-11 .sect-3 p {
  font-size: 10px;
  line-height: 12px !important;
  margin: 0 0 0 10px;
  text-align: left;
}

.section-11 .adaura-chart-header {
  max-width: 242px;
  font-size: 12px;
  line-height: 16px !important;
  margin: 5px 0 -20px 142px;
  position: relative;
  display: none;
}

.section-11 .sect-3 b {
  font-size: 12.5px;
  line-height: 14px !important;
  margin: 0;
}

.section-11 .panel-body {
  padding: 20px;
}

.section-11 .sect-6 {
  display: flex;
  justify-content: center;
    gap: 100px;
}

.section-11 .sect-7 {
  max-width: 211px;
  height: 118px;
  padding: 12px;
  margin: 10px auto 0;
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/purple-block-shape.png)no-repeat;
}

.section-11 .sect-7 p {
  color: #fff;
  font-size: 15px;
  line-height: 22px !important;
  text-align: center;
  margin: 0;
}

.section-11 .sect-7 li {
  color: #fff;
  font-size: 12px;
  line-height: 14px !important;
  text-align: left;
}

.section-11 .sect-7 span {
  font-size: 22px;
  line-height: 22px;
}

.section-11 .subhead {
  margin: 32px 0 27px 0;
}

.section-11 .accordion.section .accordion-container .panel-default>.panel-heading+.panel-collapse>.panel-body span {
  color: #333;
}
.nowrapmr{
  white-space:nowrap;
  margin-right:-10px;
}
.section-12 .green-banner {
  margin: 40px 0 40px 0;
}

.section-13 .nccn-block {
  margin: 30px auto;
  max-width: 708px;
}

.section-13 .bullet-list {
  margin: 0 0 35px 7px;
}

.section-13 h2.consistent-dfs {
  margin: 60px 0 0 0;
}

.section-13 table.demographic-table {
  max-width: 736px;
  margin: 0 auto !important;
  width: 95%;
}

.section-13 .eff-demographic-chart .panel-body, .section-14 .eff-demographic-chart .panel-body {
  padding: 15px 0 30px 0;
}
/*.section-13 td {*/
/*    padding: 10px 50px 10px 50px !important;*/
/*}*/
.demographic-table th {
  font-size: 17px;
  line-height: 19px;
  color: #333;
}

table.demographic-table tr td:first-child, table.demographic-table tr th:first-child {
  padding-left: 15px !important;
  text-align: left;
}

table.demographic-table tr:nth-child(3) td:first-child, 
table.demographic-table tr:nth-child(4) td:first-child, 
table.demographic-table tr:nth-child(5) td:first-child,table.demographic-table tr:nth-child(7) td:first-child {
  padding-left: 40px !important;
}

.section-13 td {
  padding: 10px 15px 10px 15px !important;
}

.section-13 .chart-body {
  text-align: center;
  padding: 10px 15px !important;
}

.chart-body-copy {
  font-size: 16px;
  padding: 0 65px 0 65px !important;
}

.section-13 th {
  padding: 10px 20px 4px 20px !important;
}

.section-13 td {
  border-bottom: 1px solid;
  border-left: 1px solid;
}

.section-13 td:nth-child(1) {
  border-left: none;
}

.section-13 .chart-body-copy {
  padding: 10px 0 10px 0!important;
  text-align: center;
}

.section-13 .chart-footnote {
  margin: 0 0 40px 56px;
  text-indent: 0;
}

.section-14  tr td:nth-child(1) {
  background: #f1f1f1;
}

p#eff-teal-banner-c {
  font-weight: 600 !important;
}

.callout.adaura-callout .green-banner p {
  padding: 10px 0 10px 0;
  font-weight: 600 !important;
}

.adaura-callout .green-banner {
  margin: 30px 0 65px 0;
}

.section-14 h2.consistent-dfs {
  margin: 55px 0 30px 0;
}

.section-14 .subhead {
  margin: 0 0 30px 0;
}

.section-14 .last-footnote {
  margin: 0 0 65px 0;
}

.section-14 .adaura-staging-table {
  max-width: 660px;
  margin: 0 auto  !important;
}

.section-14 .accordion.section .accordion-container .az-panel-title p {
  line-height: 19px !important;
}

.section-14 tr {
  text-align: left;
}

.section-14 th {
  text-align: center;
  padding: 0 25px 8px 37px;
  font-size: 16px;
  line-height: 17px;
}

.section-14 td {
  border: 1px solid;
  border-left: none;
  color: #333333;
  font-size: 16px;
  padding: 8px !important;
  line-height: 18px !important;
}

.section-14 td:nth-child(3) {
  border-right: none;
}

.adaura-callout .green-banner {
  margin: 30px 0 35px 0;
}

.section-15 h2.consistent-dfs {
  margin: 55px 0 25px 0;
  font-weight: 900;
  max-width: 766px;
}

.section-15 .nccn-block {
  margin: 0 auto;
  /*max-width: 708px;*/
  max-width: 801px !important;
}
.section-15 .nccn-block .polygon {
  min-width:163px;
}

.section-15 .nccn-content {
  font-size: 12.5px;
  line-height: 15px !important;
}

.section-15 .nccn-copy {
  display: block;
  margin-top: 5px;
}

/*.section-15 .nccn-lg.grey-bg:before {*/
/*  height: 125px;*/
/*}*/
.section-15 .nccn-lg.grey-bg:before {
  height: 92px;
}

.section-15 .rtt-box {
  display: flex;
  align-items: flex-start;
  justify-content: space-around;
  max-width: 625px;
  margin: 45px auto;
}

span.icons {
  height: 102px;
  margin-bottom: 20px;
  display: flex;
  flex-direction: row;
  width: 100%;
  align-items: end;
  /* width: 100px; */;
}

span.icons img {
  margin: 0 auto;
  display: block;
}

.efficacy.resectable-nsclc .txt-new {
  font-size: 12px;
  line-height: 15px!important;
  color: #333333;
}

.section-15 .rtt-section {
  width: 30%;
}

.rtt-content .subhead {
  line-height: 20px !important;
}

.section-15 .asco-copy {
  margin: 20px 0 20px 0;
}

.section-15 .last-footnote {
  margin: 0 0 25px 0;
}

.section-15 .visit-btn {
/*max-width: 442px;*/
  max-width: 530px;
  margin: 50px auto 50px auto;
}
/* Metastatic efficacy page styling */
.metastatic-nsclc  .copy-content-med {
  font-size: 18px;
  line-height: 22px;
}

.metastatic-nsclc .section-1 .eyebrow {
  margin: 34px 0 5px 0;
}

.metastatic-nsclc .section-1 h1 {
  margin: 0 0 20px 0;
}

.metastatic-nsclc .section-1 .subhead {
  margin: 0 0 42px 0;
}

.metastatic-nsclc .section-1 .copy-content-med {
  color: #5B305D !important;
}

.metastatic-nsclc .section-2 .copy-per {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/up-arrow-shape.png)no-repeat;
  margin: 0 0 0;
  padding: 0 0 0 0;
  background-size: contain;
  width: 136px;
  min-height: 95px;
  height: 95px;
}

.metastatic-nsclc .section-1 .copy-per {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/whitebg-yr-shape.png) no-repeat;
  width: 20%;
  padding: 0;
}

.metastatic-nsclc .section-1 .hr-txt {
  font-size: 15px;
}

.metastatic-nsclc .section-1 .copy-content {
  margin: 23px 0 0 12px;
}

.metastatic-nsclc .section-1 .num-bold {
  font-size: 45px;
  line-height: 54px;
  letter-spacing: -0.14px;
}

.metastatic-nsclc .section-1 .num-bold sup {
  font-size: 26px;
}

.metastatic-nsclc .section-1 .callout-box {
  display: flex;
  justify-content: center;
  align-items: center;
}

.metastatic-nsclc .section-1 .callout-box p {
  padding: 0 0 0 20px;
  font-size: 17px;
  letter-spacing: -0.8px;
}

.metastatic-nsclc .section-1 .callout-box .vs-txt {
    font-size: 18px;
    line-height: 22px !important;
    letter-spacing: -0.07px;
    padding: 0 0 26px 18px;
    position: relative;
    left: 7px;
    top: 18px;
}

.metastatic-nsclc p.vs-txt::before {
    content: " ";
    position: absolute;
    left: 69%;
    height: 57%;
    border-left: 1px solid #707070;
    top: -25px;
}

.metastatic-nsclc p.vs-txt::after {
    content: " ";
    position: absolute;
    left: 69%;
    height: 57%;
    border-left: 1px solid #707070;
    top: 27px;
}

#meta-ffb-txt-fix-align-1 {
  position: relative;
  left: 4px;
}

.metastatic-nsclc .section-1 .box-center {max-width: 467px;margin: 33px auto 42px;border: 2px solid #5B305D;border-left: none;border-right: none;padding: 20px 0;/* padding-top: 0; */margin-top: 10px;}

.metastatic-nsclc .section-1 .box-center .subhead {
  margin: 5px 0 0 0;
/*margin: 0 0 0 0;*/;
}

.metastatic-nsclc .section-1 .nccn-footnotes {
  width: 75%;
  margin: 0 auto 50px auto;
  margin-left: 80px;
}

.metastatic-nsclc .section-1 .last-footnote {
  font-family: 'Barlow';
  margin: 0 0 54px 0;
  color: #333;
  line-height: 16px !important;
  font-size: 12px;
  left: 1px;
}

.metastatic-nsclc .section-1  .mn-nccn-content {
  background: #f1f1f1;
  padding: 20px 43px 14px 11px;
  height: 90px;
  margin: 0 0 0 12px;
}

    .efficacy.metastatic-nsclc .polygon {
        background: url(/content/dam/open-digital/tagrisso-hcp/us/en/global/nccn-chevron-desktop-1.png) no-repeat;
        background-size: 100% 100%;
        width: 160px;
        height: 90px;
    }

  .efficacy.metastatic-nsclc .polygon p {

    height: 100%;
    text-align: center;
    vertical-align: middle;
    color: #ffffff;
    font-weight: 500;
    padding-right: 4px;
    margin-bottom: 0;
    display: flex;
    justify-content: center;
    align-items: center;
    line-height: normal;
    font-family: 'Barlow';
    font-weight: 600;
    margin-top: 0;
}



.efficacy.metastatic-nsclc .section-1 .nccn-content:before {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/leftcurve-grey.png) no-repeat;
  height: 90px;
}

.metastatic-nsclc .section-1 .nccn-content:before {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/leftcurve-grey.png) no-repeat;
  height: 90px;
}

.m-head {
  font-size: 49px;
}

.m-nccn-sm {
  font-size: 23px;
}
/* 10082 */
.metastatic-nsclc .section-1 h1 {
  margin: 0 0 20px 0;
}

.metastatic-nsclc .section-1 h1.mobile-only {
  letter-spacing: -0.7px;
}

/* 10082 */

.metastatic-nsclc .section-2 .eyebrow {
  margin: 55px 0 0 0;
}

.metastatic-nsclc .section-2 h1 {
  margin: 5px 0 0 0;
}

.metastatic-nsclc .section-2 .subhead {
  margin: 20px 0 40px 0;
}

.metastatic-nsclc .section-2  .copy-content {
  margin: 30px 0 25px 12px;
  width: auto;
}

.metastatic-nsclc .section-2 .lg-num {
  font-size: 69px;
/*padding: 12px 4px 0 0;*/
  padding: 6px 4px 0 0 !important;
}

.metastatic-nsclc .section-2 .copy-content-md {
  font-size: 23px;
  line-height: 27px;
  color: #333333;
}

.metastatic-nsclc .section-2 .txt-med {
  font-size: 19px;
}

.metastatic-nsclc .section-2 .white-bold-txt {
  font-size: 40px;
  color: #fff;
}

.metastatic-nsclc .section-2 .pfs-block-img {
  width: 100%;
  max-width: 126px;
  height: 79px;
  margin: 0 9px 0 0;
  position: relative;
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/purple-bg-shape.png)no-repeat;
}

.metastatic-nsclc .section-2 .pfs-center-block {
  display: flex;
  justify-content: center;
  align-items: center;
}

.metastatic-nsclc .section-2 .pfs-center-block.pfs-block1 {
  margin: 54px auto 0 auto;
}

.metastatic-nsclc .section-2 .pfs-orr {
  position: absolute;
  top: 25px;
  left: 17px;
}

.metastatic-nsclc .section-2 .pfs-median {
  position: absolute;
  left: 20px;
  top: 3px;
}

.metastatic-nsclc .section-2 .pfs-center-block.pfs-block2 {
  margin: 15px 0 50px 53px;
}

.metastatic-nsclc .section-2 .last-footnote {
  margin: 0 0 35px 3px;
}

.metastatic-nsclc .section-3 .eyebrow {
  margin: 55px 0 0 0;
}

.metastatic-nsclc .section-3 .subhead {
  margin: 20px 0 45px 0;
}

.metastatic-nsclc .section-4 .green-banner {
  margin: 40px 0 45px 0;
}

.metastatic-nsclc .section-5 .last-footnote {
  margin: 0 0 35px 0;
  text-indent: 0;
}

.metastatic-nsclc .section-6 h2 {
  margin: 55px 0 20px 0;
}

.metastatic-nsclc .section-6 .subhead1 {
  margin: 0 0 45px 0;
}

.metastatic-nsclc .section-6 .brain-icon {
  position: absolute;
  width: 82px;
  height: auto;
  top: -50px;
  background: #f1f1f1;
  left: 109px;
  z-index: 9;
}

.metastatic-nsclc .section-6 .graphic-subhead {
  background: #f1f1f1;
  left: 24px;
  top: -35px;
  width: 66%;
  padding-left: 66px;
}

.cns-block sup, .copy-per sup {
  font-size: 57%;
}

.metastatic-nsclc .section-6 .graphic-box {
  height: 181px;
  max-width: 714px;
  margin: 90px auto 75px auto;
}

.metastatic-nsclc .section-6 .cns-arrow-section {
  align-items: center;
  display: flex;
  justify-content: space-evenly;
  margin: 80px 0 0 0;
}

.metastatic-nsclc .section-6 .cns-block {
  /*background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/cns-arrow-shape.png);*/
  width: 174px;
  height: 74px;
  position: relative;
}

.metastatic-nsclc .section-6 .cns-block span {
  font-size: 48px;
  line-height: 58px;
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/cns-arrow-shape.png) no-repeat;
  width: 174px;
  height: 74px;
  padding: 3px 46px 9px 22px;
  background-size: 100% 100%;
  left: 0;
  position: relative;
  transition: 1s all ease-out;
}

.metastatic-nsclc .section-6 .cns-block p {
  position: absolute;
  top: -40px;
  left: 40px;
  line-height: 26px !important;
  font-size: 22px;
}

.metastatic-nsclc .section-6 .cns-block1 {
  z-index: 9;
}

.metastatic-nsclc .section-6 .cns-block2 {
  z-index: 8;
}

.metastatic-nsclc .section-6 .cns-block3 {
  z-index: 7;
}

.metastatic-nsclc .section-6 .cns-block2 span {
  left: -168px;
}

.metastatic-nsclc .section-6 .cns-block3 span {
  left: -338px;
}

.metastatic-nsclc .section-6  .copy-content-sm {
  color: #333333;
}

.metastatic-nsclc .section-6 .is-visible .cns-block2 span, .metastatic-nsclc .section-6 .is-visible .cns-block3 span {
  left: 0;
}

.metastatic-nsclc .section-6 .subhead3 {
  margin: 0 0 40px 0;
}

.metastatic-nsclc .section-6 .bullet-list {
  margin: 65px 0 40px 10px;
}
#cns-data > div.page-section-inner.container > div:nth-child(6) > div > ul{
  margin-bottom:10px;
}
.section-9  .verticalSlide  table.customTable {
  margin-top: 0px;
}

.hor-bar span {
  font-size: 41px;
  line-height: 16px;
  /*position: absolute;*/
  /*left: -64px;*/
  /*top: 10px;*/
  ;
}

.hor-bar-container .left-bar-data1 {
  bottom: 240px;
  font-size: 18px;
}

.metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
  bottom: 93px;
  left: -17px;
  font-size: 18px;
}

.metastatic-nsclc .section-6 .last-footnote {
  margin: 0 0 60px 0;
}

.metastatic-nsclc .section-6 .subhead4 {
  margin: 60px 0 55px 0;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph {
  position: relative;
  max-width: 590px;
  margin: 0 auto 25px auto;
}

.metastatic-nsclc .section-6 .bar-chart-horizontal {
  position: relative;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph hr.ver-line {
  height: 375px;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph li:first-child.ruler {
  margin-top: -12px;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph li.ruler {
  height: 75px;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph ul.scale {
  top: 12px;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-one {
  position: absolute;
  width: 91px;
  min-height: 0px;
  bottom: 44px;
  left: 88px;
  background: #936693;
  transition: 1s all ease;
}

.metastatic-nsclc .section-6 .is-visible .bar-one {
  min-height: 228px;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar.small-bar {
  position: absolute;
  top: 0;
  background: #512C51;
  width: 91px;
  min-height: 0px;
  transition: 1s 1s all ease;
  opacity: 0;
  z-index: 0;
}

.metastatic-nsclc .section-6 .is-visible .bar.small-bar {
  min-height: 70px;
  top: -69px;
  opacity: 1;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt {
  position: absolute;
  top: -80px;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar p {
  font-size: 46px;
  line-height: 55px !important;
  margin: 8px 0 -8px;
  text-align: center;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar span {
  font-size: 14px;
  line-height: 16px !important;
}

.hor-txt2 {
  position: absolute;
  bottom: -14px;
  right: 130px;
}

.hor-txt1 {
  position: absolute;
  bottom: -15px;
  left: 97px;
}

.bar-graph1-copy {
  position: absolute;
  top: 86px;
  left: 190px;
}

.bar-graph1-copy span,.bar-graph2-copy span {
  font-size: 45px;
  color: #3B3C3E;
}

.bar-graph1-copy .bottom-content span,.bar-graph2-copy .bottom-content span {
  font-weight: 400 !important;
}

.bar-graph1-copy .purple-txt,.bar-graph2-copy .purple-txt {
  color: #5B305D;
}

.bottom-content {
  margin: 100px 0 0 0;
  text-align: center;
  line-height: 17px !important;
}

.top-content {
  line-height: 17px !important;
}

.bar-graph2-copy {
  position: absolute;
  left: 108px;
  top: 5px;
}

li.ruler:last-child {
  padding-left: 4px;
}

.is-visible .bar-graph2-copy {
  transform: none;
  text-align: center;
}

.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-two.bar-container {
  position: absolute;
  width: 91px;
  right: 150px;
  bottom: 45px;
  min-height: 0px;
  background: #A0A0A0;
  transition: 1s all ease;
}

.metastatic-nsclc .section-6 .is-visible .bar-two.bar-container {
  min-height: 243px;
}

.metastatic-nsclc .section-6  .hor-bar-container .left-bar-data2 {
  position: absolute;
  bottom: 85px;
  left: -18px;
  text-align: right;
  word-spacing: -4px;
}

.metastatic-nsclc .section-6 .hor-line {
  height: 282px;
}

.metastatic-nsclc .section-6 .hor-bar-two.hor-bar {
  min-width: 0px;
  bottom: 42px;
  transition: 1s all ease;
}

.metastatic-nsclc .section-6 .is-visible .hor-bar-two {
  min-width: 345px;
}

.metastatic-nsclc .section-6 .hor-bar-one.hor-bar {
  min-width: 0px;
  bottom: 167px;
  margin-bottom: 40px;
  transition: 1s all ease;
}

.metastatic-nsclc .section-6 .is-visible .hor-bar-one {
  min-width: 143px;
}

.metastatic-nsclc .section-6 .hor-ruler {
  width: 18.75%;
}

.metastatic-nsclc .section-6 .hor-ruler:first-child {
  left: 1px;
}

.metastatic-nsclc .section-7 .green-banner {
  margin: 40px 0 50px 0;
}

.metastatic-nsclc .section-8 .last-footnote {
  margin: 0 0 35px 2px;
}

.metastatic-nsclc .section-9 h2 {
  margin: 55px 0 40px 0;
}

.metastatic-nsclc .section-9 .small-txt {
  margin: 10px 0 30px 0;
}

.double-footnotes {
  text-indent: -5px;
  margin-left: 2px;
  padding-left: 0;
}

.flaura-section {
  display: flex;
  align-items: center;
  margin: 0 auto;
}

.block1 {
  border: 2px solid #0000004D;
  border-radius: 15px;
  width: 100%;
  max-width: 329px;
  padding: 15px 10px 10px 20px;
  margin: 0 40px 0 0;
}

.block1 ul {
  margin: 0 !important;
}

.block1 p,.block1 li {
  font-size: 14px;
  line-height: 16px !important;
}

.block1 .subhead {
  font-size: 16px;
}

.flaura-section .bullet-list {
  padding-left: 8px;
}

.flaura-section .bullet-list li:before {
  color: #3B3C3E;
}

.img1 {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/flaura-purple-shape.png) no-repeat;
  width: 260px;
  height: 70px;
  margin: 0 0 35px 0;
}

.img2 {
  height: 79px;
  padding: 8px 0 0 0;
  width: 262px;
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/flaura-grey-shape.png) no-repeat;
}

