/* ------------------------ chemotheraphy Efficacy page styling*/
.metastatic-efficacy .pfs-rate{
    text-indent: initial;
}
.metastatic-efficacy .metastatic-efficacy-ref {
    display: none;
  }
  
  #without-cns .panel-collapse, #with-cns .panel-collapse {
        /*margin-top: 0px;*/
    margin-top: -10px;
  }
  
  .section-9 {
    margin-top: 45px;
  }
  
  #pfs p.chart-copy.margin-bottom-12.desktop-only {
    /* display: none; */
  }
  
  #pfs p.chart-copy.desktop-only{
      margin-bottom: 20px;
  }
  
  sup.mt5 {
    top: -3px;
  }
  
  #additional-results .orr-block p {
    margin-top: -4px;
  }
  
  .metastatic-efficacy p#meta-ffb-txt-fix-align-1::before {
    content: " ";
    position: absolute;
    left: 66%;
    height: 57%;
    border-left: 1px solid #707070;
    top: -25px;
  }
  
  .metastatic-efficacy p#meta-ffb-txt-fix-align-1::after {
    content: " ";
    position: absolute;
    left: 66%;
    height: 57%;
    border-left: 1px solid #707070;
    top: 27px;
  }
  
  .d-none {
    display: none;
  }
  
  .metastatic-efficacy ul.bullet-list.keep-center {
    text-align: center;
    width: 100%;
  }
  
  .metastatic-efficacy ul.bullet-list.keep-center li::before {
    left: 13.5%;
    top: -1px;
  }
  
  .eyebrow.teal-txt {
    color: #008995;
  }
  
  li.pt10 {
    padding-top: 10px;
  }
  
  #subgroups ul.nav.nav-pills.tab-list,
    #cns-data .tabs.section, 
    #efficacysubgroups ul.nav.nav-pills.tab-list {
    display: none;
  }
  
  #cns-data .accordion.section {
    max-width: 713px;
  }
  
  #without-cns {
    margin: 0px 0 42px;
  }
  
  .mb60 {
    margin-bottom: 60px;
  }
  
  .pt0 {
    padding-top: 0 !important;
  }
  
  img.desktop-only.pt0 {
    margin-bottom: 0px !important;
  }
  
  .pb0 {
    padding-bottom: 0 !important;
  }
  
  .component-section.full-width.no-style.callout.callout-grey.section-7.is-visible {
    background: #ffffff;
    margin-bottom: 30px;
  }
  
  ul.bullet-list.chemo-eff-after-tabs.pfs2 {
    margin-left: 0 !important;
  }
  
  .pfs2 li::before {
    display: none;
  }
  
  .mn-nccn-head.nccn-icon.slide-frm-left {
    background: url('/content/dam/open-digital/tagrisso-hcp/us/en/global/nccn-chevron-desktop.png') no-repeat;
    background-size: 100% 100%;
    width: 160px;
    height: 100px;
  }
  
  .nccn-block.desktop-only.slide-into.is-visible {
    margin: 42px auto 40px;
    width: 710px;
    gap: 10px;
  }
  
  .meta-chemo-efficacy .now-approved-art.desktop-only::before {
    content: "";
    display: block;
    width: 101%;
    top: 10px;
    height: 83px;
    /*background-image: url('/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/desktop/chemoApprovedPinkBrac.png');*/
    background-size: cover;
    margin-left: 0px;
    position: absolute;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-1 .eyebrow {
     /* margin: 56px 0 5px 0;*/
    margin: 55px 115px 5px 0;
  }
  
  .meta-chemo-efficacy .extrabold.copy-content-lg.surviva-txt {
    font-size: 28px;
    line-height: 16px;
  }
  
  .meta-chemo-efficacy span.copy-content-lg.ffb-med.yr-txt {
    font-size: 28px;
    font-weight: 600 !important;
  }
  
  .meta-chemo-efficacy span.chemo-chart-txt-med {
    font-weight: 400 !important;
    position: relative;
    /* top: -5px; */
    display: block;
    /*padding-bottom: 7px;*/
  }
  
  .meta-chemo-efficacy span.ffb-med.vs-txt.vs-txt-new {
    /*position: relative;*/
    /*top: -5px;*/
  }
  
  .meta-chemo-efficacy span.chemo-chart-txt-size {
    font-size: 15px !important;
    line-height: 16px !important;
  }
  
  .meta-chemo-efficacy .now-approved-art.mobile-only {
    position: relative;
    left: 82%;
    top: 0px;
  }
  
  .meta-chemo-efficacy.dom-ready .approvedChemo {
    transition-delay: 0.5s;
  }
  
  .meta-chemo-efficacy .now-approved-art.desktop-only {
    position: absolute;
     /* left: 81.5%; */
    left: 84%;
    top: -56px;
  }
  
  .meta-chemo-efficacy .now-approved-art.desktop-only img {
    width: 260px;
  }
  
  .meta-chemo-efficacy .now-approved-art.mobile-only img {
    width: 290px;
  }
  
  .meta-chemo-efficacy ul.bullet-list.chemo-pfs-margin {
    margin-top: -10px;
  }
  
  p.sensitivity-table-header {
    font-size: 14px;
    font-weight: 600;
    line-height: 19px;
    margin-bottom: 5px;
  }
  
  .sensitivity-table-item.violet-txt {
    color: #5B305D;
  }
  
  .sensitivity-table-container {
    display: flex;
    flex-direction: column;
    align-items: center;
    padding: 20px;
    background-color: #F1F1F1;
    max-width: 705px;
    margin: 0 auto;
    margin-bottom: 24px;
    color: #333333;
  }
  
  .sensitivity-table-item span:last-child {
    padding-left: 50px;
  }
  
  .sensitivity-table-item span:first-child {
    padding-left: 20px;
  }
  
  .sensitivity-table-item {
    display: flex;
    justify-content: flex-start;
    width: 67%;
    border-bottom: 1px solid #0000004D;
  }
  
  .sensitivity-table-item-full {
    border-bottom: 1px solid #0000004D;
    width: 67%;
    text-align: center;
    font-size: 16px;
  }
  
  .sensitivity-table-item span {
    flex-basis: 50%;
  }
  
  .sensitivity-table-container ul.bullet-list {
    margin: 20px 0 0 0 !important;
    width: 100%;
    text-align: center;
  }
  
  .sensitivity-table-container ul.bullet-list li:before {
    color: #333;
    position: relative;
    left: auto;
    margin-right: 5px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-1 .last-footnote {
    margin-bottom: 22px;
    padding-left: 3px;
    text-indent: 0;
  }
  
  #efficacysubgroups > div.page-section-inner.container > div:nth-child(6) > div > p:nth-child(3) {
    padding-left: 1px;
  }
  
  .meta-chemo-efficacy .visit-btn {
    width: 460px;
    margin: 40px auto 50px auto;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2  h2.unpre-median {
    padding-bottom: 30px;
  }
    
    /* graph sec 2 */
  .meta-chemo-efficacy.metastatic-nsclc .section-2 span.ffb-b-txt {
    font-size: 34px !important;
    top: -20px;
    position: relative;
    left: 10px;
    letter-spacing: 0.6px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-one p {
    right: -90px;
    top: 27px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2  .hor-bar-two.hor-bar p {
    right: -90px;
    top: 27px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 span.ffb-b-txt-2 {
    font-size: 14.5px !important;
    letter-spacing: 0.29px !important;
    font-weight: 400 !important;
    left: -109px;
    position: relative;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 span.ffb-b.less-weight {
    font-weight: 400 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data2 span.ffb-b {
    color: #46244C;
    font-weight: 400 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-line {
    left: 14px;
    top: 1px;
    width: 578px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-scale {
    width: 97%;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data1 {
    position: absolute;
    bottom: 230px;
    left: 5px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data1 {
    bottom: 205px;
    text-align: right;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data2 {
    bottom: 90px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-one {
    position: absolute;
    min-width: 0px;
    height: 92px;
    bottom: 186px;
    left: 134px;
    background: #5B305D;
    margin: 0 0 28px 0;
    transition: 1s all ease;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-one {
    left: 135px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-two {
    position: absolute;
    min-width: 0px;
    height: 92px;
    bottom: 68px;
    left: 134px;
    background: #AEB0B3;
    margin: 0 0 32px 0;
    transition: 1s all ease;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-two {
    left: 135px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data2 {
    bottom: 93px;
    left: -17px;
    font-size: 18px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .bar-chart-horizontal {
    position: relative;
    margin-top: 22px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data2 {
    position: absolute;
    bottom: 79px;
    left: 12px;
    text-align: right;
    word-spacing: -4px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-line {
    height: 267px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-two.hor-bar {
    min-width: 0px;
    bottom: 42px;
    transition: 1s all ease;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-two {
    min-width: 355px;
    background: #A891A9;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-one.hor-bar {
    min-width: 0px;
    bottom: 167px;
    margin-bottom: 30px;
    transition: 1s all ease;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-one {
    min-width: 560px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-ruler {
    width: 14.95%;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-ruler:first-child {
    left: 1px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 p.tab-title.center-txt {
    left: 10px;
    top: 15px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar span {
    font-size: 55px;
    line-height: 32px;
    color: white;
  }
    /* graph sec 2 end */
    
    /* circle sec 2 */  
  .meta-chemo-efficacy .circles-wrapper {
    display: flex;
    justify-content: center;
    column-gap: 90px;
    height: 330px;
  }
  
  .meta-chemo-efficacy .circle-container {
    display: flex;
    flex-direction: column;
    align-items: center;
  }
  
  .meta-chemo-efficacy .circle img {
    width: 244px;
    max-height: 244px;
  }
  
  .meta-chemo-efficacy .center-number-circle {
    font-size: 57px;
    position: relative;
    top: -150px;
    color: #46244C;
    font-weight: 800;
    font-family: 'Barlow';
    left: 5px;
  }
  
  .meta-chemo-efficacy span.center-number-circle.circle-lighter {
    font-weight: 500;
  }
  
  .meta-chemo-efficacy .small-text-circle {
    font-size: 14.5px;
    color: #46244C;
    font-weight: 500;
    font-family: 'Barlow';
    position: relative;
    top: -145px;
  }
  
  .meta-chemo-efficacy .medium-text-circle {
    font-size: 18px;
    position: relative;
    top: -50px;
    color: #46244C;
    text-align: center;
    line-height: 18px;
    font-family: 'Barlow';
  }
  
  .meta-chemo-efficacy span.percent-circle {
    font-size: 30px;
    position: relative;
    top: -22px;
  }
  
  .meta-chemo-efficacy p.circles-title {
    font-size: 15px;
    font-weight: 600;
    line-height: 19px;
    text-align: center;
    color: #333333;
    padding: 60px 0px 5px 0px;
    font-family: 'Barlow';
  }
    
    /* circle sec 2 end */
    
  .meta-chemo-efficacy.metastatic-nsclc .section-2 .subhead {
    margin: 23px 0 15px 0;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2  ul.bullet-list.bullet-list-dash {
    padding: 15px 0 15px 5px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 ul.subsequentTreatment ul.bullet-list-dash {
    padding: 0 0 15px 5px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-2 ul.bullet-list-dash li:before {
    content: '\2014';
    left: -15px;
  }
    
    /* tabs */
  .meta-chemo-efficacy.metastatic-nsclc .tab-container {
    max-width: 722px;
    margin: 0 auto;
    padding: 10px 0px 0;
    border: 0;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .nav-pills {
    border-bottom: 2px solid #5B305D;
    margin-bottom: 0px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .nav-pills>li>a {
    font-weight: bold;
    border-bottom: 0;
    font-family: 'Barlow';
    background: #E2DBE3;
    border: solid 1px #0000004D;
    border-radius: 10px 10px 0 0;
    font-size: 14px;
    color: #5B305D;
    top: -2px;
    margin-right: 10px;
    padding: 10px 25px;
    text-align: center;
    line-height: 16px !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .nav-pills>li.active>a, .meta-chemo-efficacy.metastatic-nsclc .nav-pills>li.active>a:focus, .meta-chemo-efficacy.metastatic-nsclc .nav-pills>li.active>a:hover {
    font-weight: bold;
    border-bottom: 0;
    font-family: 'Barlow';
    background: #5B305D;
    border: solid 1px #5B305D;
    border-radius: 10px 10px 0 0;
    font-size: 14px;
    color: white;
    border-bottom-style: none;
    padding: 10px 25px;
    text-align: center;
    line-height: 16px !important;
    text-decoration: underline;
  }
  
  .flaura-tabs-wrapper.EGFR-mutation-type {
    margin: 25px 0 15px !important;
  }
  
  .EGFR-mutation-type-inner {
    border: 1px solid #707070;
    border-radius: 12px;
    text-align: center;
    max-width: 340px;
    position: relative;
    padding-bottom: 10px;
  }
  
  .EGFR-mutation-type-inner .type-content {
    display: flex;
    padding: 28px 0 5px;
    align-items: center;
  }
  
  .EGFR-mutation-type-inner .EGFR-heading {
    font-size: 20px;
    line-height: 26px;
    color: #008995;
    font-weight: 600;
    font-family: 'Barlow';
    position: absolute;
    left: 0;
    right: 0;
    top: -15px;
    background: #f1f1f1;
    max-width: 200px;
    margin: 0 auto;
  }
  
  .EGFR-mutation-type-inner .type-content .type-content-inner h3 {
    font-size: 16px;
    line-height: 17px;
    color: #5B305D;
    font-weight: 700;
    font-family: 'Barlow';
    margin: 0;
    padding: 0 23px;
  }
  .EGFR-mutation-type-inner .type-content .type-content-inner h3.no-mono{
    padding: 0px 40px 17px 40px;
  }
  
  .EGFR-mutation-type-inner .type-content .type-content-inner h2 {
    font-size: 66px;
    line-height: 66px;
    font-weight: 800;
    color: #5B305D;
    font-family: 'Barlow';
    margin: 0;
  }
  
  .EGFR-mutation-type-inner .type-content .type-content-inner h4 {
    font-size: 14px;
    line-height: 17px;
    color: #333333;
    font-family: 'Barlow';
    margin: 0;
  }
  
  .EGFR-mutation-type-inner .months-hr {
    font-size: 22px;
    line-height: 24px !important;
    color: #5B305D;
    font-weight: 600;
    font-family: 'Barlow';
    margin: 0 0 2px;
  }
  
  .EGFR-mutation-type-inner .type-content .hr60 {
    font-size: 16px;
    line-height: 21px;
    color: #333333;
    font-family: 'Barlow';
  }
  
  .ft-wt-500 h3, .ft-wt-500 h2, .ft-wt-500 h4 {
    font-weight: 500 !important;
  }
  
  span.and::before {
    content: '';
    width: 1px;
    position: absolute;
    height: 42px;
    background: #707070;
    top: 31px;
    left: 11px;
    right: 0;
    margin: 0 auto;
  }
  
  span.and::after {
    content: '';
    width: 1px;
    position: absolute;
    height: 42px;
    background: #707070;
    bottom: 70px;
    left: 11px;
    right: 0;
    margin: 0 auto;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .flaura-tabs-wrapper {
    max-width: 722px;
    margin: 0 auto;
    /* border-radius: 0 0 15px 15px; */
    /* border: solid 1px #0000004D; */
    display: flex;
    justify-content: space-evenly;
    flex-wrap: wrap;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .flaura-tabs-wrapper img {
    max-width: 100%;
    padding: 10px;
      /* background-color: #ffffff; */
    border-radius: 0 0 15px 15px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .nav-pills>li.active>a, .meta-chemo-efficacy.metastatic-nsclc .section-6 .nav-pills>li.active>a:focus, .meta-chemo-efficacy.metastatic-nsclc .section-6 .nav-pills>li.active>a:hover {
    padding: 8px 15px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .nav-pills>li>a {
    padding: 8px 15px;
  }
    
    /* tabs end */
    
    /* vertical bar */
    
    
  .meta-chemo-efficacy.metastatic-nsclc .section-6   hr.ver-line {
    border-left: 1px solid #A0A0A0;
    height: 329px;
    border-bottom: 1px solid #A0A0A0;
    border-top: 0 none;
    margin-top: 80px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6  .cns-progression-vertical-graph hr.ver-line {
    height: 337px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph ul.scale {
    top: 25px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph li:first-child.ruler {
    margin-top: -24px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph li.ruler {
    height: 84px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .is-visible .bar-one {
    min-height: 260px;
    width: 101px;
    background: #5B305D;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar.small-bar {
    background: #B8A6B9;
    width: 101px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 
    .bar.small-bar.bar-two {
    min-height: 100px;
    top: -40px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-two.bar-container {
    background: #5B305D;
    width: 101px;
    min-height: 240px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt {
    position: absolute;
    top: -110px;
    left: 6px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt:nth-of-type(2) {
    position: absolute;
    top: -127px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .bar-graph1-copy {
    position: absolute;
    top: 36px;
    left: 200px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .bar-graph2-copy {
    position: absolute;
    left: 118px;
    top: -15px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .bottom-content {
    margin: 150px 0 0 0;
    text-align: center;
    line-height: 17px !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6  .bottom-content .ffb-reg, .meta-chemo-efficacy.metastatic-nsclc .section-6 .bar-graph2-copy .bottom-content .ffb-med {
    position: relative;
    top: -67px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .ffb-b {
    font-weight: 600 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 p.vertical-txt {
    position: absolute;
    top: -50px;
    bottom: 0;
    left: 9px;
    transform: rotate(270deg);
    text-align: center;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .hor-txt1 {
    position: absolute;
    bottom: -13px;
    left: 32px;
    font-size: 18px;
    font-weight: 700 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .hor-txt1 span {
    font-weight: 500 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6  .hor-txt2 {
    position: absolute;
    bottom: -14px;
    right: 159px;
    color: #46244C;
    font-size: 18px;
    font-weight: 500 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6  p.ffb-b.purple-txt.cfas-graph-a {
    font-weight: 700 !important;
    margin-top: 32px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6  span.ffb-med.nowrap.purple-txt.cfas-graph-a1 {
    display: block;
    text-align: center;
    position: relative;
    top: 8px;
    right: 5px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 span.ffb-b.purple-txt.cfas-graph-b {
    font-weight: 700 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 p.purple-txt.ffb-med.cfas-graph-b1 {
    display: block;
    position: relative;
    left: -5px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 span.ffb-b.purple-txt.cfas-graph-c {
    font-weight: 700 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 p.ffb-med.purple-txt.cfas-graph-c1 {
    display: block;
    position: relative;
    left: -5px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 p.ffb-reg.cfas-graph-d {
    color: #5B305D;
    font-weight: 500 !important;
    margin-top: 32px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 span.ffb-med.nowrap.cfas-graph-d1 {
    color: #5B305D;
    font-weight: 500 !important;
    display: block;
    position: relative;
    left: -8px;
    top: 8px;
    text-align: center;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 span.ffb-med.cfas-graph-e {
    color: #5B305D;
    font-weight: 500 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6  p.ffb-med.cfas-graph-e1 {
    color: #5B305D;
    font-weight: 500 !important;
    display: block;
    position: relative;
    left: -10px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6  span.ffb-reg.cfas-graph-f {
    color: #5B305D;
    font-weight: 500 !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6  p.ffb-med.cfas-graph-f1 {
    color: #5B305D;
    font-weight: 500 !important;
    display: block;
    position: relative;
    left: -8px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 p.tab-title.head-wrap.ffb-sb.meta-chemo-eff-vertical-graph-title {
    margin-bottom: -4px !important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6  .bottom-content.btm-content-2 {
    margin-top: 170px !important;
  }
    
    
    /*vertical bar end */
    
  .meta-chemo-efficacy.metastatic-nsclc  h2.slide-to-top.unpre-median.first-line.is-visible {
    margin-bottom: 30px !important;
    position: relative;
  }
  .meta-chemo-efficacy.metastatic-nsclc  h2.slide-to-top.unpre-median.first-line{
      position: relative;
  
  }
  #cns-data > div.page-section-inner.container > div:nth-child(5) > div > div > h2{
    margin: 60px 0 30px 0 !important;
  }
  .meta-chemo-efficacy.metastatic-nsclc .section-3 ul.bullet-list.align-after-panel-chemo {
    padding-top: 15px;
    margin-bottom: 10px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-3 ul.bullet-list.align-after-panel-chemo.forestPlotBullet {
    margin-left: 33px !important;
    margin-right: 20px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 .bullet-list.chemo-eff-after-tabs {
    margin: 20px 0 40px 10px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .cycles-graphic-wrapper img {
    width: 100%;
    padding: 20px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper img {
    width: 100%;
    padding: 30px 0 20px 0;
  }
  
  .desktop-only.BarChart1.BarChart11 {
    position: absolute;
    top: 70px;
    max-width: 280px;
    left: 110px;
    text-align: center;
  }
  
  .cns-responses-chemo-wrapper {
    position: relative;
  }
  
  .desktop-only.BarChart1.BarChart11 p {
    font-size: 16px;
    line-height: 16px;
    color: #5B305D;
    font-family: 'Barlow';
    font-weight: 700;
    margin-bottom: 2px;
  }
  
  .desktop-only.BarChart1.BarChart11 span {
    font-size: 12px;
    line-height: 14px;
    color: #333333;
    font-weight: 400;
    display: inline-block;
  }
  
  .desktop-only.BarChart1.BarChart11.bar2 {
    left: auto;
    right: 40px;
  }
  
  .desktop-only.BarChart1.BarChart11.bar2 p {
    font-weight: 500;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc  .chemo-eff-spacer-30 {
    padding-bottom: 30px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc  .chemo-eff-spacer-20 {
    padding-bottom: 20px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc  p.chemo-eff-after-cns-table.footnotes {
    padding-top: 0;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc  .chemo-eff-spacer-40 {
    padding-bottom: 40px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc  .section-6  .eyebrow {
    padding-top: 55px;
  }
  
  #pfs > div.page-section-inner.container > div:nth-child(10) > div > p:nth-child(8) {
    text-indent: -9px;
  }
  
  .meta-chemo-efficacy p.cns-responses-chemo-title {
    font-size: 15px;
    font-weight: 600;
    line-height: 19px;
    text-align: center;
    color: #333333;
    padding: 20px 0px 0px 0px;
    margin-bottom: -20px;
    font-family: 'Barlow';
  }
  
  .meta-chemo-efficacy p.cns-responses-chemo-title b {
    font-weight: 800;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-9 .eyebrow.chemo-spacer-top {
    padding-top: 10px;
  }
  .meta-chemo-efficacy.metastatic-nsclc .section-9 .eyebrow.chemo-spacer-top:last-child {
    padding-top: 50px;
    padding: 55px 0 0 0;
  }
  .meta-chemo-efficacy.metastatic-nsclc span.ffb-b.chemo-sm-endpoints-txt {
    font-size: 11.5px;
    font-weight: 200 !important;
    margin-top: -10px;
    display: block;
    padding-bottom: 5px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc p.chemo-sm-endpoints-txt-1 {
    padding-bottom: 5px;
  }
  
  .accordion-group p.chart-copy {
    color: #333333;
    font-size: 16px;
    text-align: center;
      /*line-height: 18px !important;*/
    line-height: 33px !important;
  }
  
  .accordion-group .margin-bottom-12 {
    margin-bottom: -12px !important;
  }
  
  .panel.panel-default.az-accordion-panel.verticalSlide p {
    /*padding-bottom: 15px !important;*/
    padding-bottom: 0px;
    /*margin-bottom: 0px;*/
    ;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc span.ffb-b.chemo-blue-endpoints-txt {
    color: #008995;
    display: block;
    margin-top: -10px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-9 .accordion.accordion-container.flaura-accordian.chemo-eff.horizontal {
    margin-top: -20px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-3 ul.bullet-list.meta-chemo-eff-after-egfr-table {
    margin-bottom: 10px;
    margin-top: 10px;
  }
    
    /* callout sec */
  #meta-chemo-eff-callout div.section-blur-layer {
    background: white !important;
  }
  
  div #meta-chemo-eff-callout.callout.bg-white .container {
    margin-top: -40px !important;
    margin-bottom: -30px !important;
  }
    
    /* callout sec end */
    
    /* cns response table */
    
  .meta-chemo-efficacy .cns-response-table th {
    font-weight: bold;
  }
  
  .meta-chemo-efficacy .cns-response-table {
    width: 100%;
    font-family: 'Barlow';
    font-size: 14px;
    line-height: 16px;
    color: #333333;
    margin-top: 0px !important;
  }
  
  .meta-chemo-efficacy .cns-response-table .cns-pink {
    color: #5B305D;
  }
  
  .meta-chemo-efficacy .cns-response-table th, .meta-chemo-efficacy .cns-response-table td {
    border: none;
    padding: 6px;
    text-align: center;
  }
  
  .meta-chemo-efficacy .cns-response-table th {
    font-weight: normal;
  }
  
  .meta-chemo-efficacy .cns-response-table th:first-child {
    border-bottom: 1px solid #9B9B9B;
    border-right: 1px solid #9B9B9B;
    border-top: 1px solid #9B9B9B;
    text-align: left;
    padding-left: 1.5rem;
  }
  
  .meta-chemo-efficacy .cns-response-table th:nth-child(2) {
    border-bottom: 1px solid #9B9B9B;
  }
  
  .meta-chemo-efficacy .cns-response-table th:nth-child(3) {
    border-bottom: 1px solid #9B9B9B;
  }
  
  .meta-chemo-efficacy .cns-response-table th:last-child {
    border-bottom: 1px solid #9B9B9B;
    border-left: 1px solid #9B9B9B;
    border-top: 1px solid #9B9B9B;
  }
  
  .meta-chemo-efficacy .cns-response-table tbody td {
    border-top: none;
  }
  
  .meta-chemo-efficacy table.cns-response-table thead tr td:last-child {
    border-bottom: 1px solid #9B9B9B;
  }
  
  .meta-chemo-efficacy .cns-response-table tbody td:first-child {
    border-top: none;
    text-align: left;
    font-weight: normal;
    border-right: 1px solid #9B9B9B;
    padding-left: 0;
  }
  
  .meta-chemo-efficacy table.cns-response-table thead tr td.ffb-b {
    border-right: 1px solid #9B9B9B;
    border-bottom: 1px solid #9B9B9B;
  }
  
  .meta-chemo-efficacy .cns-response-table tbody td:nth-child(2) {
    border-right: 1px solid #9B9B9B;
  }
  
  .meta-chemo-efficacy .cns-response-table tbody tr:last-child td {
    border-bottom: 1px solid #9B9B9B;
  }
  
  .meta-chemo-efficacy .cns-response-table td.table-border-right {
    border-right: 1px solid #9B9B9B;
  }
  
  .meta-chemo-efficacy .cns-response-table thead td:first-child {
    border-right: 1px solid #9B9B9B;
  }
  
  .meta-chemo-efficacy .cns-response-table-wrapper {
    margin: 0 auto;
    max-width: 677px;
  }
    
    /* cns response table end */
    /*post-hoc table*/
  .metastatic-nsclc .section-3 h2.pfs-medium {
    margin-bottom: 40px !important;
  }
  
  .meta-chemo-efficacy .posthoc-table th.chart-head3.text-left.ffb-b.table-flaura2-pink-charac-header {
    top: 3px!important;
    color: #4a4b4d;
    font-size: 18px;
  }
  
  .meta-chemo-efficacy .posthoc-table .table-flaura2-pink-header {
    padding: 0 16px 5px 16px !important;
    min-width: 159px;
    line-height: 18px !important;
  }
  
  .posthoc-table {
    table-layout: fixed !important;
  }
  
  .posthoc-table td {
    border: 1px solid #8a8c91 !important;
  }
  
  .posthoc-table td:first-child {
    border-left: none!important;
    color: #4a4b4d;
  }
  
  .posthoc-table td:first-child span {
    font-weight: 500;
  }
  
  .posthoc-table td:nth-child(2) {
    background-color: #e9eaeb;
  }
  
  .posthoc-table td:last-child {
    border-right: none!important;
    color: #4a4b4d;
  }
  
  table.posthoc-table > thead > tr > th:nth-child(4) {
    text-align: center !important;
  }
  
  table.posthoc-table > thead > tr > th:nth-child(3) {
    font-weight: 600 !important;
  }
  
  table.posthoc-table > thead > tr > th span {
    font-weight: 400;
  }
  
    /* flaura2 patient demo table */
  .meta-chemo-efficacy .flaura2-demo-table  .table-flaura2-pink-header {
    color: #5B305D;
    text-align: center !important;
    padding: 0px 50px;
    vertical-align: bottom;
    padding-bottom: 5px;
  }
  
  .clinicopathologic-tbl th.chart-head3.text-left.ffb-b.table-flaura2-pink-header {
    padding: 0px 24px 6px 24px!important;
    line-height: 19px !important;
  }
  
  .meta-chemo-efficacy .flaura2-demo-table th.chart-head3.text-left.ffb-b.table-flaura2-pink-charac-header {
    position: relative;
    top: 17px;
  }
  
  .meta-chemo-efficacy .flaura2-demo-table .section-9 .customTable td:nth-child(1) {
    background: none;
  }
  
  .meta-chemo-efficacy .flaura2-demo-table .section-9 tr.table-flaura2-bg-gray {
    background: #F1F1F1;
  }
  
  .meta-chemo-efficacy table.flaura2-demo-table td {
    line-height: 18px;
    letter-spacing: 0.16px;
     /*letter-spacing: -0.2px;*/
    padding: 10px !important;
  }
  
  .meta-chemo-efficacy table.flaura2-demo-table tr.doubleBorderBottom td {
    border-bottom: 2px solid #333333;
  }
  
  .meta-chemo-efficacy  .flaura2-demo-table td.table-flaura2-pink {
    color: #5B305D;
  }
    
    /*.meta-chemo-efficacy  table.flaura2-demo-table tr.table-flaura2-bg-gray {
    background: #f1f1f1 !important;
    }
    
    .meta-chemo-efficacy.metastatic-nsclc .flaura2-demo-table td:nth-child(1) {
    background: none !important;
    }
    .meta-chemo-efficacy.metastatic-nsclc .flaura2-demo-table .table-flaura2-bg-gray  {
     background: #F1F1F1;
    }
    
    .meta-chemo-efficacy.metastatic-nsclc .flaura2-demo-table tr.table-flaura2-special-grey {
    background: #F1F1F1;
    }*/
  .meta-chemo-efficacy.metastatic-nsclc .flaura2-demo-table td.table-flaura2-ident {
    text-indent: 3rem!important;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .flaura2-demo-table td.table-flaura2-bg-pink {
    background: #E2DBE3 !important;
  }
    
    /*.meta-chemo-efficacy.metastatic-nsclc .flaura2-demo-table tr.table-flaura2-special-grey {
    border-bottom: hidden;
    }*/
    
    /* flaura2 patient demo end table */
    
  .meta-chemo-efficacy.metastatic-nsclc  .section-2 .last-footnote {
    margin: 0px 42px 50px 0;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-3 .bullet-list.chemo-eff-after-tabs {
    margin: 30px 0 10px 10px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-9 .m-cta .internal-link, .meta-chemo-efficacy.metastatic-nsclc .section-9 .r-cta .internal-link {
    font-size: 14px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-9 .multi-column-container.meta-chemo-efficacy-internal-cta {
    padding: 40px 70px;
    margin-top: 20px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 ul.chemo-eff-after-vertical-graph {
    margin-top: -20px;
  }
  
  /*.meta-chemo-efficacy.metastatic-nsclc .section-6 ul.chemo-eff-after-vertical-graph li:first-child {*/
  /*  margin-bottom: 15px;*/
  /*}*/
  
  .meta-chemo-efficacy.metastatic-nsclc .section-6 ul.chemo-eff-after-vertical-graph li:last-child {
    /* margin-bottom: -15px; */
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-9 .subhead {
    margin-top: -10px;
    padding-bottom: 10px;
  }
  
  .meta-chemo-efficacy.metastatic-nsclc .section-9 .cycles-graphic-wrapper img {
    width: 100%;
    padding: 20px 0px 0px 0px;
    margin-bottom: -15px;
  }
  
  .cta.r-cta.cenalitx-nwcl, .cta.m-cta.cenalitx-nwcl {
    padding-right: 54px;
    margin-left: auto !important;
  }
  
  .efficacy.metastatic-nsclc .columnControl.section .column-2 {
    padding-left: 0;
    padding-right: 0px;
  }
  
  @media screen and (max-width:768px) {
      
    .meta-chemo-efficacy .cns-response-table th:first-child {
      padding-right: 5px;
      width: 30.5%;
      padding-left: 5px;
    }
  
    .meta-chemo-efficacy .cns-response-table {
      margin-bottom: 35px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .extrabold.copy-content-lg.surviva-txt {
      font-size: 28px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-1 .copy-content-med {
      margin-top: 10px;
      padding: 0px 11px;
    }
  
    .meta-chemo-efficacy span.chemo-chart-txt-height {
      line-height: 18px !important;
    }
  
    .meta-chemo-efficacy .now-approved-art.mobile-only {
      left: 19px;
      top: -40px;
      width: 100%;
    }
  
    .meta-chemo-efficacy .now-approved-art.mobile-only img {
      width: 280px;
      margin: 0 auto -70px auto;
      position: relative;
      left: 0px;
    }
  
    .sensitivity-table-container {
      font-size: 16px;
      padding: 20px 20px 15px 20px;
    }
  
    p.sensitivity-table-header {
      text-align: center;
      font-size: 15px;
      font-weight: 600;
      line-height: 19px !important;
      margin-bottom: 15px;
    }
  
    .sensitivity-table-item-full {
      width: 95%;
      text-align: center;
      font-size: 16px;
      padding-bottom: 5px;
    }
  
    .sensitivity-table-item {
      width: 95%;
      padding: 5px 0px;
      line-height: 18px;
    }
  
    .sensitivity-table-item span:last-child {
      padding-left: 20px;
    }
  
    .sensitivity-table-item.violet-txt span:last-child {
      padding-top: 7px;
    }
  
    .meta-chemo-efficacy .visit-btn {
      width: 330px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc p.tab-title.ffb-sb {
      font-size: 15px;
      line-height: 19px;
    }
  
    .pfs-hr, .os-hr {
      text-align: center;
      flex-direction: column;
    }
  
    .mos-text-block p {
      max-width: 250px;
      margin: 0 auto;
    }
    
      /*.meta-chemo-efficacy p.footnotes.wrap-notes{
          width: 102%;
      }*/
    
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .eyebrow {
      margin: 35px 0 15px 0;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2  ul.bullet-list.bullet-list-dash {
      padding: 20px 0 0px 5px;
    }
      /* graph sec2 mobile */
    
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar span {
      font-size: 34px;
      line-height: 24px;
      color: white;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 span.ffb-b-txt {
      font-size: 21px !important;
      top: -12px;
      position: relative;
      left: 10px;
      letter-spacing: 0.6px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 span.ffb-b-txt-2 {
      font-size: 9px !important;
      letter-spacing: 0.18px !important;
      font-weight: 400 !important;
      left: -65px;
      position: relative;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 p.tab-title.center-txt {
      display: none;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .bar-chart-horizontal {
      position: relative;
      left: 16px;
    }
  
    .section-2 p.tab-title.ffb-reg.center-txt {
      font-size: 14px;
      line-height: 18px!important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container {
      position: relative;
      max-width: 339px;
      margin: 0 auto;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-one {
      width: 255px;
      height: 74px;
      left: 57px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-two {
      width: 165px;
      height: 74px;
      left: 57px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-line {
      width: 100%;
      left: 57px;
      max-width: 260px;
      margin: 0;
      height: 188px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 ul.hor-scale {
      left: 6px;
      bottom: -23px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 ul.hor-scale {
   /*max-width:326px; margin:0 auto 20px; right:0;*/
      left: 16.2px;
      width: 93.4%;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .bar-chart-horizontal .hor-bar-one p {
      position: absolute;
      right: -48px;
      top: 25px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .bar-chart-horizontal .hor-bar-two.hor-bar p {
      top: 25px;
      right: -48px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data1,.meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data2 {
      font-size: 12px;
      line-height: 14px!important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data1 {
      left: -25px;
      bottom: 146px;
      text-align: right;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-ruler {
      width: 50.1px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 li.hor-ruler:nth-last-child(1) {
      width: 8px;
      right: 4px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-container .left-bar-data2 {
      bottom: 52px;
      left: -17px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-two.hor-bar {
      bottom: 25px;
      margin-bottom: 20px;
      transition: none;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-one.hor-bar {
      bottom: 119px;
      margin-bottom: 20px;
      transition: none;
    }
  
    ul.hor-scale {
      width: 100%;
      height: 14px;
      position: absolute;
      left: -7px;
      bottom: -6px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-one {
      min-width: 0;
      overflow: hidden;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-two {
      min-width: 0;
    }
    
      /* graph sec2 mobile end */
    
      /* circle sec2 mobile */
      
    .meta-chemo-efficacy .circles-wrapper {
      flex-direction: column;
      column-gap: unset;
      justify-content: normal;
      height: auto;
    }
  
    .meta-chemo-efficacy .circle-container {
      height: 310px;
    }
  
    .meta-chemo-efficacy p.circles-title {
      padding: 45px 0px 10px 0px;
    }
  
    #subgroups .footnotes {
      padding-left: 0;
    }
      
      /* circle sec2 mobile end*/
    
          /* tabs  mobile */
    
    .meta-chemo-efficacy.metastatic-nsclc .flaura-tabs-wrapper img {
      width: 100%;
      padding: 1px;
      margin: 0 0 20px 0;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc  .nav-pills>li {
      float: left;
      top: 1px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .nav-pills>li>a {
      top: 0;
      margin: 0;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .nav-pills>li.active>a, .meta-chemo-efficacy.metastatic-nsclc .nav-pills>li.active>a:focus, .meta-chemo-efficacy.metastatic-nsclc .nav-pills>li.active>a:hover {
      padding: 10px 25px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .nav-pills>li>a {
      padding: 10px 27px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .nav-pills>li.active>a, .meta-chemo-efficacy.metastatic-nsclc .section-6 .nav-pills>li.active>a:focus, .meta-chemo-efficacy.metastatic-nsclc .section-6 .nav-pills>li.active>a:hover {
      padding: 5px 3px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .nav-pills>li>a {
      padding: 5px 3.5px;
    }
    
      /* tabs  mobile end*/
    
      /*.meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper img {
        width: 100%;
        padding: 30px 0 10px 0;
    }
    
    .meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper img:last-child {
      padding: 10px;
    }*/
    
    .meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper .BarChart1 {
      /*background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/mobile/Secondary-endpoint-Bar-Chart-1-Mobile.png);*/
     /* background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/mobile/Secondary-endpoint-Bar-Chart-1-Mobile_v1.png);*/
      background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/mobile/Chart_1_Mobile.2X.png);
      background-repeat: no-repeat;
      width: 100%;
      background-size: 100%;
      max-width: 355px;
      height: 242px;
      margin: 30px auto 0 auto;
      position: relative;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper .BarChart2 {
      /*background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/mobile/Secondary-endpoint-Bar-Chart-2-Mobile.png);*/
     /* background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/mobile/Secondary-endpoint-Bar-Chart-2-Mobile_v1.png);*/
      background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/mobile/Chart_2_Mobile.2X.png);
      background-repeat: no-repeat;
      width: 100%;
      background-size: 100%;
      max-width: 355px;
      height: 308px;
      margin: 0 auto;
      position: relative;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper .BarChart1 p, .meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper .BarChart2 p {
      font: normal normal 700 16px/16px 'Barlow';
      color: #5B305D;
      position: absolute;
      top: 20px;
      text-align: center;
      margin: 0;
      left: 80px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper .BarChart2 p {
      font: normal normal 500 16px/16px 'Barlow';
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper .BarChart1 p span, .meta-chemo-efficacy.metastatic-nsclc .cns-responses-chemo-wrapper .BarChart2 p span {
      font: normal normal normal 12px/12px 'Barlow';
      color: #333;
      display: block;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc  .green-banner::after {
      content: " ";
      position: absolute;
      display: block;
      width: 100%;
      height: 100%;
      top: 0;
      left: 0px;
      z-index: -1;
      background: #008995;
      transform-origin: bottom;
      -ms-transform: skew(-20deg, 0deg);
      transform: skew(-8deg, 0deg);
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .green-banner {
      width: 92%;
      margin-bottom: 50px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc  .green-banner p.callout.is-visible.ffb-sb {
      padding-bottom: 10px;
      font-weight: 500 !important;
      padding-top: 5px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc  .green-banner::after {
      border-radius: 10px 20px 20px 6px;
    }
    
    /* vertical graph mobile */
    
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .hor-txt1 {
      position: absolute;
      bottom: -13px;
      left: 0px;
      font-size: 12px;
      width: 40%;
      font-weight: 700 !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .hor-txt1 span {
      font-weight: 400 !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6  .hor-txt2 {
      position: absolute;
      bottom: -1px;
      right: 35px;
      color: #46244C;
      font-size: 12px;
      width: 40%;
      font-weight: 400 !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 p.vertical-txt {
      position: absolute;
      top: -35px;
      bottom: 0;
      left: 7px;
      transform: rotate(270deg);
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6  .cns-progression-vertical-graph hr.ver-line {
      height: 195px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .is-visible .bar-one {
      min-height: 152px;
      width: 80px;
      background: #5B305D;
      left: 18px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-two.bar-container {
      background: #5B305D;
      width: 80px;
      min-height: 142px;
      left: 163px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6  span.ffb-med.nowrap.purple-txt.cfas-graph-a1 {
      line-height: 13px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 span.ffb-med.nowrap.cfas-graph-d1 {
      line-height: 13px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6  .bar.small-bar.bar-two {
      min-height: 60px;
      top: -20px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar.small-bar {
      top: -24px;
      width: 80px;
      height: 35px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph li.ruler {
      height: 49px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph li:first-child.ruler {
      margin-top: 67px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph ul.scale {
      top: -68px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph {
      max-width: 300px;
      margin: 0 auto;
      margin-bottom: 50px;
      left: 28px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .bar-graph1-copy {
      position: absolute;
      top: 24px;
      left: 105px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .bar-graph2-copy {
      position: absolute;
      left: 90px;
      top: -12px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt:nth-of-type(2) {
      position: absolute;
      top: -107px;
      left: 7px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6  p.ffb-b.purple-txt.cfas-graph-a {
      font-weight: 700 !important;
      margin-top: 35px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 p.tab-title.head-wrap.ffb-sb.meta-chemo-eff-vertical-graph-title {
      margin-bottom: 50px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .bottom-content {
      margin: 74px 0 0 0;
      text-align: center;
      line-height: 17px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6  .bottom-content.btm-content-2 {
      margin-top: 124px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt {
      position: absolute;
      top: -90px;
      left: 5px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph li.ruler:first-child p {
      margin-left: -17px;
    }
    
    /* vertical graph mobile end */
    .meta-chemo-efficacy.metastatic-nsclc .now-approved-art.mobile-only::after {
      content: "";
      display: block;
      width: 84%;
      top: 8px;
      left: 30px;
      height: 87px;
    /*background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/desktop/chemoApprovedPinkBrac.png);*/
      background-size: cover;
      margin-left: 0px;
      position: absolute;
      background-size: contain;
      background-repeat: no-repeat;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc  .section-2 .last-footnote {
      margin: 0px 0 30px 0;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-3 .eyebrow {
      margin: 45px 0 0 0;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc  h2.slide-to-top.unpre-median.first-line.is-visible {
      margin-bottom: 30px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-3 ul.bullet-list.align-after-panel-chemo {
      padding-top: 0px;
      margin-bottom: 10px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .tab-container {
      max-width: 706px;
      margin: 0 auto;
      padding: 0;
      border: 0;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc  .chemo-eff-spacer-30 {
      padding-bottom: 20px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc  .section-6  .eyebrow {
      padding-top: 40px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc h2.unpre-median.first-line.pfs-before-tabs-1 {
      width: 102%;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc h2.slide-to-top.unpre-median.first-line.pfs-before-tabs-2.is-visible {
      margin-bottom: 20px !important;
      margin-top: 10px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .bullet-list.chemo-eff-after-tabs {
      margin: 0px 0 70px 10px;
    }
    /*.meta-chemo-efficacy.metastatic-nsclc  .chemo-eff-spacer-20 {
    outline: 1px dashed red !important;
    fill: red !important;
    }*/
    .meta-chemo-efficacy .cns-response-table-wrapper {
      margin: 0 auto;
      max-width: 677px;
      padding-top: 20px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc  .chemo-eff-spacer-40 {
      padding-bottom: 20px;
    }
  
    h2.slide-to-top.unpre-median.before-control-arm.is-visible {
      margin-top: 30px;
      padding: 0 10px 0 0;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-9 .subhead {
      margin-top: -20px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .cycles-graphic-wrapper {
      padding-bottom: 10px;
      margin-top: -5px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-9 .eyebrow.chemo-spacer-top {
      padding-top: 50px;
      margin-bottom: -20px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc h2.slide-to-top.unpre-median.first-line.chemo-before-table.is-visible {
      padding-bottom: 10px;
      margin-top: 40px;
      padding-right: 10px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-9 .accordion.accordion-container.flaura-accordian.chemo-eff.horizontal {
      margin-top: -20px;
      margin-bottom: -10px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-9 .multi-column-container.meta-chemo-efficacy-internal-cta {
      padding: 40px;
      margin-top: -10px;
      margin-bottom: -10px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-9 .multi-column-container.meta-chemo-efficacy-internal-cta {
      padding: 40px 20px;
      margin-top: -10px;
      margin-bottom: -10px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-9 .multi-column-container.meta-chemo-efficacy-internal-cta .cta.r-cta {
      margin-bottom: 30px;
      margin-left: auto !important;
      margin-right: auto !important;
    }
  }
    
    /* ---------------------- chemotheraphy Efficacy page end styling*/
    
    
    /* Resesctable Efficacy page styling*/
  .efficacy {
      /*background:url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/eff-des.jpg) no-repeat;*/
      /*background-size:1366px 2271px;*/
      /*width:1366px;*/
      /*height:2271px;*/
    ;
  }
  
  .slide-frm-right {
    transform: translate(19em);
  }
  
  .bar-chart-horizontal sup {
    font-size: 60%;
  }
  
  .az-panel-title.panel-title {
      /*pointer-events: none;*/
    ;
  }
  
  .ml-2 {
    left: 2px;
  }
  
  .surgeon .font-b {
    font-weight: bold;
  }
  
  .efficacy .d-img-1 {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/New-Callout-Desktop.png) no-repeat;
    background-size: 100% 100%;
    width: 107px;
    height: 54px;
        /* position: relative; */
        /* left: -57px; */
        /* z-index: 99; */
        /* height: 55px; */
        /* position: relative; */
        /* top: 23px; */
        /* right: 56px; */
    z-index: 99;
    height: 54px;
    position: relative;
    top: 28px;
    right: 57px;
    left: -64px;
  }
    /*.efficacy .d-img-1::before{
           color: #FF00BA !important;
        content: "[";
        position: relative;
        font-size: 54px;
        left: -47px;
        top: 13px;
        font-family: system-ui !important;
        font-weight: 100 !important;
    }
    .efficacy .d-img-1::after{
            color: #FF00BA !important;
        content: "]";
        position: relative;
        font-size: 54px;
        right: -48px;
        top: 2px;
        font-family: system-ui !important;
        font-weight: 100 !important;
    }*/
    /*.efficacy .d-fl img::after{*/
    /*        color: #F527FF !important;*/
    /*    content: "]";*/
    /*    position: relative;*/
    /*    font-size: 72px;*/
    /*    right: -80px;*/
    /*    top: 12px;*/
    /*    font-family: system-ui !important;*/
    /*    font-weight: 100 !important;*/
    /*}*/
  #subgroups .az-panel-title.panel-title {
    pointer-events: auto;
  }
  
  .customTable .borderbtm0 td {
    border-bottom: 0 none;
  }
  
  .bordertop0 td {
    border-top: 0 none;
  }
  
  p.pill-txt {
    font-size: 10px;
    line-height: 12px;
  }
  
  .section-1 .eyebrow {
    margin: 35px 0 0 0;
  }
  
  .section-1 h1 {
    margin: 15px 0 27px 0;
  }
  
  .metastatic-nsclc .section-1 .num-bold.font-500 {
    font-weight: 500;
  }
  
  .section-1 .data-copy ,.section-1 .accordion.section,
    .pfs-hr, .os-hr {
    max-width: 711px;
    margin: 0 auto;
  }
  
  .pfs-hr, .os-hr {
    display: flex;
    align-items: center;
    justify-content: center;
    gap: 10px;
    margin-bottom: 25px;
  }
  
  .hr-heading {
    font-size: 63px;
    font-weight: bold;
    color: #5B305D;
    line-height: 45px !important;
    margin-bottom: 4px;
  }
  
  .hr-text {
    color: #5B305D;
    font-size: 16px;
    margin-top: 12px;
    margin-bottom: 1px;
    color: #333333;
    font-size: 14px;
  }
  
  .mos-text-block {
    text-align: center;
  }
  
  .mos-text-block p {
    font-size: 16px;
    color: #5B305D;
  }
  
  .mos-text-block hr {
    margin: 10px auto;
    width: 47%;
    border-top: 1px solid #9B9B9B;
  }
  
  .d-none {
    display: none;
  }
  
  .section-1 .accordion.section {
    margin: 0 auto 30px !important;
  }
  
  .section-1 .subhead {
    margin: 0 0 36px 0;
  }
  
  .section-1 .data-copy {
    border-top-left-radius: 20px;
    border-top-right-radius: 20px;
    overflow: hidden;
  }
  
  .copy-content {
    margin: 19px 0 15px 13px;
    transform: translate3d(100%, 0, 0);
  }
  
  .efficacy .no-display {
    display: none;
  }
  
  .copy-per {
    margin: 10px 0 0 0;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/shape-whitebg.png) no-repeat;
    transform: translate3d(0, -100%, 0);
    max-width: 138px;
    width: 100%;
    min-height: 97px;
    margin: 10px 0 0 40px;
  }
  