.img2 p {
  font-size: 14.5px;
  line-height: 17px !important;
  margin: 0;
}

.img1 p {
  color: #fff;
  margin: 0 !important;
  padding: 15px 0 0 0;
  line-height: 18px !important;
}

p.ratio-lg {
  font-size: 46px;
/*margin-left: 10px;*/
  ;
}

.block2 img {
  display: block;
  margin: 0 20px 30px 30px;
}

img.placebo {
  top: 14px;
  position: relative;
}

.flaura-section li,.heading2 {
  color: #3B3C3E;
}

.metastatic-nsclc .section-9 .accordion.section {
  margin: 50px auto 30px auto;
}

.metastatic-nsclc .section-9 .visit-btn {
  max-width: 500px;
  margin: 50px auto 40px auto;
}

.metastatic-nsclc .section-9 .customTable td:nth-child(1) {
  background: #f1f1f1;
}

div#dfs .panel-body {
  padding: 15px 15px 0px 15px;
}

div#sample-collapse1858997818 p.img {
  margin-bottom: -12px;
}

div#dfs img.desktop-only.az-lazyload.toggle-class {
  margin-top: -25px;
  margin-bottom: -19px;
}

h2.unpre-median,h2.consistent-dfs {
  font-weight: 800;
  font-size: 30px;
  line-height: 36px;
  color: #5B305D;
  margin-top: 5px;
}

.osi-adjuvant {
  width: 544px !important;
}

.n-number {
  font-family: 'Barlow';
  font-weight: 500;
}

.tag-heading-txt {
  font-weight: 700 !important;
}

.efficacy.resectable-nsclc .section-1 h2.new-data {
  color: #5B305D;
}
/* Mobile styling*/
@media screen and (max-width: 991px) {

#section-9 > div.page-section-inner.container{
  padding-right: 48px !important;
}

  #section-5 > div.page-section-inner.container{
      padding-right: 22px !important;
  }
  
    span.n-wr {
    white-space: nowrap;
}
  .section-1 .bullet-list li:before{
  left: 11px;
}
  #rethink-treatment > div.page-section-inner.container > div.columnControl.section > div.multi-column-container > div > div.col-sm-4.col-xs-12.column-2 > div > div > div > p.column-text {
    margin-bottom: 25px;
  }

  #rethink-treatment > div.page-section-inner.container > div.columnControl.section > div.multi-column-container > div > div.col-sm-4.col-xs-12.column-2 > div > div > div > p.column-head.column-head2 {
    margin-top: 20px;
  }

  #rethink-treatment > div.page-section-inner.container > div.columnControl.section > div.multi-column-container > div > div.col-sm-4.col-xs-12.column-1 > div > div > div > p.column-text {
    margin-bottom: 25px;
  }

  .resectable-nsclc.resect-efficacy .multi-column-container {
    margin-top: 15px !important;
  }

  #rethink-treatment > div.page-section-inner.container > div.columnControl.section > div.multi-column-container > div > div.col-sm-4.col-xs-12.column-2 > div > div > div > img {
    padding-left: 14px;
  }

  .columnControl.section .column-1,.columnControl.section .column-2,.columnControl.section .column-3 {
    padding: 0;
  }

  #rethink-treatment > div.page-section-inner.container > div:nth-child(2) > div > div.nccn-block-mob.mobile-only > div {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/2x-nccn-short-white-banner-mobile.png) no-repeat;
    background-position-x: 0px !important;
    background-position-y: 3px !important;
    background-size: contain !important;
  }

  .efficacy #accordion-sec-n-1 .newImage {
    padding-bottom: 0px !important;
  }

  .efficacy .b-le, .efficacy .b-re {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/callout-box-mobile.png) no-repeat!important;
    background-size: 100% 100%!important;
    width: 343px!important;
    height: 247px!important;
  }

  .efficacy .b-le .row-3 .footnote, .efficacy .b-le .row-4 .footnote {
    letter-spacing: 0;
  }

  .efficacy.resectable-nsclc .footnotes.nccn-footnotes.fn_2 {
    text-indent: -6px;
  }

  .efficacy .heading-block .line-3 {
    position: relative;
    margin-left: 0px;
  }

  .efficacy .nccn-bl-footnotes .footnotes {
    margin-left: 34px;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-copy p.purple-txt.extrabold {
    text-align: center;
    font: normal bold 66px/16px Barlow !important;
    letter-spacing: -0.6px;
    color: #5B305D;
  /* padding-top: 19px !important; */
    display: flex;
    height: 100%;
    align-items: center;
    justify-content: center;
    position: relative;
    top: 2px!important;
  }

  .efficacy.resectable-nsclc .section-1 .copy-content {
    margin-left: 0px;
  }
 
 /*.efficacy .heading-block .line-3:before{*/
 /*       color: #FF00BA !important;*/
 /*   content: "[";*/
 /*   position: absolute;*/
 /*   font-size: 42px;*/
 /*   left: 10px;*/
 /*   z-index: 99;*/
 /*   top: 4px;*/
 /*   font-family: system-ui !important;*/
 /*   font-weight: 100 !important;*/
 /*}*/
 /* .efficacy .heading-block .line-3:after{*/
 /*       color: #FF00BA !important;*/
 /*   content: "]";*/
 /*   position: absolute;*/
 /*   font-size: 42px;*/
 /*   right: 12px;*/
 /*   top: 4px;*/
 /*   font-family: system-ui !important;*/
 /*   font-weight: 100 !important;*/
 /* }*/

  .efficacy.resectable-nsclc .section-1 .dfs-copy .num-txt {
    font-size: 61px;
    padding: 8px 0 0 8px;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-copy .x-txt {
    font-size: 35px;
    top: -7px;
    position: relative;
  }

  .efficacy .data-flex-box .data-flex-box-col {
    width: 343px!important;
    max-width: 100%!important;
  }

  .efficacy .user-s-1 {
    padding-left: 22px!important;
    padding-top: 16px!important;
    padding-bottom: 16px!important;
  }

  .efficacy .data-flex-box .data-flex-box-col, .efficacy .section-7 .adaura-km-chart {
    margin: 0 auto;
  }

  .efficacy .data-flex-box {
    margin: 20px -4px 15px!important;
  }

  .efficacy .d-m-img-2 {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/New-img-Mobile.png) no-repeat;
    background-size: 100% 100%;
    width: 87px;
    height: 42px;
    /* position: relative; */
    /* left: -57px; */
    /* z-index: 99; */
    /* height: 55px; */
    /* position: relative; */
    /* top: 23px; */
    /* right: 56px; */
    z-index: 99;
    /* height: 54px; */
    position: relative;
    top: 28px;
    right: 48px;
    display: none;
  }
/*.efficacy .d-m-img-2::before{
        color: #FF00BA !important;
    content: "[";
    position: relative;
    font-size: 50px;
    left: -34px;
    top: 7px;
    font-family: system-ui !important;
    font-weight: 100 !important;
}
.efficacy .d-m-img-2::after{
        color: #FF00BA !important;
    content: "]";
    position: relative;
    font-size: 50px;
    right: -34px;
    top: 2px;
    font-family: system-ui !important;
    font-weight: 100 !important;
}*/
  .efficacy.resectable-nsclc .section-1 h1.new-data {
    font-size: min(8.7vw,36px);
    margin-bottom: 0;
  }

  #cns .final-analysis-link, #subgroups .final-analysis-link {
    padding-top: 25px;
  }

  .efficacy.resectable-nsclc .section-1 h2.egfr-mutation.new-datatwo {
    font-size: min(4.6vw,17.5px);
  }

  .green-banner p.callout.is-visible.ffb-sb {
    padding-bottom: 4px;
  }

/* updates */



  .efficacy.resectable-nsclc .section-13 .patient-img.tab-title img {
    height: 100% !important;
  /*width: 370px !important;*/;
  }

  .is-visible .green-banner {
    transform: revert !important;
  }

  .efficacy .d-fl img.mobile-only {
    left: -47px;
    top: 26px;
    height: 45px;
  }

  #eff-mobile-margin-prior-per {
    position: relative;
    top: 10px;
    padding-top: 15px;
  }

  #eff-mobile-chart-brain-title {
    margin-left: 0;
    text-align: center;
    font-weight: 600;
    margin-top: -40px;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-copy p.purple-txt.extrabold {
    padding-bottom: 30px !important;
  }

  #eff-resec-target-banner-mobile-margin {
    margin-left: 0;
    margin-top: 20px;
  }

  #eff-boxes-fix-stat-copy-fix-b1 {
    position: relative;
    top: 12px;
    font-size: 13px;
    margin-top: 2px !important;
    margin-bottom: 2px !important;
    letter-spacing: -0.42px !important;
  }

  #eff-boxes-fix-stat-copy-fix-b2 {
    position: relative;
    top: 17px;
    line-height: 14px !important;
  }

  #eff-boxes-fixes-dfs-copy-a1 {
    position: relative;
    top: 12px;
    font-size: 13px !important;
    line-height: 15px !important;
  }

  .efficacy .text-6 {
    font-weight: 700 !important;
  }

  p.text-6-1 {
    position: relative;
    top: 2px;
  }

  #eff-boxes-fixes-dfs-copy-a2 {
    padding: 0px 20px;
    position: relative;
    top: 1px;
    max-width: 339px;
  }

  #eff-boxes-fixes-dfs-copy-a3 {
    font-size: 13px !important;
    line-height: 15px !important;
    position: relative;
    top: 6px;
  }

  #eff-boxes-fix-spacer {
    padding: 10px 0px;
    position: relative;
    top: 8px;
    left: 10px;
  }

  p.or-txt:after {
    bottom: 120px !important;
  }

  span#efficacy-mob-brain-copy-fix-a {
    font-weight: 500 !important;
  }

  span#efficacy-mob-brain-copy-fix-b {
    font-weight: 600 !important;
    font-size: 14px;
  }

  span#efficacy-mob-brain-copy-fix-c {
    font-weight: 200 !important;
    font-size: 14px;
  }

  .efficacy.resectable-nsclc .section-10 .brain-section {
    padding-bottom: 20px;
  }

  .efficacy.resectable-nsclc .section-5 .green-banner {
    margin: 25px 0 41px 0 !important;
  }

  .efficacy.resectable-nsclc .section-4 .subhead3 {
    margin: 48px 0 42px 0px !important;
    font-size: 22px;
  }

  #efficacy-graph-title-fix-00 {
    padding: 11px 0 11px 14px;
    text-align: left;
  }

  #graph-efficacy-title-fix-01 {
    display: block;
  }

  .efficacy.resectable-nsclc .section-15 .box-2 .treat-dna-icon {
    width: 96px !important;
    height: auto !important;
    position: relative;
    top: -9px;
  }

  p#eff-margin-rethink-a {
    margin-top: 0px;
  }

  .efficacy ul.median-list-5 {
    margin-bottom: 20px !important;
    padding-top: 20px;
  }

  #eff-extxt-fix {
    position: relative;
    top: -8px;
  }

  #graph-eff-height-a {
    height: 100px;
  }

  #eff-ex-txt-fix-a {
    font-size: 30px;
  }

  #eff-ex-txt-fix-b {
    font-size: 15px;
    font-weight: 600;
  }

  #eff-ex-txt-fix-c {
    font-weight: 400;
  }

  #eff-ex-txt-fix-d {
    font-weight: 400;
    position: relative;
    left: -34px;
    font-size: 15px;
  }

  #graph-eff-height-b {
    max-width: 300px;
  }

/*updates end */

  .metastatic-nsclc .section-6 .bar-chart-horizontal {
    position: relative;
    left: 13px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
    left: 10px;
  }

  .efficacy .heading-block .line-1 {
    font: normal normal 14px/15px Barlow!important;
  }

  .efficacy .heading-block .line-2 {
    font: normal normal 800 28px/23px Barlow!important;
    letter-spacing: -0.5px!important;
  }

  .efficacy .heading-block .line-3 {
    font: normal normal 17px/19px Barlow!important;
    margin-left: 0px!important;
  }

  .efficacy .yellow-box {
    width: 336px!important;
    height: 112px!important;
  /* margin-left: 0; */
    margin: 10px auto!important;
    max-width: 100%!important;
  }

  .efficacy .data-flex-box {
    flex-direction: column!important;
  /* margin: 0 auto; */
    justify-content: center!important;
  }

  .efficacy .data-flex-box .data-flex-box-col {
      /*  width: 332px!important;*/
  /* height: 235px; */;
  }

  .efficacy .data-flex-box .green-text-line-1 {
        /* font: normal normal 800 29px/17px Barlow; */
  /* color: #0E8995; */
    font: normal normal 800 29px/17px Barlow!important;
    color: #0E8995!important;
  }

  .efficacy .data-flex-box .green-text-line-2 {
        /* font: normal normal 500 14px/17px Barlow; */
  /* color: #0E8995; */
  /* margin: 5px 0px; */
    font: normal normal 500 14px/17px Barlow!important;
    color: #0E8995!important;
    margin: 8px 0px 8px 0px!important;
  }

  .efficacy .text-5 {
    padding-top: 0!important;
  }

  .efficacy .b-le .row-2 {
        /* padding-top: 11px; */
    padding-top: 8px!important;
  }

  .efficacy .data-flex-box p {
    margin: 0!important;
  }

  .efficacy .b-le .row-3 {
        /* max-width: 358px; */
  /* margin-left: 18px; */
  /* margin-right: 10px; */
  /* max-width: 349px; */
  /* margin: 0 auto; */
  /* max-width: 358px; */
  /* margin-left: 18px; */
  /* margin-right: 10px; */
    max-width: 349px!important;
    margin: 0 auto!important;
    margin-top: 8px!important;
  }

  .efficacy .b-le .row-3 .footnote, .efficacy .b-le .row-4 .footnote {
        /* font: normal normal normal 12px/16px Barlow; */
    font: normal normal normal 13px/15px Barlow!important;
    color: #606060!important;
    text-align: center!important;
  }

  .efficacy .data-flex-box .data-flex-box-col {
       /* width: 332px!important;*/
  /* height: 235px; */
  /*margin-top: 80px!important;*/
  /* max-width: 100%; */
  /* margin: 0 auto; */;
  }

  .efficacy .d-fl {
    display: flex!important;
    justify-content: center!important;
    margin-bottom: -3px!important;
  }

  .efficacy ul.median-list {
    margin-top: 0px!important;
  }

  .efficacy .brd-btm hr {
    width: 250px!important;
    margin: 30px auto 0px !important;
  }

  .efficacy .data-flex-box .data-flex-box-col:nth-child(2) .above-card-wrap .barlow-bold {
    position: relative!important;
  /* left: -44px; */
    left: -58px!important;
    top: 1px!important;
  }

  .efficacy .above-card-wrap .font-style {
    display: block!important;
    font-weight: 500!important;
    line-height: 17px!important;
    font-size: 14px!important;
    margin-top: 1px!important;
  /* margin-left: -79px; */
    position: relative!important;
    left: -58px!important;
    margin-bottom: 6px!important;
  }

  .efficacy.resectable-nsclc .section-1 .km-curve {
    text-align: center!important;
    position: relative!important;
    max-width: 100%!important;
    height: 260px !important;
    width: auto!important;
  }

  .efficacy.resectable-nsclc .section-4 .new-image.table-text.graphic-image {
    text-align: center!important;
    position: relative!important;
    max-width: 100%!important;
    height: auto!important;
    width: auto!important;
    top: -8px;
  }

  .efficacy .desktop-only-1 {
    display: none;
  }
/* ended */

  .metastatic-nsclc .section-1  .panel-body img {
    padding: 20px 10px 0px 10px;
    position: relative;
  /* bottom: 8px; */;
  }

  #pfs .copy-content {
    margin: 20px 0 0 0!important;
  }

  .metastatic-nsclc .section-6 .data-copy .copy-content.no-tsp {
    margin-top: 0px;
  }
/*#pfs .newImage{*/
/*    bottom:10px;*/
/*}*/
  #egfrm-bullet-fix {
    margin-top: revert;
  }

  .met-eff-img-fix1 {
    margin-bottom: 15px;
  }

/*.section-1 .nccn-block-mob {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/nccn-callout-mob.png) no-repeat center 1px;
}*/

  .section-2 .green-banner p.callout.is-visible.ffb-sb {
    padding-bottom: 15px;
  }

  .metastatic-nsclc .section-2 .lg-num {
    padding-top: 1px;
  }

  .section-2 .copy-per p {
    margin-top: 5px;
  }

  div#staging.section-14 table.adaura-staging-table {
    width: 95%;
  }

  span.diff-block {
    display: block;
    padding-top: 3px;
  }

  img.az-80-pill-bottle {
    padding-bottom: 5px;
  }

  .metastatic-nsclc .section-9 .visit-btn a {
    padding: 9px 0;
    padding-right: 36px;
    padding-left: 21px;
    padding-top: 8px;
  }

  .section-6 p.tab-title.ffb-reg.center-txt {
    font-size: 14px;
    line-height: 18px !important;
  }

  img.placebo {
    padding-bottom: 5px;
  }

  .metastatic-nsclc #os .panel-body img {
    width: auto;
    max-width: 375px;
    margin-left: 0px;
  }

  .metastatic-nsclc .cns-pfs-chart img {
    margin-top: 0px;
  }

  .metastatic-nsclc #subgroups .panel-body img {
    margin-left: 0px;
  }

  .metastatic-nsclc .brain-img-section {
    left: -11px;
    position: relative;
  }

  div#subgroups .panel-body img {
    width: auto !important;
    max-width: 100%;
    margin-left: -3px;
    padding: 0 5px;
  }

  .efficacy.resectable-nsclc.resect-efficacy div#subgroups .panel-body img {
    margin-left: 0;
    padding: 0 15px;
  }

  div#subgroups .panel-body {
    padding: 15px 5px;
  }

  .slide-frm-right {
    transform: none;
  }

  .section-1 .eyebrow {
    margin: 35px 0 0 0;
  }

  p.ratio-lg {
    margin-left: 0px;
    text-align: center;
    margin-bottom: -10px;
  }

  .section-1 h1 {
    margin: 5px 0 20px 0;
  }

  .copy-per {
    margin: 12px 0 0 0;
    max-width: 115px;
    height: 80px;
    background-size: contain;
    padding: 0;
    min-height: 80px;
  }

  .section-6 .copy-per {
    padding-top: 5px;
  }

  .section-1 .subhead {
    margin: 0 0 25px 0;
  }

  .is-visible .copy-per, .is-visible .copy-content {
    transform: none;
    transition: none;
  }

  .copy-content {
    margin: 0px;
  }

  .copy-content-lg {
    font-size: 28px;
    line-height: 28px;
  }

  .accordion.section .accordion-container .az-panel-title p {
    padding: 12px 24px 12px 15px;
  }

  .accordion-container .collapse-panel-heading .fa {
    right: 10px;
    top: 14px;
  }

  .nccn-content-mob {
    font-size: 16px;
    line-height: 20px !important;
  }

  .section-1 .bullet-list {
    width: 100%;
    margin: 0 20px;
  }

  .section-1 .nccn-content-mob {
    background-color: #f1f1f1;
    padding: 15px 16px 20px;
  }

  .section-1  .accordion-container .collapse-panel-heading .fa {
    top: 20px;
  }

  .section-4 .adj-table th {
    padding: 5px 8px;
  }

  .section-4 .adj-table td {
    padding: 5px;
  }

  .section-2 .green-banner {
    margin: 20px 0 20px 0;
    width: 85%;
    padding: 0px 0px 0px 38px;
  }

  .section-4 .eyebrow {
    margin: 55px 0 20px 0;
  }

  .section-4 .subhead {
    margin: 20px 0 28px 0;
  }

  .section-4 .subhead2 {
    margin: 49px 0 22px 0;
  }

  .section-4 .accordion.section .accordion-container .az-panel-title p {
    padding: 8px 38px 8px 15px;
  }

  .section-4 .adj-table {
    margin: 15px auto 40px auto !important;
  }

  .stage61-chart p.footnotes.purple-txt.ffb-sb.txt-ctr {
    text-indent: 0px;
    left: 0px;
  }

  .percentage-bar-text {
    margin-top: -20px;
    font-size: 11px;
  }

  .section-10 .bullet-list {
    margin-top: 15px;
  }

  .section-4 .stage61-chart {
    flex-direction: column;
  }

  .section-4 .stage-61-text {
    margin: 5px 10px 0 0;
    transform: none;
    text-align: center;
    margin-left: unset !important;
  }

  .section-4 .new-image.table-text.graphic-image {
    width: inherit;
    margin: 0px;
  }

  .section-5 .green-banner {
    margin: 28px 0 25px 0;
    width: 82%;
    padding: 12px 0px 12px 38px;
  }

  .section-6 .last-footnote {
    margin: 0 0 35px 0;
  }

  p.or-txt {
    text-align: center;
    color: #5B305A;
    font-family: 'Barlow';
    font-size: 22px;
    font-weight: 800;
    width: 45px;
    margin: 10px auto;
    background: #fff;
    z-index: 1;
  }

  p.or-txt:after {
    content: "";
    position: absolute;
    width: 94%;
    height: 2px;
    background: #9b9b9b;
    left: 9px;
    bottom: 9px;
    z-index: -1;
  }

  .efficacy.resectable-nsclc .section-7 .adaura-km-chart p.or-txt {
    background: #f1f1f1;
  }