  .copy-per p {
    /*font: normal normal 800 63px/19px Barlow;*/
    padding: 20px 0 20px 9px;
    letter-spacing: -0.38px;
    font: normal normal 700 70px/19px Barlow;
    padding: 15px 0 0 0;
    margin-top: 6px;
  }
  
  .cns-progression-vertical-graph li.ruler:first-child p {
    margin-left: -17px;
  }
  
  .adaura-box {
    padding: 10px 56px 0 15px;
  }
  
  .efficacy .left-title, .efficacy .right-title {
    font-size: 15px;
    line-height: 19px!important;
    font-weight: 600;
    text-align: center;
  }
  
  .efficacy .sm-box-1, .efficacy .sm-box-2 {
    background: none;
  }
  
  .efficacy .sm-box-1 .ffb-sb, .efficacy .sm-box-2 .ffb-sb {
    padding-left: 8px;
  }
  
  .efficacy .sm-box-1 .ffb-sb li, .efficacy .sm-box-2 .ffb-sb li {
    font-size: 16px;
    line-height: 20px!important;
    color: #1A1818;
  }
    /*.copy-content-lg {*/
    /*    font-size: 28px !important;*/
    /*    line-height: 27px !important;*/
    /*}*/
  .demographic-table .purple-txt {
    color: #5B305D;
  }
  
  .copy-content-med {
    font-size: 23px;
    /*line-height: 27px;*/
    line-height: 22px;
  }
  
  .sm-content,.copy-content-med,.vs-txt {
    color: #333333;
  }
  
  .copy-content-sm {
    font-size: 14px;
    /*line-height: 27px;*/
    line-height: 24px;
  }
  
  .is-visible .copy-per, .is-visible .copy-content {
    transform: translate3d(0, 0, 0);
    transition: all 1.5s ease;
  }
  
  .section-1 .bullet-list,.section-15 .nccn-footnotes {
    margin: 0 auto;
    max-width: 500px !important;
    margin-left: auto !important;
  }
    /* ul.bullet-list.chemo-pfs-margin {
      width: 90%;
    } */
    
  .nccn-content {
    font-size: 16px;
    line-height: 20px !important;
    max-width: 541px;
  }
  
  #egfrm-bullet-fix {
    margin-bottom: -32px;
    margin-top: -37px;
  }
  
  #meta-eff-nccn-banner-fix-1 {
    width: 162px;
    position: relative;
    left: 5px;
  }
  
  .section-1 .nccn-block {
    margin: 25px 0 0 0;
  }
  
  .resectable-nsclc .copy-per p {
    font: normal normal 700 70px/19px Barlow;
    padding: 7px 0 0 0;
  }
  
  .section-2 .data-copy,.metastatic-nsclc .section-6 .data-copy {
    max-width: 714px;
    border-top-left-radius: 20px;
    border-top-right-radius: 20px;
    margin: 0 auto;
    /*border: 2px solid #9B9B9B;*/
    padding: 7px 0 8px 0;
  }
  
  .metastatic-nsclc .section-6 .data-copy {
    padding-top: 0;
  }
  
  .metastatic-nsclc .section-2 .data-copy, .metastatic-nsclc .section-6 .data-copy {
    border: 2px solid #9B9B9B;
    border-bottom: 0;
  }
  
  .metastatic-nsclc .section-9 .visit-btn a {
    padding: 9px 0;
  }
  
  .cns-progression-vertical-graph .bar-graph1-copy .purple-txt, .cns-progression-vertical-graph .bar-graph2-copy .purple-txt {
    text-align: center;
  }
  
  .top-content {
    text-align: center;
  }
  
  .metastatic-nsclc .section-1  .panel-body img {
    padding: 10px;
  }
  
  .section-2 .green-banner {
    margin: 40px 0 40px 0;
  }
  
  .section-2 .green-banner p {
    padding: 15px 0 15px 0;
  }
  
  .section-3 .last-footnote {
    margin: 0 0 35px 0;
  }
  
  .section-4 .eyebrow {
    margin: 55px 0 10px 0;
  }
  
  .section-4 h1 {
    margin: 0;
  }
  
  .efficacy.resectable-nsclc .text-4-1 sup {
    top: -0.47em;
  }
  
  .section-4 .subhead {
    /*margin: 20px 0 38px 0;*/
    margin: 30px 0px 25px 0px;
  }
  
  .section-4 .subhead2 {
    margin: 45px 0 25px 0;
  }
  
  .efficacy .semi-600 {
    font-weight: 600;
  }
  
  .efficacy .med-500 {
    font-weight: 500;
  }
  
  .section-4  .stage61-chart {
    display: flex;
    justify-content: center;
    align-items: center;
    margin-left: -70px;
  }
  
  .stage61-chart .footnotes {
    line-height: 27px !important;
    left: -3px;
    position: relative;
  }
  
  .stage61-chart .hr-txt {
    letter-spacing: 0.35px;
  }
  
  .section-4 .adj-table {
    margin: 0 auto !important;
    color: #333;
  }
  
  .section-4 .adj-table th {
    font-size: 17px;
    line-height: 22px;
    padding: 5px 43px;
    border-bottom: 4px solid #58305D;
  }
  
  .efficacy .refer-section.no-display {
    display: none;
  }
  
  .efficacy ul.median-list-5 li {
    font-size: 15px;
    line-height: 16px;
  }
  
  .efficacy #cns:before {
      /*box-shadow:0px 0 10px rgb(0 0 0 / 80%)!important;*/
    ;
  }
  
  .section-4 .rt-br {
    border-right: 1px solid;
  }
  
  .efficacy .no-bs:before, .efficacy .no-bs:after {
    box-shadow: none!important;
  }
  
  .efficacy .bs-title {
    font-size: 15px;
    line-height: 19px!important;
    margin-left: 63px;
    padding-top: 50px;
    margin-bottom: 20px;
  }
  
  #eff-mobile-chart-brain-title {
    font-weight: 600;
  }
  
  table#eff-table-height-fix-a {
    margin-bottom: 40px !important;
  }
  
  .efficacy .pb-60 {
    padding-bottom: 60px;
  }
  
  .section-4 .adj-table td {
    font-size: 16px;
    line-height: 33px;
    padding: 6px !important;
  }
  
  .section-4 .adj-table th:first-child {
    width: 238px;
    padding: 5px 5px 5px 25px;
  }
  
  .section-4 .adj-table .left-txt {
    text-align: left;
    padding: 5px 5px 5px 25px !important;
  }
  
  .section-4 .adj-table .left-txt {
    width: auto !important;
    border-bottom: none;
    font-size: 16px;
    line-height: 33px;
  }
  
  .section-4 .adj-table .last-data {
    border-bottom: 1px solid;
  }
  
  .section-4 .subhead3 {
    margin: 52px 0 20px 0;
  }
  
  .section-4 .stage-61-text {
    margin: 25px 0 0 0;
  }
  
  .section-4 .stage-61-text.copy-content-lg {
    font-size: 28px;
    line-height: 27px;
  }
  
  .section-4 .stage-61-text .txt-md {
    font-size: 23px;
  }
  
  .section-4  .stage-61-text .copy-content-sm {
    color: #333333;
  }
  
  .section-4 .new-image.table-text.graphic-image {
    width: 664px;
    margin: 0 auto;
  }
  
  .efficacy .pink-text.extrabold {
    font-weight: 900!important;
  }
  
  .section-5 .green-banner {
    margin: 57px 0 60px 0;
  }
  
  .section-5 .green-banner p {
    padding: 4px 0 6px 0;
  }
  
  .section-6 .last-footnote {
    margin: 0 0 76px 0;
  }
  
  .section-7 .eyebrow {
    margin: 55px 0 0 0;
  }
  
  .section-7 h1 {
    margin: 6px 0 0 0;
  }
  
  .section-7 .adaura-km-chart {
    margin: 55px 0 0 0;
  }
  
  .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-1 {
    max-width: 380px;
  }
  
  .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-2 {
    max-width: 384px;
    margin-left: 55px;
  }
  
  .section-7 .adaura-km-chart .column-1:after {
    content: "OR";
    position: absolute;
    right: -34px;
    top: 54px;
    color: #5B305A;
    font-family: 'Barlow';
    font-size: 22px;
    bottom: 0;
    margin: 0 auto;
    height: 31px;
    background: #fff;
    text-align: center;
    line-height: 26px;
    width: 31px;
    z-index: 99;
    font-weight: 800;
  }
  
  .adaura-km-chart .panel-heading.az-panel-heading {
    padding: 0;
  }
  
  .section-7 .adaura-km-chart .column-1:before {
    content: "";
    position: absolute;
    right: -20px;
    top: 5px;
    font-family: 'Barlow';
    width: 2px;
    bottom: 0;
    height: 136px;
    background: #9b9b9b;
    text-align: center;
  }
  
  .section-9 .last-footnote {
    margin: 0 0 35px 0;
  }
  
  .section-10 .eyebrow {
    margin: 55px 0 20px 0;
  }
  
  .section-10 h2 {
    margin: 0 0 42px 0;
  }
  
  .section-10 .lg-txt {
    font-size: 48px;
    float: left;
    width: 23%;
    height: 21px;
    padding: 10px 0 0 12px;
  }
  
  .efficacy .primary-button {
    padding: 10px 50px 8px 50px;
  }
  
  .section-10 .num-lg {
    font-size: 45px;
  }
  
  .section-10 .hor-bar p {
    font-size: 18px;
    line-height: 20px !important;
  }
  
  .section-10 .hor-bar-one p {
    position: absolute;
    right: -89px;
    top: 25px;
  }
  
  .section-10 .hor-bar-two.hor-bar p {
    top: 30px;
    position: absolute;
    right: -96px;
    color: #464749;
  }
  
  .hor-line {
    width: 460px;
    border-left: 1px solid #A0A0A0;
    border-bottom: 1px solid #A0A0A0;
    height: 267px;
    left: -45px;
    position: relative;
  }
  
  .cns-hor-bar .hor-line {
    left: 0;
  }
  
  ul.hor-scale {
    width: 78%;
    height: 14px;
    position: absolute;
    left: 94px;
    bottom: -23px;
  }
  
  .hor-ruler {
    border-left: 1px solid #A0A0A0;
    height: 5px;
    width: 16%;
    display: inline-block;
  }
  
  .bar-chart-horizontal {
    position: relative;
  }
  
  .hor-ruler p {
    position: absolute;
    top: 10px;
    left: -4px;
    font-size: 14px;
    line-height: 8px !important;
  }
  
  .hor-bar-container {
    position: relative;
  }
  
  .section-10 .hor-bar-container .left-bar-data1,.metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
    position: absolute;
    bottom: 230px;
    left: 42px;
  }
  
  .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
    bottom: 226px;
  }
  
  .metastatic-nsclc .hor-bar-one p,.metastatic-nsclc .hor-bar-two.hor-bar p {
    top: 37px;
  }
  
  .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
    bottom: 90px;
  }
  
  .metastatic-nsclc .section-9 .visit-btn {
    margin: 55px auto;
  }
  
  .metastatic-nsclc .section-1 .nccn-mob-content {
    height: 220px;
  }
  
  .section-10 .hor-bar-container .left-bar-data2 {
    position: absolute;
    bottom: 117px;
    font-size: 18px;
    left: 16px;
    color: #464749;
  }
  
  .section-10 .hor-line {
    width: 568px;
  }
  
  .section-10 ul.hor-scale {
    width: 81%;
    left: 126px;
    padding: 0;
  }
  
  .section-10 .hor-ruler {
    width: 12%;
    margin-right: 12px;
  }
  
  .section-10 .hor-bar-container .left-bar-data1 {
    position: absolute;
    left: 34px;
  }
  
  .section-10 .hor-bar-one {
    position: absolute;
    left: 127px;
    margin: 0 0 28px 0;
    transition: 1s all ease;
  }
  
  .section-10 .hor-bar-one,.metastatic-nsclc .section-6 .hor-bar-one {
    position: absolute;
    min-width: 0px;
    height: 92px;
    bottom: 186px;
    left: 134px;
    background: #5B305D;
    margin: 0 0 28px 0;
    transition: 1s all ease;
  }
  
  .metastatic-nsclc .section-6 .hor-bar-one {
    left: 135px;
  }
  
  .section-10 .is-visible .hor-bar-one.hor-bar {
    min-width: 50px;
  }
  
  .section-10 .hor-bar-two,.metastatic-nsclc .section-6 .hor-bar-two {
    position: absolute;
    min-width: 0px;
    height: 92px;
    bottom: 68px;
    left: 134px;
    background: #AEB0B3;
    margin: 0 0 32px 0;
    transition: 1s all ease;
  }
  
  .metastatic-nsclc .section-6 .hor-bar-two {
    left: 135px;
  }
  
  .section-10 .hor-bar-one,.section-10 .hor-bar-two {
    left: 127px !important;
  }
  
  .section-10 .is-visible .hor-bar-two {
    min-width: 475px;
  }
  
  img.patients {
    max-width: 568px;
    width: 100%;
  }
  
  .efficacy .m-top-zero {
    margin-top: 0!important;
  }
  
  .columnControl.section .column-1 .sm-callout {
    /*min-height: 139px;*/
    min-height: 90px;
  }
  
  .hor-bar p {
    font-size: 12px;
    line-height: 12px !important;
  }
  
  .hor-bar-one p {
    position: absolute;
    right: -59px;
    top: 32px;
  }
  
  .efficacy.resectable-nsclc .section-1 .copy-content {
      /*margin: 21px 0 20px 11px;*/
         /* margin: 21px 0 20px 11px; */
    margin: 21px 0 22px 11px;
    position: relative;
    top: 8px;
  }
  
  .metastatic-nsclc .hor-bar-one p {
    right: -52px;
  }
  
  .hor-bar-two.hor-bar p {
    top: 33px;
    position: absolute;
    right: -64px;
    color: #464749;
  }
  
  .metastatic-nsclc .hor-bar-two.hor-bar p {
    right: -65px;
  }
  
  .section-10 .bullet-list {
    margin: 22px 0 25px 7px;
  }
  
  .section-10 .bullet-list li {
    margin-bottom: 15px;
  }
  
  .section-10  .brain-section {
    display: flex;
    justify-content: center;
    position: relative;
    margin: 0 11px 65px 0;
  }
    /*.section-10 .brain-section:after {*/
    /*    content: "";*/
    /*    background: #5B305D;*/
    /*    position: absolute;*/
    /*    width: 60%;*/
    /*    height: 84%;*/
    /*    z-index: -1;*/
    /*    border-radius: 15px;*/
    /*    top: 11px;*/
    /*    left: 22%;*/
    /*    transform: skew(-25deg);*/
    /*}*/
  .section-10  .copy-txt {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/purple-slanted-shape.png);
    background-repeat: no-repeat;
    color: #fff;
    width: 100%;
    max-width: 482px;
    height: 94px;
    padding: 11px 0 0 43px;
    margin: 31px 0 0 -47px;
  }
  
  .section-10 .brain-icon-efficacy {
    z-index: 1;
  }
  
  .section-10  .img-small-txt {
    display: block;
    font-size: 14px;
    margin: 6px 0 0 12px;
  }
  
  .section-10 sup {
    font-size: 60%;
  }
  
  .section-10 .last-footnote {
    margin: 0 0 35px 0;
  }
  
  .section-11 h2.consistent-dfs {
    margin: 55px 0 42px 0;
  }
  
  .section-11 .sect-3 {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/eff-grey-arrow-block-shape.png) no-repeat;
    max-width: 234px;
    height: 138px;
    margin: 0 auto;
    padding: 10px 10px 10px 10px;
  }
  
  .section-11 .icons {
    display: flex;
    margin: 10px 0px 10px 0;
  }
  
  .section-11 .sect-3 p {
    font-size: 10px;
    line-height: 12px !important;
    margin: 0 0 0 10px;
    text-align: left;
  }
  
  .section-11 .adaura-chart-header {
    max-width: 242px;
    font-size: 12px;
    line-height: 16px !important;
    margin: 5px 0 -20px 142px;
    position: relative;
  }
  
  .section-11 .sect-3 b {
    font-size: 12.5px;
    line-height: 14px !important;
    margin: 0;
  }
  
  .section-11 .panel-body {
    padding: 20px;
  }
  
  .section-11 .sect-6 {
    display: flex;
    justify-content: space-around;
  }
  
  .section-11 .sect-7 {
    max-width: 211px;
    height: 118px;
    padding: 12px;
    margin: 10px auto 0;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/purple-block-shape.png)no-repeat;
  }
  
  .section-11 .sect-7 p {
    color: #fff;
    font-size: 15px;
    line-height: 22px !important;
    text-align: center;
    margin: 0;
  }
  
  .section-11 .sect-7 li {
    color: #fff;
    font-size: 12px;
    line-height: 14px !important;
    text-align: left;
  }
  
  .section-11 .sect-7 span {
    font-size: 22px;
    line-height: 22px;
  }
  
  .section-11 .subhead {
    margin: 32px 0 27px 0;
  }
  
  .section-11 .accordion.section .accordion-container .panel-default>.panel-heading+.panel-collapse>.panel-body span {
    color: #333;
  }
  
  .section-12 .green-banner {
    margin: 40px 0 40px 0;
  }
  
  .section-13 .nccn-block {
    margin: 30px auto;
    max-width: 708px;
  }
  
  .section-13 .bullet-list {
    margin: 0 0 35px 7px;
  }
  
  .section-13 h2.consistent-dfs {
    margin: 60px 0 0 0;
  }
  
  .section-13 table.demographic-table {
    max-width: 736px;
    margin: 0 auto !important;
    width: 95%;
  }
  
  .section-13 .eff-demographic-chart .panel-body, .section-14 .eff-demographic-chart .panel-body {
    padding: 15px 0 30px 0;
  }
    /*.section-13 td {*/
    /*    padding: 10px 50px 10px 50px !important;*/
    /*}*/
  .demographic-table th {
    font-size: 17px;
    line-height: 19px;
    color: #333;
  }
  
  table.demographic-table tr td:first-child, table.demographic-table tr th:first-child {
    padding-left: 15px !important;
    text-align: left;
  }
  
  table.demographic-table tr:nth-child(3) td:first-child, 
    table.demographic-table tr:nth-child(4) td:first-child, 
    table.demographic-table tr:nth-child(5) td:first-child,table.demographic-table tr:nth-child(7) td:first-child {
    padding-left: 40px !important;
  }
  #cns-data > div.page-section-inner.container > div:nth-child(4) > div > p{
    margin-bottom: 40px;
  }
  .section-13 td {
    padding: 10px 15px 10px 15px !important;
  }
  
  .section-13 .chart-body {
    text-align: center;
    padding: 10px 15px 5px 15px !important;
  }
  
  .chart-body-copy {
    font-size: 16px;
    padding: 0 65px 0 65px !important;
  }
  
  .section-13 th {
    padding: 10px 20px 4px 20px !important;
  }
  
  .section-13 td {
    border-bottom: 1px solid;
    border-left: 1px solid;
  }
  
  .section-13 td:nth-child(1) {
    border-left: none;
  }
  
  .section-13 .chart-body-copy {
    padding: 10px 0 10px 0!important;
    text-align: center;
  }
  
  .section-13 .chart-footnote {
    margin: 0 0 40px 56px;
    text-indent: 0;
  }
  
  .section-14  tr td:nth-child(1) {
    background: #f1f1f1;
  }
  
  p#eff-teal-banner-c {
    font-weight: 600 !important;
  }
  
  .callout.adaura-callout .green-banner p {
    padding: 10px 0 10px 0;
    font-weight: 600 !important;
  }
  
  .adaura-callout .green-banner {
    margin: 30px 0 65px 0;
  }
  
  .section-14 h2.consistent-dfs {
    margin: 55px 0 30px 0;
  }
  
  .section-14 .subhead {
    margin: 0 0 30px 0;
  }
  
  .section-14 .last-footnote {
    margin: 0 0 65px 0;
  }
  
  .section-14 .adaura-staging-table {
    max-width: 660px;
    margin: 0 auto  !important;
  }
  
  .section-14 .accordion.section .accordion-container .az-panel-title p {
    line-height: 19px !important;
  }
  
  .section-14 tr {
    text-align: left;
  }
  
  .section-14 th {
    text-align: center;
    padding: 0 25px 8px 37px;
    font-size: 16px;
    line-height: 17px;
  }
  
  .section-14 td {
    border: 1px solid;
    border-left: none;
    color: #333333;
    font-size: 16px;
    padding: 8px !important;
    line-height: 18px !important;
  }
  
  .section-14 td:nth-child(3) {
    border-right: none;
  }
  
  .adaura-callout .green-banner {
    margin: 30px 0 35px 0;
  }
  
  .section-15 h2.consistent-dfs {
    margin: 55px 0 25px 0;
    font-weight: 900;
    max-width: 766px;
  }
  
  .section-15 .nccn-block {
    margin: 0 auto;
    /*max-width: 708px;*/
    max-width: 720px;
  }
  
  .section-15 .nccn-content {
    font-size: 12.5px;
    line-height: 15px !important;
  }
  
  .section-15 .nccn-copy {
    display: block;
    margin-top: 5px;
  }
    
    /*.section-15 .nccn-lg.grey-bg:before {*/
    /*  height: 125px;*/
    /*}*/
  .section-15 .nccn-lg.grey-bg:before {
    height: 92px;
  }
  
  .section-15 .rtt-box {
    display: flex;
    align-items: flex-start;
    justify-content: space-around;
    max-width: 625px;
    margin: 45px auto;
  }
  
  span.icons {
    height: 102px;
    margin-bottom: 20px;
    display: flex;
    flex-direction: row;
    width: 100%;
    align-items: end;
      /* width: 100px; */
    ;
  }
  
  span.icons img {
    margin: 0 auto;
    display: block;
  }
  
  .efficacy.resectable-nsclc .txt-new {
    font-size: 12px;
    line-height: 15px!important;
    color: #333333;
  }
  
  .section-15 .rtt-section {
    width: 30%;
  }
  
  .rtt-content .subhead {
    line-height: 20px !important;
  }
  
  .section-15 .asco-copy {
    margin: 20px 0 20px 0;
  }
  
  .section-15 .last-footnote {
    margin: 0 0 25px 0;
  }
  
  .section-15 .visit-btn {
    /*max-width: 442px;*/
    max-width: 530px;
    margin: 50px auto 50px auto;
  }
    /* Metastatic efficacy page styling */
  .metastatic-nsclc  .copy-content-med {
    font-size: 18px;
    line-height: 22px;
  }
  
  .metastatic-nsclc .section-1 .eyebrow {
    margin: 34px 0 5px 0;
  }
  
  .metastatic-nsclc .section-1 h1 {
    margin: 0 0 20px 0;
  }
  
  .metastatic-nsclc .section-1 .subhead {
    margin: 0 0 42px 0;
  }
  
  .metastatic-nsclc .section-1 .copy-content-med {
    color: #5B305D !important;
  }
  
  .metastatic-efficacy .purple-txt {
    color: #5B305D;
  }
  
  .metastatic-nsclc .section-2 .copy-per {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/up-arrow-shape.png)no-repeat;
    margin: 20px 0 0;
    padding: 0 0 0 0;
    background-size: contain;
    width: 136px;
    min-height: 95px;
    height: 95px;
  }
  
  .metastatic-nsclc .section-1 .copy-per {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/whitebg-yr-shape.png) no-repeat;
    width: 20%;
    padding: 0;
  }
  
  .metastatic-nsclc .section-1 .hr-txt {
    font-size: 15px;
  }
  
  .metastatic-nsclc .section-1 .copy-content {
    margin: 23px 0 0 12px;
  }
  
  .metastatic-nsclc .section-1 .num-bold {
    font-size: 45px;
    position: relative;
    line-height: 54px;
    left: 8px;
    letter-spacing: -0.14px;
  }
  
  .metastatic-nsclc .section-1 .num-bold sup {
    font-size: 26px;
  }
  
  .metastatic-nsclc .section-1 .callout-box {
    display: flex;
    align-items: center;
    justify-content : center;
    padding-right: 40px;
  
  }
  /*10-11-2025*/
  .metastatic-nsclc .section-1 .callout-box sup {
      left: 2px;
      
  }
  
  .metastatic-nsclc .section-1 .callout-box p {
    padding: 0 0 0 20px;
    font-size: 17px;
    letter-spacing: -0.8px;
  }
  
  .metastatic-nsclc .section-1 .callout-box .vs-txt {
    font-size: 18px;
    line-height: 22px !important;
    letter-spacing: -0.07px;
    padding: 0 0 26px 20px;
  }
  
  #meta-ffb-txt-fix-align-1 {
    position: relative;
    left: -12px;
    top: 18px;
  }
  
  .align-center {
    text-align: center;
  }
  
  .metastatic-nsclc .section-1 .box-center {
    max-width: 467px;
    margin: 33px auto 42px;
    border: 2px solid #5B305D;
    border-left: none;
    border-right: none;
    padding: 10px 0 16px 0;
    padding-top: 0;
    margin-top: 10px;
  }
  
  .metastatic-nsclc .section-1 .box-center .subhead {
    margin: 15px 0 3px 0;
    /*margin: 0 0 0 0;*/
    margin-top: 10px;
    ;
  }
  
  .metastatic-nsclc .section-1 .nccn-footnotes {
    width: 75%;
    margin: 0 auto 50px auto;
    margin-left: 80px;
  }
  
  .metastatic-nsclc .section-1 .last-footnote {
    font-family: 'Barlow';
    margin: 0 0 54px 0;
    color: #333;
    line-height: 16px !important;
    font-size: 12px;
  }
  
  .metastatic-nsclc .section-1  .mn-nccn-content {
    background: #f1f1f1;
    padding: 20px 24px 14px 11px;
    /* height: 119px; */
  }
  
  .metastatic-nsclc .section-1 .nccn-content:before {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/leftcurve-grey.png) no-repeat;
    height: 110px;
    background-size: cover;
  }
  
  .m-head {
    font-size: 49px;
  }
  
  .m-nccn-sm {
    font-size: 23px;
  }
  
  .metastatic-nsclc .section-2 .eyebrow {
    margin: 55px 0 0 0;
  }
  
  .metastatic-nsclc .section-2 h1 {
    margin: 5px 0 0 0;
  }
  
  .metastatic-nsclc .section-2 .subhead {
    margin: 23px 0 40px 0;
  }
  
  .metastatic-nsclc .section-2  .copy-content {
    margin: 30px 0 25px 12px;
    width: auto;
  }
  
  .metastatic-nsclc .section-2 .lg-num {
    font-size: 69px;
    /*padding: 12px 4px 0 0;*/
    padding: 6px 4px 0 0 !important;
  }
  
  .metastatic-nsclc .section-2 .copy-content-md {
    font-size: 23px;
    line-height: 27px;
    color: #333333;
  }
  
  .metastatic-nsclc .section-2 .txt-med {
    font-size: 19px;
  }
  
  .metastatic-nsclc .section-2 .white-bold-txt {
    font-size: 40px;
    color: #fff;
  }
  
  .metastatic-nsclc .section-2 .pfs-block-img {
    width: 100%;
    max-width: 126px;
    height: 79px;
    margin: 0 9px 0 0;
    position: relative;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/purple-bg-shape.png)no-repeat;
  }
  
  .metastatic-nsclc .section-2 .pfs-center-block {
    display: flex;
    justify-content: center;
    align-items: center;
  }
  
  .metastatic-nsclc .section-2 .pfs-center-block.pfs-block1 {
    margin: 54px auto 0 auto;
  }
  
  .metastatic-nsclc .section-2 .pfs-orr {
    position: absolute;
    top: 25px;
    left: 17px;
  }
  
  .metastatic-nsclc .section-2 .pfs-median {
    position: absolute;
    left: 20px;
    top: 3px;
  }
  
  .metastatic-nsclc .section-2 .pfs-center-block.pfs-block2 {
    margin: 15px 0 50px 53px;
  }
  
  .metastatic-nsclc .section-2 .last-footnote {
    margin: 0 0 35px 0;
  }
  
  .metastatic-nsclc .section-3 .eyebrow {
    margin: 55px 0 0 0;
  }
  
  .metastatic-nsclc .section-3 .sectionA .eyebrow {
    margin: 35px 0 0 0;
  }
  
  .metastatic-nsclc .section-3 h2.pfs-before-tabs-1 {
    margin: 20px 0 10px 0;
  }
  
  .metastatic-nsclc .section-3 .subhead {
    margin: 25px 0 45px 0;
  }
  
  .metastatic-nsclc .section-4 .green-banner {
    margin: 40px 0 45px 0;
  }
  
  .metastatic-nsclc .section-5 .last-footnote {
    margin: 0 0 35px 0;
    text-indent: 0;
  }
  
  .metastatic-nsclc .section-6 h2 {
    margin: 55px 2px 20px 0;
  }
  
  .metastatic-nsclc.meta-chemo-efficacy .section-6 h2 {
    margin: 5px 2px 20px 0;
  }
  
  .metastatic-nsclc .section-6 .subhead1 {
    margin: 0 0 45px 0;
  }
  
  .metastatic-nsclc .section-6 .brain-icon {
    position: absolute;
    width: 82px;
    height: auto;
    top: -50px;
    background: #f1f1f1;
    left: 109px;
    z-index: 9;
  }
  
  .metastatic-nsclc .section-6 .graphic-subhead {
    background: #f1f1f1;
    left: 24px;
    top: -35px;
    width: 66%;
    padding-left: 66px;
  }
  
  .cns-block sup, .copy-per sup {
    font-size: 57%;
  }
  
  .metastatic-nsclc .section-6 .graphic-box {
    height: 181px;
    max-width: 714px;
    margin: 90px auto 75px auto;
  }
  
  .metastatic-nsclc .section-6 .cns-arrow-section {
    align-items: center;
    display: flex;
    justify-content: space-evenly;
    margin: 80px 0 0 0;
  }
  
  .metastatic-nsclc .section-6 .cns-block {
      /*background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/cns-arrow-shape.png);*/
    width: 174px;
    height: 74px;
    position: relative;
  }
  
  .metastatic-nsclc .section-6 .cns-block span {
    font-size: 48px;
    line-height: 58px;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/cns-arrow-shape.png) no-repeat;
    width: 174px;
    height: 74px;
    padding: 3px 46px 9px 22px;
    background-size: 100% 100%;
    left: 0;
    position: relative;
    transition: 1s all ease-out;
  }
  
  .metastatic-nsclc .section-6 .cns-block p {
    position: absolute;
    top: -40px;
    left: 40px;
    line-height: 26px !important;
    font-size: 22px;
  }
  
  .metastatic-nsclc .section-6 .cns-block1 {
    z-index: 9;
  }
  
  .metastatic-nsclc .section-6 .cns-block2 {
    z-index: 8;
  }
  
  .metastatic-nsclc .section-6 .cns-block3 {
    z-index: 7;
  }
  
  .metastatic-nsclc .section-6 .cns-block2 span {
    left: -168px;
  }
  
  .metastatic-nsclc .section-6 .cns-block3 span {
    left: -338px;
  }
  
  .metastatic-nsclc .section-6  .copy-content-sm {
    color: #333333;
  }
  
  .metastatic-nsclc .section-6 .is-visible .cns-block2 span, .metastatic-nsclc .section-6 .is-visible .cns-block3 span {
    left: 0;
  }
  
  .metastatic-nsclc .section-6 .subhead3 {
    margin: 0 0 40px 0;
  }
  
  .metastatic-nsclc .section-6 .bullet-list {
    margin: 65px 0 40px 10px;
  }
  
  .section-9  .verticalSlide  table.customTable {
    margin-top: 0px;
  }
  
  .hor-bar span {
    font-size: 41px;
    line-height: 16px;
      /*position: absolute;*/
      /*left: -64px;*/
      /*top: 10px;*/
    ;
  }
  
  .hor-bar-container .left-bar-data1 {
    bottom: 240px;
    font-size: 18px;
  }
  
  .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
    bottom: 93px;
    left: -17px;
    font-size: 18px;
  }
  
  .metastatic-nsclc .section-6 .last-footnote {
    margin: 0 0 60px 0;
  }
  
  .metastatic-nsclc .section-6 .subhead4 {
    margin: 60px 0 55px 0;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
    position: relative;
    max-width: 590px;
    margin: 0 auto 25px auto;
  }
  
  .metastatic-nsclc .section-6 .bar-chart-horizontal {
    position: relative;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph hr.ver-line {
    height: 375px;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph li:first-child.ruler {
    margin-top: -12px;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph li.ruler {
    height: 75px;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph ul.scale {
    top: 12px;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-one {
    position: absolute;
    width: 91px;
    min-height: 0px;
    bottom: 44px;
    left: 88px;
    background: #936693;
    transition: 1s all ease;
  }
  
  .metastatic-nsclc .section-6 .is-visible .bar-one {
    min-height: 228px;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar.small-bar {
    position: absolute;
    top: 0;
    background: #512C51;
    width: 91px;
    min-height: 0px;
    transition: 1s 1s all ease;
    opacity: 0;
    z-index: 0;
  }
  
  .metastatic-nsclc .section-6 .is-visible .bar.small-bar {
    min-height: 60px;
    top: -49px;
    opacity: 1;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt {
    position: absolute;
    top: -80px;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar p {
    font-size: 46px;
    line-height: 40px !important;
    /*margin: 8px 0 -8px;*/
    text-align: center;
    margin: 8px 0 -8px -10px;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar span {
    font-size: 14px;
    line-height: 16px !important;
  }
  
  .hor-txt2 {
    position: absolute;
    bottom: -14px;
    right: 130px;
  }
  
  .hor-txt1 {
    position: absolute;
    bottom: -15px;
    left: 97px;
  }
  
  .bar-graph1-copy {
    position: absolute;
    top: 86px;
    left: 190px;
  }
  
  .bar-graph1-copy span,.bar-graph2-copy span {
    font-size: 45px;
    color: #3B3C3E;
  }
  
  .bar-graph1-copy .bottom-content span,.bar-graph2-copy .bottom-content span {
    font-weight: 400 !important;
  }
  
  .bar-graph1-copy .purple-txt,.bar-graph2-copy .purple-txt {
    color: #5B305D;
  }
  
  .bottom-content {
    margin: 100px 0 0 0;
    text-align: center;
    line-height: 17px !important;
  }
  
  .top-content {
    line-height: 17px !important;
  }
  
  .bar-graph2-copy {
    position: absolute;
    left: 108px;
    top: 5px;
  }
  
  li.ruler:last-child {
    padding-left: 4px;
  }
  
  .is-visible .bar-graph2-copy {
    transform: none;
    text-align: center;
  }
  
  .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-two.bar-container {
    position: absolute;
    width: 91px;
    right: 150px;
    bottom: 45px;
    min-height: 0px;
    background: #A0A0A0;
    transition: 1s all ease;
  }
  
  .metastatic-nsclc .section-6 .is-visible .bar-two.bar-container {
    min-height: 243px;
  }
  
  .metastatic-nsclc .section-6  .hor-bar-container .left-bar-data2 {
    position: absolute;
    bottom: 85px;
    left: -18px;
    text-align: right;
    word-spacing: -4px;
  }
  
  .metastatic-nsclc .section-6 .hor-line {
    height: 282px;
  }
  
  .metastatic-nsclc .section-6 .hor-bar-two.hor-bar {
    min-width: 0px;
    bottom: 42px;
    transition: 1s all ease;
  }
  
  .metastatic-nsclc .section-6 .is-visible .hor-bar-two {
    min-width: 345px;
  }
  
  .metastatic-nsclc .section-6 .hor-bar-one.hor-bar {
    min-width: 0px;
    bottom: 167px;
    margin-bottom: 40px;
    transition: 1s all ease;
  }
  
  .metastatic-nsclc .section-6 .is-visible .hor-bar-one {
    min-width: 143px;
  }
  
  .metastatic-nsclc .section-6 .hor-ruler {
    width: 18.75%;
  }
  
  .metastatic-nsclc .section-6 .hor-ruler:first-child {
    left: 1px;
  }
  
  .metastatic-nsclc .section-7 .green-banner {
    margin: 40px 0 50px 0;
  }
  
  .metastatic-nsclc .section-8 .last-footnote {
    margin: 0 0 35px 2px;
  }
  
  .metastatic-nsclc .section-9 h2 {
    margin: 0 0 30px 0;
    padding: 0 20px 0 0;
  }
  
  .metastatic-nsclc .section-9 .small-txt {
    margin: 10px 0 30px 0;
  }
  
  .double-footnotes {
    text-indent: -5px;
    margin-left: 2px;
    padding-left: 0;
  }
  
  .flaura-section {
    display: flex;
    align-items: center;
    margin: 0 auto;
  }
  
  .block1 {
    border: 2px solid #0000004D;
    border-radius: 15px;
    width: 100%;
    max-width: 329px;
    padding: 15px 10px 10px 20px;
    margin: 0 40px 0 0;
  }
  
  .block1 ul {
    margin: 0 !important;
  }
  
  .block1 p,.block1 li {
    font-size: 14px;
    line-height: 16px !important;
  }
  
  .block1 .subhead {
    font-size: 16px;
  }
  
  .flaura-section .bullet-list {
    padding-left: 8px;
  }
  
  .flaura-section .bullet-list li:before {
    color: #3B3C3E;
  }
  
  .img1 {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/flaura-purple-shape.png) no-repeat;
    width: 260px;
    height: 70px;
    margin: 0 0 35px 0;
  }
  
  .img2 {
    height: 79px;
    padding: 8px 0 0 0;
    width: 262px;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/flaura-grey-shape.png) no-repeat;
  }
  
  .img2 p {
    font-size: 14.5px;
    line-height: 17px !important;
    margin: 0;
  }
  
  .img1 p {
    color: #fff;
    margin: 0 !important;
    padding: 15px 0 0 0;
    line-height: 18px !important;
  }
  
  p.ratio-lg {
    font-size: 46px;
    /*margin-left: 10px;*/
    ;
  }
  
  .block2 img {
    display: block;
    margin: 0 20px 30px 30px;
  }
  
  img.placebo {
    top: 14px;
    position: relative;
  }
  
  .flaura-section li,.heading2 {
    color: #3B3C3E;
  }
  
  .metastatic-nsclc .section-9 .accordion.section {
    margin: 50px auto -10px auto;
  }
  
  .metastatic-nsclc .section-9 .visit-btn {
    max-width: 456px;
    margin: 50px auto 40px auto;
  }
    
    /*.metastatic-nsclc .section-9 .customTable td:nth-child(1) {
    background: #f1f1f1;
    }*/
    
  div#dfs .panel-body {
    padding: 15px 15px 0px 15px;
  }
  
  div#sample-collapse1858997818 p.img {
    margin-bottom: -12px;
  }
  
  div#dfs img.desktop-only.az-lazyload.toggle-class {
    margin-top: -25px;
    margin-bottom: -19px;
  }
  
  h2.unpre-median,h2.consistent-dfs {
    font-weight: 800;
    font-size: 30px;
    line-height: 36px;
    color: #5B305D;
    margin-top: 5px;
  }
  
  .osi-adjuvant {
    width: 544px !important;
  }
  
  .n-number {
    font-family: 'Barlow';
    font-weight: 500;
  }
  
  .tag-heading-txt {
    font-weight: 700 !important;
  }
  
  .efficacy.resectable-nsclc .section-1 h2.new-data {
    color: #5B305D;
  }
  
  @media screen and (min-width: 992px) {
     .txt-alin{
    text-align:justify;
    padding:0 0 0 10px
}
    #isi > div.isi-container ul.subbul-gray li:not(:last-child){
      padding-bottom: 5px;
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-3 ul.bullet-list.meta-chemo-eff-after-egfr-table{
      margin-left: 6px !important;
    }
    #pfs > div.page-section-inner.container > div:nth-child(16) > div > div > div > p:nth-child(3){
    width: 143px;
  }
    #pfs > div.page-section-inner.container > div:nth-child(16) > div > div > div > p:nth-child(1){
      position: relative;
      right: 5px;
    }
    #efficacysubgroups > div.page-section-inner.container > div:nth-child(8) > div > ul{
      margin: 30px 0 20px 0;
    }
    #pfs > div.page-section-inner.container > div:nth-child(13) > div > h2{
      margin-bottom:50px!important;
    }
    #pfs > div.page-section-inner.container > div:nth-child(19) > div > p:nth-child(1){
        max-width: 783px;
    }
      #pfs > div.page-section-inner.container > div:nth-child(19) > div > .last-footnote{
    margin-top: 20px;
    }
  .first-line-footnote{
    margin-bottom:40px;
    /* padding-left: 58px; */
    max-width: 700px;
    margin-left: auto;
    margin-right: auto;
    white-space: nowrap;
  }
    body.fixed-top-margin.efficacy.metastatic-nsclc.metastatic-efficacy.meta-chemotherapy.meta-chemo-efficacy.default-fonts.dom-ready .green-banner {
      padding: 10px 21px 11px 90px;
      padding-left: calc((100% - 690px)/2);
      display: none;
    }
    
    .section-1 .bullet-list.pbl{
        max-width: 90% !important;
        padding-left: 13px;
    }
  
    #additional-results .orr-block {
      align-items: flex-start;
    }
  
    #additional-results ul.btm-list {
      margin-top: -61px;
      padding-left: 47px;
      max-width: 478px;
      width: 100%;
    }
  #additional-results ul.btm-list li{
    padding-bottom: 2px;
  }
    #cns-data .meta-chemo-efficacy.metastatic-nsclc .section-6 span.ffb-med.nowrap.purple-txt.cfas-graph-a1 {
      top: 0px;
    }
  
    .mb30 {
      margin-bottom: 30px !important;
    }
  
    .pt5 {
      padding-top: 5px !important;
    }
  
    p.tab-title.ffb-reg.center-txt {
      margin-top: -7px;
    }
  
    .mt-15 {
      margin-top: -15px;
    }
  
    .mr10 {
      margin-right: 10px;
    }
  
    .mr8 {
      margin-right: 8px;
    }
    
        /*****81422*******/
    
    .metastatic-nsclc.meta-chemo-efficacy .section-1 .mn-nccn-content {
      padding: 14px 22px 14px 11px;
    }
  
    .metastatic-nsclc.meta-chemo-efficacy .section-1 .copy-per {
      margin-top: 16px;
    }
  
    .meta-chemo-efficacy .sensitivity-table-container ul.bullet-list {
      text-align: left;
      margin-left: 70px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-3 ul.bullet-list.align-after-panel-chemo.forestPlotBullet {
      margin-left: 22px !important;
    }
  
    .dor-orr-block .btm-list+p {
      margin-top: 20px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar p {
      margin: 8px 0 -8px -15px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar span {
      left: -13px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 p.vertical-txt {
      top: -40px;
      left: 30px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-6 ul.chemo-eff-after-vertical-graph {
      margin-top: 0;
      margin-bottom: 10px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-3 .bullet-list.chemo-eff-after-tabs>li:last-child {
      margin-top: 10px;
    }
  
    #without-cns img {
          /*width: 699px;*/
          width: 100%;
          height: 333px;
          left: -22px;
          position: relative;
  
    }
    
     #without-cns img.no-left{
             left: 0px;
      scale: 1.03;
     }
    
    #without-cns img.scale {
      scale:1.1;
  
    }
        
      
       /*****81422*******/
  }
     /*****81422*******/
    
  .os-block {
    border: 2px solid #AFB0B3;
    border-radius: 10px;
    max-width: 720px;
    margin: 0 auto;
    position: relative;
    padding: 40px 80px 30px 80px;
  }
  
  .os-block .dosingTitle,.dor-orr-block .dosingTitle {
    font-size: 22px;
    color: #008995;
    line-height: 26px;
    background: #fff;
    padding: 0 10px;
    position: absolute;
    top: -15px;
    left: 210px;
  }
  
  .os-div,.dor-block,.orr-block {
    margin: 0px auto 20px;
    display: flex;
    justify-content: center;
    align-items: end;
  }
  
  .os-div p {
    margin: 0;
  }
  
  .os-div p.bold {
    font-size: 65px;
    color: #5B305D;
    line-height: 60px!important;
  }
  
  .os-div img {
    margin-right: 20px;
  }
  
  .os-block .btm-text {
    text-align: center;
    max-width: 600px;
    margin: 0 auto;
  }
  
  .dor-orr-block {
    border: 2px solid #AFB0B3;
    border-radius: 10px;
    max-width: 720px;
    margin: 0px auto 50px;
    position: relative;
    padding: 25px 70px 25px 80px;
  }
  
  .dor-block,.orr-block {
    justify-content: left;
    align-items: center;
  }
  
  .dor-block img,.orr-block img {
    margin-right: 8px;
  }
  
  /*21-05*/
  .efficacy .orr-block img{
      position: relative;
      /* top: 12px; */
  }
  /*21-05*/
  
  .dor-block p.bold,.orr-block p.bold {
    color: #5B305D;
  }
  
  .dor-orr-block p,.dor-orr-block ul {
    margin: 0;
    margin-bottom: 0!important;
  }
  
  .dor-orr-block .dosingTitle {
    left: 65px;
  }
  
  .dor-orr-block .btm-list {
    max-width: 380px;
    margin: -28px 0 0 101px;
  }
    
    
    
     /*****81422*******/
    
    
    
    /* Mobile styling*/
  @media screen and (max-width: 991px) {
      
      
    #pfs > div.page-section-inner.container > div:nth-child(16) > div > div > div > p:nth-child(3){
      width: 125px;
    }
    .EGFR-mutation-type-inner .EGFR-heading{
      max-width:fit-content !important;
      padding: 0 10px;
    }
    #efficacysubgroups > div.page-section-inner.container > div:nth-child(3) > div{
          padding: 0 6px 0 6px;
    }
   #efficacysubgroups > div.page-section-inner.container > div:nth-child(3) > div sup.rsup{
      top: -1px !important;!important
    }
    .pfs-sub-chart .expand-img-mobile {
       padding: 0 6px 0 1px;
    }
    #cns-data > div.page-section-inner.container > div:nth-child(5) > div > div > h2{
      margin: 20px 0 20px 0 !important;
    }
    .nccn-lockup-mob .nccn-head{
      position: relative;
      margin-bottom: 10px;
    }
     .nccn-lockup-mob .nccn-head>p{
      position: absolute;
      font-weight: 800;
      font-size: 16px;
      line-height: 18px;
      text-align: center;
      text-transform: uppercase;
      color: white;
      top: 35px;
      left: 50%;
      transform: translate(-50%, -50%);
      max-width : 200px;
      padding: 0 10px;
    }
    .new-footnotes-section{
    margin-bottom:50px !important;
  }
    p.bullet.interim-footnote{
    margin: 0 5px 10px 10px !important;
    position: relative;
  }
    p.bullet.interim-footnote:before{
      left: -2px !important;
    }
    .mob-only{
      display:block;
    }
    .metastatic-nsclc .section-1 .callout-box>.purple-txt {
      padding-left: 0px;
      max-width: 151px;
    }
    .meta-chemo-efficacy table.flaura2-demo-table td {
    line-height: 18px;
  
     letter-spacing: -0.2px;
    padding: 3px !important;
  }
  
  
    .wid-96p-glo {
      width: 96%;
    }
  
    .metastatic-efficacy  .purple-txt .text-nowrap {
      white-space: normal;
    }
  
    .flaura-tabs-wrapper.EGFR-mutation-type {
      margin: 37px 0 35px !important;
    }
  
    .metastatic-nsclc.meta-chemo-efficacy .section-6 h2.cns-chemo-head {
      margin-top: 50px;
    }
  
    .efficacy .b-le, .efficacy .b-re {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/callout-box-mobile.png) no-repeat!important;
      background-size: 100% 100%!important;
      width: 343px!important;
      height: 247px!important;
    }
  
    .efficacy .b-le .row-3 .footnote, .efficacy .b-le .row-4 .footnote {
      letter-spacing: 0;
    }
  
    .efficacy.resectable-nsclc .footnotes.nccn-footnotes.fn_2 {
      text-indent: -6px;
    }
  
    .efficacy .heading-block .line-3 {
      position: relative;
      margin-left: 0px;
    }
  
    .efficacy .nccn-bl-footnotes .footnotes {
      margin-left: 34px;
    }
  
    .efficacy.resectable-nsclc .section-1 .dfs-copy p.purple-txt.extrabold {
      text-align: center;
      font: normal bold 66px/16px Barlow !important;
      letter-spacing: -0.6px;
      color: #5B305D;
      /* padding-top: 19px !important; */
      display: flex;
      height: 100%;
      align-items: center;
      justify-content: center;
      position: relative;
      top: 2px!important;
    }
  
    .efficacy.resectable-nsclc .section-1 .copy-content {
      margin-left: 0px;
    }
     
     /*.efficacy .heading-block .line-3:before{*/
     /*       color: #FF00BA !important;*/
     /*   content: "[";*/
     /*   position: absolute;*/
     /*   font-size: 42px;*/
     /*   left: 10px;*/
     /*   z-index: 99;*/
     /*   top: 4px;*/
     /*   font-family: system-ui !important;*/
     /*   font-weight: 100 !important;*/
     /*}*/
     /* .efficacy .heading-block .line-3:after{*/
     /*       color: #FF00BA !important;*/
     /*   content: "]";*/
     /*   position: absolute;*/
     /*   font-size: 42px;*/
     /*   right: 12px;*/
     /*   top: 4px;*/
     /*   font-family: system-ui !important;*/
     /*   font-weight: 100 !important;*/
     /* }*/
    .efficacy .data-flex-box .data-flex-box-col {
      width: 343px!important;
      max-width: 100%!important;
    }
  
    .efficacy .user-s-1 {
      padding-left: 22px!important;
      padding-top: 16px!important;
      padding-bottom: 16px!important;
    }
  
    .efficacy .data-flex-box .data-flex-box-col, .efficacy .section-7 .adaura-km-chart {
      margin: 0 auto;
    }
  