  .metastatic-nsclc .section-2 .copy-content-md {
    margin-bottom: 2px !important;
    display: inline-block;
  }

  .section-7 .adaura-km-chart .column-1:after,.section-7 .adaura-km-chart .column-1:before {
    display: none;
  }

  .adaura-box {
    padding: 10px 45px 10px 12px;
  }

  .column-1 .adaura-box {
    padding-bottom: 10px;
  }

  .adaura-sm {
    font-size: 12px;
    line-height: 8px !important;
    padding: 0 0 10px 12px;
  }

  .adaura-copy {
    padding-right: 15px;
  }

  .section-7 .eyebrow {
    margin: 55px 0 0 0;
  }

  .section-7 .adaura-km-chart {
    max-width: 376px;
    margin: 35px auto 0 auto;
  }

  .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-2 {
    margin-left: 0;
    padding-right: 0;
  }

  .section-7 .columnControl.section .column-2 {
    padding-left: 0;
  }

  .section-7 .columnControl.section .column-1 {
    padding-right: 0;
  }

  .section-10 .eyebrow {
    margin: 55px 0 20px 0;
  }

  .section-10 h1 {
    margin: 0 0 26px 0;
  }

  .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data1,
.resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data2 {
    font-size: 11px;
    line-height: 14px !important;
  }

  .resectable-nsclc .section-10  .hor-line {
    width: 258px;
    height: 267px;
  }

  .resectable-nsclc .section-10 .hor-bar-container .left-bar-data2 {
    left: -45px;
    text-align: right;
  }

  .resectable-nsclc .section-10 .hor-bar-container .left-bar-data1 {
    left: -56px;
  }

  .resectable-nsclc .section-10 .bar-chart-horizontal {
    position: relative;
    max-width: 253px;
    margin: 0 auto;
  }

  .resectable-nsclc .section-10 .hor-bar-one {
    min-width: 24px !important;
    left: 0;
    margin-bottom: 17px;
  }

  .resectable-nsclc .section-10 ul.hor-scale {
    left: 0;
    bottom: 23px;
    padding: 0;
    width: 359px;
  }

  .resectable-nsclc .section-10 .hor-ruler {
    width: 9.8%;
    margin-right: 5px;
  }

  .resectable-nsclc .section-10 .hor-bar-two {
    min-width: 212px;
    left: 0;
    margin-bottom: 20px;
  }
/*.resectable-nsclc .section-10 ul.hor-scale {*/
/*    left: 126px;*/
/*    bottom: 22px;*/
/*}*/
/*.resectable-nsclc .section-10 .hor-ruler {*/
/*    width: 8%;*/
/*}*/
  .resectable-nsclc .section-10 .hor-bar-container {
    position: relative;
    max-width: 339px;
    margin: 0 auto;
  }
/*.resectable-nsclc .section-10 .hor-bar-container .left-bar-data2 {*/
 
/*}*/
  .copy-per p {
    font: normal normal 700 62px/19px Barlow !important;
    padding: 24px 0 20px 0;
    letter-spacing: -0.38px;
    line-height: 74px !important;
    margin: 0 !important;
    padding: 0 !important;
  }

  .resectable-nsclc .copy-per p {
    margin-top: 15px;
  }

  .metastatic-nsclc .section-6 .data-copy .copy-per p {
    padding: 22px 0 24px 0;
    line-height: 60px !important;
  }

  .section-10 .brain-section {
    display: block;
    max-width: 302px;
    margin: 45px auto 55px auto;
  }

  .section-10 .hor-bar-one, .section-10 .hor-bar-two {
    left: 0 !important;
  }

  .section-10 .brain-icon-efficacy-mob {
    position: relative;
    top: -37px;
    left: 22px;
  }

  .section-10 .brain-img-txt {
    position: absolute;
    top: 21px;
    color: #fff;
    left: 26px;
    padding: 0;
  }

  .section-10 .img-small-txt {
    margin: 0px 5px 0 0;
  }

  .section-10 .brain-section:after {
    content: "";
    background: #5B305D;
    position: absolute;
    width: 90%;
    height: 141px;
    z-index: -1;
    border-radius: 15px;
    top: 2px;
    left: 15px;
  /*transform: skew(-25deg);*/
    transform: skew(-15deg);
  }

  .section-10 .lg-num {
    padding-left: 24px;
    font-size: 46px;
  }

  .section-10 .copy-txt {
    background: none;
  }

  .section-10.btm-shadow span.ffb-b.cns-text {
    display: block;
    padding-top: 2px;
  }

  .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-1 .accordion.section .accordion-container .az-panel-title p {
    padding: 9px 24px 9px 15px;
  }

  .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-2 .accordion-container .collapse-panel-heading .fa {
    top: 8px;
  }

  .small-txt {
    font-size: 9px;
    line-height: 12px !important;
  }

  .hor-ruler p {
    position: absolute;
    top: 10px;
    left: -4px;
    font-size: 11px;
    color: #262626;
    line-height: 7.58px !important;
  }

  .hor-bar b {
    font-size: 12px;
    font-weight: inherit;
  }

  .section-10 .hor-bar-one p {
    position: absolute;
    right: -60px;
  }

  .section-10 .hor-bar-two.hor-bar p {
    right: -64px;
  }

  .sect-1.txt-ctr img {
    max-width: 115px;
    height: 129px;
  }

  .text.parbase ul.box-unaccept {
    margin-top: 4px;
  }

  .text.parbase ul.box-unaccept {
    margin-top: 4px;
    padding-left: 6px;
  }

  ul.box-unaccept li:before {
    background: #fff;
    content: "";
    width: 3px;
    height: 3px;
    position: absolute;
    left: -8px;
    top: 7px;
    border-radius: 50%;
  }

  ul.box-unaccept li {
    position: relative;
    list-style: none;
    display: block;
    margin: 0;
    line-height: 14px;
    max-width: 113px;
    margin: 0 auto;
    text-align: center;
  }

  table.demographic-table tr:nth-child(10) td:first-child, table.demographic-table tr:nth-child(13) td:first-child {
    line-height: 18px;
  }

  .box-3 span.icons img {
    padding-left: 6px;
  }

  span.icons img {
    margin-bottom: -3px;
  }

  .resectable-nsclc .section-11 .left-img .az-80-pill-bottle {
    position: relative;
    top: 1px !important;
    right: -15px !important;
    width: 60px;
    height: 65px;
  }

  .section-11 .left-img p,.section-11 .right-img p {
    font-size: 14px;
    line-height: 15px !important;
  }

  .section-11 .img-head {
    font-size: 12px;
    line-height: 16px !important;
    width: 72%;
    margin: 0 auto;
    padding-bottom: 10px;
  }

  .section-11 .accordion.section .accordion-container .az-panel-title p {
    padding: 16px 24px 16px 15px;
  }

  .section-12 .green-banner {
    width: 82%;
    padding: 13px 0px 13px 38px;
  }

  .section-13 th,.section-13 td {
    padding: 0 !important;
  }

  .section-13 .patients {
    width: 100%;
    max-width: 393px;
    margin: 0 auto;
  }

  .section-13 .chart-body-copy {
    padding: 10px 15px !important;
  }

  .section-13 .chart-footnote {
    margin: 0 0 40px 0;
    text-indent: 0;
  }

  .section-13 .nccn-content-mob {
    background-color: #f1f1f1;
    padding: 10px 11px;
  }

  .resectable-nsclc .section-13 .nccn-block-mob, .resectable-nsclc .section-15 .nccn-block-mob {
    background: none;
    min-height: 0;
  }

  .resectable-nsclc .section-13 img.nccn-badge, .resectable-nsclc .section-15 img.nccn-badge {
    margin: 0 auto;
    display: block;
  }

  .resectable-nsclc .section-13 span.nccn-content-mob, .resectable-nsclc .section-15 span.nccn-content-mob {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/nccn-white-callout-mob.png) no-repeat center 1px;
  }

  .resectable-nsclc .section-13 span.nccn-content-mob {
    background-size: 100% 190px;
    margin: -55px auto 0;
    padding: 70px 12px 20px;
  }

  .resectable-nsclc .section-15 span.nccn-content-mob {
    background-size: 100% 240px;
    margin: -65px auto 0;
    padding: 65px 20px 10px;
  }

  .resectable-nsclc .section-15 .nccn-block-mob {
    margin-bottom: 28px;
  }

  .resectable-nsclc .nccn-block-mob {
    min-height: 243px;
    max-width: 253px;
    margin: 20px auto;
  }

  .span1 th {
    font-size: 16px;
    line-height: 17px;
    color: #333333;
  }

  .adaura-callout .green-banner {
    width: 80%;
    padding: 0px 0px 0px 35px;
  }

  .section-14 th {
    padding: 0;
  }

  .section-15 .nccn-content-mob {
    font-size: 12px;
    line-height: 15px !important;
    background-color: #f1f1f1;
  }

  .section-15 .rtt-box {
    flex-direction: column;
    margin: 25px auto;
  }

  .section-15 .rtt-section {
  /*width: 92%;*/
    width: 100%;
  }

  .primary-button {
    padding: 9px 36px;
    text-align: center;
  }

  .resectable-nsclc .section-11 img.placebo {
    top: 2px;
    left: 11px;
    position: relative;
    width: 57px;
    height: 63px;
  }

  .metastatic-nsclc .section-1 .eyebrow {
    margin: 34px 0 10px 0;
  }

  .metastatic-nsclc .section-1 .subhead {
    margin: 0 0 20px 0;
  }

  .metastatic-nsclc .section-1 .copy-per,.metastatic-nsclc .section-2 .copy-per {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/yr-shape-white.png) no-repeat;
    width: 118px;
    height: 83px;
    background-size: contain;
    margin: 20px 0 10px 0;
  }

  .resectable-nsclc.efficacy .section-11 .icons img {
    width: 40px;
    height: 40px;
  }

  .metastatic-nsclc .bar-graph1-copy .bottom-content {
    margin-top: 33px;
  }

  .metastatic-nsclc .bar-graph2-copy .bottom-content {
    margin-top: 20px;
  }

  .metastatic-nsclc .section-1 .copy-per p {
    padding: 25px 0 0 0;
    font: normal normal 800 54px/16px Barlow !important;
 /* letter-spacing: -0.32px;*/
    margin-top: -2px;
  }

  .metastatic-nsclc .section-1 .copy-per p {
    font-weight: 700 !important;
    padding-top: 23px !important;
  }

  .metastatic-nsclc .section-1 .yr-txt {
    font-size: 21px !important;
    line-height: 16px !important;
  }

  .metastatic-nsclc .section-1 .copy-content-lg {
    font-size: 25px;
    line-height: 20px;
  }

  .metastatic-nsclc .section-1 .copy-content-med {
    margin-top: 5px;
    display: block;
    margin-bottom: -3px;
    padding:0px 5px;
  }

  .metastatic-nsclc .section-1 .vs-txt {
    color: #333333;
    line-height: 9px;
    display: inline-block;
    margin-top: -7px;
  }

  .metastatic-nsclc .section-1 .accordion.section .accordion-container .az-panel-title p {
    padding: 7px 24px 7px 15px;
  }

  .metastatic-nsclc .section-1  sup {
    font-size: 50% !important;
    top: -0.7em;
  }

  .metastatic-nsclc .copy-content-med {
    font-size: 16px;
    line-height: 20px;
  }

  .metastatic-nsclc .section-1 .hr-txt {
    font-size: 14px;
    line-height: 35px;
  }

  .metastatic-nsclc .section-1 .box-center {
    margin: 30px auto 0;
  }

  .metastatic-nsclc .nccn-lockup-mob {
    margin: 30px 0 0 0;
  }

  .metastatic-nsclc .nccn-mob-content {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/nccn-curve-mob.png) no-repeat;
    max-width: 253px;
    margin: -40px auto 0 auto;
  /*height: 200px;*/
    height: 185px;
  }

  .metastatic-nsclc .nccn-mob-content p {
    padding: 40px 10px 0 15px;
  }

  .metastatic-nsclc p.content.purple-txt sup {
    top: -1em;
    ;
  }

  .metastatic-nsclc .section-1 .copy-content {
    margin: 13px 0 15px 5px;
  }

  .efficacy .section-1 .copy-content {
    margin: 5px 0 12px 0px;
  }

  .efficacy .section-2 .accordion-container .panel-body {
    padding: 0 5px 15px;
  }

  .efficacy .section-3 .accordion-container .panel-body {
    padding: 15px 0;
  }

  .metastatic-nsclc .section-1 .nccn-footnotes {
    width: 100%;
    margin: 20px 0 20px 0 !important;
    text-indent: -2px;
  }

  .metastatic-nsclc .section-1 .last-footnote {
    margin: 0 0 35px 0;
  }
/*.data-copy, .accordion.section,.adaura-acc-section {*/
/*    max-width: 336px !important;*/
/*    margin: 0 auto;*/
/*}*/
  .metastatic-nsclc .section-2 .eyebrow {
    margin: 55px 0 0 0;
  }

  .metastatic-nsclc .section-2 .subhead {
    margin: 43px 0 25px 0;
  }

  .metastatic-nsclc .section-2 .copy-content {
    margin: 0;
    margin-top: 20px;
  }

  .metastatic-nsclc .section-2 .copy-per {
    margin-bottom: 10px;
  }

  .metastatic-efficacy .section-2 .copy-per {
    margin-bottom: -23px;
    margin-top: 13px;
  }

  .metastatic-nsclc .section-2 .lg-num {
    font: normal normal 700 57px/18px Barlow !important;
    line-height: 70px !important;
  }

  .metastatic-nsclc .section-2 .copy-content-lg {
    font-size: 28px;
    line-height: 23px;
    letter-spacing: -0.34px;
  }

  .metastatic-nsclc .section-2 .copy-content-md,.metastatic-nsclc .section-2 .copy-content-sm {
    line-height: 23px;
  }

  .metastatic-nsclc .section-2 .pfs-right-block {
    margin: 5px 0 0 0;
  }

  .metastatic-nsclc .section-2 .pfs-center-block.pfs-block1 {
    margin: 45px auto 0 auto;
  }

  .metastatic-nsclc .section-2 .pfs-center-block.pfs-block2 {
    margin: 15px auto 25px auto;
  }

  .metastatic-nsclc .section-2 .last-footnote {
    margin: 0 0 35px 3px;
  }

  .metastatic-nsclc .section-3 h2 {
    margin: 5px 0 0 0;
  }

  .metastatic-nsclc .section-3 .subhead {
    margin: 27px 0 20px 0;
  }

  .metastatic-nsclc .section-4 .green-banner {
    margin: 20px 0 30px 0;
    width: 88%;
    padding: 18px 0px 18px 38px;
  }

  .metastatic-nsclc .section-5 .last-footnote {
    margin: 0 0 35px 0;
  }

  .metastatic-nsclc .section-6 h1 {
    margin: 55px 0 20px 0;
  }

  .metastatic-nsclc .section-6 .graphic-box {
    height: 564px;
    margin: 100px auto 63px auto;
    border-radius: 15px;
  }

  .metastatic-nsclc .section-6 .graphic-subhead {
    left: 90px;
    top: -71px;
    width: 69%;
    padding-left: 22px;
  }

  .metastatic-nsclc .section-6 .cns-arrow-section {
    flex-direction: column;
    margin: 80px 0 0 0;
  }

  .metastatic-nsclc .section-6 .cns-block {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/cns-arrow-shape.png)no-repeat;
    width: 159px;
    height: 119px;
    margin: 0 0 40px 0;
    padding: 27px 0 0 0;
    transition: 1s all ease-out;
  }

  .metastatic-nsclc .section-6 .cns-block span {
    font-size: 50px;
    line-height: 60px;
    background: none;
    width: auto;
    height: auto;
    padding: 0;
    background-size: 100% auto;
    left: auto;
    position: relative;
    transition: 1s all ease-out;
  }

  .metastatic-nsclc .section-6 .cns-block2 {
    transform: translateY(-130px);
  }

  .metastatic-nsclc .section-6 .cns-block3 {
    transform: translateY(-260px);
  }

  .metastatic-nsclc .section-6 .copy-content-lg {
    font-size: 28px;
    line-height: 27px;
  }

  .metastatic-nsclc .section-6 .copy-content-sm {
    line-height: 27px;
    color: #5A5B5E;
  }

  .metastatic-nsclc .section-6 .is-visible .cns-block2, .metastatic-nsclc .section-6 .is-visible  .cns-block3 {
    transform: none;
  }

  .metastatic-nsclc .section-6 .subhead3 {
    margin: 0 0 30px 0;
  }

  .metastatic-nsclc .section-6 .bullet-list {
    margin: 45px 0 28px 0;
  }

  .metastatic-nsclc .section-6 .subhead4 {
    margin: 47px 0 30px 0;
  }

  .metastatic-nsclc .section-6 .last-footnote {
    margin: 0 0 43px 0;
  }

  .metastatic-nsclc .section-6 .brain-icon {
    margin: 0;
    left: 31px;
    top: -65px;
  }

  .metastatic-nsclc .section-6 .cns-block p {
    top: -29px;
    left: 43px;
  }

  .metastatic-nsclc .section-6 .cns-block1 p {
    left: 30px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-one {
    width: 73px;
    height: 105px;
    left: 12px;
  }

  .bar-graph1-copy {
    position: absolute;
    top: 48px;
    left: 91px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-two.bar-container {
    width: 73px;
    right: 51px;
    height: 116px;
  }

  .metastatic-nsclc .section-6 .is-visible .bar-two.bar-container,.metastatic-nsclc .section-6 .is-visible .bar-one {
    min-height: 0;
  }

  .metastatic-nsclc .section-6 .is-visible .bar.small-bar {
    min-height: 0;
  }

  .bar-graph2-copy {
    left: 95px;
    top: -37px;
  }

  .bottom-content {
    margin: 10px 0 0 0;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar.small-bar {
    top: -24px;
    width: 73px;
    height: 24px;
  }

  .metastatic-nsclc .section-6  p.vertical-txt {
    left: -9px;
    top: -20px;
    font-size: 12px;
    line-height: 14px !important;
  }

  .bar-graph1-copy p,.bar-graph2-copy p {
    margin: 0;
    font-size: 10px;
    line-height: 10px !important;
  }

  .bar-graph1-copy span,.bar-graph2-copy span {
    font-size: 31px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar p {
    font-size: 31px;
    line-height: 20px !important;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar span {
    font-size: 10px;
  }

  .bar-graph2-copy {
    left: 81px;
    top: 1px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt {
    top: -48px;
    width: 100%;
    text-align: center;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt p {
    padding-bottom: 4px;
  }

  .hor-txt1 {
    position: absolute;
    bottom: 0px;
    left: 22px;
  }

  .hor-txt2 {
    bottom: 0px;
    right: 40px;
  }

  .hor-txt {
    font-size: 12px;
    line-height: 14px !important;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph ul.scale {
    top: 12px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
    max-width: 269px;
    margin-left: 47px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
    margin-top: 38px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph li.ruler {
    height: 35px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph hr.ver-line {
    height: 175px;
    margin-top: 15px;
  }

  .metastatic-nsclc .section-6 .hor-bar-container {
    position: relative;
    max-width: 339px;
    margin: 0 auto;
  }

  .metastatic-nsclc .section-6 .hor-bar-one {
    width: 80px;
    height: 74px;
    left: 47px;
  }

  .metastatic-nsclc .section-6 .hor-bar-two {
    width: 206px;
    height: 74px;
    left: 47px;
  }

  .metastatic-nsclc .section-6 .hor-line {
    width: 100%;
    left: 14px;
    max-width: 271px;
    margin: 0 auto;
    height: 216px;
  }

  .metastatic-nsclc .section-6 ul.hor-scale {
    left: 6px;
    bottom: 2px;
  }

  .metastatic-nsclc .section-6 ul.hor-scale {
    max-width: 326px;
    margin: 0 auto 20px;
    left: 0;
    right: 0;
  }

  .metastatic-nsclc .section-6 .bar-chart-horizontal .hor-bar-one p {
    position: absolute;
    right: -36px;
    top: 28px;
  }

  .hor-bar span {
    font-size: 31px;
  }

  .metastatic-nsclc .section-6 .bar-chart-horizontal .hor-bar-two.hor-bar p {
    top: 28px;
    right: -48px;
  }

  .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1,.metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
    font-size: 12px;
    line-height: 14px !important;
  }

  .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
    left: -15px;
    bottom: 152px;
    text-align: right;
  }

  .metastatic-nsclc .section-6 .hor-ruler {
    width: 66px;
  }

  .metastatic-nsclc .section-6 li.hor-ruler:nth-last-child(1) {
    width: 8px;
    right: 4px;
  }

  .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
    bottom: 48px;
    left: -12px;
  }

  .metastatic-nsclc .section-6 .hor-bar-two.hor-bar {
    bottom: 25px;
    margin-bottom: 20px;
    transition: none;
  }

  .metastatic-nsclc .section-6 .hor-bar-one.hor-bar {
    bottom: 119px;
    margin-bottom: 20px;
    transition: none;
  }

  ul.hor-scale {
    width: 100%;
    height: 14px;
    position: absolute;
    left: -7px;
    bottom: -6px;
  }