    .efficacy .data-flex-box {
      margin: 20px -4px 15px!important;
    }
  
    .efficacy .d-m-img-2 {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/New-img-Mobile.png) no-repeat;
      background-size: 100% 100%;
      width: 87px;
      height: 42px;
        /* position: relative; */
        /* left: -57px; */
        /* z-index: 99; */
        /* height: 55px; */
        /* position: relative; */
        /* top: 23px; */
        /* right: 56px; */
      z-index: 99;
        /* height: 54px; */
      position: relative;
      top: 28px;
      right: 48px;
    }
    /*.efficacy .d-m-img-2::before{
            color: #FF00BA !important;
        content: "[";
        position: relative;
        font-size: 50px;
        left: -34px;
        top: 7px;
        font-family: system-ui !important;
        font-weight: 100 !important;
    }
    .efficacy .d-m-img-2::after{
            color: #FF00BA !important;
        content: "]";
        position: relative;
        font-size: 50px;
        right: -34px;
        top: 2px;
        font-family: system-ui !important;
        font-weight: 100 !important;
    }*/
    .efficacy.resectable-nsclc .section-1 h1.new-data {
      font-size: min(8.7vw,36px);
      margin-bottom: 0;
    }
  
    #cns .final-analysis-link, #subgroups .final-analysis-link {
      padding-top: 25px;
    }
  
    .efficacy.resectable-nsclc .section-1 h2.egfr-mutation.new-datatwo {
      font-size: min(4.6vw,17.5px);
    }
  
    .green-banner p.callout.is-visible.ffb-sb {
      padding-bottom: 4px;
    }
    
    /* updates */
    
    
    
    .efficacy.resectable-nsclc .section-13 .patient-img.tab-title img {
      height: 100% !important;
      /*width: 370px !important;*/
      ;
    }
  
    .is-visible .green-banner {
      transform: revert !important;
    }
  
    .efficacy .d-fl img.mobile-only {
      left: -47px;
      top: 26px;
      height: 45px;
    }
  
    #eff-mobile-margin-prior-per {
      position: relative;
      top: 10px;
      padding-top: 15px;
    }
  
    #eff-mobile-chart-brain-title {
      margin-left: 0;
      text-align: center;
      font-weight: 600;
      margin-top: -40px;
    }
  
    .efficacy.resectable-nsclc .section-1 .dfs-copy p.purple-txt.extrabold {
      padding-bottom: 30px !important;
    }
  
    #eff-resec-target-banner-mobile-margin {
      margin-left: 0;
      margin-top: 20px;
    }
  
    #eff-boxes-fix-stat-copy-fix-b1 {
      position: relative;
      top: 12px;
      font-size: 13px;
      margin-top: 2px !important;
      margin-bottom: 2px !important;
      letter-spacing: -0.42px !important;
    }
  
    #eff-boxes-fix-stat-copy-fix-b2 {
      position: relative;
      top: 17px;
      line-height: 14px !important;
    }
  
    #eff-boxes-fixes-dfs-copy-a1 {
      position: relative;
      top: 12px;
      font-size: 13px !important;
      line-height: 15px !important;
    }
  
    .efficacy .text-6 {
      font-weight: 700 !important;
    }
  
    p.text-6-1 {
      position: relative;
      top: 2px;
    }
  
    #eff-boxes-fixes-dfs-copy-a2 {
      padding: 0px 20px;
      position: relative;
      top: 1px;
      max-width: 339px;
    }
  
    #eff-boxes-fixes-dfs-copy-a3 {
      font-size: 13px !important;
      line-height: 15px !important;
      position: relative;
      top: 6px;
    }
  
    #eff-boxes-fix-spacer {
      padding: 10px 0px;
      position: relative;
      top: 8px;
      left: 10px;
    }
  
    p.or-txt:after {
      bottom: 120px !important;
    }
  
    span#efficacy-mob-brain-copy-fix-a {
      font-weight: 500 !important;
    }
  
    span#efficacy-mob-brain-copy-fix-b {
      font-weight: 600 !important;
      font-size: 14px;
    }
  
    span#efficacy-mob-brain-copy-fix-c {
      font-weight: 200 !important;
      font-size: 14px;
    }
  
    .efficacy.resectable-nsclc .section-10 .brain-section {
      padding-bottom: 20px;
    }
  
    .efficacy.resectable-nsclc .section-5 .green-banner {
      margin: 25px 0 41px 0 !important;
    }
  
    .efficacy.resectable-nsclc .section-4 .subhead3 {
      margin: 48px 0 22px 0px !important;
      font-size: 22px;
    }
  
    #efficacy-graph-title-fix-00 {
      padding: 11px 0 11px 14px;
      text-align: left;
    }
  
    #graph-efficacy-title-fix-01 {
      display: block;
    }
  
    .efficacy.resectable-nsclc .section-15 .box-2 .treat-dna-icon {
      width: 96px !important;
      height: auto !important;
      position: relative;
      top: -9px;
    }
  
    p#eff-margin-rethink-a {
      margin-top: 0px;
    }
  
    .efficacy ul.median-list-5 {
      margin-bottom: 20px !important;
      padding-top: 20px;
    }
  
    #eff-extxt-fix {
      position: relative;
      top: -8px;
    }
  
    #graph-eff-height-a {
      height: 100px;
    }
  
    #eff-ex-txt-fix-a {
      font-size: 30px;
    }
  
    #eff-ex-txt-fix-b {
      font-size: 15px;
      font-weight: 600;
    }
  
    #eff-ex-txt-fix-c {
      font-weight: 400;
    }
  
    #eff-ex-txt-fix-d {
      font-weight: 400;
      position: relative;
      left: -34px;
      font-size: 15px;
    }
  
    #graph-eff-height-b {
      max-width: 300px;
    }
    
    /*updates end */
    
    .metastatic-nsclc .section-6 .bar-chart-horizontal {
      position: relative;
      left: 13px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
      left: 10px;
    }
  
    .efficacy .heading-block .line-1 {
      font: normal normal 14px/15px Barlow!important;
    }
  
    .efficacy .heading-block .line-2 {
      font: normal normal 800 28px/23px Barlow!important;
      letter-spacing: -0.5px!important;
    }
  
    .efficacy .heading-block .line-3 {
      font: normal normal 17px/19px Barlow!important;
      margin-left: 0px!important;
    }
  
    .efficacy .yellow-box {
      width: 336px!important;
      height: 112px!important;
      /* margin-left: 0; */
      margin: 10px auto!important;
      max-width: 100%!important;
    }
  
    .efficacy .data-flex-box {
      flex-direction: column!important;
      /* margin: 0 auto; */
      justify-content: center!important;
    }
  
    .efficacy .data-flex-box .data-flex-box-col {
          /*  width: 332px!important;*/
      /* height: 235px; */
      ;
    }
  
    .efficacy .data-flex-box .green-text-line-1 {
            /* font: normal normal 800 29px/17px Barlow; */
      /* color: #0E8995; */
      font: normal normal 800 29px/17px Barlow!important;
      color: #0E8995!important;
    }
  
    .efficacy .data-flex-box .green-text-line-2 {
            /* font: normal normal 500 14px/17px Barlow; */
      /* color: #0E8995; */
      /* margin: 5px 0px; */
      font: normal normal 500 14px/17px Barlow!important;
      color: #0E8995!important;
      margin: 8px 0px 8px 0px!important;
    }
  
    .efficacy .text-5 {
      padding-top: 0!important;
    }
  
    .efficacy .b-le .row-2 {
            /* padding-top: 11px; */
      padding-top: 8px!important;
    }
  
    .efficacy .data-flex-box p {
      margin: 0!important;
    }
  
    .efficacy .b-le .row-3 {
            /* max-width: 358px; */
      /* margin-left: 18px; */
      /* margin-right: 10px; */
      /* max-width: 349px; */
      /* margin: 0 auto; */
      /* max-width: 358px; */
      /* margin-left: 18px; */
      /* margin-right: 10px; */
      max-width: 349px!important;
      margin: 0 auto!important;
      margin-top: 8px!important;
    }
  
    .efficacy .b-le .row-3 .footnote, .efficacy .b-le .row-4 .footnote {
            /* font: normal normal normal 12px/16px Barlow; */
      font: normal normal normal 13px/15px Barlow!important;
      color: #606060!important;
      text-align: center!important;
    }
  
    .efficacy .data-flex-box .data-flex-box-col {
           /* width: 332px!important;*/
      /* height: 235px; */
      /*margin-top: 80px!important;*/
      /* max-width: 100%; */
      /* margin: 0 auto; */
      ;
    }
  
    .efficacy .d-fl {
      display: flex!important;
      justify-content: center!important;
      margin-bottom: -3px!important;
    }
  
    .efficacy ul.median-list {
      margin-top: 0px!important;
    }
  
    .efficacy .brd-btm hr {
      width: 250px!important;
      margin: 30px auto 0px !important;
    }
  
    .efficacy .data-flex-box .data-flex-box-col:nth-child(2) .above-card-wrap .barlow-bold {
      position: relative!important;
      /* left: -44px; */
      left: -58px!important;
      top: 1px!important;
    }
  
    .efficacy .above-card-wrap .font-style {
      display: block!important;
      font-weight: 500!important;
      line-height: 17px!important;
      font-size: 14px!important;
      margin-top: 1px!important;
      /* margin-left: -79px; */
      position: relative!important;
      left: -58px!important;
      margin-bottom: 6px!important;
    }
  
    .efficacy.resectable-nsclc .section-1 .km-curve {
      text-align: center!important;
      position: relative!important;
      max-width: 100%!important;
      height: auto!important;
      width: auto!important;
    }
  
    .efficacy.resectable-nsclc .section-4 .new-image.table-text.graphic-image {
      text-align: center!important;
      position: relative!important;
      max-width: 100%!important;
      height: auto!important;
      width: auto!important;
      top: -8px;
    }
  
    .efficacy .desktop-only-1 {
      display: none;
    }
    /* ended */
    
    .metastatic-nsclc .section-1  .panel-body img {
      padding: 10px 10px 0px 10px;
      position: relative;
      bottom: 8px;
    }
  
    #pfs .copy-content {
     margin: 10px 5px 20px !important;
    }
    .metastatic-nsclc .section-6 .data-copy .copy-content {
      
      margin: 10px 10px 0;
  }
        .metastatic-nsclc .section-6 .data-copy .copy-content{
      margin-top: 10px!important;
    }
  #without-cns .panel-body {
      padding: 15px 3px;
  }
    .metastatic-nsclc .section-6 .data-copy .copy-content.no-tsp {
      margin-top: 0px;
    }
    /*#pfs .newImage{*/
    /*    bottom:10px;*/
    /*}*/
    #egfrm-bullet-fix {
      margin-top: revert;
    }
  
    .met-eff-img-fix1 {
      margin-bottom: 15px;
    }
    
    /*.section-1 .nccn-block-mob {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/nccn-callout-mob.png) no-repeat center 1px;
    }*/
    
    .section-2 .green-banner p.callout.is-visible.ffb-sb {
      padding-bottom: 15px;
    }
  
    .metastatic-nsclc .section-2 .lg-num {
      padding-top: 1px;
    }
  
    .section-2 .copy-per p {
      margin-top: 5px;
    }
  
    div#staging.section-14 table.adaura-staging-table {
      width: 95%;
    }
  
    span.diff-block {
      display: block;
      padding-top: 3px;
    }
  
    img.az-80-pill-bottle {
      padding-bottom: 5px;
    }
  
    .metastatic-nsclc .section-9 .visit-btn a {
      padding: 9px 0;
      padding-right: 36px;
      padding-left: 21px;
      padding-top: 8px;
    }
  
    .section-6 p.tab-title.ffb-reg.center-txt {
      font-size: 14px;
      line-height: 18px !important;
    }
  
    img.placebo {
      padding-bottom: 5px;
    }
  
    .metastatic-nsclc #os .panel-body img {
      width: auto;
      max-width: 375px;
      margin-left: 0px;
    }
  
    .metastatic-nsclc .cns-pfs-chart img {
      /*margin-top: 0px;*/
      margin: 0 auto;
    }
  
    .metastatic-nsclc #subgroups .panel-body img {
      margin-left: 0px;
    }
  
    .metastatic-nsclc .brain-img-section {
      left: -11px;
      position: relative;
    }
  
    div#subgroups .panel-body img {
      width: auto !important;
      max-width: 100%;
      margin-left: -3px;
      padding: 0 10px;
    }
  
    .efficacy.resectable-nsclc.resect-efficacy div#subgroups .panel-body img {
      margin-left: 0;
      padding: 0 15px;
    }
  
    div#subgroups .panel-body {
      padding: 15px 5px;
    }
  
    .slide-frm-right {
      transform: none;
    }
  
    .section-1 .eyebrow {
      margin: 35px 0 0 0;
    }
  
    p.ratio-lg {
      margin-left: 0px;
      text-align: center;
    }
  
    .section-1 h1 {
      margin: 5px 0 20px 0;
    }
  
    .copy-per {
      margin: 12px 0 0 0;
      max-width: 115px;
      height: 80px;
      background-size: contain;
      padding: 0;
      min-height: 80px;
    }
  
    .section-6 .copy-per {
      padding-top: 5px;
    }
  
    .section-1 .subhead {
      margin: 0 0 25px 0;
    }
  
    .is-visible .copy-per, .is-visible .copy-content {
      transform: none;
      transition: none;
    }
  
    .copy-content {
      margin: 0px;
    }
  
    .copy-content-lg {
      font-size: 28px;
      line-height: 28px;
    }
    .cns-call .chemo-chart-txt-med{
      padding:5px 20px 0 20px;
    }
    .accordion.section .accordion-container .az-panel-title p {
      /*padding: 12px 24px 12px 15px;*/
      padding: 10px 24px 12px 15px;
    }
  
    .accordion-container .collapse-panel-heading .fa {
      right: 10px;
      top: 14px;
    }
  
    .nccn-content-mob {
      font-size: 16px;
      line-height: 20px !important;
    }
  
    .section-1 .bullet-list {
      width: 100%;
      margin: 0 0px 0 20px !important;
      padding-right: 27px;
    }
  
    .section-1 .nccn-content-mob {
      background-color: #f1f1f1;
      padding: 15px 16px 20px;
    }
  
    .section-1  .accordion-container .collapse-panel-heading .fa {
      top: 20px;
    }
  
    .section-4 .adj-table th {
      padding: 5px 8px;
    }
  
    .section-4 .adj-table td {
      padding: 5px;
    }
  
    .section-2 .green-banner {
      margin: 20px 0 20px 0;
      width: 85%;
      padding: 0px 0px 0px 38px;
    }
  
    .section-4 .eyebrow {
      margin: 55px 0 20px 0;
    }
  
    .section-4 .subhead {
      margin: 20px 0 28px 0;
    }
  
    .section-4 .subhead2 {
      margin: 49px 0 22px 0;
    }
  
    .section-4 .accordion.section .accordion-container .az-panel-title p {
      padding: 8px 38px 8px 15px;
    }
  
    .section-4 .adj-table {
      margin: 15px auto 40px auto !important;
    }
  
    .stage61-chart p.footnotes.purple-txt.ffb-sb.txt-ctr {
      text-indent: 0px;
      left: 0px;
    }
  
    .percentage-bar-text {
      margin-top: -20px;
      font-size: 11px;
    }
  
    .section-10 .bullet-list {
      margin-top: 15px;
    }
  
    .section-4 .stage61-chart {
      flex-direction: column;
    }
  
    .section-4 .stage-61-text {
      margin: 5px 10px 0 0;
      transform: none;
      text-align: center;
    }
  
    .section-4 .new-image.table-text.graphic-image {
      width: inherit;
      margin: 0px;
    }
  
    .section-5 .green-banner {
      margin: 28px 0 25px 0;
      width: 82%;
      padding: 12px 0px 12px 38px;
    }
  
    .section-6 .last-footnote {
      margin: 0 0 35px 0;
    }
  
    p.or-txt {
      text-align: center;
      color: #5B305A;
      font-family: 'Barlow';
      font-size: 22px;
      font-weight: 800;
      width: 45px;
      margin: 10px auto;
      background: #fff;
      z-index: 1;
    }
  
    p.or-txt:after {
      content: "";
      position: absolute;
      width: 94%;
      height: 2px;
      background: #9b9b9b;
      left: 9px;
      bottom: 9px;
      z-index: -1;
    }
  
    .efficacy.resectable-nsclc .section-7 .adaura-km-chart p.or-txt {
      background: #f1f1f1;
    }
  
    .metastatic-nsclc .section-2 .copy-content-md {
      margin-bottom: 2px !important;
      display: inline-block;
    }
  
    .section-7 .adaura-km-chart .column-1:after,.section-7 .adaura-km-chart .column-1:before {
      display: none;
    }
  
    .adaura-box {
      padding: 10px 45px 10px 12px;
    }
  
    .column-1 .adaura-box {
      padding-bottom: 10px;
    }
  
    .adaura-sm {
      font-size: 12px;
      line-height: 8px !important;
      padding: 0 0 10px 12px;
    }
  
    .adaura-copy {
      padding-right: 15px;
    }
  
    .section-7 .eyebrow {
      margin: 55px 0 0 0;
    }
  
    .section-7 .adaura-km-chart {
      max-width: 376px;
      margin: 35px auto 0 auto;
    }
  
    .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-2 {
      margin-left: 0;
      padding-right: 0;
    }
  
    .section-7 .columnControl.section .column-2 {
      padding-left: 0;
    }
  
    .section-7 .columnControl.section .column-1 {
      padding-right: 0;
    }
  
    .section-10 .eyebrow {
      margin: 55px 0 20px 0;
    }
  
    .section-10 h1 {
      margin: 0 0 26px 0;
    }
  
    .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data1,
    .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data2 {
      font-size: 11px;
      line-height: 14px !important;
    }
  
    .resectable-nsclc .section-10  .hor-line {
      width: 258px;
      height: 267px;
    }
  
    .resectable-nsclc .section-10 .hor-bar-container .left-bar-data2 {
      left: -45px;
      text-align: right;
    }
  
    .resectable-nsclc .section-10 .hor-bar-container .left-bar-data1 {
      left: -56px;
    }
  
    .resectable-nsclc .section-10 .bar-chart-horizontal {
      position: relative;
      max-width: 253px;
      margin: 0 auto;
    }
  
    .resectable-nsclc .section-10 .hor-bar-one {
      min-width: 24px !important;
      left: 0;
      margin-bottom: 17px;
    }
  
    .resectable-nsclc .section-10 ul.hor-scale {
      left: 0;
      bottom: 23px;
      padding: 0;
      width: 359px;
    }
  
    .resectable-nsclc .section-10 .hor-ruler {
      width: 9.8%;
      margin-right: 5px;
    }
  
    .resectable-nsclc .section-10 .hor-bar-two {
      min-width: 212px;
      left: 0;
      margin-bottom: 20px;
    }
    /*.resectable-nsclc .section-10 ul.hor-scale {*/
    /*    left: 126px;*/
    /*    bottom: 22px;*/
    /*}*/
    /*.resectable-nsclc .section-10 .hor-ruler {*/
    /*    width: 8%;*/
    /*}*/
    .resectable-nsclc .section-10 .hor-bar-container {
      position: relative;
      max-width: 339px;
      margin: 0 auto;
    }
    /*.resectable-nsclc .section-10 .hor-bar-container .left-bar-data2 {*/
     
    /*}*/
    .copy-per p {
      font: normal normal 700 62px/19px Barlow !important;
      padding: 24px 0 20px 0;
      letter-spacing: -0.38px;
      line-height: 74px !important;
      margin: 0 !important;
      padding: 0 !important;
    }
  
    .resectable-nsclc .copy-per p {
      margin-top: 15px;
    }
  
    .metastatic-nsclc .section-6 .data-copy .copy-per p {
      padding: 22px 0 24px 0;
      line-height: 60px !important;
    }
  
    .section-10 .brain-section {
      display: block;
      max-width: 302px;
      margin: 45px auto 55px auto;
    }
  
    .section-10 .hor-bar-one, .section-10 .hor-bar-two {
      left: 0 !important;
    }
  
    .section-10 .brain-icon-efficacy-mob {
      position: relative;
      top: -37px;
      left: 22px;
    }
  
    .section-10 .brain-img-txt {
      position: absolute;
      top: 21px;
      color: #fff;
      left: 26px;
      padding: 0;
    }
  
    .section-10 .img-small-txt {
      margin: 0px 5px 0 0;
    }
  
    .section-10 .brain-section:after {
      content: "";
      background: #5B305D;
      position: absolute;
      width: 90%;
      height: 141px;
      z-index: -1;
      border-radius: 15px;
      top: 2px;
      left: 15px;
      /*transform: skew(-25deg);*/
      transform: skew(-15deg);
    }
  
    .section-10 .lg-num {
      padding-left: 24px;
      font-size: 46px;
    }
  
    .section-10 .copy-txt {
      background: none;
    }
  
    .section-10.btm-shadow span.ffb-b.cns-text {
      display: block;
      padding-top: 2px;
    }
  
    .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-1 .accordion.section .accordion-container .az-panel-title p {
      padding: 9px 24px 9px 15px;
    }
  
    .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-2 .accordion-container .collapse-panel-heading .fa {
      top: 8px;
    }
  
    .small-txt {
      font-size: 9px;
      line-height: 12px !important;
    }
  
    .hor-ruler p {
      position: absolute;
      top: 10px;
      left: -4px;
      font-size: 11px;
      color: #262626;
      line-height: 7.58px !important;
    }
  
    .hor-bar b {
      font-size: 12px;
      font-weight: inherit;
    }
  
    .section-10 .hor-bar-one p {
      position: absolute;
      right: -60px;
    }
  
    .section-10 .hor-bar-two.hor-bar p {
      right: -64px;
    }
  
    .sect-1.txt-ctr img {
      max-width: 115px;
      height: 129px;
    }
  
    .text.parbase ul.box-unaccept {
      margin-top: 4px;
    }
  
    .text.parbase ul.box-unaccept {
      margin-top: 4px;
      padding-left: 6px;
    }
  
    ul.box-unaccept li:before {
      background: #fff;
      content: "";
      width: 3px;
      height: 3px;
      position: absolute;
      left: -8px;
      top: 7px;
      border-radius: 50%;
    }
  
    ul.box-unaccept li {
      position: relative;
      list-style: none;
      display: block;
      margin: 0;
      line-height: 14px;
      max-width: 113px;
      margin: 0 auto;
      text-align: center;
    }
  
    table.demographic-table tr:nth-child(10) td:first-child, table.demographic-table tr:nth-child(13) td:first-child {
      line-height: 18px;
    }
  
    .box-3 span.icons img {
      padding-left: 6px;
    }
  
    span.icons img {
      margin-bottom: -3px;
    }
  
    .resectable-nsclc .section-11 .left-img .az-80-pill-bottle {
      position: relative;
      top: 1px !important;
      right: -15px !important;
      width: 60px;
      height: 65px;
    }
  
    .section-11 .left-img p,.section-11 .right-img p {
      font-size: 14px;
      line-height: 15px !important;
    }
  
    .section-11 .img-head {
      font-size: 12px;
      line-height: 16px !important;
      width: 72%;
      margin: 0 auto;
      padding-bottom: 10px;
    }
  
    .section-11 .accordion.section .accordion-container .az-panel-title p {
      padding: 16px 24px 16px 15px;
    }
  
    .section-12 .green-banner {
      width: 82%;
      padding: 13px 0px 13px 38px;
    }
  
    .section-13 th,.section-13 td {
      padding: 0 !important;
    }
  
    .section-13 .patients {
      width: 100%;
      max-width: 393px;
      margin: 0 auto;
    }
  
    .section-13 .chart-body-copy {
      padding: 10px 15px 5px 15px !important;
    }
  
    .section-13 .chart-footnote {
      margin: 0 0 40px 0;
      text-indent: 0;
    }
  
    .section-13 .nccn-content-mob {
      background-color: #f1f1f1;
      padding: 10px 11px;
    }
  
    .resectable-nsclc .section-13 .nccn-block-mob, .resectable-nsclc .section-15 .nccn-block-mob {
      background: none;
      min-height: 0;
    }
  
    .resectable-nsclc .section-13 img.nccn-badge, .resectable-nsclc .section-15 img.nccn-badge {
      margin: 0 auto;
      display: block;
    }
  
    .resectable-nsclc .section-13 span.nccn-content-mob, .resectable-nsclc .section-15 span.nccn-content-mob {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/nccn-white-callout-mob.png) no-repeat center 1px;
    }
  
    .resectable-nsclc .section-13 span.nccn-content-mob {
      background-size: 100% 190px;
      margin: -55px auto 0;
      padding: 70px 12px 20px;
    }
  
    .resectable-nsclc .section-15 span.nccn-content-mob {
      background-size: 100% 240px;
      margin: -65px auto 0;
      padding: 65px 20px 10px;
    }
  
    .resectable-nsclc .section-15 .nccn-block-mob {
      margin-bottom: 28px;
    }
  
    .resectable-nsclc .nccn-block-mob {
      min-height: 243px;
      max-width: 253px;
      margin: 20px auto;
    }
  
    .span1 th {
      font-size: 16px;
      line-height: 17px;
      color: #333333;
    }
  
    .adaura-callout .green-banner {
      width: 80%;
      padding: 0px 0px 0px 35px;
    }
  
    .section-14 th {
      padding: 0;
    }
  
    .section-15 .nccn-content-mob {
      font-size: 12px;
      line-height: 15px !important;
      background-color: #f1f1f1;
    }
  
    .section-15 .rtt-box {
      flex-direction: column;
      margin: 25px auto;
    }
  
    .section-15 .rtt-section {
      /*width: 92%;*/
      width: 100%;
    }
  
    .primary-button {
      padding: 9px 36px;
      text-align: center;
    }
  
    .resectable-nsclc .section-11 img.placebo {
      top: 2px;
      left: 11px;
      position: relative;
      width: 57px;
      height: 63px;
    }
  
    .metastatic-nsclc .section-1 .eyebrow {
      margin: 34px 0 10px 0;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-1 .eyebrow {
      margin: 20px 0 5px 0;
      padding: 0 44px 10px 0;
    }
  
    .metastatic-nsclc .section-1 .subhead {
      margin: 0 0 20px 0;
      margin-top: 0 !important;
    }
  
    h2.slide-to-top.unpre-median.first-line.pfsmb.is-visible {
      margin-top: 17px;
    }
  #pfs > div.page-section-inner.container > div:nth-child(13) > div > h2{
    margin-bottom: 67px!important;
  }
    h2.slide-to-top.unpre-median.pt5.is-visible {
      padding-right: 32px;
      margin-bottom: 30px;
    }
  
    .metastatic-nsclc .section-1 .copy-per,.metastatic-nsclc .section-2 .copy-per {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/yr-shape-white.png) no-repeat;
      width: 118px;
      height: 83px;
      background-size: contain;
    }
  
    .resectable-nsclc.efficacy .section-11 .icons img {
      width: 40px;
      height: 40px;
    }
  
    .metastatic-nsclc .bar-graph1-copy .bottom-content {
      margin-top: 33px;
    }
  
    .metastatic-nsclc .bar-graph2-copy .bottom-content {
      margin-top: 20px;
    }
  
    .metastatic-nsclc .section-1 .copy-per p {
      padding: 25px 0 0 0;
      font: normal normal 800 54px/16px Barlow !important;
     /* letter-spacing: -0.32px;*/
      margin-top: -2px;
    }
  
    .metastatic-nsclc .section-1 .copy-per p {
      font-weight: 700 !important;
      padding-top: 23px !important;
      left: 6px;
      top: 6px;
      position: relative;
    }
    .metastatic-nsclc .section-1 .median-overall .copy-per p{
      padding-top: 23px !important;
      left: 0px;
      top: 0px;
      position: relative;
    }
  #pfs > div.page-section-inner.container > div:nth-child(2) > div > div > div.copy-per > p{
        left: 0px;
        top: 0px;
  }
    .metastatic-nsclc .section-1 .yr-txt {
      font-size: 23px !important;
      line-height: 16px !important;
    }
  
    .metastatic-nsclc .section-1 .copy-content-lg {
      font-size: 25px;
      line-height: 20px;
    }
  #pfs > div.page-section-inner.container > div:nth-child(8) > div > div > div.copy-content > span.extrabold.copy-content-lg.surviva-txt{
    padding: 0px 5px;
    text-align:center;
    font-size: 28px;
  }
    .meta-chemo-efficacy .median-overall .extrabold.copy-content-lg.surviva-txt{
      font-size:30px !important;
    }
  
    .metastatic-nsclc .section-1 .copy-content-med {
      margin-top: 5px;
      display: block;
      margin-bottom: -3px;
    }
  
    .metastatic-nsclc .section-1 .vs-txt {
      color: #333333;
      line-height: 9px;
      display: inline-block;
      margin-top: -7px;
    }
  
    .metastatic-nsclc .section-1 .accordion.section .accordion-container .az-panel-title p {
      /*padding: 7px 24px 7px 15px;*/
      padding: 8px 36px 8px 15px !important;
    }
    
    /* .metastatic-nsclc .section-1  sup {
      font-size: 50% !important;
      top: -0.7em;
    }*/
    
    .metastatic-nsclc .copy-content-med {
      font-size: 16px;
      line-height: 20px;
    }
  
    .metastatic-nsclc .section-1 .hr-txt {
      font-size: 14px;
      line-height: 20px;
    }
  
  
    .metastatic-nsclc .section-1 .box-center {
      margin: 20px auto 0;
      padding: 13px 0;
      margin-bottom: 55px !important;
    }
      #pfs > div.page-section-inner.container > div:nth-child(11) > div > div{
      margin-bottom:35px !important;
    }
  #pfs > div.page-section-inner.container > div:nth-child(16) > div > div{
    margin-bottom: 35px !important;
  }
  table.posthoc-table{
    margin-bottom: 10px !important;
  }
    .metastatic-nsclc .nccn-lockup-mob {
      margin: 30px 0 24px 0;
    }
  
    .metastatic-nsclc .nccn-mob-content {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/nccn-curve-mob.png) no-repeat;
      max-width: 253px;
      margin: -40px auto 27px auto;
      /* height: 200px; */
      height: 220px !important;
      background-size: cover;
      background-position: 1px -2px;
    }
  
    .top05 {
      top: -0.5em !important;
    }
  
    .metastatic-nsclc .nccn-mob-content p {
      padding: 50px 10px 0 15px;
    }
    /*.metastatic-nsclc p.content.purple-txt sup {
      top: -1em;;
    }*/
    
    .metastatic-nsclc .section-1 .copy-content {
      margin: 13px 0 15px 5px;
    }
  
    .efficacy .section-1 .copy-content {
      margin: 5px 0 12px 0px;
    }
  
    .efficacy .section-2 .accordion-container .panel-body {
      padding: 0 5px 15px;
    }
  
    .efficacy .section-3 .accordion-container .panel-body {
      padding: 15px 0;
    }
  
    .metastatic-nsclc .section-1 .nccn-footnotes {
      width: 100%;
      margin: 20px 0 20px 0 !important;
      text-indent: -2px;
    }
  
    .metastatic-nsclc .section-1 .last-footnote {
      margin: 20px 0 35px 0;
      text-indent: -2px !important;
    }
    /*.data-copy, .accordion.section,.adaura-acc-section {*/
    /*    max-width: 336px !important;*/
    /*    margin: 0 auto;*/
    /*}*/
    .metastatic-nsclc .section-2 .eyebrow {
      margin: 55px 0 0 0;
    }
  
    .metastatic-nsclc .section-2 .subhead {
      margin: 43px 0 25px 0;
    }
  
    .metastatic-nsclc .section-2 .copy-content {
      margin: 0;
      margin-top: 20px;
    }
  
    .metastatic-nsclc .section-2 .copy-per {
      margin-bottom: 10px;
    }
  
    .metastatic-efficacy .section-2 .copy-per {
      margin-bottom: -23px;
      margin-top: 13px;
    }
  
    .metastatic-nsclc .section-2 .lg-num {
      font: normal normal 700 57px/18px Barlow !important;
      line-height: 70px !important;
    }
  
    .metastatic-nsclc .section-2 .copy-content-lg {
      font-size: 28px;
      line-height: 23px;
      letter-spacing: -0.34px;
    }
  
    .metastatic-nsclc .section-2 .copy-content-md,.metastatic-nsclc .section-2 .copy-content-sm {
      line-height: 23px;
    }
  
    .metastatic-nsclc .section-2 .pfs-right-block {
      margin: 5px 0 0 0;
    }
  
    .metastatic-nsclc .section-2 .pfs-center-block.pfs-block1 {
      margin: 45px auto 0 auto;
    }
  
    .metastatic-nsclc .section-2 .pfs-center-block.pfs-block2 {
      margin: 15px auto 25px auto;
    }
  
    .metastatic-nsclc .section-2 .last-footnote {
      margin: 0 0 35px 0;
    }
  
    .metastatic-nsclc .section-3 h2 {
      margin: 5px 0 0 0;
    }
  
    .metastatic-nsclc .section-3 h2.pfs-before-tabs-1 {
      margin: 50px 0 10px 0;
      letter-spacing: -0.01em;
    }
  
    .EGFR-mutation-type-inner:first-child {
      margin-bottom: 35px;
    }
      .EGFR-mutation-type-inner{
        max-width:340px;
        max-height: 235px;
    }
    .metastatic-nsclc .section-3 .subhead {
      margin: 27px 0 20px 0;
    }
  
    .metastatic-nsclc .section-4 .green-banner {
      margin: 20px 0 30px 0;
      width: 88%;
      padding: 18px 0px 18px 38px;
    }
  
    .metastatic-nsclc .section-5 .last-footnote {
      margin: 0 0 35px 0;
    }
  
    .metastatic-nsclc .section-6 h1 {
      margin: 55px 0 20px 0;
    }
  
    .metastatic-nsclc .section-6 .graphic-box {
      height: 564px;
      margin: 100px auto 63px auto;
      border-radius: 15px;
    }
  
    .metastatic-nsclc .section-6 .graphic-subhead {
      left: 80px;
      top: -71px;
      width: 69%;
      padding-left: 22px;
    }
  
    .metastatic-nsclc .section-6 .cns-arrow-section {
      flex-direction: column;
      margin: 80px 0 0 0;
    }
  
    .metastatic-nsclc .section-6 .cns-block {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/cns-arrow-shape.png)no-repeat;
      width: 159px;
      height: 119px;
      margin: 0 0 40px 0;
      padding: 27px 0 0 0;
      transition: 1s all ease-out;
    }
  
    .metastatic-nsclc .section-6 .cns-block span {
      font-size: 50px;
      line-height: 60px;
      background: none;
      width: auto;
      height: auto;
      padding: 0;
      background-size: 100% auto;
      left: auto;
      position: relative;
      transition: 1s all ease-out;
    }
  
    .metastatic-nsclc .section-6 .cns-block2 {
      transform: translateY(-130px);
    }
  
    .metastatic-nsclc .section-6 .cns-block3 {
      transform: translateY(-260px);
    }
  
    .metastatic-nsclc .section-6 .copy-content-lg {
      font-size: 28px;
      line-height: 27px;
    }
  
    .metastatic-nsclc .section-6 .copy-content-sm {
      line-height: 27px;
      color: #5A5B5E;
    }
  
    .metastatic-nsclc .section-6 .is-visible .cns-block2, .metastatic-nsclc .section-6 .is-visible  .cns-block3 {
      transform: none;
    }
  
    .metastatic-nsclc .section-6 .subhead3 {
      margin: 0 0 30px 0;
    }
  
    .metastatic-nsclc .section-6 .bullet-list {
      margin: 45px 0 25px 0;
    }
  #cns-data > div.page-section-inner.container > div:nth-child(14) > div > ul{
    margin-bottom:0;
    padding-bottom: 25px !important;
  }
    #flaura2 > div.page-section-inner.container > div:nth-child(1) > div > p{
      padding-top:40px;
    }
    .metastatic-nsclc .section-6 .subhead4 {
      margin: 47px 0 30px 0;
    }
  
    .metastatic-nsclc .section-6 .last-footnote {
      margin: 0 0 43px 0;
    }
  
    .metastatic-nsclc .section-6 .brain-icon {
      margin: 0;
      left: 26px;
      top: -65px;
    }
  
    .metastatic-nsclc .section-6 .cns-block p {
      top: -29px;
      left: 43px;
    }
  
    .metastatic-nsclc .section-6 .cns-block1 p {
      left: 30px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-one {
      width: 73px;
      height: 105px;
      left: 12px;
    }
  
    .bar-graph1-copy {
      position: absolute;
      top: 48px;
      left: 91px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar-two.bar-container {
      width: 73px;
      right: 51px;
      height: 116px;
    }
  
    .metastatic-nsclc .section-6 .is-visible .bar-two.bar-container,.metastatic-nsclc .section-6 .is-visible .bar-one {
      min-height: 0;
    }
  
    .metastatic-nsclc .section-6 .is-visible .bar.small-bar {
      min-height: 0;
    }
  
    .bar-graph2-copy {
      left: 95px;
      top: -37px;
    }
  
    .bottom-content {
      margin: 10px 0 0 0;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar.small-bar {
      top: -24px;
      width: 73px;
      height: 24px;
    }
  
    .metastatic-nsclc .section-6  p.vertical-txt {
      left: -9px;
      top: -20px;
      font-size: 12px;
      line-height: 14px !important;
    }
  
    .bar-graph1-copy p,.bar-graph2-copy p {
      margin: 0;
      font-size: 10px;
      line-height: 10px !important;
    }
  
    .bar-graph1-copy span,.bar-graph2-copy span {
      font-size: 31px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar p {
      font-size: 31px;
      line-height: 20px !important;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar span {
      font-size: 10px;
      line-height: 10px !important;
    }
  
    .bar-graph2-copy {
      left: 81px;
      top: 1px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt {
      top: -48px;
      width: 100%;
      text-align: center;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt p {
      padding-bottom: 4px;
      margin-left: -3px;
    }
  
    .hor-txt1 {
      position: absolute;
      bottom: 0px;
      left: 22px;
    }
  
    .hor-txt2 {
      bottom: 0px;
      right: 40px;
    }
  
    .hor-txt {
      font-size: 12px;
      line-height: 14px !important;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph ul.scale {
      top: 12px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
      max-width: 269px;
      margin-left: 47px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
      margin-top: 38px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph li.ruler {
      height: 35px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph hr.ver-line {
      height: 175px;
      margin-top: 15px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-container {
      position: relative;
      max-width: 339px;
      margin: 0 auto;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-one {
      width: 80px;
      height: 74px;
      left: 47px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-two {
      width: 206px;
      height: 74px;
      left: 47px;
    }
  
    .metastatic-nsclc .section-6 .hor-line {
      width: 100%;
      left: 14px;
      max-width: 271px;
      margin: 0 auto;
      height: 216px;
    }
  
    .metastatic-nsclc .section-6 ul.hor-scale {
      left: 6px;
      bottom: 2px;
    }
  
    .metastatic-nsclc .section-6 ul.hor-scale {
      max-width: 326px;
      margin: 0 auto 20px;
      left: 0;
      right: 0;
    }
  
    .metastatic-nsclc .section-6 .bar-chart-horizontal .hor-bar-one p {
      position: absolute;
      right: -36px;
      top: 28px;
    }
  
    .hor-bar span {
      font-size: 31px;
    }
  
    .metastatic-nsclc .section-6 .bar-chart-horizontal .hor-bar-two.hor-bar p {
      top: 28px;
      right: -48px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1,.metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
      font-size: 12px;
      line-height: 14px !important;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
      left: -15px;
      bottom: 152px;
      text-align: right;
    }
  
    .metastatic-nsclc .section-6 .hor-ruler {
      width: 66px;
    }
  
    .metastatic-nsclc .section-6 li.hor-ruler:nth-last-child(1) {
      width: 8px;
      right: 4px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
      bottom: 48px;
      left: -12px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-two.hor-bar {
      bottom: 25px;
      margin-bottom: 20px;
      transition: none;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-one.hor-bar {
      bottom: 119px;
      margin-bottom: 20px;
      transition: none;
    }
  
    ul.hor-scale {
      width: 100%;
      height: 14px;
      position: absolute;
      left: -7px;
      bottom: -6px;
    }
  
    .metastatic-nsclc .section-6 .is-visible .hor-bar-one {
      min-width: 0;
    }
  
    .metastatic-nsclc .section-6 .is-visible .hor-bar-two {
      min-width: 0;
    }
  
    .metastatic-nsclc .section-7 .green-banner {
      margin: 40px 0 40px 0;
    }
  
    .metastatic-nsclc .section-8 .last-footnote {
      margin: 0 0 35px 0;
    }
  
    .metastatic-nsclc .section-9 h1 {
      margin: 55px 0 20px 0;
    }
  
    .metastatic-nsclc .section-9 .accordion.section {
      margin: 35px auto 25px auto;
    }
  #flaura2 > div.page-section-inner.container > div:nth-child(11){
    margin-bottom: 45px;
  }
    .metastatic-nsclc .section-9 .visit-btn {
      margin: 40px auto;
    }
  
    .metastatic-nsclc .section-9 .accordion.section .accordion-container .az-panel-title p {
      /*padding: 18px 24px 18px 15px;*/
      padding: 15px 24px 18px 15px;
    }
  
    .metastatic-nsclc .section-9  .endpoint-block {
      margin: 0px 0;
    }
  
    .metastatic-nsclc .section-9  .endpoint-block p {
      margin-bottom: 15px;
    }
  
    .metastatic-nsclc .section-9  .primary-button {
      padding: 7px 36px;
    }
  
    .metastatic-nsclc .section-9  table.customTable {
      margin: 0 !important;
    }
  
    .metastatic-nsclc .section-9 .customTable td {
      padding: 0 5px !important;
    }
  
    .metastatic-nsclc .section-9 .customTable th {
      line-height: 19px !important;
      letter-spacing: -0.14px;
      padding-left: 4px;
    }
  
    .metastatic-nsclc .section-9 .customTable th:last-child {
      text-align: center !important;
      top: 0px;
      position: relative;
    }
  
    .metastatic-nsclc .flaura-section {
      flex-direction: column;
    }
  
    .block2 img {
      display: inline-block;
      margin: 0 20px 10px 30px;
    }
  
    .block1 {
      margin: 0;
    }
  
    .block3 {
      display: flex;
    }
  
    .img1 {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/efficacy-purple-arrow-down.png) no-repeat;
      width: 159px;
      height: 164px;
      margin: 0 0 35px 0;
    }
  
    .section-9 .img1 {
      margin-bottom: 14px;
    }
  
    .img2 {
      height: 165px;
      padding: 13px 16px 0 15px;
      width: 161px;
      margin-left: 15px;
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/efficacy-grey-arrow-down.png) no-repeat;
    }
  
    .img2 p:nth-child(2) {
      margin-bottom: 10px;
    }
  
    .img2 p:nth-child(1) {
      line-height: 15px !important;
    }
  
    .img2 p:nth-child(2), .img2 p:nth-child(3) {
      line-height: 15px !important;
      letter-spacing: -0.38px;
    }
  
    .img1 p {
      padding: 45px 30px;
    }
  
    .metastatic-efficacy .flaura-accordian .panel-body {
      padding: 12px 9px 10px 0 !important;
    }
  
    .ratio-lg {
      padding-top: 12px;
    }
  
    img.placebo {
      left: 34px;
      top: 3px;
      position: relative;
    }
  
    img.az-80-pill-bottle {
      position: relative;
      top: 5px;
      right: 26px;
    }
  
    .red-83 {
      font-weight: 700;
    }
  
    th.purple-txt.adaura-table-color:nth-child(1) {
      text-align: left;
      padding-left: 10px;
    }
  
    th.purple-txt.adaura-table-color {
      color: #5B305D;
    }
  
    .section-10 .hor-bar-container .left-bar-data2 {
      bottom: 104px;
    }
  
    .section-10 .hor-bar-two {
      bottom: 68px;
    }
  
    .section-10 .hor-bar-container .left-bar-data1 {
      bottom: 232px;
    }
  
    .section-10 .hor-bar-one {
      bottom: 192px;
    }
  
    .resect-efficacy .section-10 .num-lg {
      font-size: 31px;
    }
  
    #os .panel-default>.panel-heading+.panel-collapse>.panel-body {
      overflow: hidden;
    }
  
    #dfs .panel-body img {
      width: auto;
      max-width: 362px;
      margin-left: -10px;
      margin-bottom: -10px;
      margin-top: -5px;
    }
  
    .surgery-and-treat-icon.mobile-only,.surgery-chemo-treat-icon.mobile-only {
      position: relative;
      top: 8px;
      max-width: 202px;
      height: 94px;
    }
  
    .section-11 .sect-7 span {
      line-height: 16px;
    }
  
    ul.box-unaccept {
      margin-top: 5px;
    }
  
    span.icons {
      margin-bottom: 12px;
    }
  
    .dna-icon {
      margin-bottom: 3px !important;
    }
  
    .icon-head {
      margin-bottom: 4px;
      margin-top: 15px;
    }
  
    .who-ps {
      line-height: 18px !important;
    }
  
    .treat-dna-icon {
      position: relative;
      top: 10px;
    }
  
    .efficacy.resectable-nsclc .section-15 .box-3 .az-280-treat-and-bottle-icon {
      width: 99px !important;
    }
    /***********************dfs******************/
    .efficacy.resectable-nsclc .section-4 .final-analysis-link .final-analysis-text a, .efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text a,
    .efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text a {
      font: normal normal 700 20px/24px Barlow !important;
    }
  
    .efficacy.resectable-nsclc .section-4 .final-analysis-link, .efficacy.resectable-nsclc .section-7 .final-analysis-link {
      max-width: 270px;
    }
  
    .efficacy.resectable-nsclc .section-10 .final-analysis-link {
      max-width: 270px;
    }
  
    .efficacy.resectable-nsclc .section-4 .final-analysis-link .final-analysis-text, .efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/final-analysis-bg-mobile.png) no-repeat;
      background-size: 269px 60px;
      padding: 15px 25px;
    }
  
    .efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/final-analysis-bg-mobile.png) no-repeat;
      background-size: 269px 60px;
      padding: 15px 25px;
    }
  
    .final-analysis-link .final-analysis-text {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/final-analysis-bg-mobile.svg) no-repeat;
      padding: 18px 20px 24px 20px;
      margin-bottom: 0;
    }
  
    .final-analysis-link {
      max-width: 210px;
      margin: 23px auto 10px;
    }
  
    .efficacy.resectable-nsclc .section-4 .eyebrow {
      margin-top: 0 !important;
      line-height: 36px !important;
      margin: 55px 0 16px 0;
    }
  
    .efficacy.resectable-nsclc .section-4 h2.consistent-dfs {
      margin-top: -8px;
    }
  
    .efficacy.resectable-nsclc .section-4 .subhead2 {
      margin: 40px 0 22px 0;
    }
  
    .efficacy.resectable-nsclc .section-4 .adj-table {
      margin: 10px auto 38px auto !important;
    }
  
    .efficacy.resectable-nsclc .section-5 .green-banner {
      margin: 32px 0 25px 0;
      /*width: 85%;*/
      ;
    }
  
    .efficacy.resectable-nsclc .section-7 .eyebrow {
      margin: -5px 0 0 0;
      line-height: 36px !important;
    }
  
    .efficacy.resectable-nsclc .section-7 h2.consistent-dfs {
      margin-top: 8px;
    }
  
    .efficacy.resectable-nsclc .section-4 .stage-61-text .copy-content-lg,
    .efficacy.resectable-nsclc .section-4 .stage-61-text .txt-md {
      line-height: 29px;
    }
  
    .efficacy.resectable-nsclc .section-7 .adaura-km-chart {
      margin: 20px auto 0 auto;
    }
  
    .efficacy.resectable-nsclc .section-7 .adaura-km-chart .copy-per.hr-image {
      margin-bottom: 0px;
      transform: none;
      padding: 12px;
      height: auto !important;
      margin-top: 10px !important;
    }
  
    .efficacy.resectable-nsclc .section-7 .adaura-km-chart .surgery-and-treat-icon {
      max-width: 145px;
      height: 92px;
      margin-top: 10px;
    }
  
    .efficacy.resectable-nsclc .updated-copy-hr p.purple-txt.ffb-b.lg-num {
      padding-top: 0 !important;
      margin-top: 12px !important;
      margin-bottom: 10px !important;
    }
  
    .efficacy.resectable-nsclc .section-7 .adaura-km-chart p.prior-per {
      margin-bottom: 18px;
    }
  
    .efficacy.resectable-nsclc .section-7 .adaura-km-chart p.or-txt {
      margin: 124px auto  20px!important;
      display: none;
    }
  
    #eff-sm-box-fix-a {
      /*position: relative;*/
      /*top: -150px;*/
      /*margin-bottom: -80px;*/
      position: relative;
      top: 0;
      margin-bottom: 10px;
    }
  
    .efficacy.resectable-nsclc .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-1 .sm-callout p {
      padding: 33px 16px 34px 16px;
    }
  
    .efficacy.resectable-nsclc .section-7 .adaura-km-chart .sm-callout p {
      margin-bottom: 29px;
    }
  
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one.hor-bar {
      margin-bottom: -6px !important;
    }
  
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second.hor-bar {
      margin-bottom: 0px !important;
    }
  
    .efficacy.resectable-nsclc .section-1 .eyebrow.res-text {
      font: 13px/16px Barlow !important;
      opacity: 1;
      font-weight: 500;
      margin: 13px 0 0 0;
    }
  
    .efficacy.resectable-nsclc .section-1 h2.new-data {
      font: normal normal 800 36px/43px Barlow;
      color: #5B305D;
      opacity: 1;
    }
  
    h2.egfr-mutation.new-datatwo {
      font: normal normal 20px/31px Barlow;
      color: #5B305D;
    }
  
    .efficacy.resectable-nsclc .section-10 .hor-bar p b {
      font: normal normal 400 12px/12px Barlow;
    }
  
    .efficacy.resectable-nsclc .section-4 .subhead {
      margin: 16px 0 28px 0;
    }
  
    .efficacy.resectable-nsclc .section-4 .subhead2 {
      margin-top: 30px;
    }
  
    .efficacy.resectable-nsclc .section-1 h2.egfr-mutation.new-datatwo {
      margin-top: 0px !important;
      font-weight: 500;
      line-height: 20px;
    }
  
    .efficacy.resectable-nsclc .section-1 h2.new-data {
      font-weight: 800;
    }
  