  .metastatic-nsclc .section-6 .is-visible .hor-bar-one {
    min-width: 0;
  }

  .metastatic-nsclc .section-6 .is-visible .hor-bar-two {
    min-width: 0;
  }

  .metastatic-nsclc .section-7 .green-banner {
    margin: 40px 0 40px 0;
  }

  .metastatic-nsclc .section-8 .last-footnote {
    margin: 0 0 35px 0;
  }

  .metastatic-nsclc .section-9 h1 {
    margin: 55px 0 20px 0;
  }

  .metastatic-nsclc .section-9 .accordion.section {
    margin: 35px auto 35px auto;
  }

  .metastatic-nsclc .section-9 .visit-btn {
    margin: 40px auto;
  }

  .metastatic-nsclc .section-9 .accordion.section .accordion-container .az-panel-title p {
    padding: 18px 24px 18px 15px;
  }

  .metastatic-nsclc .section-9  .endpoint-block {
    margin: 0px 0;
  }

  .metastatic-nsclc .section-9  .endpoint-block p {
    margin-bottom: 15px;
  }

  .metastatic-nsclc .section-9  .primary-button {
    padding: 7px 36px;
  }

  .metastatic-nsclc .section-9  table.customTable {
    margin: 0 !important;
  }

  .metastatic-nsclc .section-9 .customTable td {
    padding: 0 5px !important;
  }

  .metastatic-nsclc .section-9 .customTable th {
    line-height: 19px !important;
    letter-spacing: -0.14px;
    padding-left: 4px;
  }

  .metastatic-nsclc .section-9 .customTable th:last-child {
    text-align: center !important;
  }

  .metastatic-nsclc .flaura-section {
    flex-direction: column;
  }

  .block2 img {
    display: inline-block;
    margin: 0 20px 10px 30px;
  }

  .block1 {
    margin: 0;
  }
#flaura div.flaura-section.mobile-only > div.block2{
  margin-top: -22px;
}
  .block3 {
    display: flex;
    margin: 10px 0 0 0;
  }

  .img1 {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/efficacy-purple-arrow-down.png) no-repeat;
    width: 159px;
    height: 164px;
    margin: 0 0 35px 0;
  }

  .section-9 .img1 {
    margin-bottom: 14px;
  }

  .img2 {
    height: 166px;
    padding: 18px 16px 0 15px;
    width: 161px;
    margin-left: 15px;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/efficacy-grey-arrow-down.png) no-repeat;
  }

  .img2 p:nth-child(2) {
    margin-bottom: 10px;
  }

  .img2 p:nth-child(1) {
    line-height: 15px !important;
  }

  .img2 p:nth-child(2), .img2 p:nth-child(3) {
    line-height: 15px !important;
    letter-spacing: -0.38px;
  }

  .img1 p {
    padding: 53px 30px;
  }

  .metastatic-efficacy .flaura-accordian .panel-body {
    padding: 12px 9px 32px !important;
  }

  .ratio-lg {
    padding-top: 12px;
  }

  img.placebo {
    left: 34px;
    top: 3px;
    position: relative;
  }

  img.az-80-pill-bottle {
    position: relative;
    top: 5px;
    right: 26px;
  }

  .red-83 {
    font-weight: 700;
  }

  th.purple-txt.adaura-table-color:nth-child(1) {
    text-align: left;
    padding-left: 10px;
  }

  th.purple-txt.adaura-table-color {
    color: #5B305D;
  }

  .section-10 .hor-bar-container .left-bar-data2 {
    bottom: 104px;
  }

  .section-10 .hor-bar-two {
    bottom: 68px;
  }

  .section-10 .hor-bar-container .left-bar-data1 {
    bottom: 232px;
  }

  .section-10 .hor-bar-one {
    bottom: 192px;
  }

  .resect-efficacy .section-10 .num-lg {
    font-size: 31px;
  }

  #os .panel-default>.panel-heading+.panel-collapse>.panel-body {
    overflow: hidden;
  }

  #dfs .panel-body img {
    width: auto;
    max-width: 362px;
    margin-left: -10px;
    margin-bottom: -10px;
    margin-top: -5px;
  }

  .surgery-and-treat-icon.mobile-only,.surgery-chemo-treat-icon.mobile-only {
    position: relative;
    top: 8px;
    max-width: 202px;
    max-width: 190px;
    height: 94px;
  }

  .section-11 .sect-7 span {
    line-height: 16px;
  }

  ul.box-unaccept {
    margin-top: 5px;
  }

  span.icons {
    margin-bottom: 12px;
  }

  .dna-icon {
    margin-bottom: 3px !important;
  }

  .icon-head {
    margin-bottom: 4px;
    margin-top: 15px;
  }

  .who-ps {
    line-height: 18px !important;
  }

  .treat-dna-icon {
    position: relative;
    top: 10px;
  }

  .efficacy.resectable-nsclc .section-15 .box-3 .az-280-treat-and-bottle-icon {
    width: 99px !important;
  }
/***********************dfs******************/
  .efficacy.resectable-nsclc .section-4 .final-analysis-link .final-analysis-text a, .efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text a,
.efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text a {
    font: normal normal 700 20px/24px Barlow !important;
  }

  .efficacy.resectable-nsclc .section-4 .final-analysis-link, .efficacy.resectable-nsclc .section-7 .final-analysis-link {
    max-width: 270px;
  }

  .efficacy.resectable-nsclc .section-10 .final-analysis-link {
    max-width: 270px;
  }

  .efficacy.resectable-nsclc .section-4 .final-analysis-link .final-analysis-text, .efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/final-analysis-bg-mobile.png) no-repeat;
    background-size: 269px 60px;
    padding: 15px 25px;
  }

  .efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/final-analysis-bg-mobile.png) no-repeat;
    background-size: 269px 60px;
    padding: 15px 25px;
  }

  .final-analysis-link .final-analysis-text {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/final-analysis-bg-mobile.svg) no-repeat;
    padding: 18px 20px 24px 20px;
    margin-bottom: 0;
  }

  .final-analysis-link {
    max-width: 210px;
    margin: 23px auto 10px;
  }

  .efficacy.resectable-nsclc .section-4 .eyebrow {
    margin-top: 0 !important;
    line-height: 36px !important;
    margin: 55px 0 16px 0;
  }

  .efficacy.resectable-nsclc .section-4 h2.consistent-dfs {
    margin-top: -8px;
  }

  .efficacy.resectable-nsclc .section-4 .subhead2 {
    margin: 40px 0 22px 0;
  }

  .efficacy.resectable-nsclc .section-4 .adj-table {
    margin: 10px auto 38px auto !important;
  }

  .efficacy.resectable-nsclc .section-5 .green-banner {
    margin: 32px 0 25px 0;
  /*width: 85%;*/;
  }

  .efficacy.resectable-nsclc .section-7 .eyebrow {
    margin: -5px 0 0 0;
    line-height: 36px !important;
  }

  .efficacy.resectable-nsclc .section-7 h2.consistent-dfs {
    margin-top: 8px;
  }

  .efficacy.resectable-nsclc .section-4 .stage-61-text .copy-content-lg,
.efficacy.resectable-nsclc .section-4 .stage-61-text .txt-md {
    line-height: 29px;
  }

  .efficacy.resectable-nsclc .section-7 .adaura-km-chart {
    margin: 20px auto 0 auto;
  }

  .efficacy.resectable-nsclc .section-7 .adaura-km-chart .copy-per.hr-image {
    margin-bottom: 0px;
    transform: none;
    padding: 12px;
    height: auto !important;
    margin-top: 10px !important;
  }

  .efficacy.resectable-nsclc .section-7 .adaura-km-chart .surgery-and-treat-icon {
    max-width: 145px;
    height: 92px;
    margin-top: 10px;
  }

  .efficacy.resectable-nsclc .updated-copy-hr p.purple-txt.ffb-b.lg-num {
    padding-top: 0 !important;
    margin-top: 12px !important;
    margin-bottom: 10px !important;
  }

  .efficacy.resectable-nsclc .section-7 .adaura-km-chart p.prior-per {
    margin-bottom: 18px;
  }

  .efficacy.resectable-nsclc .section-7 .adaura-km-chart p.or-txt {
    margin: 124px auto  20px!important;
    display: none;
  }

  #eff-sm-box-fix-a {
  /*position: relative;*/
  /*top: -150px;*/
  /*margin-bottom: -80px;*/
    position: relative;
    top: 0;
    margin-bottom: 10px;
  }

  .efficacy.resectable-nsclc .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-1 .sm-callout p {
    padding: 33px 16px 34px 16px;
  }

  .efficacy.resectable-nsclc .section-7 .adaura-km-chart .sm-callout p {
    margin-bottom: 29px;
  }

  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one.hor-bar {
    margin-bottom: -6px !important;
  }

  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second.hor-bar {
    margin-bottom: 0px !important;
  }

  .efficacy.resectable-nsclc .section-1 .eyebrow.res-text {
    font: 13px/16px Barlow !important;
    opacity: 1;
    font-weight: 500;
    margin: 13px 0 0 0;
  }

  .efficacy.resectable-nsclc .section-1 h2.new-data {
    font: normal normal 800 36px/43px Barlow;
    color: #5B305D;
    opacity: 1;
  }

  h2.egfr-mutation.new-datatwo {
    font: normal normal 20px/31px Barlow;
    color: #5B305D;
  }

  .efficacy.resectable-nsclc .section-10 .hor-bar p b {
    font: normal normal 400 12px/12px Barlow;
  }

  .efficacy.resectable-nsclc .section-4 .subhead {
    margin: 16px 0 28px 0;
  }

  .efficacy.resectable-nsclc .section-4 .subhead2 {
    margin-top: 30px;
  }

  .efficacy.resectable-nsclc .section-1 h2.egfr-mutation.new-datatwo {
    margin-top: 0px !important;
    font-weight: 500;
    line-height: 20px;
  }

  .efficacy.resectable-nsclc .section-1 h2.new-data {
    font-weight: 800;
  }

  .efficacy.resectable-nsclc img.stage-61 {
    width: 100%;
    height: revert;
  }

  .efficacy.resectable-nsclc .section-5 .green-banner p {
    font-weight: 600;
  }

  .efficacy.resectable-nsclc .section-4 .stage61-chart {
    width: 95%;
    margin: 0 auto;
    text-align: center;
  }

  .efficacy.resectable-nsclc .section-1 h2.new-data, .efficacy.resectable-nsclc .section-1 .egfr-mutation.new-datatwo {
    padding: 0;
    margin: 0;
  }

  .resectable-nsclc .section-10 .hor-ruler {
    width: 56px;
    margin-right: 4px;
  }

  .resectable-nsclc .section-10 .hor-ruler:last-child {
    width: 0px;
    right: -8px;
    position: absolute;
    bottom: -3px;
  }

  .efficacy.resectable-nsclc .section-1 .egfr-mutation.analysis-text {
    box-shadow: inset 0px 2px 3px #00000029;
    border: 2px solid #CEDB00;
    border-radius: 8px;
    opacity: 1;
    text-align: center;
    font: normal normal 800 19px/20px Barlow;
    letter-spacing: 0.19px;
    color: #5B305D;
    margin: 15px auto 23px auto;
    padding: 22px;
  }

  .efficacy.resectable-nsclc .section-1 .egfr-mutation.analysis-text {
    box-shadow: inset 0px 0px 3px #00000029;
  }

  .efficacy.resectable-nsclc .section-1 .eyebrow.dfs-eyebrow {
    font: normal normal 14px/18px Barlow !important;
    letter-spacing: 0.14px;
    color: #5B305D;
    margin-top: 0;
    font-weight: 500 !important;
  }

  .efficacy.resectable-nsclc .section-1 .subhead.finaldfsdata {
    text-align: center;
    font: normal normal 800 26px/30px Barlow;
    color: #5B305D;
    padding-top: 16px;
    border-top: 1px solid #5B305D;
    margin-bottom: 5px;
  }

  .efficacy.resectable-nsclc .section-1 .bracket-text {
    text-align: center;
    font: normal normal normal 13px/24px Barlow;
    letter-spacing: 0.13px;
    color: #5B305D;
    margin-bottom: 20px;
  }

  .efficacy.resectable-nsclc .section-1 .copy-per.dfs-copy p {
    font: normal normal 700 52px/16px Barlow !important;
    letter-spacing: -0.31px;
    padding-top: 23px !important;
  }

  .efficacy.resectable-nsclc .section-1 .copy-per {
    margin: 8px 0 0 0px !important;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-copy .copy-content-lg {
    font: 500 22px/16px Barlow !important;
    letter-spacing: -0.13px;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-content .copy-content-lg {
    font: normal normal 800 30px/27px Barlow !important;
    opacity: 1;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-content span.ffb-med.copy-content-med {
    font: normal normal 15px/17px Barlow;
    max-width: 230px !important;
    margin: 0 auto;
    display: block;
    color: #5A5B5E;
    color: #5B305D;
  }

  #eff-table-height-fix-a td, #eff-table-height-fix-a th {
    line-height: 25px;
  }

  .section-4 .adj-table th:first-child {
    width: 154px !important;
    padding: 0px 5px 0px 10px !important;
  }

  .efficacy.resectable-nsclc .section-1 .accordion-group.panel .panel-body {
    padding: 15px 3px 10px 5px;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-content span.percentage-text {
    color: #5A5B5E;
    line-height: 27px !important;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-content {
  /*margin: 5px 0 8px 0px;*/
  /*max-width: 95%;*/
    margin: 7px 13px 14px 13px;
    max-width: 98%;
    display: block;
  }

  .efficacy.resectable-nsclc .section-1 .new-image.seventythreeper {
    max-width: 190px;
    min-height: 208px;
    margin: 0 auto;
    padding: 6px 0 0;
  }

  .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data2 br.mobile-only {
    display: none;
  }

  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content {
    margin: 47px auto 30px auto;
  }

  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box {
    padding: 0;
    min-height: 225px;
  }

  .newsection-content span.tab-row1, .newsection-content span.tab-row4 {
    margin-left: 10px;
  }

  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box {
    position: relative;
    border: 2px solid grey;
    border-radius: 20px;
    padding: 35px 0 0px 0;
    margin: 70px auto 30px auto;
    max-width: 650px;
  }

  .efficacy.resectable-nsclc .section-1 .newsection-content .dfs-content-box .abs-top {
    background: #fff;
    margin: auto;
    top: -38px;
    width: 85%;
  }

  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul {
    padding: 0;
    margin: -12px 2px 0px 23px;
  }

  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li {
    display: inline-block;
    list-style: none;
    width: 32%;
    margin-left: -4px;
    text-align: center;
    padding: 0;
  }

  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li span {
    display: block;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-content-box .subhead {
    position: absolute;
    top: -23px;
    width: 87%;
    left: 0;
    right: 0;
    letter-spacing: -0.09px;
  }

  .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-head {
    font: 700 16px/19px Barlow;
    letter-spacing: -0.54px;
    color: #4E5055;
    text-transform: uppercase;
    border-bottom: 1px solid #707070;
    padding-bottom: 5px;
    padding-left: 0px;
    padding-top: 8px;
  }

  .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row1 {
    font: normal normal bold 36px/43px Barlow;
    letter-spacing: 0px;
    color: #5B305D;
    margin-top: 3px;
  }

  .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row1, 
.efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row4 {
    position: relative;
  }

  .efficacy.resectable-nsclc .section-1 span.tab-row2 {
    font: normal normal 600 13px/16px Barlow;
    letter-spacing: -0.33px;
    color: #5B305D;
    opacity: 1;
    margin-top: -3px;
  }

  .newsection-content span.tab-row5 {
    margin-bottom: 15px !important;
  }

  .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row3 {
    width: 46px;
    height: 9px;
    opacity: 1;
    border-radius: 50%;
    text-align: center;
    display: block;
    margin: 0px auto 17px auto;
    position: relative;
    left: -1px;
    top: 4px;
  }

  .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row4 {
    top: -3px;
    font: normal normal normal 36px/43px Barlow;
    letter-spacing: 0.4px;
    color: #4E5055;
  }

  .efficacy.resectable-nsclc .section-1 span.tab-row5 {
    font: normal normal normal 13px/16px Barlow;
    letter-spacing: -0.33px;
    color: #4E5055;
  }

  .efficacy.resectable-nsclc .section-1 .newsection-content li.years-2, .efficacy.resectable-nsclc .section-1 .newsection-content li.years-3 {
    border-right: 1px solid #707070;
  }

  .efficacy.resectable-nsclc .section-1 p.subhead.median-text {
    margin: 0px 0 20px;
    letter-spacing: -0.09px;
  }

  .efficacy.resectable-nsclc .section-1 .nccn-content-mob {
    padding: 2px 10px 18px;
  }

/* update */

  #resec-nccn-badge-fix-00 {
    background-size: contain;
  }

  #resec-nccn-badge-fix-01 {
    padding: 45px 10px 12px;
    background-size: cover !important;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/nccn-curve-mob.png) no-repeat;
    background-position: top center;
    max-width: 252px;
    margin-top: 60px;
  }

  img#resec-nccn-badge-fix-02 , img#resec-nccn-badge-fix-04 {
    width: 253px !important;
    margin-bottom: -25px;
    height: auto;
  }

  #resec-nccn-badge-fix-03 {
    background: white;
    padding: 0px 8px 25px 12px;
    margin-top: 43px;
    margin-bottom: 20px;
  }

  span#resec-nccn-badge-fix-05 {
    background: white;
    padding: 0px 10px 10px 12px;
    margin-top: 43px;
    font-size: 16px;
    line-height: 20px !important;
  }

  p#surgeon-subhead-margin-b {
    margin-top: 60px;
  }

  div#eff-teal-banner-btm {
    margin-bottom: 60px;
  }

  .efficacy.resectable-nsclc .section-5 .green-banner {
    padding-left: 36px!important;
    width: 79%!important;
    margin: 25px 0 41px -16px!important;
  }

  .efficacy.resectable-nsclc .adaura-callout .green-banner {
    width: 87.5%;
  }

  ul#eff-bullet-rethink-fix {
    margin-left: -23px;
  }

  #eff-bullet-rethink-fix > li::marker {
    color: #008995;
  }

  div#resect-eff-margin-top-a {
    margin-top: 60px;
  }

  p#eff-stage-box-copy-a {
    font-size: 14px;
  }

  span#eff-stage-box-copy-b {
    font-size: 28px;
  }

  .efficacy.resectable-nsclc .subgroup-header-part .consistent-dfs {
    font-size: 30px !important;
  }

  .nccn-eff-footnotes-container-a {
    margin: 0px 10px 0px -30px !important;
  }

  .efficacy ul.median-list-1 {
    margin-bottom: 40px;
  }

  .nccn-eff-footnotes-container-b {
    margin: -15px -15px 0px -14px !important;
  }

  div#sm-box-margin-btm-b {
    margin-top: -5px;
    margin-bottom: -10px;
  }


/* end */

  .efficacy.resectable-nsclc .section-2 .green-banner p {
    padding: 15px 0 18px 0 !important;
    font-weight: 600;
  }

  .efficacy.resectable-nsclc .section-2 .green-banner {
    margin: 40px 0 20px 0 !important;
  }

  .efficacy.resectable-nsclc .section-2 .green-banner {
  /*padding: 0px 0px 0px 28px;*/
    padding: 0px 0px 0px 22px;
  }

  .efficacy.resectable-nsclc .section-3 .dfs-footnote {
    margin-bottom: 35px !important;
  }

  .efficacy.resectable-nsclc .updated-copy-hr {
    margin-bottom: 22px !important;
  }

  .efficacy.resectable-nsclc .section-10 .eyebrow {
    line-height: 36px !important;
    margin: 20px 0 7px 0;
  }

  .efficacy.resectable-nsclc .section-10 .brain-section:after {
    height: 162px;
  }

  .efficacy.resectable-nsclc .section-10 .brain-section {
    max-width: 330px;
  /* margin: 45px auto 80px auto; */
    margin: 50px 11px 74px 11px !important;
  }

  .efficacy.resectable-nsclc .section-10 .lg-num {
    font-size: 54px;
  }

  .efficacy.resectable-nsclc .section-10.btm-shadow span.ffb-b.cns-text {
    line-height: 18px;
    margin-bottom: 2px;
    padding: 0px 26px;
  }

  .efficacy.resectable-nsclc #cns .cns-last-footnotes {
    padding-left: 12px;
  }

  .resect-efficacy .section-10 .num-lg {
    font-size: 34px;
  }

  .efficacy.resectable-nsclc .section-10 .hor-bar p {
    line-height: 12px !important;
    top: 30px !important;
    margin-bottom: 0;
  }

  .efficacy.resectable-nsclc .section-10 .check-box-one {
    margin-bottom: 3px;
  }

  .efficacy.resectable-nsclc .section-10 .bullet-list {
    margin: 25px 0 15px 7px;
  }

  .efficacy.resectable-nsclc #cns .refer-section {
    max-width: 90%;
    margin: 0 auto;
    display: block;
    position: relative;
  }

  .efficacy.resectable-nsclc .section-10 .brain-icon-efficacy-mob {
    top: -38px;
    left: 6px;
    width: 98px;
    height: 98px;
  }

  .efficacy.resectable-nsclc .section-10 .brain-img-txt {
    top: 26px;
    left: 15px;
  }

  .efficacy.resectable-nsclc .section-10 .hor-line {
    margin-top: 5px;
  }

  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one.hor-bar {
    min-width: 66px !important;
    margin-bottom: 0px;
  }