    .efficacy.resectable-nsclc img.stage-61 {
      width: 130px;
      height: revert;
    }
  
    .efficacy.resectable-nsclc .section-5 .green-banner p {
      font-weight: 600;
    }
  
    .efficacy.resectable-nsclc .section-4 .stage61-chart {
      width: 95%;
      margin: 0 auto;
      text-align: center;
    }
  
    .efficacy.resectable-nsclc .section-1 h2.new-data, .efficacy.resectable-nsclc .section-1 .egfr-mutation.new-datatwo {
      padding: 0;
      margin: 0;
    }
  
    .resectable-nsclc .section-10 .hor-ruler {
      width: 56px;
      margin-right: 4px;
    }
  
    .resectable-nsclc .section-10 .hor-ruler:last-child {
      width: 0px;
      right: -8px;
      position: absolute;
      bottom: -3px;
    }
  
    .efficacy.resectable-nsclc .section-1 .egfr-mutation.analysis-text {
      box-shadow: inset 0px 2px 3px #00000029;
      border: 2px solid #CEDB00;
      border-radius: 8px;
      opacity: 1;
      text-align: center;
      font: normal normal 800 19px/20px Barlow;
      letter-spacing: 0.19px;
      color: #5B305D;
      margin: 15px auto 23px auto;
      padding: 22px;
    }
  
    .efficacy.resectable-nsclc .section-1 .egfr-mutation.analysis-text {
      box-shadow: inset 0px 0px 3px #00000029;
    }
  
    .efficacy.resectable-nsclc .section-1 .eyebrow.dfs-eyebrow {
      font: normal normal 14px/18px Barlow !important;
      letter-spacing: 0.14px;
      color: #5B305D;
      margin-top: 0;
      font-weight: 500 !important;
    }
  
    .efficacy.resectable-nsclc .section-1 .subhead.finaldfsdata {
      text-align: center;
      font: normal normal 800 26px/30px Barlow;
      color: #5B305D;
      padding-top: 16px;
      border-top: 1px solid #5B305D;
      margin-bottom: 5px;
    }
  
    .efficacy.resectable-nsclc .section-1 .bracket-text {
      text-align: center;
      font: normal normal normal 13px/24px Barlow;
      letter-spacing: 0.13px;
      color: #5B305D;
      margin-bottom: 20px;
    }
  
    .efficacy.resectable-nsclc .section-1 .copy-per.dfs-copy p {
      font: normal normal 700 52px/16px Barlow !important;
      letter-spacing: -0.31px;
      padding-top: 23px !important;
    }
  
    .efficacy.resectable-nsclc .section-1 .copy-per {
      margin: 8px 0 0 0px !important;
    }
  
    .efficacy.resectable-nsclc .section-1 .dfs-copy .copy-content-lg {
      font: 500 22px/16px Barlow !important;
      letter-spacing: -0.13px;
    }
  
    .efficacy.resectable-nsclc .section-1 .dfs-content .copy-content-lg {
      font: normal normal 800 30px/27px Barlow !important;
      opacity: 1;
    }
  
    .efficacy.resectable-nsclc .section-1 .dfs-content span.ffb-med.copy-content-med {
      font: normal normal 15px/17px Barlow;
      max-width: 230px !important;
      margin: 0 auto;
      display: block;
      color: #5A5B5E;
      color: #5B305D;
    }
  
    #eff-table-height-fix-a td, #eff-table-height-fix-a th {
      line-height: 25px;
    }
  
    .section-4 .adj-table th:first-child {
      width: 154px !important;
      padding: 0px 5px 0px 10px !important;
    }
  
    .efficacy.resectable-nsclc .section-1 .accordion-group.panel .panel-body {
      padding: 15px 3px 10px 5px;
    }
  
    .efficacy.resectable-nsclc .section-1 .dfs-content span.percentage-text {
      color: #5A5B5E;
      line-height: 27px !important;
    }
  
    .efficacy.resectable-nsclc .section-1 .dfs-content {
      /*margin: 5px 0 8px 0px;*/
      /*max-width: 95%;*/
      margin: 7px 13px 14px 13px;
      max-width: 98%;
      display: block;
    }
  
    .efficacy.resectable-nsclc .section-1 .new-image.seventythreeper {
      max-width: 190px;
      min-height: 208px;
      margin: 0 auto;
      padding: 6px 0 0;
    }
  
    .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data2 br.mobile-only {
      display: none;
    }
  
    .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content {
      margin: 47px auto 30px auto;
    }
  
    .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box {
      padding: 0;
      min-height: 225px;
    }
  
    .newsection-content span.tab-row1, .newsection-content span.tab-row4 {
      margin-left: 10px;
    }
  
    .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box {
      position: relative;
      border: 2px solid grey;
      border-radius: 20px;
      padding: 35px 0 0px 0;
      margin: 70px auto 30px auto;
      max-width: 650px;
    }
  
    .efficacy.resectable-nsclc .section-1 .newsection-content .dfs-content-box .abs-top {
      background: #fff;
      margin: auto;
      top: -38px;
      width: 85%;
    }
  
    .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul {
      padding: 0;
      margin: -12px 2px 0px 23px;
    }
  
    .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li {
      display: inline-block;
      list-style: none;
      width: 32%;
      margin-left: -4px;
      text-align: center;
      padding: 0;
    }
  
    .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li span {
      display: block;
    }
  
    .efficacy.resectable-nsclc .section-1 .dfs-content-box .subhead {
      position: absolute;
      top: -23px;
      width: 87%;
      left: 0;
      right: 0;
      letter-spacing: -0.09px;
    }
  
    .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-head {
      font: 700 16px/19px Barlow;
      letter-spacing: -0.54px;
      color: #4E5055;
      text-transform: uppercase;
      border-bottom: 1px solid #707070;
      padding-bottom: 5px;
      padding-left: 0px;
      padding-top: 8px;
    }
  
    .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row1 {
      font: normal normal bold 36px/43px Barlow;
      letter-spacing: 0px;
      color: #5B305D;
      margin-top: 3px;
    }
  
    .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row1, 
    .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row4 {
      position: relative;
    }
  
    .efficacy.resectable-nsclc .section-1 span.tab-row2 {
      font: normal normal 600 13px/16px Barlow;
      letter-spacing: -0.33px;
      color: #5B305D;
      opacity: 1;
      margin-top: -3px;
    }
  
    .newsection-content span.tab-row5 {
      margin-bottom: 15px !important;
    }
  
    .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row3 {
      width: 46px;
      height: 9px;
      opacity: 1;
      border-radius: 50%;
      text-align: center;
      display: block;
      margin: 0px auto 17px auto;
      position: relative;
      left: -1px;
      top: 4px;
    }
  
    .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-row4 {
      top: -3px;
      font: normal normal normal 36px/43px Barlow;
      letter-spacing: 0.4px;
      color: #4E5055;
    }
  
    .efficacy.resectable-nsclc .section-1 span.tab-row5 {
      font: normal normal normal 13px/16px Barlow;
      letter-spacing: -0.33px;
      color: #4E5055;
    }
  
    .efficacy.resectable-nsclc .section-1 .newsection-content li.years-2, .efficacy.resectable-nsclc .section-1 .newsection-content li.years-3 {
      border-right: 1px solid #707070;
    }
  
    .efficacy.resectable-nsclc .section-1 p.subhead.median-text {
      margin: 0px 0 20px;
      letter-spacing: -0.09px;
    }
  
    .efficacy.resectable-nsclc .section-1 .nccn-content-mob {
      padding: 2px 10px 18px;
    }
    
    /* update */
    
    #resec-nccn-badge-fix-00 {
      background-size: contain;
    }
  
    #resec-nccn-badge-fix-01 {
      padding: 40px 10px 12px;
      background-size: cover !important;
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/nccn-curve-mob.png) no-repeat;
      background-position: top center;
      max-width: 252px;
      margin-top: 60px;
    }
  
    img#resec-nccn-badge-fix-02 , img#resec-nccn-badge-fix-04 {
      width: 253px !important;
      margin-bottom: -25px;
    }
  
    #resec-nccn-badge-fix-03 {
      background: white;
      padding: 0px 8px 25px 12px;
      margin-top: 43px;
      margin-bottom: 20px;
    }
  
    span#resec-nccn-badge-fix-05 {
      background: white;
      padding: 0px 10px 10px 12px;
      margin-top: 43px;
      font-size: 16px;
      line-height: 20px !important;
    }
  
    p#surgeon-subhead-margin-b {
      margin-top: 60px;
    }
  
    div#eff-teal-banner-btm {
      margin-bottom: 60px;
    }
  
    .efficacy.resectable-nsclc .section-5 .green-banner {
      padding-left: 36px!important;
      width: 79%!important;
      margin: 25px 0 41px -16px!important;
    }
  
    .efficacy.resectable-nsclc .adaura-callout .green-banner {
      width: 87.5%;
    }
  
    ul#eff-bullet-rethink-fix {
      margin-left: -23px;
    }
  
    #eff-bullet-rethink-fix > li::marker {
      color: #008995;
    }
  
    div#resect-eff-margin-top-a {
      margin-top: 60px;
    }
  
    p#eff-stage-box-copy-a {
      font-size: 14px;
    }
  
    span#eff-stage-box-copy-b {
      font-size: 32px;
    }
  
    .efficacy.resectable-nsclc .subgroup-header-part .consistent-dfs {
      font-size: 30px !important;
    }
  
    .nccn-eff-footnotes-container-a {
      margin: 0px 10px 0px -30px !important;
    }
  
    .efficacy ul.median-list-1 {
      margin-bottom: 40px;
    }
  
    .nccn-eff-footnotes-container-b {
      margin: -15px -15px 0px -14px !important;
    }
  
    div#sm-box-margin-btm-b {
      margin-top: -5px;
      margin-bottom: -10px;
    }
    
    
    /* end */
    
    .efficacy.resectable-nsclc .section-2 .green-banner p {
      padding: 15px 0 18px 0 !important;
      font-weight: 600;
    }
  
    .efficacy.resectable-nsclc .section-2 .green-banner {
      margin: 40px 0 20px 0 !important;
    }
  
    .efficacy.resectable-nsclc .section-2 .green-banner {
      /*padding: 0px 0px 0px 28px;*/
      padding: 0px 0px 0px 22px;
    }
  
    .efficacy.resectable-nsclc .section-3 .dfs-footnote {
      margin-bottom: 35px !important;
    }
  
    .efficacy.resectable-nsclc .updated-copy-hr {
      margin-bottom: 22px !important;
    }
  
    .efficacy.resectable-nsclc .section-10 .eyebrow {
      line-height: 36px !important;
      margin: 20px 0 7px 0;
    }
  
    .efficacy.resectable-nsclc .section-10 .brain-section:after {
      height: 162px;
    }
  
    .efficacy.resectable-nsclc .section-10 .brain-section {
      max-width: 330px;
      /* margin: 45px auto 80px auto; */
      margin: 50px 11px 74px 0 !important;
    }
  
    .efficacy.resectable-nsclc .section-10 .lg-num {
      font-size: 54px;
    }
  
    .efficacy.resectable-nsclc .section-10.btm-shadow span.ffb-b.cns-text {
      line-height: 18px;
      margin-bottom: 2px;
      padding: 0px 26px;
    }
  
    .efficacy.resectable-nsclc #cns .cns-last-footnotes {
      padding-left: 12px;
    }
  
    .resect-efficacy .section-10 .num-lg {
      font-size: 34px;
    }
  
    .efficacy.resectable-nsclc .section-10 .hor-bar p {
      line-height: 12px !important;
      top: 30px !important;
      margin-bottom: 0;
    }
  
    .efficacy.resectable-nsclc .section-10 .check-box-one {
      margin-bottom: 3px;
    }
  
    .efficacy.resectable-nsclc .section-10 .bullet-list {
      margin: 25px 0 15px 7px;
    }
  
    .efficacy.resectable-nsclc #cns .refer-section {
      max-width: 90%;
      margin: 0 auto;
      display: block;
      position: relative;
    }
  
    .efficacy.resectable-nsclc .section-10 .brain-icon-efficacy-mob {
      top: -38px;
      left: 6px;
      width: 98px;
      height: 98px;
    }
  
    .efficacy.resectable-nsclc .section-10 .brain-img-txt {
      top: 26px;
      left: 15px;
    }
  
    .efficacy.resectable-nsclc .section-10 .hor-line {
      margin-top: 5px;
    }
  
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one.hor-bar {
      min-width: 66px !important;
      margin-bottom: 0px;
    }
  
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second.hor-bar {
      min-width: 53px;
    }
  
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two {
      margin-bottom: 5px;
    }
  
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second {
      margin-bottom: 6px;
    }
  
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two.hor-bar {
      min-width: 165px;
    }
  
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two-second.hor-bar {
      min-width: 97px;
    }
  
    .efficacy.resectable-nsclc .hor-bar-one-second {
      margin: 0 0 23px 0;
      left: 66px;
    }
  
    .efficacy.resectable-nsclc .hor-bar-two-second {
      background: #AEB0B3;
      min-width: 0px;
      position: absolute;
      height: 92px;
      bottom: 68px;
      left: 499px;
      margin: 0 0 32px 0;
      transition: 1s all ease;
      transition-delay: 1s;
      opacity: 0;
      z-index: 2;
    }
  
    .efficacy.resectable-nsclc .section-10 .hor-bar p, .efficacy.resectable-nsclc .hor-bar span, 
    .efficacy.resectable-nsclc .section-10 .hor-bar-two.hor-bar p {
      color: #ffffff;
      line-height: 12px;
    }
  
    .efficacy.resectable-nsclc .section-10 .hor-bar-one p, .efficacy.resectable-nsclc .section-10 .hor-bar-one-second p, 
    .efficacy.resectable-nsclc .section-10 .hor-bar-two-second p, .efficacy.resectable-nsclc .section-10 .hor-bar-two.hor-bar p {
      top: 30px;
      position: absolute;
      text-align: right;
    }
  
    .efficacy.resectable-nsclc .section-10 .hor-bar-one p,
    .efficacy.resectable-nsclc .section-10 .hor-bar-two-second p {
      right: 9px !important;
    }
  
    .efficacy.resectable-nsclc .section-10 .hor-bar-one-second p {
      right: 6px !important;
    }
  
    .efficacy.resectable-nsclc .section-10 .hor-bar-two p {
      right: 10px !important;
    }
  
    .efficacy.resectable-nsclc .hor-bar-two-second {
      left: 165px;
      margin: 0 0 5px 0;
    }
  
    .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data1, 
    .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data2 {
      font-size: 12px;
    }
  
    .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data1 {
      left: -66px;
      bottom: 208px;
    }
  
    .resectable-nsclc.efficacy .section-10 .hor-bar-container .left-bar-data2 {
      left: -70px;
      bottom: 82px;
    }
  
    .resectable-nsclc.efficacy .section-10 .hor-line {
      width: 256px;
      height: 244px;
    }
  
    .resectable-nsclc.efficacy .recurrence-section {
      width: 240px;
    }
  
    .resectable-nsclc.efficacy .recurrence-cns-text, .resectable-nsclc.efficacy .Local-regional-text {
      width: 120px;
    }
  
    .resectable-nsclc.efficacy .recurrence-section .recurrence-right {
      font-size: 12px;
      line-height: 14px;
      text-align: left;
      padding-left: 7px;
      color: #333333;
    }
  
    img.stage-61 {
      max-width: 135px;
    }
  
    .resectable-nsclc.efficacy .percentage-bar-text {
      font-size: 12px;
      line-height: 19.2px !important;
    }
  
    .efficacy.resectable-nsclc .section-1 {
      border-top: 8px solid #CEDB00;
    }
  
    .efficacy.resectable-nsclc .section-15 .footnotes.nccn-footnotes {
      width: 92%;
    }
  
    .fsd-img-one {
      right: 38px !important;
    }
  
    .fsd-img-two {
      left: 62px !important;
    }
  
    .efficacy-gb-sec {
      padding: 0px 0px 0px 38px !important;
    }
  
    .footnotes {
      font-weight: 400;
      font-size: 12px;
      line-height: 16px !important;
      color: #333333;
      margin-bottom: 0px;
      text-indent: -5px;
      /* padding-left: 5px; */
      /* margin-left: 2px; */
      ;
    }
  .first-line-footnote{
    margin-bottom:10px
  }
    #pfs > div.page-section-inner.container > div:nth-child(10) > div > p:nth-child(8) {
      text-indent: -9px;
    }
  
    .panel.panel-default.az-accordion-panel.verticalSlide p {
      padding-bottom: 10px;
      margin-bottom: 0px;
    }
    
     /****81422*****/
    .meta-chemo-efficacy .panel.panel-default.az-accordion-panel.verticalSlide #sample-collapse1731974089 p, #pfs .panel-collapse p {
      padding-bottom: 10px !important;
      line-height: 20px !important;
      text-align: left;
    }
  #pfs .panel-collapse p.teal-txt,
  #pfs .panel-collapse p{
  padding: 10px 8px;
  }
    
    /*#pfs .panel-collapse p {*/
          /*padding-bottom: 15px!important;*/
    /*  ;*/
    /*}*/
  p.footnotes.text-center.bullet.interim-footnote{
    text-indent:unset;
    padding:0 8px;
    text-align:left;
    margin-bottom: 6px !important;
  }
    .median-chart p.footnotes.text-center.bullet.interim-footnote{
      text-align: center;
      margin: 0 !important;
      margin: 10px 3px 5px 9px !important;
      font-size: 15px;
    }
     .median-chart p.footnotes.text-center.bullet.interim-footnote:last-child{
    max-width: fit-content;
    /* padding: 0 13px; */
    margin: 0 10px 10px 10px!important;
    }
    .chart-copy.mobile-only {
      max-width: 310px;
      margin: 0 auto;
    }
  
    .efficacy sup {
      top: -0.5em !important;
    }
  
    .metastatic-nsclc.meta-chemo-efficacy .nccn-mob-content p {
      padding: 36px 10px 0 15px;
      /*text-align: center;*/
    }
  
    .meta-chemo-efficacy .panel.panel-default.az-accordion-panel.verticalSlide #sample-collapse-1201635664 p, #without-cns .panel-collapse p {
      padding-bottom: 5px!important;
    }
  
    #without-cns .panel-collapse p {
      padding-bottom: 0px !important;
      margin-bottom: -15px;
    }
  
    #with-cns img {
      margin-bottom: -19px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-line {
      height: 207px;
      border-top: 0;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-one,.meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-two {
      height: 61px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-two {
      min-width: 189px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .bar-chart-horizontal .hor-bar-one p {
      top: 17px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .bar-chart-horizontal .hor-bar-two.hor-bar p {
      top: 17px;
    }
  
    .meta-chemo-efficacy  #flaura-study-design.section-9,
      .meta-chemo-efficacy  #flaura2.section-9 {
      margin-top: 0;
    }
  
    .meta-chemo-efficacy #flaura-study-design.section-9 h2.slide-to-top.unpre-median.before-control-arm.is-visible,
    .meta-chemo-efficacy #flaura2.section-9 h2.slide-to-top.unpre-median.before-control-arm.is-visible {
      margin-bottom: 10px;
    }
  
    .metastatic-nsclc.meta-chemo-efficacy .section-1 .panel-body img {
        /*bottom: 4px;*/
      bottom: -10px;
      padding: 3px;
    }
  
    .os-block .dosingTitle, .dor-orr-block .dosingTitle {
      left: 60px;
      padding: 0 5px;
      max-width: 207px;
      text-align: center;
      top: -28px;
    }
  
    .os-block {
      padding: 50px 30px 15px 30px;
    }
  
    .os-div {
      flex-direction: column;
      align-items: center;
    }
  
    .os-div img {
      content: url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/mobile/Mobile_OS.png);
      margin-right: 0;
    }
  
    .os-div>div {
      text-align: center;
    }
  
    .dor-orr-block .dosingTitle {
      max-width: 255px;
      left: 30px;
      top: -42px;
      right: 30px;
      margin: 0 auto;
    }
  
    .dor-orr-block {
      padding: 20px 8px 20px 8px;
      /* max-width: 350px; */
    }
  
    .dor-block img, .orr-block img {
      margin-right: 5px;
      margin-top: -17px;
    }
    /*21-05*/
    .efficacy .orr-block img{
      position: relative;
      top: 9px;
  }
    /*21-05*/
  .orr-block{
    margin-bottom:-10px;
  }
    .dor-block, .orr-block {
      align-items: center;
    }
  
    .dor-orr-block .btm-list {
      margin: 20px auto;
      margin-bottom: 5px !important;
      max-width: 300px;
    }
  
    .meta-chemo-efficacy .sensitivity-table-container ul.bullet-list {
      text-align: left;
    }
    .meta-chemo-efficacy #section-5 .page-section-inner {
        padding: 0 20px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-3 ul.bullet-list.align-after-panel-chemo.forestPlotBullet {
      margin-left: 25px !important;
    }
    .desk-only{
      display:none;
    }
    #with-cns img,#without-cns img {
      padding: 0!important;
    }
  
    #without-cns img {
      margin-top: 8px;
    }
  
    .sensitivity-table-container ul.bullet-list li:before {
      position: absolute;
      left: -10px;
    }
  
    .efficacy.metastatic-nsclc #pfs {
          /*padding: 0 10px;*/
      ;
    }
        
        
    
      /****81422*****/
  }
  
  @media screen and (min-width: 992px) {
      .EGFR-mutation-type-inner .EGFR-heading{
      padding:0 10px;
        max-width: fit-content !important;
    }
    #cns-data > div.page-section-inner.container > div:nth-child(7) > div > div > div.copy-content > span.extrabold.copy-content-lg.surviva-txt{
      font-size:24px;
    }
    #cns-data > div.page-section-inner.container > div:nth-child(7) > div > div > div.copy-content > span.ffb-sb.copy-content-med-new.chemo-chart-txt-med.chemo-chart-txt-height{
      /* padding-right: 23px; */
    }
    #cns-data > div.page-section-inner.container > div:nth-child(7) > div > div{
      padding: 4px 0 10px 0;
    }
    #cns-data > div.page-section-inner.container > div:nth-child(4) > div > ul > li:nth-child(2){
      margin-top:10px;
    }
  #pfs > div.page-section-inner.container > div:nth-child(14) > div > div.nccn-block.desktop-only.slide-into.is-visible > div.polygon.poly-e.slide-frm-left{
    height: 118px;
  }
    #pfs > div.page-section-inner.container > div:nth-child(14) > div > div.nccn-block.desktop-only.slide-into.is-visible > div.nccn-content.sm-nccn-content.mn-nccn-content.slide-frm-right > p{
      margin:0;
    }
    .metastatic-nsclc .polygon {
      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/global/nccn-chevron-desktop-1.png) no-repeat;
      background-size: 100% 100%;
      width: 160px;
      min-width: 160px;
      height: 90px;
    }
      .metastatic-nsclc .polygon p {
    height: 100%;
    text-align: center;
    vertical-align: middle;
    color: #ffffff;
    font-weight: 500;
    margin-top: 0;
    padding-right: 4px;
    margin-bottom: 0;
    display: flex;
    justify-content: center;
    align-items: center;
    line-height: normal;
    font-family: 'Barlow';
    font-weight: 600;
    font-size: 16px;
  }
      
    .orr-copy {
      width: 80%;
      margin-left: auto !important;
      margin-right: auto !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-line {
      margin-top: 0px;
      border-top: 0;
      height: 300px;
    }
  
    .meta-chemotherapy .box-center.txt-ctr ul.bullet-list {
      margin-bottom: -10px;
  max-width: 73% !important;
      margin-left: auto !important;
    }
      
      /****81422*****/
      
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-one,.meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-two {
      height: 82px;
      min-width: 580px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .is-visible .hor-bar-two {
      min-width: 415px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-one p {
      top: 23px;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .hor-bar-two.hor-bar p {
      top: 23px;
    }
    
    
      
      
      /****81422*****/
      
    .meta-chemo-efficacy.metastatic-nsclc .section-2 p.tab-title {
      margin-bottom: 0px;
      font-size: 15px;
    }
  
    h2.unpre-median.first-line {
      margin-top: 5px !important;
    }
  
    .section-9 h2.unpre-median.first-line {
      margin-top: 50px !important;
      padding: 0;
    }
  
    .fn_1 {
      text-indent: -5px;
    }
     .metastatic-efficacy ul.bullet-list.no-margin-btm li::before{
          left: -7px;
    }
    #pfs > div.page-section-inner.container > div:nth-child(16) > div > div > ul > li:before{
      left: 2px;
    }
  
    .footnotes.fn_2 {
      text-indent: -5px;
    }
  
    .fn_3 {
      text-indent: -3px;
      padding-left: 6px;
    }
  
    .ml_4 {
      margin-left: 4px;
    }
  
    .efficacy .footnotes.mtop_10.nccn-footnotes {
      text-indent: -4px;
    }
  
    .efficacy.resectable-nsclc #subgroups .panel-group {
      margin-left: -10px;
    }
  