  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second.hor-bar {
    min-width: 53px;
  }

  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two {
    margin-bottom: 5px;
  }

  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second {
    margin-bottom: 6px;
  }

  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two.hor-bar {
    min-width: 165px;
  }

  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two-second.hor-bar {
    min-width: 97px;
  }

  .efficacy.resectable-nsclc .hor-bar-one-second {
    margin: 0 0 23px 0;
    left: 66px;
  }

  .efficacy.resectable-nsclc .hor-bar-two-second {
    background: #AEB0B3;
    min-width: 0px;
    position: absolute;
    height: 92px;
    bottom: 68px;
    left: 499px;
    margin: 0 0 32px 0;
    transition: 1s all ease;
    transition-delay: 1s;
    opacity: 0;
    z-index: 2;
  }

  .efficacy.resectable-nsclc .section-10 .hor-bar p, .efficacy.resectable-nsclc .hor-bar span, 
.efficacy.resectable-nsclc .section-10 .hor-bar-two.hor-bar p {
    color: #ffffff;
    line-height: 12px;
  }

  .efficacy.resectable-nsclc .section-10 .hor-bar-one p, .efficacy.resectable-nsclc .section-10 .hor-bar-one-second p, 
.efficacy.resectable-nsclc .section-10 .hor-bar-two-second p, .efficacy.resectable-nsclc .section-10 .hor-bar-two.hor-bar p {
    top: 30px;
    position: absolute;
    text-align: right;
  }

  .efficacy.resectable-nsclc .section-10 .hor-bar-one p,
.efficacy.resectable-nsclc .section-10 .hor-bar-two-second p {
    right: 9px !important;
  }

  .efficacy.resectable-nsclc .section-10 .hor-bar-one-second p {
    right: 6px !important;
  }

  .efficacy.resectable-nsclc .section-10 .hor-bar-two p {
    right: 10px !important;
  }

  .efficacy.resectable-nsclc .hor-bar-two-second {
    left: 165px;
    margin: 0 0 5px 0;
  }

  .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data1, 
.resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data2 {
    font-size: 12px;
  }

  .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data1 {
    left: -66px;
    bottom: 208px;
  }

  .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data2 {
    left: -70px;
    bottom: 82px;
  }

  .resectable-nsclc.efficacy .section-10 .hor-line {
    width: 256px;
    height: 244px;
  }

  .resectable-nsclc.efficacy .recurrence-section {
    width: 240px;
  }

  .resectable-nsclc.efficacy .recurrence-cns-text, .resectable-nsclc.efficacy .Local-regional-text {
    width: 120px;
  }

  .resectable-nsclc.efficacy .recurrence-section .recurrence-right {
    font-size: 12px;
    line-height: 14px;
    text-align: left;
    padding-left: 7px;
    color: #333333;
  }

  img.stage-61 {
  /* max-width: 135px; */;
  }

  .resectable-nsclc.efficacy .percentage-bar-text {
    font-size: 12px;
    line-height: 19.2px !important;
  }

  .efficacy.resectable-nsclc .section-1 {
    border-top: 8px solid #CEDB00;
  }

  .efficacy.resectable-nsclc .section-15 .footnotes.nccn-footnotes {
    width: 92%;
  }

  .fsd-img-one {
    right: 38px !important;
  }

  .fsd-img-two {
    left: 62px !important;
  }

  .efficacy-gb-sec {
    padding: 0px 0px 0px 38px !important;
  }
}

@media screen and (min-width: 992px) {
    .resect-efficacy #section-5{
        margin-top:-3px;
    }

  /*.resectable-nsclc.resect-efficacy .section-4 .stage-61-text{*/
  /*  margin-left:10px !important;*/
  /*}*/

  .nccn-eff-footnotes-container-a{
    padding-left: 13px;
  }
  .section-3 .last-footnote{
    margin-left: 6px;
  }
    #pfs > div.page-section-inner.container > div:nth-child(4) > div > div.dor-orr-block > div.orr-block > img{
  margin-bottom: 8px;
  }
  #rethink-treatment > div.page-section-inner.container > div.columnControl.section > div.multi-column-container.is-visible > div > div.col-sm-4.col-xs-12.column-1 > div > div > div > img{
    position: relative;
    bottom: 7px;
  }
  #rethink-treatment > div.page-section-inner.container > div.columnControl.section > div.multi-column-container.is-visible > div > div.col-sm-4.col-xs-12.column-2 > div > div > div > img{
    left: 10px;
    top: 5px;
    position: relative;
  }
  .section-4 .stage61-chart{
    padding-right: 50px;
  }

    .resectable-nsclc .column-1 {
    transform: translateY(85px);
    transition: 1s ease-in-out;
}

/*.dom-ready .column-1 {*/
/*    transform: none;*/
/*}*/

.is-visible .column-1 {
    transform: none;
}

.resectable-nsclc .column-2 {
    transform: translateY(100px);
    transition: 1.7s ease-in-out;
}

/*.dom-ready .column-2 {*/
/*    transform: none;*/
/*}*/

.is-visible .column-2 {
    transform: none;
}

.resectable-nsclc .column-3 {
    transform: translateY(145px);
    transition: 2s ease-in-out;
}

/*.dom-ready .column-3 {*/
/*    transform: none;*/
/*}*/
.endpoint-block{
  padding-left: 7px;
}
.is-visible .column-3 {
    transform: none;
}
  #efficacysubgroups > div.page-section-inner.container > div.accordion.section{
    margin-bottom:30px;
  }
  #section-3 > div.page-section-inner.container > div > div > div.visit-btn{
    max-width:550px;
    margin: 35px auto 35px auto;
  }
  .num-txt {
    padding-top: 10px;
    font-size: 69px;
    padding-left: 14px;
  }

  .x-txt {
    position: relative;
    top: -9px;
    font-size: 40px;
  }

  .scale-chart img {
    scale: 1.07;
  }

  h2.unpre-median.first-line {
    margin-top: 5px !important;
  }

  .fn_1 {
    text-indent: -5px;
  }

  .footnotes.fn_2 {
    text-indent: -5px;
  }

  .fn_3 {
    text-indent: -3px;
    padding-left: 6px;
  }

  .ml_4 {
    margin-left: 4px;
  }

  .efficacy .footnotes.mtop_10.nccn-footnotes {
    text-indent: -4px;
  }

  .efficacy.resectable-nsclc #subgroups .panel-group {
    margin-left: -10px;
  }

  .efficacy.resectable-nsclc .section-1 .km-curve {
    right: 2px;
  }

  img.stage-61 {
    max-width: 135px;
    top: 10px;
  }

  .efficacy.resectable-nsclc .section-1 .dfs-copy p.purple-txt.extrabold {
    position: relative;
    top: -4px!important;
    font: normal bold 78px/20px Barlow !important;
    letter-spacing: -0.38px!important;
  }

  .efficacy .flex-2-box {
        /*margin-left: 24px;*/
    margin-left: 14px;
    position: relative;
    left: -2px;
  }

  .section-3 .accordion-container .collapse-panel-heading .fa {
    top: 0px;
  }

  .efficacy .mobile-only-1 {
    display: none;
  }

  .copy-content {
    width: 100%;
  }

  .copy-per {
    max-width: 136px;
    width: 100%;
    margin: 10px 0 0 40px;
    background-size: contain;
    padding: 0;
    bottom: 2px;
    position: relative;
  }

  .copy-per p {
    line-height: 83px !important;
    padding: 0 !important;
    margin: 0 !important;
    text-align: center;
  }

  .metastatic-nsclc .section-1 .copy-per {
    width: 100%;
    padding: 9px 2px 0px 0;
    min-height: 95px;
    background-size: contain;
    height: 95px;
    margin-bottom: 10px;
  }

  .resectable-nsclc .section-1 p.nccn-content {
    height: 106px;
    padding-top: 22px;
    flex: 1;
  }

  .efficacy.resectable-nsclc .section-1 p.nccn-content {
    height: 126px;
    padding-top: 22px;
  }

  .isi-wrapper.open {
    margin-top: 0px;
  }

  .metastatic-nsclc .section-9 .visit-btn a {
    padding: 9px 0;
    padding-right: 65px;
    padding-left: 65px;
    padding-top: 8px;
  }

  .efficacy #eff-ex-txt-fix-d, .efficacy #eff-ex-txt-fix-c {
    font-weight: 400;
  }

  .section-1 .nccn-block {
    margin-left: auto;
    margin-right: auto;
    width: 736px;
  }

  img.adjuvant-chart.desktop-only {
    max-width: 820px;
    height: 220px;
  }

  .section-2 .green-banner p {
    padding-left: 5px;
    font-weight: 600;
  }

  .section-4 .new-image.table-text.graphic-image {
    padding-top: 4px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
    left: 25px;
    margin: 27px auto 58px;
  }

  .metastatic-nsclc .section-6 .bar-chart-horizontal {
    position: relative;
    left: 115px;
  }

  .efficacy .heading-block .line-2 {
    margin: 6px 0px;
  }

  #dfs .copy-content {
    margin-top: 22px;
    width: 100%;
  }

  .efficacy .accordion.section .accordion-container .az-panel-title p {
    padding-bottom: 11px;
    text-align: left;
    padding-left: 22px!important;
  }

  .metastatic-efficacy .section-1 .data-copy .copy-per p {
    padding: 20px 0 12px 0px;
    font-size: 62px !important;
    font-weight: 700 !important;
    line-height: 19px !important;
    padding-top: 20px !important;
  }

  .metastatic-nsclc .section-1 .nccn-footnotes {
    margin-top: 14px;
    margin-left: 70px;
  }

  .metastatic-nsclc #os .panel-body img {
    margin-top: 10px;
  }

  .metastatic-nsclc .section-9 .customTable td:nth-child(1), .metastatic-nsclc .section-9 .customTable th:nth-child(1) {
    padding-left: 20px !important;
  }

  .adaura-box img {
    left: 15px;
    position: relative;
    max-width: 166px;
    height: 106px;
  }

  .column-2 .adaura-box img {
    max-width: 229px;
  }

  .metastatic-nsclc .section-9 .customTable th:nth-child(2) {
    text-align: center !important;
  }

  .resect-efficacy .section-10 .hor-bar-one, .resect-efficacy .section-10 .hor-bar-two {
    left: 93px !important;
    z-index: 6;
    opacity: 0;
  }

  .section-4 .new-image.table-text.graphic-image {
    width: 688px;
    margin: -11px auto 0;
  }

  p.tab-title.center-txt {
    max-width: 362px;
    margin: 0 auto;
    position: relative;
    left: -40px;
  }

  .box-3 {
    transform: translateY(145px);
    transition: 2s ease-in-out;
  }

  .box-2 {
    transform: translateY(100px);
    transition: 1.7s ease-in-out;
  }

  .box-1 {
    transform: translateY(85px);
    transition: 1s ease-in-out;
  }

  .is-visible .rtt-section {
    transform: none;
  }

  .purple-txt.ffb-med,.top-content .ffb-med,
.bottom-content .ffb-med {
    line-height: 18px !important;
  }

/* update start */
  p.nccn-content.nccn-lg.purple-txt.ffb-med.nccn-copy.grey-bg.slide-frm-right.nccn-eff-badge-fix-1 {
    padding: 7px 10px 7px 13px;
    line-height: 15px !important;
    margin-left: 23px;
    background-color: #f1f1f1;
    margin-top: 0;
    margin-bottom: 0;
  }

  #eff-mobile-chart-brain-graphic {
    width: 720px;
  /*padding-bottom: 40px;*/
    padding-bottom: 20px;
  }

  .resec-span-desktop-only {
    white-space: nowrap;
  }

  div#efficacy-2x-banner-fix-a {
  margin: 12px 0px 0px 100px !important;
  /*margin: -39px 0px 0px 100px !important;*/
  }

  p#efficacy-2x-banner-fix-00 {
    margin-bottom: 24px;
  }

  span#efficacy-2x-banner-fix-01 {
    font-size: 38px;
  }

  span#efficacy-2x-banner-fix-02 {
    font-size: 22px;
    color: #5B305D;
  }

  span#efficacy-2x-banner-fix-03 {
    font-size: 18px;
  }

  span#efficacy-2x-banner-fix-04 {
    font-weight: 300;
  }

  .efficacy.resectable-nsclc .section-15 .box-2 .treat-dna-icon {
    width: 95px !important;
    height: auto !important;
    position: relative;
    top: -4px;
  }

  .section-15 h2.consistent-dfs {
    margin: 55px 0 45px 0 !important;
  }

  p.subhead.extrabold.icon-head.eff-icon-height-fix-a {
    line-height: 10px !important;
  }

  div#eff-rtt-fix-a {
    margin: 45px auto 20px !important;
  }

  ul#eff-bullet-rethink-fix {
    margin-left: -25px;
  }

  #eff-bullet-rethink-fix > li::marker {
    color: #008995;
  }

  p#eff-margin-rethink-a {
    margin-top: 15px;
    margin-bottom: 15px;
  }

  #eff-table-height-fix-a td, #eff-table-height-fix-a th {
    line-height: 25px !important;
  }

  .efficacy.resectable-nsclc .section-4 .subhead3 {
    margin: 68px 0 42px 0px !important;
  }

  p#eff-stage-box-copy-a {
    font-size: 14px;
    position: relative;
    top: -8px;
    left: 18px;
  }

  img#eff-stage-box-graphic-a {
    max-width: 235px;
        /* position: relative; */
    top: 7px;
    left: 11px;
  }

  span#eff-stage-box-copy-b {
    font-size: 28px;
  }

  span#eff-stage-box-copy-c {
    font-size: 24px;
  }

  h2#margin-eff-dfs-a {
    margin-top: 90px;
  }

  .efficacy.resectable-nsclc.resect-efficacy h2#margin-eff-dfs-a {
    margin-top: 45px;
  }

  div#eff-nccn-block-margin-b {
    margin: 40px auto;
  }
div#eff-nccn-block-margin-b .polygon{
  height:90px;
  min-width: 163px;
}
  p#surgeon-subhead-margin-b {
    margin-top: 70px;
  }

  div#eff-teal-banner-btm {
    margin-bottom: 60px;
  }

  #adaura-desktop-table-a td:nth-child(1), #adaura-desktop-table-a th:nth-child(1) {
    padding: 0px 30px !important;
    padding-left: 16px!important;
  }

  #adaura-desktop-table-a tr:nth-child(3) td:nth-child(1), #adaura-desktop-table-a tr:nth-child(4) td:nth-child(1), #adaura-desktop-table-a tr:nth-child(5) td:nth-child(1), 
#adaura-desktop-table-a tr:nth-child(7) td:nth-child(1), #adaura-desktop-table-a tr:nth-child(8) td:nth-child(1), #adaura-desktop-table-a tr:nth-child(9) td:nth-child(1) {
    padding-left: 30px!important;
  }


/*update end */
  #section-13 .nccn-copy.grey-bg, #dfs .nccn-copy.grey-bg {
    height: 90px;
  }

  #eff-badge-fix-0 {
    height: 90px;
  }

  #eff-badge-img-fix-0 {
    width: 162px!important;
    position: relative;
    top: -4px;
    height: 90px;
  }

  #eff-badge-img-fix-1 {
    width: 166px!important;
    position: relative;
    top: -2px;
    left: 6px;
    height: 92px;
  }

  .tp-disclaimer {
    /*text-align: center;*/
    text-indent: 0;
  }

  .efficacy.metastatic-nsclc.metastatic-efficacy .section-1 .copy-content {
    /*margin-top: 15px;*/
    margin-bottom: 20px;
    margin-top: 25px;
  }

  .metastatic-nsclc 
     .copy-content-med-new {
    font-size: 16px;
    line-height: 18px;
  }

  .metastatic-nsclc .vs-txt-new {
    font-size: 14px;
        /* line-height: 10px; */
    margin-top: -2px;
    display: block;
  }

  .metastatic-nsclc span.d-block {
    display: block;
    margin-top: -3px;
  }

  .progression-survival-graph img {
    margin-left: 25px;
  }

  .cns-progression-graph img {
    margin-left: -12px;
  }

  .resect-efficacy #eff-resec-target-banner-mobile-margin .heading-block .line-3 {
    letter-spacing: 0.25px;
  }
  
  
 body.fixed-top-margin.efficacy.metastatic-nsclc.metastatic-efficacy.default-fonts.dom-ready  .section-1 .copy-per{
    margin-top: 5px;
    /* margin-bottom: 21px; */
}

body.fixed-top-margin.efficacy.metastatic-nsclc.metastatic-efficacy.default-fonts.dom-ready  .section-2 .copy-per{
    /*margin-top:20px*/
}


p.nccn-content.nccn-lg.purple-txt.ffb-med.nccn-copy.grey-bg.slide-frm-right.nccn-eff-badge-fix-1{
    /*background:#fff;*/
    /*padding:8px 10px 8px 13px;*/
    margin-left:20px;
}
.efficacy.resectable-nsclc .section-15 .nccn-content:before{
    /*background-image:url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/leftcurve-white.png) !important;*/
    /*height:100px !important;*/
    /*background-repeat:no-repeat;*/
    /*background-size:113% !important;*/
}
}

.accordion-group.panel .panel-body {
  padding-top: 20px;
}

#pfs .accordion-group.panel .panel-body {
  padding-top: 20px;
}

#subgroups .accordion-group.panel .panel-body {
  padding-left: 0;
  padding-right: 0;
}

.section-3 .accordion-group.panel .panel-body {
  padding-top: 15px;
}

.percentage-patient {
  position: relative;
  top: -18px;
  line-height: 18px !important;
  color: #262626;
}

.metastatic-efficacy #flaura .flaura-section img {
  max-width: 800px;
  margin: 0 auto;
}

/***********************dfs******************/
.efficacy.resectable-nsclc .section-4 .final-analysis-link .final-analysis-text a, .efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text a,
.efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text a {
  font: normal normal 700 21px/26px Barlow !important;
}

.efficacy.resectable-nsclc .section-4 .final-analysis-link .final-analysis-text, .efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text,
.efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/final-analysis-bg.png) no-repeat;
  padding: 17px 30px 32px 21px;
}

.final-analysis-link .final-analysis-text {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/final-analysis-bg.svg) no-repeat;
  padding: 25px 28px 32px;
}

.efficacy .subgroup-header-part .subgroup-head p {
  margin: 90px 0 16px 0;
}

.efficacy ul.median-list-3 {
  margin-top: 22px;
  margin-bottom: 0;
}

.efficacy .space-t-18 {
  padding: 18px 0 18px 0!important;
  font-weight: 600;
}

.efficacy .subgroup-header-part .subgroup-head h2 {
  margin-bottom: 42px;
}

.efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text, .efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text {
  display: none;
}

.metastatic-nsclc .section-2 .copy-content {
  margin: 20px 0 17px 12px;
}

.metastatic-nsclc .section-6 .data-copy .copy-per {
  padding-left: 10px;
}

.metastatic-nsclc .section-6 .data-copy .copy-content {
  margin-top: 30px;
}

.subgroup-header-part, .with-chemo {
  display: flex;
  position: relative;
  align-items: center;
}

.efficacy.resectable-nsclc .section-10 .img-small-txt {
  display: inline;
  font-size: 16px;
  margin: 6px 0 0 0px;
  line-height: 21px;
}

.efficacy.resectable-nsclc .section-10 .copy-txt {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/76-purple-shape.svg);
  background-repeat: no-repeat;
  background-size: 100%;
  /*max-width: 675px;*/
  max-width: 770px;
  font-size: 18px;
  line-height: 21px !important;
  padding: 10px 0 0 48px;
}

.efficacy.resectable-nsclc .section-10 .lg-txt {
  font-size: 62px;
  line-height: 19px;
  width: 18%;
  /*padding: 16px 0 0 25px;*/
  padding: 20px 0 0 16px;
  height: 55px;
}

.efficacy.resectable-nsclc .section-10 .brain-section .cns-text {
  position: relative;
  display: block;
  margin-top: 2px;
}

.efficacy.resectable-nsclc .section-4 .eyebrow {
  margin: 65px 0 10px 0;
}

.efficacy.resectable-nsclc #with-without-chemo .final-analysis-link {
  top: 44px;
}

.efficacy.resectable-nsclc .final-analysis-link {
  right: -30px;
  margin-top: -30px;
}

.efficacy.resectable-nsclc .section-4 .stage61-chart .copy-content-lg,
.efficacy.resectable-nsclc .section-4 .stage-61-text .txt-md, .efficacy.resectable-nsclc .section-1 .copy-content-sm {
  line-height: 27px !important;
}

.efficacy.resectable-nsclc .stage61-chart .hr-txt, 
.efficacy.resectable-nsclc .section-4 .stage-61-text .copy-content-sm {
  line-height: 17px !important;
}

.efficacy.resectable-nsclc .copy-per.hr-image {
  min-height: 113px !important;
  transform: none;
  padding-top: 11px;
}

.efficacy.resectable-nsclc p.prior-per {
  margin-top: -23px;
  margin-bottom: 15px;
}

.efficacy.resectable-nsclc .section-10 .brain-section {
  margin: 0 11px 44px 0;
  justify-content: center;
}

.efficacy.resectable-nsclc #cns .refer-section {
  max-width: 629px;
  margin: 0 auto;
}

.efficacy.resectable-nsclc .section-1 .eyebrow {
  line-height: 26px !important;
}

.efficacy.resectable-nsclc .section-1 h1.new-data {
  font: normal normal 800 75px/90px Barlow;
  letter-spacing: 0px;
  text-transform: uppercase;
  margin: 0;
  color: #5B305D;
}

.efficacy.resectable-nsclc .section-1 .egfr-mutation.new-datatwo {
  letter-spacing: 0px;
  font-size: 36.5px;
  line-height: 66px;
  font-weight: 500;
  margin: -20px 0 0 0;
  color: #5B305D;
}

.efficacy.resectable-nsclc .section-1 h2.egfr-mutation.analysis-text {
  box-shadow: inset 0px 2px 3px #00000029;
  border: 2px solid #CEDB00;
  border-radius: 14px;
  opacity: 1;
  max-width: 710px;
  margin: 0 auto;
  font: normal normal 800 25px/24px Barlow;
  letter-spacing: 0px;
  color: #5B305D;
  margin-top: 30px;
  padding: 15px 0px 15px;
}

.efficacy.resectable-nsclc .section-1 p.subhead.finaldfsdata {
  font: normal normal 800 25px/26px Barlow;
  letter-spacing: 0px;
  color: #5B305D;
  text-transform: uppercase;
  border-top: 2px solid #5B305D;
  padding-top: 30px;
  max-width: 710px;
  margin: 0 auto;
  margin-top: 33px;
}

.efficacy.resectable-nsclc .section-1 p.bracket-text {
  font: normal normal normal 18px/26px Barlow;
  letter-spacing: 0px;
  color: #5B305D;
  padding-top: 5px;
  margin-bottom: 25px;
}

.efficacy.resectable-nsclc .section-1 .eyebrow.dfs-eyebrow {
  letter-spacing: 0px;
  color: #5B305D;
  font-size: 16px;
  line-height: 24px !important;
  font-weight: normal;
  max-width: 560px;
  display: block;
  margin: 4px auto 0;
}

.efficacy.resectable-nsclc #cns.section-10 .final-analysis-link {
  position: absolute;
  display: block;
  top: 105px;
  right: -85px;
}

.efficacy.resectable-nsclc .section-1 .copy-per {
  margin: 8px 0 0 48px;
}

.efficacy.resectable-nsclc .section-1 .dfs-content .copy-content-lg {
  line-height: 25px !important;
}

.efficacy.resectable-nsclc .section-1 .dfs-copy p.purple-txt.extrabold {
  text-align: center;
  font: normal bold 78px/20px Barlow;
  letter-spacing: -0.38px;
  color: #5B305D;
  /* padding-top: 19px !important; */
  display: flex;
  height: 100%;
  align-items: center;
  justify-content: center;
  position: relative;
  top: -4px;
}

.efficacy.resectable-nsclc .section-1 .copy-content-med {
  font-size: 20px;
  line-height: 25px !important;
  letter-spacing: 0px;
  color: #333333;
  display: block;
  margin-top: -2px;
}

.efficacy .median-list li {
  margin-bottom: 14px;
  max-width: 784px;
}

.efficacy.resectable-nsclc .section-1 .copy-content-med sup {
  top: -0.6em;
  font-size: 62%;
}

.efficacy.resectable-nsclc .section-1 .copy-per .copy-content-lg.yr-txt {
  font-size: 27px;
  line-height: 20px;
  letter-spacing: -0.16px;
}

.efficacy.resectable-nsclc .section-1 .copy-content-sm .percentage-text {
  font-weight: 500;
  color: #5A5B5E;
}

.efficacy.resectable-nsclc .section-1 .accordion.section, .efficacy.resectable-nsclc .section-1 .data-copy {
  max-width: 710px;
}

.efficacy.resectable-nsclc .section-1 .accordion-group.panel .panel-body {
  padding-top: 21px;
  padding-bottom: 15px;
}

.efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content {
  max-width: 497px;
  margin: 50px auto 37px auto;
}

.efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box {
  padding: 0;
  min-height: 245px;
  display: none;
}

.efficacy.resectable-nsclc .dfs-content-box {
  position: relative;
  border: 2px solid #9B9B9B;
  border-radius: 20px;
  padding: 55px 0 30px 0;
  margin: 75px auto 40px auto;
  max-width: 650px;
}

.efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box .abs-top {
  background: #fff;
}

.efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box .subhead {
  position: absolute;
  top: -34px;
  width: 60%;
  left: 0;
  right: 0;
  margin: 0 auto;
  letter-spacing: -0.09px;
}

.efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li .tab-row4 sup,  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li .tab-row1 sup {
  top: -13px;
}

.efficacy.resectable-nsclc .section-1 .newsection-content .dfs-content-box ul {
  margin: 32px 10px 5px 37px;
  padding: 0;
  padding-bottom: 10px;
}

.efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li {
  display: inline-block;
  list-style: none;
  width: 32%;
  margin-left: -4px;
  text-align: center;
  padding: 0;
}

.efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li span {
  display: block;
}

.efficacy.resectable-nsclc .section-1 .newsection-content span.tab-head {
  font: 700 17px/20px Barlow;
  letter-spacing: -0.58px;
  color: #4E5055;
  text-transform: uppercase;
  border-bottom: 1px solid #707070;
  padding-bottom: 7px;
  padding-left: 0px;
  padding-top: 8px;
}

.newsection-content span.tab-row1, .newsection-content span.tab-row4 {
  position: relative;
}

.newsection-content span.tab-row1 {
  font: 700 40px/48px Barlow;
  letter-spacing: 0px;
  color: #5B305D;
  margin-top: 3px;
}

.newsection-content span.tab-row3 {
  width: 46px;
  height: 8px;
  opacity: 1;
  border-radius: 50%;
  text-align: center;
  display: block;
  margin: 1px auto 9px auto;
  position: relative;
  left: 1px;
  top: -1px;
}

.newsection-content span.tab-row1, .newsection-content span.tab-row4 {
  margin-left: 10px;
}

.newsection-content span.tab-row3 {
  margin: 4px auto 12px auto;
}

.newsection-content span.tab-row4 {
  font: normal normal normal 40px/48px Barlow;
  letter-spacing: 0.44px;
  color: #4E5055;
  top: -3px;
}

.newsection-content span.tab-row2 {
  font-weight: 600 !important;
  margin-top: -4px;
}

.newsection-content span.tab-row2,
.newsection-content span.tab-row5 {
  font: normal normal normal 13px/16px Barlow;
  letter-spacing: -0.33px;
  color: #4E5055;
}

.newsection-content li.years-2, .newsection-content li.years-3 {
  border-right: 1px solid #707070;
}

.efficacy.resectable-nsclc .section-1 .subhead.median-text {
  text-align: left;
  max-width: 712px;
  margin: 0 auto;
  letter-spacing: -0.09px;
}

.efficacy .green-banner.ma-top-70 {
  margin-top: 70px!important;
}

.efficacy .fn-dfs {
  max-width: 792px;
}

.efficacy .nccn-bl-footnotes .footnotes {
  padding-left: 0;
  max-width: 736px;
  margin-left: 36px;
}

.efficacy.resectable-nsclc .section-1 .nccn-block {
  margin: 21px auto 0 auto;
  max-width: 736px;
  margin-top: 54px;
  margin-left: 36px;
}

.resectable-nsclc .section-1 p.nccn-content {
  line-height: 20px !important;
  margin-bottom: 3px;
  padding: 22px 26px 15px 20px;
}

.efficacy.resectable-nsclc .section-1 p.nccn-content {
  line-height: 19px !important;
  margin-bottom: 0px;
  /*padding: 6px 21px 4px 19px;*/
  padding: 22px 12px 4px 16px;
  margin-left: 18px;
}

.efficacy.resectable-nsclc .section-1 .nccn-lg.grey-bg:before {
  /*height: 106px;*/
  height: 126px;
}

.efficacy img.nccn-badge {
    /*width: 162px!important;*/
  width: 25% !important;
  height: 120px;
}

#section-13 .efficacy img.nccn-badge {
    /* width: 162px !important; */
  width: 25% !important;
  height: 91px;
}

.is-visible .green-banner {
  transform: translateX(-47px);
}

.green-banner p {
  padding-left: 0px !important;
}

.efficacy.resectable-nsclc .section-10 .hor-line {
  width: 633px;
  margin-top: 10px;
}

.efficacy.resectable-nsclc .section-10 .hor-ruler {
  width: 17.4%;
}

.efficacy.resectable-nsclc .section-10 ul.hor-scale {
  left: 93px;
}

.efficacy.resectable-nsclc .section-10 .hor-bar-container .left-bar-data2 {
  left: -15px;
}

.efficacy.resectable-nsclc .section-10 .hor-bar-container .left-bar-data1 {
  left: -5px;
}

.efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one.hor-bar {
  min-width: 161px;
}

.efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second.hor-bar {
  min-width: 130px;
}

.efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two-second.hor-bar {
  min-width: 240px;
}

.efficacy.resectable-nsclc .hor-bar-one-second {
  margin: 0 0 28px 0;
  left: 254px !important;
}

.efficacy.resectable-nsclc .hor-bar-two-second {
  left: 499px;
  margin: 0 0 32px 0;
}

.efficacy.resectable-nsclc .section-4 .subgroup-head .subhead {
  margin: 38px 0 32px 0;
  font-size: min(1.97vw,22px);
}

.efficacy.resectable-nsclc .section-4 .accordion-group.panel .panel-body {
  padding-top: 23px;
}

.efficacy.resectable-nsclc .section-4 .new-image.table-text.graphic-image {
  /*width: 664px;*/
  /*height: 487px;*/
  /*    width: 679px;*/
  /*height: 469px;*/
  /*margin: 0px auto;*/
      /* width: 664px; */
    /* height: 487px; */
  width: 665px;
  height: 470px;
  margin: 0px auto;
}

.efficacy.resectable-nsclc .section-13 .patient-img.tab-title img {
  height: 410px;
}

.efficacy .with-chemo-head p.eyebrow {
  margin: 0!important;
}

.efficacy.resectable-nsclc .section-1 .km-curve {
  /*width: 680px;*/
  /*height: 304px;*/
  width: 671px;
  height: 438px;
  right: 0px;
  top: -10px;
}

.efficacy.resectable-nsclc .section-4 .subhead3 {
  /*margin: 55px 0 16px 0;*/
  margin: 78px 0 42px 0px;
}

.efficacy.resectable-nsclc .section-5 .green-banner {
  margin: 55px 0 55px 0;
}

.efficacy.resectable-nsclc .section-6 .last-footnote {
  margin: 0 0 42px 0;
}

.efficacy.resectable-nsclc .section-7 .eyebrow {
  margin: 66px 0 0 0;
}

.efficacy.resectable-nsclc .section-7 .adaura-km-chart {
  margin: 23px 0 0 0;
}

.efficacy.resectable-nsclc .updated-copy-hr {
  margin-bottom: 23px !important;
}

.efficacy.resectable-nsclc .section-9 .small-txt {
  margin-bottom: 30px;
}

.efficacy.resectable-nsclc .section-9 .last-footnote {
  margin: 0 0 68px 0;
}

.efficacy.resectable-nsclc .section-10 .eyebrow {
  margin: 70px 0 7px 0;
}

.efficacy.resectable-nsclc .section-10 h2 {
  margin: 0 0 18px 0;
  max-width: 830px;
}

.efficacy.resectable-nsclc .section-10 .last-footnote {
  margin: 0px 0 54px 0;
}

.efficacy.resectable-nsclc .section-10 .bullet-list {
  margin: 35px 0 25px 7px !important;
}

#margin-subbullet {
  margin: 0px 0px 0px 10px !important;
}

.efficacy.resectable-nsclc .section-10 .last-footnote.s-ten {
  margin: 0px 0 40px 0;
  font-weight: 600;
}

.efficacy.resectable-nsclc .section-5 .green-banner p {
  padding: 1px 0 3px 0;
  font-weight: 600;
}

.efficacy.resectable-nsclc .subgroup-header-part .consistent-dfs {
  margin-top: 0px;
  font-size: min(2.7vw,30px);
}

.efficacy.resectable-nsclc .brain-icon-efficacy {
  width: 119px;
  height: 118px;
}

.efficacy.resectable-nsclc .section-4 .accordion.section {
  max-width: 710px;
}

.efficacy.resectable-nsclc .section-4 .stage-61-text {
  margin: 25px 0 0 5px;
  margin-left: -40px;
 
}

.efficacy.resectable-nsclc .with-chemo .consistent-dfs {
  margin-top: 8px;
}

.efficacy.resectable-nsclc .bar-chart-horizontal {
  left: 17px;
}

.efficacy.resectable-nsclc .section-10 .hor-bar .num-lg {
  font: normal normal 700 44px/17px Barlow;
}

.efficacy.resectable-nsclc .section-10 .hor-bar-one p b, 
.efficacy.resectable-nsclc .section-10 .hor-bar-one-second p b {
  font: normal normal 400 15px/17px Barlow;
}

.efficacy.resectable-nsclc .section-10 .hor-bar-two p b, 
.efficacy.resectable-nsclc .section-10 .hor-bar-two-second p b {
  font: normal normal 500 15px/17px Barlow;
}

.efficacy.resectable-nsclc .section-1 {
  /*border-top: 14px solid #CEDB00;*/
  border-top: 12px solid #CEDB00;
}

.efficacy .middle-body {
  margin-top: 40px;
  margin-left: -16px;
}

.efficacy.resectable-nsclc .section-4 .subhead2 {
  max-width: 92%;
}

.resectable-nsclc #with-without-chemo .copy-per {
  padding: 14px 6px 6px;
}

.efficacy.resectable-nsclc .section-15 .box-1 .egfrm-bubble {
  margin-bottom: -5px;
}

.efficacy .footnotes.mtop_10.nccn-footnotes {
  margin-top: 24px!important;
}

.efficacy-test-icon {
  width: 103px !important;
  height: auto !important;
}

@media screen and (min-width: 1600px) {
  .section-10 .hor-line {
    width: 567px;
  }
}



@media screen and (min-width: 347px) and (max-width: 365px) {
   
  .section-4 .accordion.section .accordion-container .az-panel-title p {
    padding: 8px 38px 8px 15px;
  }
}



@media screen and (min-width: 425px) and (max-width: 991px) {
  #dfs .panel-body img {
    margin: 0 auto;
  }
}

@media screen and (min-width: 640px) and (max-width: 767px) {
  .metastatic-nsclc .section-6 .brain-icon {
    left: 27px;
    top: -40px;
  }

  .metastatic-nsclc .section-6 .graphic-subhead {
    left: 90px;
    top: -45px;
    padding: 0 8px 0 68px;
    margin: 0;
  }
}

@media screen and (min-width: 768px) and (max-width: 991px) {
  table.adaura-staging-table th.purple-txt {
    padding: 0 20px;
  }

  .metastatic-nsclc .slide-into {
    display: flex;
    flex-direction: column;
  }

  .metastatic-nsclc .section-2 .pfs-center-block {
    justify-content: initial;
    min-width: 525px;
  }

  .metastatic-nsclc .section-6 .graphic-subhead {
    top: -35px;
    text-align: center;
  }

  .metastatic-nsclc .section-6 .brain-icon {
    left: 77px;
  }

/*.metastatic-nsclc .section-6 ul.hor-scale {*/
/*  left: 202px;*/
/*}*/

  /*.resectable-nsclc .sect-6.txt-ctr {*/
  /*  max-width: 330px;*/
  /*  margin: 0 auto;*/
  /*}*/

  /*.resectable-nsclc .sect-6.txt-ctr .left-img {*/
  /*  min-width: 110px;*/
  /*}*/

  p.or-txt:after {
    bottom: 17px;
  }

  .efficacy.resectable-nsclc p.or-txt:after {
    bottom: 32px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
    margin-left: auto;
  }

  .eff-demographic-chart table.adaura-staging-table th.purple-txt {
    padding: 0px 20px 10px;
    text-align: center;
  }

  .efficacy.resectable-nsclc .section-1 .km-curve .expand-img-mobile.visible-xs-inline-block,
.efficacy.resectable-nsclc .section-1 .km-curve .new-image-mobile,
.efficacy.resectable-nsclc .section-1 .new-image.seventythreeper .expand-img-mobile.visible-xs-inline-block, .efficacy.resectable-nsclc .new-image.seventythreeper,
.efficacy.resectable-nsclc .section-1 .new-image.seventythreeper .new-image-mobile {
    display: block !important;
  }

  .efficacy.resectable-nsclc .section-1 .km-curve .expand-img-desktop.visible-sm-inline-block, .efficacy.resectable-nsclc .section-1 .km-curve .new-image-desktop,
.efficacy.resectable-nsclc .section-1 .new-image.seventythreeper .expand-img-desktop.visible-sm-inline-block, 
.efficacy.resectable-nsclc .section-1 .new-image.seventythreeper .new-image-desktop {
    display: none !important;
  }
}

/*.new-image-mobile {*/
/*    margin-left: -52px;*/
/*}*/

@media screen and (min-width: 991px) and (max-width: 1024px) {
  .metastatic-nsclc .section-6 .is-visible .hor-bar-one,.metastatic-nsclc .section-6 .is-visible .hor-bar-two {
    left: 135px;
  }

  .efficacy.resectable-nsclc img.stage-61 {
    height: 95px;
    width: 135px;
  }
}

@media screen and (min-width: 768px) and (max-width: 1024px) {
  .efficacy.resectable-nsclc .new-image.seventythreeper {
    display: none;
  }
}

table.demographic-table tr:nth-child(8) td:first-child, table.demographic-table tr:nth-child(9) td:first-child {
  padding-left: 40px !important;
}

.metastatic-efficacy .section-6 .cns-progression-vertical-graph sup {
  top: -0.5em;
}

.metastatic-efficacy .section-1 .panel-body {
  padding: 0px;
}

sup.sup-twonum {
  top: -0.9em;
}

.efficacy.resectable-nsclc .final-analysis-link {
  position: relative;
  display: block;
}

.efficacy.resectable-nsclc .final-analysis-link .final-analysis-text a {
  color: #5B305D;
  font: normal normal 700 22px/26px Barlow !important;
  pointer-events: none;
}

.efficacy.resectable-nsclc .final-analysis-link .final-analysis-text {
  background-size: 100% 100%;
  display: inline-block;
  text-align: center;
}

.efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one.hor-bar,
.efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second.hor-bar,
.efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two-second.hor-bar {
  opacity: 1;
}

.efficacy.resectable-nsclc .hor-bar-one-second {
  position: absolute;
  min-width: 0px;
  height: 92px;
  bottom: 186px;
  background: #937794;
  transition: 1s all ease;
  transition-delay: 1s;
  opacity: 0;
  z-index: 2;
}

.efficacy.resectable-nsclc .hor-bar-two-second {
  background: #AEB0B3;
  min-width: 0px;
  position: absolute;
  height: 92px;
  bottom: 68px;
  transition: 1s all ease;
  transition-delay: 1s;
  opacity: 0;
  z-index: 2;
}

.efficacy.resectable-nsclc .section-10 .hor-bar p, .efficacy.resectable-nsclc .hor-bar span, 
.efficacy.resectable-nsclc .section-10 .hor-bar-two.hor-bar p {
  color: #ffffff;
}

.efficacy.resectable-nsclc .section-10 .hor-bar-one p, .efficacy.resectable-nsclc .section-10 .hor-bar-one-second p, 
.efficacy.resectable-nsclc .section-10 .hor-bar-two-second p, .efficacy.resectable-nsclc .section-10 .hor-bar-two.hor-bar p {
  top: 26px;
  position: absolute;
  text-align: right;
}

.efficacy.resectable-nsclc .section-10 .hor-bar-one p {
  right: 20px;
}

.efficacy.resectable-nsclc .section-10 .hor-bar-one-second p, 
.efficacy.resectable-nsclc .section-10 .hor-bar-two p {
  right: 15px;
}

.efficacy.resectable-nsclc .section-10 .hor-bar-two-second p {
  right: 18px;
}

.efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two {
  min-width: 406px;
  background: #555555;
  opacity: 1;
}

.efficacy.resectable-nsclc .updated-copy-hr {
  border: 2px solid #9B9B9B;
  border-radius: 14px;
  border-bottom: 2px solid #9B9B9B;
  border-top-left-radius: 0;
  border-top-right-radius: 0;
  background: #fff;
  margin-bottom: 10px;
}

.efficacy.resectable-nsclc .copy-per.hr-image {
  width: 100%;
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/global/hr-box.png);
  background-repeat: no-repeat;
  margin: 0 auto;
  min-height: 94px;
  background-size: 100%;
  margin-bottom: 30px;
  max-width: 158px;
}

.efficacy.resectable-nsclc .updated-copy-hr p.purple-txt.ffb-b.lg-num {
  font: normal normal bold 60px/72px Barlow !important;
  letter-spacing: -0.36px;
  color: #5B305D;
  opacity: 1;
  text-align: center;
  margin-top: 4px !important;
}

.efficacy.resectable-nsclc p.prior-per {
  font: normal normal normal 15px/18px Barlow !important;
  letter-spacing: 0.38px;
  color: #333333;
  text-align: center;
}

.efficacy.resectable-nsclc .section-7 .adaura-km-chart .column-1:before {
/*height: 279px;*/
/*top: 0px;*/
/*  right: -28px;*/
  height: 372px;
  top: 30px;
  right: -28px;
  display: none;
}

.efficacy.resectable-nsclc .section-7 .adaura-km-chart .column-1:after {
/*top: 92px;*/
/*height: 45px;*/
/*line-height: 50px;*/
/*right: -43px;*/
/*  background: #f1f1f1;*/
  top: 122px;
  height: 50px;
  line-height: 50px;
  right: -43px;
  background: #f1f1f1;
  display: none;
}

.recurrence-cns-text .recurrence-left .check-box-one {
  background-color: #5B305D;
}

.recurrence-cns-text .recurrence-left .check-box-two {
  background-color: #555555;
}

.Local-regional-text .recurrence-left .check-box-one {
  background-color: #937794;
}

.Local-regional-text .recurrence-left .check-box-two {
  background-color: #A0A0A0;
}

.recurrence-right {
  margin-bottom: 10px;
}

.recurrence-left .check-box-one, .recurrence-left .check-box-two {
  width: 16px;
  height: 16px;
}

.recurrence-section {
  display: flex;
  align-items: center;
  justify-content: space-between;
  position: relative;
  width: 505px;
  margin: 0 auto;
}

.recurrence-cns-text, .Local-regional-text {
  display: flex;
  justify-content: space-between;
  position: relative;
  align-items: center;
  width: 212px;
}

.efficacy.resectable-nsclc .section-1 .accordion.section a.collapse-panel-heading {
/*pointer-events: none;*/;
}

.efficacy.resectable-nsclc .section-1 .dfs-accordian span.fa.pull-right.fa-minus {
/*display: none;*/
  display: block;
} 
/*.efficacy.metastatic-nsclc .section-1 .accordion.section a.collapse-panel-heading,
.efficacy.metastatic-nsclc .section-2 .accordion.section a.collapse-panel-heading,
.efficacy.metastatic-nsclc .section-6 .accordion.section a.collapse-panel-heading,
.efficacy.metastatic-nsclc .section-9 .accordion.section a.collapse-panel-heading {
pointer-events: none;
}
.efficacy.metastatic-nsclc .section-1 .accordion.section span.fa.pull-right.fa-minus,
.efficacy.metastatic-nsclc .section-2 .accordion.section span.fa.pull-right.fa-minus,
.efficacy.metastatic-nsclc .section-6 .accordion.section span.fa.pull-right.fa-minus,
.efficacy.metastatic-nsclc .section-9 .accordion.section span.fa.pull-right.fa-minus{
display: none;
}*/

.efficacy.resectable-nsclc .section-1 .green-banner {
  margin: 50px 0 45px 0;
}

.efficacy.resectable-nsclc .section-2 .green-banner {
  margin: 58px 0 25px 0;
}

.efficacy.resectable-nsclc .section-3 .dfs-footnote {
  margin-bottom: 40px;
}

.efficacy.resectable-nsclc .section-10 ul.hor-scale {
  width: 100%;
}

.efficacy.resectable-nsclc .component-section.bg-white.section-1:before {
  box-shadow: 0px 2px 4px #00000045;
}

/*.resectable-nsclc .section-1 p.nccn-content .pink-var {*/
/*  color: #E515DD !important;*/
/*}*/

.efficacy.resectable-nsclc .bg-grey.section-4:before, 
.efficacy.resectable-nsclc .bg-grey.section-10:before,
.efficacy.resectable-nsclc .bg-grey.section-6:after,
.efficacy.resectable-nsclc .bg-grey.section-9:after,
.efficacy.resectable-nsclc .bg-grey.section-15:after,
.efficacy.resectable-nsclc .bg-grey.callout.adaura-callout:after {
  content: "";
  width: 100%;
  height: 3px;
  position: absolute;
  top: auto;
  box-shadow: 0px 0 20px rgb(0 0 0 / 25%);
  background: transparent;
}

.efficacy.resectable-nsclc sup {
  font-size: 60%;
  top: -0.6em;
}

.efficacy.resectable-nsclc .section-4 .stage-61-text .copy-content-sm {
  letter-spacing: 0.35px;
}

.efficacy.resectable-nsclc .section-7 .column-1 .adaura-copy {
  max-width: 120px;
  padding-right: 0px;
}

.newsection-content span.tab-row5 {
  margin-top: -8px;
  margin-bottom: 18px;
}

.efficacy.resectable-nsclc .updated-copy-hr p.purple-txt.ffb-b.lg-num {
  padding: 8px 0 0 !important;
}

.efficacy.resectable-nsclc .footnotes {
  text-indent: -3px;
}

p#eff-footnote-margin-a {
  margin-top: 40px;
}

.stage61-chart .footnotes {
  left: -9px;
}

.dfs-footnote p.footnotes.first-footnote {
  text-indent: -5px;
}

.efficacy.resectable-nsclc .section-15 .box-1 .egfrm-bubble {
  width: 95px;
  height: 103px;
}

.efficacy.resectable-nsclc .section-15 .box-2 .treat-dna-icon {
  width: 106px;
  height: 106px;
}

.efficacy.resectable-nsclc .section-15 .box-3 .az-280-treat-and-bottle-icon {
  width: 93px;
  height: 94px;
}

@media screen and (min-width: 1365px) {
  .efficacy.resectable-nsclc .subgroup-header-part .consistent-dfs,
.efficacy.resectable-nsclc .with-chemo .consistent-dfs {
    width: 710px;
  }
}

@media screen and (min-width: 320px) and (max-width: 361px) {
  .efficacy.resectable-nsclc .section-1 .newsection-content .dfs-content-box .abs-top {
    top: -55px;
  }
}

@media screen and (min-width: 320px) and (max-width: 374px) {
  div#subgroups .panel-body img {
    max-width: 280px;
  }
   .efficacy .yellow-box{
      height: 146px!important;
  }
  .efficacy .b-le, .efficacy .b-re{
              width: 300px !important;
  }
.efficacy.resectable-nsclc .section-5 .green-banner p.callout

 {
        width: auto;
    }
  .surgery-and-treat-icon.mobile-only, .surgery-chemo-treat-icon.mobile-only {
    position: relative;
    top: 15px;
    max-width: 150px;
    height: 69px;
  }

  .efficacy.resectable-nsclc .section-10.btm-shadow span.ffb-b.cns-text {
    margin-right: 20px;
  }

  .metastatic-nsclc #efficacysubgroups .accordion.section .accordion-container .az-panel-title p {
    font-size: 13px;
  }
}

@media screen and (min-width: 413px) and (max-width: 768px) {
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
    margin-left: auto;
  }
}

@media screen and (min-width: 320px) and (max-width: 355px) {
  .metastatic-nsclc .section-1 .callout-box p {
    padding: 0px 0 0 6px;
  }

  .metastatic-nsclc .section-1 .callout-box .vs-txt {
    padding: 0 0 26px 10px;
  }

  .efficacy.resectable-nsclc .section-10.btm-shadow span.ffb-b.cns-text {
    font-size: 14px;
  }
}

@media screen and (min-width: 320px) and (max-width: 373px) {
  .metastatic-nsclc .section-6 .graphic-box {
    margin: 135px auto 63px auto;
  }

  .metastatic-nsclc .section-6 .graphic-subhead {
    top: -120px;
    padding-left: 30px;
  }
}

@media screen and (min-width: 320px) and (max-width: 357px) {
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
    left: 17px;
  }

  .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
    margin-left: 15px;
    margin-right:3px;
  }

  .metastatic-nsclc .section-6 ul.hor-scale {
    max-width: 326px;
  }

  .cns-aura3-vertical-graph {
    max-width: 315px;
    left: 19px;
  /* overflow: hidden; */
    margin-left: 20px;
  }

  hr.ver-line {
    height: 179px;
    width: 245px;
  }

  .metastatic-nsclc .section-6 ul.hor-scale {
    max-width: 266px;
    left: -45px;
  }

  .metastatic-nsclc .section-6 .hor-ruler {
    width: 51px;
  }

  .metastatic-nsclc .section-6 .hor-bar-one {
    width: 80px;
    height: 74px;
    left: 25px;
  }

  .metastatic-nsclc .section-6 .hor-bar-two {
    width: 206px;
    height: 74px;
    left: 25px;
  }

  .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
    bottom: 48px;
    left: -29px;
  }

  .metastatic-nsclc .section-6 .hor-line {
    width: 87%;
    left: 6px;
  }

  .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
    left: -26px;
  }

  .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
    font-size: 10px;
  }

  .block3 {
    display: flex;
    max-width: 311px;
  }

  .img1 {
    background-size: 143px 161px;
  }

  .img2 {
    background-size: 143px 165px;
  }

  #section-7 .green-banner, #section-4 .green-banner {
    width: 83%;
  }
}

@media screen and (min-width: 375px) and (max-width: 413px) {
  .efficacy.resectable-nsclc .section-1 h2.new-data {
    width: 371px;
    margin-left: -18px;
  }

  .resectable-nsclc .section-10 .bar-chart-horizontal {
    margin-left: 62px;
  }

  .resectable-nsclc.efficacy .percentage-bar-text {
    padding-left: 52px;
  }
}

@media screen and (min-width: 376px) {
  .efficacy.resectable-nsclc .section-10 .brain-section {
            /*margin: 50px auto 74px auto!important;*/
             /*margin: 50px auto 64px auto!important;*/
    margin: 40px auto 54px auto!important;
  }
}

.efficacy.resectable-nsclc .section-12.bg-grey:before, .efficacy.resectable-nsclc .section-13.bg-grey:before, 
.efficacy.resectable-nsclc .adaura-callout:before, 
.efficacy.resectable-nsclc .section-7.bg-grey:before, .efficacy.resectable-nsclc .section-9.bg-grey:before {
  display: none;
  box-shadow: none;
}

.efficacy.resectable-nsclc .section-9 .double-footnotes {
  text-indent: -6px;
}

.section-7 .adaura-km-chart .col-md-6.col-sm-12.column-1 .sm-callout p {
  padding: 33px 18px 34px 18px;
}

.efficacy.resectable-nsclc .section-13 .nccn-content:before {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/leftcurve-white.png) no-repeat;
}

.efficacy.resectable-nsclc .section-15 .nccn-content:before {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/leftcurve-grey.png) no-repeat;
  /*background-size: 100% 125px;*/
  background-size: 100% 111px;
  height: 111px;
}

.efficacy.resectable-nsclc .section-13 .nccn-content, .efficacy.resectable-nsclc .section-15 .nccn-content {
  background: #ffffff;
}

p.footnotes.hash-ft {
  text-indent: -4px !important;
}

.efficacy .data-flex-box p {
  margin: 0;
}

.efficacy .heading-block {
  text-align: center;
  margin-top: -25px;
  font-family: 'Barlow', sans-serif;
  margin: 0;
}

.efficacy #section-15 .nccn-copy.grey-bg {
  padding: 7px 35px 7px 15px!important;
}

.efficacy .heading-block .line-1 {
  /*    font: normal normal 21px/25px Barlow;*/
  /*font-weight: 500;*/
  font: normal normal 22px/25px Barlow;
  font-weight: 500;
}

.efficacy .heading-block .line-2 {
      /*font: normal normal 800 63px/55px Barlow;*/
  font: normal normal 800 65px/57px Barlow;
  /* margin: 0px; */
  /*margin: 0px;*/;
}

.efficacy .heading-block .line-3 {
      /*font: normal normal  23px/55px Barlow;*/
  /* margin-left: 25px; */
  /* margin-left: 15px; */
  /*margin-left: 14px;*/
  /*font-weight: 500;*/
  /*color: #5B305D;*/
  /*margin-top: -5px;*/
  font: normal normal  24px/36px Barlow;
  /* margin-left: 25px; */
  /* margin-left: 15px; */
  margin-left: 14px;
  font-weight: 500;
  color: #5B305D;
  /*margin-top: -13px;*/;
}

.efficacy .heading-block .line-3 {
  margin-left: 0;
}

.efficacy .yellow-box {
  /*    box-shadow: inset 0px 3px 6px #00000029, 0px 4px 6px #00000029;*/
  /*border: 2px solid #CEDB00;*/
  /*border-radius: 9px;*/
  /*font: normal normal 16px/18px Barlow;*/
  /*font-weight: 500;*/
  /*padding: 10px 5px;*/
  /*text-align: center;*/
  /*width: 93%;*/
  /*margin: 0 auto;*/
  /*height: 60px;*/
  /*color: #5B305D;*/
  box-shadow: inset 0px 3px 6px #00000029, 0px 4px 6px #00000029;
  border: 2px solid #CEDB00;
  border-radius: 9px;
  font: normal normal 16px/18px Barlow;
  font-weight: 500;
  padding: 8px 5px;
  text-align: center;
  width: 95.7%;
  margin: 0 auto;
  height: 57px;
  color: #5B305D;
  margin-left: 20px;
  margin-top: 10px;
}

.efficacy .yellow-box p {
  font: normal normal 16px/18px Barlow;
  font-weight: 500;
  max-width: 736px;
  color: #5B305D;
  margin: 0 auto;
}

.efficacy .yellow-box b {
  font-weight: 800;
}

.efficacy .astick {
  position: relative;
  top: -2px;
}

.efficacy .data-flex-box {
  display: flex;
  /*margin: 20px 9px 15px;*/
  margin: 20px 0px 15px 6px;
  justify-content: space-around;
}

.efficacy .data-flex-box .data-flex-box-col {
  width: calc(50% - 30px);
}

.efficacy .data-flex-box .above-card-wrap {
  text-align: center;
}

.efficacy .data-flex-box .green-text-line-1 {
  /*    font: normal normal 800 29px/17px Barlow;*/
  /*color: #0E8995;*/
  font: normal normal 800 29px/17px Barlow;
  color: #0E8995;
}

.efficacy .data-flex-box .green-text-line-2 {
  /*    font: normal normal 500 14px/17px Barlow;*/
  /*color: #0E8995;*/
  /*margin: 5px 0px;*/
  font: normal normal 500 14px/17px Barlow;
  color: #0E8995;
  margin: 8px 0px 3px 0px;
}

.efficacy .b-le {
  /*    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/new-box.png) no-repeat;*/
  /*width: 100%;*/
  /*height: 252px;*/
  /*background-size: 100% 100%;*/
  /*background-position: center;*/
  /*position: relative;*/
  /*margin-top: -4px;*/
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/new-box.png) no-repeat;
  width: 100%;
  height: 250px;
  background-size: 100% 100%;
  background-position: center;
  position: relative;
  margin-top: -4px;
}

.efficacy .text-3 {
  font-family: 'Barlow';
  font-size: 19px;
  font-weight: 900;
  color: #ffffff;
  line-height: 17px;
  padding-top: 23px;
  text-align: center;
}

.efficacy .row-1 {
  display: flex;
  padding-top: 40px;
  justify-content: center;
}

.efficacy .row-1 .col-1 {
  width: 97%;
}

.efficacy .row-1 .col-1 .text-4 {
  color: #5B305D;
  font-size: 28px;
  text-align: center;
  display: flex;
  justify-content: center;
}

.efficacy .text-5 {
  /*    color: #5B305D;*/
  /*padding-top: 21px;*/
  /*margin-bottom: -4px;*/
  /*font: normal normal 500 14px/16px Barlow;*/
  /*letter-spacing: -0.5px;*/
  /*line-height: 16px!important;*/
  /*text-align: center;*/
  /* font-size: 14px; */
  /* margin-top: 2px; */
  /*padding-bottom: 4px;*/
  color: #5B305D;
  padding-top: 21px;
  margin-bottom: -4px;
  font: normal normal 13px/16px Barlow;
  /* letter-spacing: -0.5px; */
  line-height: 16px!important;
  text-align: center;
  /* font-size: 14px; */
  /* margin-top: 2px; */
  padding-bottom: 4px;
}

.efficacy .font-b {
  font-weight: bold;
}

.efficacy .text-6 {
  /*    font-family: 'Barlow';*/
  /*font-size: 85%;*/
  /*color: #4F2C5D;*/
  /*text-align: center;*/
  /*font: normal normal 500 14px/16px Barlow;*/
  /*line-height: 16px!important;*/
  font-family: 'Barlow';
  font-size: 85%;
  color: #4F2C5D;
  text-align: center;
  font: normal normal 13px/16px Barlow;
  line-height: 16px!important;
}

.efficacy .b-le .row-2 {
      /*padding-top: 11px;*/
  padding-top: 10px;
}

.efficacy .text-11 {
  /*    text-align: center;*/
  /*font: normal normal normal 14px/17px Barlow;*/
  /* margin: 5px 0; */
  /* letter-spacing: -0.16px; */
  /*color: #5B305D;*/
  /*font: normal normal 500 14px/17px Barlow;*/
  /*line-height: 17px!important;*/
  /*margin: 0px 0px 10px 0px;*/
  text-align: center;
  font: normal normal normal 13px/16px Barlow;
  /* margin: 5px 0; */
  /* letter-spacing: -0.16px; */
  color: #5B305D;
  font: normal normal 13px/16px Barlow;
  line-height: 17px!important;
  margin: 0px 0px 10px 0px;
}

.efficacy .barlow-ex-bold {
  font-weight: 800;
}

.efficacy .b-le .row-3 {
      /* max-width: 358px; */
  /* margin-left: 18px; */
  /* margin-right: 10px; */
  /*max-width: 349px;*/
  /*margin: 0 auto;*/
      /* max-width: 358px; */
  /* margin-left: 18px; */
  /* margin-right: 10px; */
  max-width: 349px;
  margin: 0 auto;
  margin-top: 10px;
}

.efficacy .b-le .row-3 .footnote, .efficacy .b-le .row-4 .footnote {
      /* font: normal normal normal 12px/16px Barlow; */
  font: normal normal normal 13px/15px Barlow!important;
  color: #606060;
  text-align: center;
  letter-spacing: -0.15px;
}

.efficacy .footnote span.en-prd {
  margin-left: -5px;
}

.efficacy .data-flex-box .data-flex-box-col {
      /*width: calc(50% - 30px);*/
  width: calc(50% - 16px);
}

.efficacy .b-re {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/new-box.png) no-repeat;
  width: 100%;
  height: 251px;
  background-size: 100% 100%;
  background-position: center;
  position: relative;
  text-align: center;
  z-index: 9;
}

.efficacy .data-flex-box .data-flex-box-col:nth-child(2) .above-card-wrap {
  margin-top: -13px;
}

.efficacy .pink-text {
  font-weight: normal!important;
}

.efficacy .d-fl {
  display: flex;
  justify-content: center;
  margin-bottom: -3px;
}

.efficacy .d-fl img {
      /* z-index: 99; */
  /* height: 55px; */
  /* position: relative; */
  /* top: 23px; */
  /* right: 56px; */
  z-index: 99;
  height: 54px;
  position: relative;
  top: 28px;
  right: 57px;
}

.efficacy .d-fl p {
  font-family: 'Barlow';
  font-size: 14px;
  line-height: 17px;
  font-weight: 500;
  margin-top: 11px;
  position: relative;
  left: 52px;
}

.efficacy .data-flex-box .data-flex-box-col:nth-child(2) .above-card-wrap .barlow-bold {
  /*    position: relative;*/
  /* left: -44px; */
  /*left: -60px;*/
  /*top: 1px;*/
  position: relative;
    /* left: -44px; */
  left: -55px;
  top: 1px;
    /*left:54px;*/;
}

.efficacy .above-card-wrap .d-fl p span:nth-child(1) {
  margin-bottom: 6px;
}

.efficacy .above-card-wrap .font-style {
  display: block;
  font-weight: 500;
  line-height: 17px;
  font-size: 14px;
  margin-top: 1px;
    /* margin-left: -79px; */
  position: relative;
  left: -52px;
  margin-bottom: 1px;
}

.efficacy .row-1 .col-1 .text-4 span {
  font-size: 52px;
  font-weight: 800;
}

.efficacy .text-3-1 {
  font-family: 'Barlow';
  font-size: 19px;
  font-weight: 900;
  color: #ffffff;
  line-height: 17px;
  padding-top: 23px;
  text-align: center;
  text-transform: uppercase;
}

.efficacy .text-4-1 {
  font: normal normal 800 52px/62px Barlow;
  letter-spacing: -0.52px;
  color: #5B305D;
  margin: 0;
  padding-top: 38px;
  padding-bottom: 17px;
}

.efficacy .text-5-1 {
  font: normal normal 800 28px/20px Barlow;
  letter-spacing: 0px;
  color: #5B305D;
  margin: 6px 0px;
  margin-top: 6px!important;
}

.efficacy .text-6-1 {
  font: normal normal 500 16px/20px Barlow;
  color: #5B305D;
  margin-bottom: 3px;
  margin-top: -2px;
  margin-top: 2px!important;
}

.efficacy .text-7-1 {
  text-align: center;
  font: normal normal normal 13px/16px Barlow;
  /* letter-spacing: -0.16px; */
  color: #5B305D;
  margin-bottom: 7px;
  line-height: 17px!important;
  margin-top: 8px!important;
}

.efficacy .b-re .row-4 {
  margin-top: 8px;
}

.efficacy .b-re .row-4 .footnote {
  max-width: 310px;
  margin: 0 auto;
  text-align: center;
  font: normal normal normal 13px/15px Barlow!important;
  color: #606060;
  /* margin-left: 15px; */;
}

.efficacy .footnote span.en-prd {
  margin-left: -5px;
}

.efficacy .d-fl p span {
  font-size: 29px;
  font-weight: 800;
  color: #0E8995;
  margin-left: 0;
}

.efficacy .border-gr {
  border-top: 1px solid white;
  max-width: 516px;
  margin: 0 auto;
  height: 10px;
  /* display: flex; */
  /* justify-content: center; */
  /* align-items: center; */
  /* margin-left: 78px; */
  /* margin-right: 41px; */;
}

.efficacy .data-copy-txt {
      /*margin-bottom: 25px;*/
          /* margin-bottom: 25px; */
  margin-top: 24px;
  margin-left: -12px;
}

.efficacy ul.median-list {
  padding-left: 18px;
  margin-top: 0px !important;
}

.efficacy ul.median-list-1 {
  padding-left: 18px;
  margin-top: 21px;
}

.efficacy .data-copy-txt p {
  /*    font-family: 'Barlow';*/
  /*font-size: 22px;*/
  /*line-height: 26px!important;*/
  /*letter-spacing: -0.4px;*/
  /*color: #008995;*/
  /*font-weight: 600;*/
  /*text-align: center;*/
  font-family: 'Barlow';
  font-size: 22px;
  line-height: 26px!important;
  letter-spacing: -0.04px;
  color: #008995;
  font-weight: 600;
  text-align: center;
  /* margin-top: 15px; */;
}

.efficacy .b-bold {
  font-weight: 900;
}

.efficacy ul.median-list-1 li {
  margin-bottom: 14px;
  max-width: 742px;
}

.efficacy #accordion-sec-n-1 .panel-body {
  padding-bottom: 0!important;
  padding-left: 0!important;
  padding-right: 0!important;
}

.efficacy #accordion-sec-n-1 .newImage {
      /*padding: 30px 15px 15px 15px;*/
  padding: 10px 15px 15px 15px;
}

.efficacy .graph-data {
  background: #5B305D;
  height: 94px;
  border-radius: 0 0 15px 15px;
}

.efficacy .graph-top-info p {
  height: 30px;
  display: flex;
  justify-content: center;
  align-items: center;
  padding-top: 14px;
  margin-bottom: 16px;
}

.efficacy .graph-top-info sup, .efficacy .graph-btm-info sup {
  font-weight: normal;
  top: -0.7em;
  font-size: 50%;
}

.efficacy .median-list,  .efficacy .median-list li:last-child {
  margin-bottom: 0;
  padding-bottom: 0;
}

.efficacy .brd-btm hr {
  width: 553px;
  /* color: #a3a3a3; */
  background-color: #a3a3a3;
  /* margin-top: 40px; */
  margin: 40px auto 0px;
  margin-bottom: 14px;
  /* margin-bottom: 40px; */
  border-top: 1px solid #999999;
}

.efficacy ul.median-list-5 {
  margin-bottom: 100px;
  padding-inline-start: 20px;
}

.efficacy.resectable-nsclc ul.median-list-5.list-user {
  margin-bottom: 38px;
}

.efficacy.resectable-nsclc .bg-grey.section-6.sec-userr:after {
  box-shadow: none;
}

.efficacy ul.median-list-5 li {
  margin-bottom: 16px;
}

.efficacy ul.median-list-5 li:last-child {
  margin-bottom: 0px;
}

.efficacy ul.median-list li::marker, .efficacy ul.median-list-1 li::marker, .efficacy ul.median-list-5 li::marker, .efficacy ul.ffb-sb li::marker {
  color: #009398!important;
}

.efficacy .graph-btm-info p {
      /* height: 30px; */
  display: flex;
  justify-content: center;
  align-items: center;
  padding-top: 2px;
}

.efficacy .graph-top-info p, .efficacy .graph-btm-info p {
  font-size: 16px;
  line-height: 17px;
  font-family: 'Barlow';
  color: #fff;
  text-align: center;
}

.efficacy .graph-top-info p span:nth-child(2), .efficacy .graph-btm-info p span:nth-child(2) {
  font-weight: 700;
}

.efficacy .ex-txt {
  font-size: 40px;
  font-weight: bold;
  line-height: 17px;
  letter-spacing: -0.36px;
}

.efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .d-none {
  display: none;
}

.efficacy.resectable-nsclc.resect-efficacy .sm-callout  ul.ffb-sb {
  margin-left: 10px;
}

@media screen and (min-width: 645px) and (max-width: 991px) {
  .efficacy.resectable-nsclc .section-1 .newsection-content .dfs-content-box .abs-top {
    top: -18px;
  }

  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul {
    margin-top: -7px;
  }
}

@media screen and (min-width: 500px) and (max-width: 767px) {
  .metastatic-nsclc .brain-img-section {
    max-width: 460px;
    margin: 0 auto;
    left: 0;
  }

  .metastatic-nsclc .section-6 .graphic-subhead {
    padding-left: 35px;
    margin: 0;
  }
}

.btm-shadow:after {
  bottom: -4px;
}

@media only screen and (device-width : 360px) and (device-height : 740px) and (orientation :portrait) {
 
  .metastatic-nsclc .section-6 .hor-line {
    max-width: 260px;
    left: 16px;
  }

  .metastatic-nsclc .section-6 ul.hor-scale {
    max-width: 326px;
    left: 5px;
  }

  .metastatic-nsclc .section-6 .hor-ruler {
    width: 63px;
  }
}

@media screen and (min-width: 350px) and (max-width: 374px) {
  .metastatic-nsclc .section-6 .bar-chart-horizontal {
    width: 100%;
    /* left:1px; */
  }

 .metastatic-nsclc .section-6 .hor-line {
    max-width: none;
    left: 18px !important;
    width: 275px;
  }
  
  .efficacy.resectable-nsclc.resect-efficacy span.line-2.slide-to-top.is-visible {
    font-size:27px !important
}
}

/*@media screen and (min-width: 358px) and (max-width: 374px) {*/
/*  .metastatic-nsclc .section-6 .hor-line {*/
/*    max-width: none;*/
/*    left: 46px;*/
/*    width: 333px;*/
/*  }*/
/*}*/

.cnd-dfs-chart-wrapper {
  margin-bottom: 20px;
}

.efficacy.resectable-nsclc ul.median-list5-one {
  margin-bottom: 55px!important;
}

p.footnotes.nccn-footnotes.o-align {
  text-indent: -4px;
}

h1.adura-eff-head1 {
  margin: -8px 0 0;
}

.efficacy .heading-block .adura-eff-head1 .line-2 {
  margin-top: 3px;
}

@media screen and (max-width: 991px) {

  #rethink-treatment > div.page-section-inner.container > div.columnControl.section > div.multi-column-container.is-visible > div > div.col-sm-4.col-xs-12.column-3 > div > div > p{
    margin-top: 8px;
  }
  
  .cnd-dfs-chart-wrapper {
    margin-bottom: 65px;
  }

  .efficacy .d-fl p {
    left: 50px;
  }

  p#eff-mobile-chart-brain-title {
    text-align: left;
  }

  .mob-p-0 > .page-section-inner.container {
    padding: 0;
  }

  p#eff-margin-rethink-a {
    margin-top: 18px;
  }

  .section-4.mob-p-0 .adj-table th:first-child {
    width: 135px!important;
  }

  .section-4.mob-p-0 .adj-table th {
    width: 105px!important;
  }

  .efficacy.resectable-nsclc .section-10 .brain-section {
    margin-top: 68px!important;
    margin-bottom: 54px!important;
  }

  .progression-survival-graph img {
    margin-top: -6px;
    margin-bottom: -1px;
  }

  .cns-progression-graph img {
    margin-left: -10px;
  }

  .efficacy.resectable-nsclc .green-banner {
    width: 87%;
  }

  .efficacy.resectable-nsclc .section-5 .green-banner {
    width: 89%!important;
  }

  .efficacy.resectable-nsclc .section-12 .green-banner {
    width: 85%;
    margin: 0;
  }

  .efficacy.resectable-nsclc .adaura-callout .green-banner {
    width: 92.5%;
  }

  .efficacy.resectable-nsclc .section-5 .green-banner p.callout {
    width: 280px;
  }

  .efficacy.resectable-nsclc .section-5 .green-banner.m-top-zero.user-s-1 {
    width: 95%!important;
    margin: 0 !important;
  }

  .efficacy.resectable-nsclc .section-13  #margin-eff-dfs-a {
    margin-top: 30px;
  }

  h1.adura-eff-head1 {
    margin: -13px 0 18px;
    line-height: 29px;
  }
}

@media screen and (max-width: 767px) {
  .efficacy .heading-block .line-3 {
    max-width: 318px;
    margin: 0 auto !important;
  }
}

/*@media only screen */
/*  and (min-width: 375px) */
/*  and (max-width: 991px) */
/* and (orientation: portrait) {*/
/* .metastatic-nsclc .section-1 h1.mobile-only span.text-nowrap {*/
/*    white-space: normal;}*/
/*}*/
@media only screen and (min-device-width: 375px) and (max-device-width: 390px) and (-webkit-min-device-pixel-ratio: 2) {
  .metastatic-nsclc .section-1 h1.mobile-only span.text-nowrap {
    display: inline-block;
    ;
  }
}

span.pink-var {
  color: #FF00B1;
}

.resectable-nsclc.resect-efficacy  .multi-column-container {
  margin-bottom: 20px;
  max-width: 820px;
  margin-left: auto;
  margin-right: auto;
  margin-top: 45px;
}

.column-head {
  font: normal normal 800 36px/18px 'Barlow','sans-serif';
  letter-spacing: 0px;
  color: #5B305D;
  margin-top: 6px;
}

.column-head2 {
  margin-top: 30px;
}

.column-head3 {
  margin-top: 20px;
}

.column-3 .footnotes {
  text-align: center;
}

.column-text {
  font: normal normal 500 16px/20px 'Barlow','sans-serif';
  color: #333333;
}

#eff-rtt-fix-a {
  display: none;
}

.metastatic-efficacy .dor-orr-block {
  border: 2px solid #AFB0B3;
  border-radius: 10px;
  max-width: 720px;
  margin: 80px auto 50px;
  position: relative;
  padding: 40px 70px 25px 80px;
}

.metastatic-efficacy .dor-block img,.orr-block img {
  margin-right: 8px;
}

.metastatic-efficacy .os-block .dosingTitle, .dor-orr-block .dosingTitle {
  font-size: 22px;
  color: #008995;
  line-height: 26px;
  background: #f1f1f1;
  padding: 0 10px;
  position: absolute;
  top: -15px;
  left: 65px;
}

.metastatic-efficacy .dor-block, .orr-block {
  justify-content: center;
  align-items: flex-start;
  display: flex;
  margin: 0 auto 20px;
  align-items: center;
}
#pfs div.dor-orr-block > div.orr-block > div{
  width: 374px;
}
.metastatic-efficacy .dor-or-subtext {
  margin: 30px 20px 10px 10px;
  text-align: center;
}

.metastatic-efficacy .dor-or-il {
  display: list-item;
  list-style-type: "\2022";
  padding-left: 4px;
  margin-left: 6px;
}

@media only screen and (max-width:991px) {
#subgroups > div.page-section-inner.container > div.sectionContainer.section > div.component-section.full-width.no-style.callout.is-visible{
  display:none;
}
  
    .metastatic-nsclc .section-1 .nccn-mob-content

 {
    height: 190px;
 }
    .efficacy .primary-button.extra-btn-class {
    padding: 10px 25px 8px 25px;
}
.efficacy .primary-button{
    background-position: 98% center;
}
     .efficacy.metastatic-nsclc.metastatic-efficacy .nccn-mob-content {
        margin: -34px auto 0 auto;
    }
    .efficacy.resectable-nsclc .section-7 .adaura-km-chart .row{
            display: flex;
        gap: 10px;
        flex-direction: column;
        align-items: center;
    }
    .column-text {
  
    max-width: 162px;
    margin: 0 auto;
}

  .metastatic-efficacy .dor-orr-block {
    padding: 40px 0px 10px 8px;
  }

.metastatic-efficacy .os-block .dosingTitle, .dor-orr-block .dosingTitle {
    text-align: center;
    width: 222px;
    top: -58px;
    left: 58px;
    padding: 0px 3px;
  }


  .metastatic-efficacy .dor-block img, .orr-block img {
    margin-right: 4px;
  }

  .metastatic-efficacy .orr-block {
    margin-bottom: 100px;
  }

  .metastatic-efficacy .orr-block p:first-of-type {
    position: relative;
            padding-right: 5px;
  }

  .metastatic-efficacy .orr-block .dor-or-il:nth-of-type(2) {
    /* width: 240px; */
    position: absolute;
    padding-right: 20px;
    top: 90px;
    left: -75px;
  }

  .metastatic-efficacy .orr-block .dor-or-il:nth-of-type(3) {
    position: absolute;
    top: 132px;
    left: -75px;
  }
  
  .green-banner.m-top-zero.user-s-1.left-align {
    left: -20px;
}

.efficacy.resectable-nsclc.resect-efficacy .green-banner::after{
    border-radius:10px 10px 8px 6px !important
}

}



.text-pink {
  color: #FF00BA;

}

#cns-data > div.page-section-inner.container > div:nth-child(6) > div > ul > li:nth-child(1) {
  padding-bottom: 10px;
}
.polygon {
 width: 163px;
 border-radius: 5px;
display: flex;
 background: #5b305d;
 clip-path: polygon(0% 0%, 93% 0%, 99% 48%, 93% 100%, 0% 100%, 0% 50%);
left: 10px !important;
 position: relative;

 justify-content: center;
  align-self: stretch;
align-items: center;
}
.polygon p {
    
  /* height: 100%; */
  text-align: center;
  vertical-align: middle;
  color: #ffffff;
  font-weight: 500;
  padding-right: 4px;
  margin-bottom: 0;
}
#rethink-treatment > div.page-section-inner.container > div.columnControl.section > div.multi-column-container.is-visible{
  max-width: 710px;
}

span.float-study-number
 {
    position: relative;
}

.metastatic-nsclc span.d-block{
  color:#333333
}
.noshadow-top.bg-grey:before{
  display: none;
}

/*Newly*/




div.section .rte-node p.subhead{
    max-width : 750px
}
@media screen and (min-width: 414px) and (max-width: 992px) {
    .efficacy.resectable-nsclc .section-5 .green-banner p.callout

 {
        width: auto;
    }
  .metastatic-nsclc.metastatic-efficacy .section-6 p.vertical-txt {
    left: 10px;
    font-size: 11px;
    line-height: 10px !important;
  }
  .efficacy.resectable-nsclc .section-1 .km-curve {
   
    height: auto!important;
    
  }
  .dor-orr-block .dosingTitle{
    width:auto;
    top:-15px;
    left:23px;
}
}
@media screen and (min-width: 320px) and (max-width: 374px) {
  .section-11 .accordion.section .accordion-container .az-panel-title p {
    padding: 16px 39px 16px 15px;
  }
  .efficacy .b-le, .efficacy .b-re{
      width: 300px !important;
      right:5px;
  }
  .efficacy.resectable-nsclc .section-5 .green-banner p.callout{
      width: 256px;
  }
 .efficacy.resectable-nsclc .section-5 .green-banner p.callout {
        width: 237px;
    }
    .efficacy.resectable-nsclc .section-12 .green-banner {
        width: 78%;
    }
        .efficacy.resectable-nsclc .adaura-callout .green-banner {
        width: 89.5%;
    }
    .efficacy.resectable-nsclc .section-10.btm-shadow span.ffb-b.cns-text{
        padding: 0px 10px;
    }
    .efficacy.resectable-nsclc .green-banner

 {
        width: 82%;
    }
}



 @media screen and (min-width :715px ) and (max-width : 815px){
    #margin-eff-dfs-a {
    max-width : 680px
}
}
@media screen and  (max-width : 620px){
    #margin-eff-dfs-a {
    max-width : 680px
}
}
@media screen and (max-width : 460px){
    #margin-eff-dfs-a {
    max-width : 355px;
        width :100%
}
}

@media screen and (max-width : 765px){
    .resectable-nsclc .sect-6.txt-ctr{
        justify-content : center;
        gap : 100px;
    }
}
@media screen and (max-width : 992px){
   .multi-column-container.adaura-km-chart.is-visible .row{
 display : flex; 
 flex-direction :column; 
 align-items : center;
 justify-content : flex-start
}
    .metastatic-nsclc .section-6 .copy-content-sm{
        line-height: 0.1 
    }
    
    .efficacy.resectable-nsclc .section-4 .stage-61-text{
        left:0px;
    }
    
.efficacy.resectable-nsclc .section-12 .green-banner, .efficacy.resectable-nsclc .adaura-callout .green-banner{
    left:-20px
}

   .efficacy.resectable-nsclc.resect-efficacy #rethink-treatment > div.page-section-inner.container > div:nth-child(2) > div > div.nccn-block-mob.mobile-only > div{
    background:url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/nccn-curve-mob.png) no-repeat !important;
}
.efficacy.resectable-nsclc.resect-efficacy #rethink-treatment > div.page-section-inner.container > div:nth-child(2) > div > div.nccn-block-mob.mobile-only > div span#resec-nccn-badge-fix-05{
    background:#f1f1f1;
}


.efficacy.metastatic-nsclc.metastatic-efficacy #flaura .text.parbase ul.bullet-list:nth-child(2) li{
 margin-right:-5px !important   
}
    
}

@media screen and (max-width : 755px){
    h2.slide-to-top.is-visible.consistent-dfs {
        max-width : 640px
    }
}

@media screen and (max-width : 680px){
    h2.slide-to-top.is-visible.consistent-dfs {
        max-width : 550px
    }
}

@media screen and (max-width : 520px){
    h2.slide-to-top.is-visible.consistent-dfs {
        max-width : 390px
    }
}
@media screen and (max-width : 990px){
    .section-1 .subhead{
            max-width : 680px
    }
    .nowrap{
        white-space:nowrap;
    }
}

@media screen and (max-width : 460px){
    .section-1 .subhead{
            max-width : 345px
    }
}

@media screen and (max-width : 350px ){
    .metastatic-efficacy .orr-block .dor-or-il{
        margin-top: 20px;
    }
    .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-2{
        padding:0px 45px;
    }
    
}
@media screen and (max-width : 325px ){
    .metastatic-efficacy .orr-block .dor-or-il{
        margin-top: 35px;
    }
  
}


@media screen and (max-width : 330px ){
    .section-1 .dosingGraphMob .dosingTitle{
        top : -70px;
        left :30px;
        padding-top:10px;
    }
    .section-1 .dosingGraphMob .dosingTitle.ffb-med{
        left : 16px;
        top:-2px;
        width :240px;
        padding : 0;
        font-size :21px
        
    }
     .dor-orr-block .dosingTitle{
        left:33px;
    }
}
@media screen and (min-width: 355px) and (max-width: 374px) {
    .efficacy .b-le, .efficacy .b-re {
    width: 323px !important;
}
}



 @media screen and ( max-width : 330px){
  span.ffb-med.vs-txt.vs-txt-new, span.ffb-sb.copy-content-med.copy-content-med-new{
   padding : 0 5px;
  }
     .component-section  {
        overflow : hidden;
    }
       .block3.txt-ctr {
        padding-left : 4.5px;
    }
      .section-3 .graphic-box .col2-box p{
               max-width : 110px
     }
 }




@media screen and (max-width : 1200px){
     .top-header .navbar-header .logo img {
    max-width : 200px
    }
   .vertical-list-dropdown .list-dropdown.dropdown-menu li{
     max-width : 300px
    }
 .top-header-links .top-nav ul{
  max-width : 480px;
  position :absolute;
  right : 5px;
  top: -3px
 }
 .therapyToggleWrap{
  max-width : 350px
 }
}
@media screen and (max-width : 1160px){
     .top-header .navbar-header .logo img {
    max-width : 180px
    }
  .vertical-list-dropdown .list-dropdown.dropdown-menu li{
     max-width : 300px
    }
 
 .top-header-links .top-nav ul{
  max-width : 480px;
  position :absolute;
  right : 5px;
  top: -3px
 }
 .therapyToggleWrap{
  max-width : 250px;
 }
}

@media screen and (max-width : 1110px){
  .top-header .navbar-header .logo img {
    max-width : 170px
    }
  .vertical-list-dropdown .list-dropdown.dropdown-menu li{
     max-width : 230px
    }
  .therapyToggleWrap{
  max-width : 245px;
   box-sizing : border-box; 
   padding : 6px 4px
 }
}


@media screen and (max-width : 1120px){
.top-header-links .top-nav ul { 
 max-width : 460px
}
}

@media screen and (max-width : 1080px){
.top-header-links .top-nav ul { 
 max-width : 350px
}

.efficacy.resectable-nsclc.resect-efficacy .top-header-links .top-nav ul{
    max-width:450px
}
}
@media screen and (max-width : 765px){
    .dose-red-sub-list{
        max-width : 680px
    }
}

@media screen and (min-width : 1600px ){
        .is-visible.banner-bg-section::after{
                transform : scalex(2);
                background-position : center 50%;
        }

}

.efficacy.resectable-nsclc .section-1 .copy-content-med.medostxt{
  color:#5B305D;
  font-weight:500
}



@supports (-webkit-touch-callout: none) {
  @media (max-width: 375px) {
    /* iPhone-only styles */
    
#cns h2.slide-to-top.is-visible.consistent-dfs{
    font-size:29px
}
  }
}