    .efficacy.resectable-nsclc .section-1 .km-curve {
      right: 2px;
    }
  
    img.stage-61 {
      max-width: 135px;
      top: 10px;
    }
  
    .efficacy.resectable-nsclc .section-1 .dfs-copy p.purple-txt.extrabold {
      position: relative;
      top: -4px!important;
      font: normal bold 78px/20px Barlow !important;
      letter-spacing: -0.38px!important;
    }
  
    .efficacy .flex-2-box {
            /*margin-left: 24px;*/
      margin-left: 14px;
      position: relative;
      left: -2px;
    }
  
    .section-3 .accordion-container .collapse-panel-heading .fa {
      top: 0px;
    }
  
    .efficacy .mobile-only-1 {
      display: none;
    }
  
    .copy-content {
      width: 100%;
    }
  
    .copy-per {
      max-width: 136px;
      width: 100%;
      margin: 10px 0 0 40px;
      background-size: contain;
      padding: 0;
    }
  
    .copy-per p {
      line-height: 83px !important;
      padding: 0 !important;
      margin: 0 !important;
      text-align: center;
    }
  
    .metastatic-nsclc .section-1 .copy-per {
      width: 100%;
      padding: 9px 2px 0px 0;
      min-height: 95px;
      background-size: contain;
      height: 95px;
      margin-bottom: 10px;
      margin-left: 50px;
    }
  
    .resectable-nsclc .section-1 p.nccn-content {
      height: 106px;
      padding-top: 22px;
    }
  
    .efficacy.resectable-nsclc .section-1 p.nccn-content {
      height: 90px;
      padding-top: 22px;
    }
  
    .isi-wrapper.open {
      margin-top: 0px;
    }
  
    .metastatic-nsclc .section-9 .visit-btn a {
      padding: 9px 0;
      padding-right: 67px;
      padding-left: 67px;
      padding-top: 8px;
    }
  
    .efficacy #eff-ex-txt-fix-d, .efficacy #eff-ex-txt-fix-c {
      font-weight: 400;
    }
  
    .section-1 .nccn-block {
      margin-left: auto;
      margin-right: auto;
      width: 736px;
    }
  
    img.adjuvant-chart.desktop-only {
      max-width: 820px;
      height: 220px;
    }
  
    .section-2 .green-banner p {
      padding-left: 5px;
      font-weight: 600;
    }
  
    .section-4 .new-image.table-text.graphic-image {
      padding-top: 4px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
      left: 25px;
      margin: 27px auto 58px;
    }
  
    .metastatic-nsclc .section-6 .bar-chart-horizontal {
      position: relative;
      left: 115px;
    }
  
    .efficacy .heading-block .line-2 {
      margin: 6px 0px;
    }
  
    #dfs .copy-content {
      margin-top: 22px;
      width: 100%;
    }
  
    .efficacy .accordion.section .accordion-container .az-panel-title p {
      padding-bottom: 11px;
      text-align: left;
      /* padding-left:22px!important; */
      padding: 10px 0 11px 15px;
    }
  
    .metastatic-efficacy .section-1 .data-copy .copy-per p {
      padding: 20px 0 12px 0px;
      font-size: 63px !important;
      font-weight: 700 !important;
      left: 4px;
      top: 2px;
      line-height: 19px !important;
      padding-top: 18px !important;
      position: relative;
    }
    
    .metastatic-efficacy .section-1 .data-copy.two-text .copy-per p {
                padding-top: 14px !important;
                left: 1px;
    }
    
    
    #pfs > div.page-section-inner.container > div:nth-child(8) > div > div > div.copy-per.chevron-down > p{
          left: 7px;
          top: 7px;
    }
      .metastatic-efficacy .section-1 .data-copy .copy-per.second p {
          padding-top: 23px !important;
      padding-left: 13px !important;
    }
  
    .metastatic-nsclc .section-1 .nccn-footnotes {
      margin-top: 14px;
      margin-left: 55px;
    }
  
    .metastatic-nsclc #os .panel-body img {
      margin-top: 10px;
    }
  
    .metastatic-nsclc .section-9 .customTable td:nth-child(1), .metastatic-nsclc .section-9 .customTable th:nth-child(1) {
      padding-left: 20px !important;
    }
  
    .adaura-box img {
      left: 15px;
      position: relative;
      max-width: 166px;
      height: 106px;
    }
  
    .column-2 .adaura-box img {
      max-width: 229px;
    }
  
    .metastatic-nsclc .section-9 .customTable th:nth-child(2) {
      text-align: center !important;
    }
  
    .resect-efficacy .section-10 .hor-bar-one, .resect-efficacy .section-10 .hor-bar-two {
      left: 93px !important;
      z-index: 6;
      opacity: 0;
    }
  
    .section-4 .new-image.table-text.graphic-image {
      width: 688px;
      margin: -11px auto 0;
    }
  
    p.tab-title.center-txt {
      max-width: 362px;
      margin: 0 auto;
      position: relative;
      left: -40px;
    }
  
    .box-3 {
      transform: translateY(145px);
      transition: 2s ease-in-out;
    }
  
    .box-2 {
      transform: translateY(100px);
      transition: 1.7s ease-in-out;
    }
  
    .box-1 {
      transform: translateY(85px);
      transition: 1s ease-in-out;
    }
  
    .is-visible .rtt-section {
      transform: none;
    }
  #pfs > div.page-section-inner.container > div:nth-child(15) > div > div.nccn-block.desktop-only.slide-into.is-visible > div.nccn-content.sm-nccn-content.mn-nccn-content.slide-frm-right > p{
    margin-bottom:0;
  }#pfs > div.page-section-inner.container > div:nth-child(15) > div > div.nccn-block.desktop-only.slide-into.is-visible > div.polygon.poly-e.slide-frm-left{
    height: 118px;
  }
    .purple-txt.ffb-med,.top-content .ffb-med,
    .bottom-content .ffb-med {
      line-height: 18px !important;
      padding-top: 0px;
    }
    
    /* update start */
    p.nccn-content.nccn-lg.purple-txt.ffb-med.nccn-copy.grey-bg.slide-frm-right.nccn-eff-badge-fix-1 {
      padding: 7px 10px 7px 13px;
      line-height: 15px !important;
      margin-left: 10px;
    }
  
    #eff-mobile-chart-brain-graphic {
      width: 720px;
      /*padding-bottom: 40px;*/
      padding-bottom: 20px;
    }
  
    .resec-span-desktop-only {
      white-space: nowrap;
    }
  
    div#efficacy-2x-banner-fix-a {
      /*margin: 12px 0px 0px 100px !important;*/
      margin: 17px 0px 0px 100px !important;
    }
  
    p#efficacy-2x-banner-fix-00 {
      margin-bottom: 24px;
    }
  
    span#efficacy-2x-banner-fix-01 {
      font-size: 38px;
    }
  
    span#efficacy-2x-banner-fix-02 {
      font-size: 22px;
      color: #5B305D;
    }
  
    span#efficacy-2x-banner-fix-03 {
      font-size: 18px;
    }
  
    span#efficacy-2x-banner-fix-04 {
      font-weight: 300;
    }
  
    .efficacy.resectable-nsclc .section-15 .box-2 .treat-dna-icon {
      width: 95px !important;
      height: auto !important;
      position: relative;
      top: -4px;
    }
  
    .section-15 h2.consistent-dfs {
      margin: 55px 0 45px 0 !important;
    }
  
    p.subhead.extrabold.icon-head.eff-icon-height-fix-a {
      line-height: 10px !important;
    }
  
    div#eff-rtt-fix-a {
      margin: 45px auto 20px !important;
    }
  
    ul#eff-bullet-rethink-fix {
      margin-left: -25px;
    }
  
    #eff-bullet-rethink-fix > li::marker {
      color: #008995;
    }
  
    p#eff-margin-rethink-a {
      margin-top: 15px;
      margin-bottom: 15px;
    }
  
    #eff-table-height-fix-a td, #eff-table-height-fix-a th {
      line-height: 25px !important;
    }
  
    .efficacy.resectable-nsclc .section-4 .subhead3 {
      margin: 68px 0 42px 0px !important;
    }
  
    p#eff-stage-box-copy-a {
      font-size: 14px;
      position: relative;
      top: -8px;
      left: 18px;
    }
  
    img#eff-stage-box-graphic-a {
      max-width: 140px;
      position: relative;
      top: -4px;
      left: 42px;
    }
  
    span#eff-stage-box-copy-b {
      font-size: 34px;
    }
  
    span#eff-stage-box-copy-c {
      font-size: 24px;
    }
  
    h2#margin-eff-dfs-a {
      margin-top: 90px;
    }
  
    .efficacy.resectable-nsclc.resect-efficacy h2#margin-eff-dfs-a {
      margin-top: 45px;
    }
  
    div#eff-nccn-block-margin-b {
      margin: 40px auto;
    }
  
    p#surgeon-subhead-margin-b {
      margin-top: 70px;
    }
  
    div#eff-teal-banner-btm {
      margin-bottom: 60px;
    }
  
    #adaura-desktop-table-a td:nth-child(1), #adaura-desktop-table-a th:nth-child(1) {
      padding: 0px 30px !important;
      padding-left: 16px!important;
    }
  
    #adaura-desktop-table-a tr:nth-child(3) td:nth-child(1), #adaura-desktop-table-a tr:nth-child(4) td:nth-child(1), #adaura-desktop-table-a tr:nth-child(5) td:nth-child(1), 
    #adaura-desktop-table-a tr:nth-child(7) td:nth-child(1), #adaura-desktop-table-a tr:nth-child(8) td:nth-child(1), #adaura-desktop-table-a tr:nth-child(9) td:nth-child(1) {
      padding-left: 30px!important;
    }
    
    
    /*update end */
    #section-13 .nccn-copy.grey-bg, #dfs .nccn-copy.grey-bg {
      height: 90px;
    }
  
    #eff-badge-fix-0 {
      height: 90px;
      margin-left: 11px;
    }
  
    #eff-badge-img-fix-0 {
      width: 162px!important;
      position: relative;
      top: -4px;
    }
  
    #eff-badge-img-fix-1 {
      width: 166px!important;
      position: relative;
      top: -3px;
      left: -3px;
    }
  
    .tp-disclaimer {
        /*text-align: center;*/
      text-indent: 0;
    }
  
    .efficacy.metastatic-nsclc.metastatic-efficacy .section-1 .copy-content {
        /*margin-top: 15px;*/
        margin-bottom: 8px;
        margin-top: 28px;
    }
  
    .metastatic-nsclc .copy-content-med-new {
      font-size: 15px;
      line-height: 17px;
    }
  
    .metastatic-nsclc .vs-txt-new {
      font-size: 14px;
      /* line-height: 10px; */
      margin-top: -3px;
      display: block;
    }
  
    .metastatic-nsclc span.d-block {
      display: block;
      margin-top: -3px;
    }
  
    .progression-survival-graph img {
      margin-left: 25px;
    }
  
    .cns-progression-graph img {
      margin: 5px 0 15px 0;
      width: 102% !important;
      position: relative;
      right: 5px;
    }
  }
  
  .accordion-group.panel .panel-body {
    padding-top: 20px;
  }
  
  #pfs .accordion-group.panel .panel-body {
    padding-top: 5px;
      /*padding-top: 0px;*/
    ;
  }
  
  #subgroups .accordion-group.panel .panel-body {
    padding-left: 0;
    padding-right: 0;
    padding-bottom: 5px;
  }
  
  .section-3 .accordion-group.panel .panel-body {
    padding-top: 12px;
  }
  
  .percentage-patient {
    position: relative;
    top: -18px;
    line-height: 18px !important;
    color: #262626;
  }
  
  .metastatic-efficacy #flaura .flaura-section img {
    max-width: 800px;
    margin: 0 auto;
  }
    
    /***********************dfs******************/
  .efficacy.resectable-nsclc .section-4 .final-analysis-link .final-analysis-text a, .efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text a,
    .efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text a {
    font: normal normal 700 21px/26px Barlow !important;
  }
  
  .efficacy.resectable-nsclc .section-4 .final-analysis-link .final-analysis-text, .efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text,
    .efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/final-analysis-bg.png) no-repeat;
    padding: 17px 30px 32px 21px;
  }
  
  .final-analysis-link .final-analysis-text {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/final-analysis-bg.svg) no-repeat;
    padding: 25px 28px 32px;
  }
  
  .efficacy .subgroup-header-part .subgroup-head p {
    margin: 90px 0 16px 0;
  }
  
  .efficacy ul.median-list-3 {
    margin-top: 22px;
    margin-bottom: 0;
  }
  
  .efficacy .space-t-18 {
    padding: 18px 0 18px 0!important;
    font-weight: 600;
  }
  
  .efficacy .subgroup-header-part .subgroup-head h2 {
    margin-bottom: 42px;
  }
  
  .efficacy.resectable-nsclc .section-7 .final-analysis-link .final-analysis-text, .efficacy.resectable-nsclc .section-10 .final-analysis-link .final-analysis-text {
    display: none;
  }
  
  .metastatic-nsclc .section-2 .copy-content {
    margin: 35px 0 17px 12px;
  }
  
  .metastatic-nsclc .section-6 .data-copy .copy-per {
    padding-left: 10px;
  }
  
  .metastatic-nsclc .section-6 .data-copy .copy-content {
    margin-top: 22px;
  }
  
  .subgroup-header-part, .with-chemo {
    display: flex;
    position: relative;
    align-items: center;
  }
  
  .efficacy.resectable-nsclc .section-10 .img-small-txt {
    display: inline;
    font-size: 16px;
    margin: 6px 0 0 0px;
    line-height: 21px;
  }
  
  .efficacy.resectable-nsclc .section-10 .copy-txt {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/76-purple-shape.svg);
    background-repeat: no-repeat;
    background-size: 100%;
      /*max-width: 675px;*/
    max-width: 770px;
    font-size: 18px;
    line-height: 21px !important;
    padding: 10px 0 0 48px;
  }
  
  .efficacy.resectable-nsclc .section-10 .lg-txt {
    font-size: 62px;
    line-height: 19px;
    width: 18%;
      /*padding: 16px 0 0 25px;*/
    padding: 16px 0 0 16px;
    height: 55px;
  }
  
  .efficacy.resectable-nsclc .section-10 .brain-section .cns-text {
    position: relative;
    display: block;
    margin-top: 2px;
  }
  
  .efficacy.resectable-nsclc .section-4 .eyebrow {
    margin: 65px 0 10px 0;
  }
  
  .efficacy.resectable-nsclc #with-without-chemo .final-analysis-link {
    top: 44px;
  }
  
  .efficacy.resectable-nsclc .final-analysis-link {
    right: -30px;
    margin-top: -30px;
  }
  
  .efficacy.resectable-nsclc .section-4 .stage61-chart .copy-content-lg,
    .efficacy.resectable-nsclc .section-4 .stage-61-text .txt-md, .efficacy.resectable-nsclc .section-1 .copy-content-sm {
    line-height: 27px !important;
  }
  
  .efficacy.resectable-nsclc .stage61-chart .hr-txt, 
    .efficacy.resectable-nsclc .section-4 .stage-61-text .copy-content-sm {
    line-height: 17px !important;
  }
  
  .efficacy.resectable-nsclc .copy-per.hr-image {
    min-height: 113px !important;
    transform: none;
    padding-top: 11px;
  }
  
  .efficacy.resectable-nsclc p.prior-per {
    margin-top: -23px;
    margin-bottom: 15px;
  }
  
  .efficacy.resectable-nsclc .section-10 .brain-section {
    margin: 0 11px 44px 0;
    justify-content: center;
  }
  
  .efficacy.resectable-nsclc #cns .refer-section {
    max-width: 629px;
    margin: 0 auto;
  }
  
  .efficacy.resectable-nsclc .section-1 .eyebrow {
    line-height: 26px !important;
  }
  
  .efficacy.resectable-nsclc .section-1 h1.new-data {
    font: normal normal 800 75px/90px Barlow;
    letter-spacing: 0px;
    text-transform: uppercase;
    margin: 0;
    color: #5B305D;
  }
  
  .efficacy.resectable-nsclc .section-1 .egfr-mutation.new-datatwo {
    letter-spacing: 0px;
    font-size: 36.5px;
    line-height: 66px;
    font-weight: 500;
    margin: -20px 0 0 0;
    color: #5B305D;
  }
  
  .efficacy.resectable-nsclc .section-1 h2.egfr-mutation.analysis-text {
    box-shadow: inset 0px 2px 3px #00000029;
    border: 2px solid #CEDB00;
    border-radius: 14px;
    opacity: 1;
    max-width: 710px;
    margin: 0 auto;
    font: normal normal 800 25px/24px Barlow;
    letter-spacing: 0px;
    color: #5B305D;
    margin-top: 30px;
    padding: 15px 0px 15px;
  }
  
  .efficacy.resectable-nsclc .section-1 p.subhead.finaldfsdata {
    font: normal normal 800 25px/26px Barlow;
    letter-spacing: 0px;
    color: #5B305D;
    text-transform: uppercase;
    border-top: 2px solid #5B305D;
    padding-top: 30px;
    max-width: 710px;
    margin: 0 auto;
    margin-top: 33px;
  }
  
  .efficacy.resectable-nsclc .section-1 p.bracket-text {
    font: normal normal normal 18px/26px Barlow;
    letter-spacing: 0px;
    color: #5B305D;
    padding-top: 5px;
    margin-bottom: 25px;
  }
  
  .efficacy.resectable-nsclc .section-1 .eyebrow.dfs-eyebrow {
    letter-spacing: 0px;
    color: #5B305D;
    font-size: 16px;
    line-height: 24px !important;
    font-weight: normal;
    max-width: 560px;
    display: block;
    margin: 4px auto 0;
  }
  
  .efficacy.resectable-nsclc #cns.section-10 .final-analysis-link {
    position: absolute;
    display: block;
    top: 105px;
    right: -85px;
  }
  
  .efficacy.resectable-nsclc .section-1 .copy-per {
    margin: 8px 0 0 48px;
  }
  
  .efficacy.resectable-nsclc .section-1 .dfs-content .copy-content-lg {
    line-height: 25px !important;
  }
  
  .efficacy.resectable-nsclc .section-1 .dfs-copy p.purple-txt.extrabold {
    text-align: center;
    font: normal bold 78px/20px Barlow;
    letter-spacing: -0.38px;
    color: #5B305D;
      /* padding-top: 19px !important; */
    display: flex;
    height: 100%;
    align-items: center;
    justify-content: center;
    position: relative;
    top: -4px;
  }
  
  .efficacy.resectable-nsclc .section-1 .copy-content-med {
    font-size: 20px;
    line-height: 25px !important;
    letter-spacing: 0px;
    color: #333333;
    display: block;
    margin-top: -2px;
  }
  
  .efficacy .median-list li {
    margin-bottom: 14px;
    max-width: 784px;
  }
  
  .efficacy.resectable-nsclc .section-1 .copy-content-med sup {
    top: -0.6em;
    font-size: 62%;
  }
  
  .efficacy.resectable-nsclc .section-1 .copy-per .copy-content-lg.yr-txt {
    font-size: 27px;
    line-height: 20px;
    letter-spacing: -0.16px;
  }
  
  .efficacy.resectable-nsclc .section-1 .copy-content-sm .percentage-text {
    font-weight: 500;
    color: #5A5B5E;
  }
  
  .efficacy.resectable-nsclc .section-1 .accordion.section, .efficacy.resectable-nsclc .section-1 .data-copy {
    max-width: 710px;
  }
  
  .efficacy.resectable-nsclc .section-1 .accordion-group.panel .panel-body {
    padding-top: 21px;
    padding-bottom: 15px;
  }
  
  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content {
    max-width: 497px;
    margin: 50px auto 37px auto;
  }
  
  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box {
    padding: 0;
    min-height: 245px;
    display: none;
  }
  
  .efficacy.resectable-nsclc .dfs-content-box {
    position: relative;
    border: 2px solid #9B9B9B;
    border-radius: 20px;
    padding: 55px 0 30px 0;
    margin: 75px auto 40px auto;
    max-width: 650px;
  }
  
  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box .abs-top {
    background: #fff;
  }
  
  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .dfs-content-box .subhead {
    position: absolute;
    top: -34px;
    width: 60%;
    left: 0;
    right: 0;
    margin: 0 auto;
    letter-spacing: -0.09px;
  }
  
  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li .tab-row4 sup,  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li .tab-row1 sup {
    top: -13px;
  }
  
  .efficacy.resectable-nsclc .section-1 .newsection-content .dfs-content-box ul {
    margin: 32px 10px 5px 37px;
    padding: 0;
    padding-bottom: 10px;
  }
  
  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li {
    display: inline-block;
    list-style: none;
    width: 32%;
    margin-left: -4px;
    text-align: center;
    padding: 0;
  }
  
  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul li span {
    display: block;
  }
  
  .efficacy.resectable-nsclc .section-1 .newsection-content span.tab-head {
    font: 700 17px/20px Barlow;
    letter-spacing: -0.58px;
    color: #4E5055;
    text-transform: uppercase;
    border-bottom: 1px solid #707070;
    padding-bottom: 7px;
    padding-left: 0px;
    padding-top: 8px;
  }
  
  .newsection-content span.tab-row1, .newsection-content span.tab-row4 {
    position: relative;
  }
  
  .newsection-content span.tab-row1 {
    font: 700 40px/48px Barlow;
    letter-spacing: 0px;
    color: #5B305D;
    margin-top: 3px;
  }
  
  .newsection-content span.tab-row3 {
    width: 46px;
    height: 8px;
    opacity: 1;
    border-radius: 50%;
    text-align: center;
    display: block;
    margin: 1px auto 9px auto;
    position: relative;
    left: 1px;
    top: -1px;
  }
  
  .newsection-content span.tab-row1, .newsection-content span.tab-row4 {
    margin-left: 10px;
  }
  
  .newsection-content span.tab-row3 {
    margin: 4px auto 12px auto;
  }
  
  .newsection-content span.tab-row4 {
    font: normal normal normal 40px/48px Barlow;
    letter-spacing: 0.44px;
    color: #4E5055;
    top: -3px;
  }
  
  .newsection-content span.tab-row2 {
    font-weight: 600 !important;
    margin-top: -4px;
  }
  
  .newsection-content span.tab-row2,
    .newsection-content span.tab-row5 {
    font: normal normal normal 13px/16px Barlow;
    letter-spacing: -0.33px;
    color: #4E5055;
  }
  
  .newsection-content li.years-2, .newsection-content li.years-3 {
    border-right: 1px solid #707070;
  }
  
  .efficacy.resectable-nsclc .section-1 .subhead.median-text {
    text-align: left;
    max-width: 712px;
    margin: 0 auto;
    letter-spacing: -0.09px;
  }
  
  .efficacy .green-banner.ma-top-70 {
    margin-top: 70px!important;
  }
  
  .efficacy .fn-dfs {
    max-width: 792px;
  }
  
  .efficacy .nccn-bl-footnotes .footnotes {
    padding-left: 0;
    max-width: 736px;
    margin-left: 36px;
  }
  
  .efficacy.resectable-nsclc .section-1 .nccn-block {
    margin: 21px auto 0 auto;
    max-width: 736px;
    margin-top: 54px;
    margin-left: 36px;
  }
  
  .resectable-nsclc .section-1 p.nccn-content {
    line-height: 20px !important;
    margin-bottom: 3px;
    padding: 22px 26px 15px 20px;
  }
  
  .efficacy.resectable-nsclc .section-1 p.nccn-content {
    line-height: 19px !important;
    margin-bottom: 0px;
    padding: 8px 19px 4px 19px;
    margin-left: 14px;
  }
  
  .efficacy.resectable-nsclc .section-1 .nccn-lg.grey-bg:before {
      /*height: 106px;*/
    height: 90px;
  }
  
  .efficacy img.nccn-badge {
    width: 162px!important;
  }
  
  .is-visible .green-banner {
    transform: translateX(-47px);
  }
  
  .green-banner p {
    padding-left: 0px !important;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-line {
    width: 633px;
    margin-top: 10px;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-ruler {
    width: 17.4%;
  }
  
  .efficacy.resectable-nsclc .section-10 ul.hor-scale {
    left: 93px;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar-container .left-bar-data2 {
    left: -15px;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar-container .left-bar-data1 {
    left: -5px;
  }
  
  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one.hor-bar {
    min-width: 161px;
  }
  
  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second.hor-bar {
    min-width: 130px;
  }
  
  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two-second.hor-bar {
    min-width: 240px;
  }
  
  .efficacy.resectable-nsclc .hor-bar-one-second {
    margin: 0 0 28px 0;
    left: 254px !important;
  }
  
  .efficacy.resectable-nsclc .hor-bar-two-second {
    left: 499px;
    margin: 0 0 32px 0;
  }
  
  .efficacy.resectable-nsclc .section-4 .subgroup-head .subhead {
    margin: 38px 0 32px 0;
    font-size: min(1.97vw,22px);
  }
  
  .efficacy.resectable-nsclc .section-4 .accordion-group.panel .panel-body {
    padding-top: 23px;
  }
  
  .efficacy.resectable-nsclc .section-4 .new-image.table-text.graphic-image {
      /*width: 664px;*/
      /*height: 487px;*/
      /*    width: 679px;*/
      /*height: 469px;*/
      /*margin: 0px auto;*/
          /* width: 664px; */
        /* height: 487px; */
    width: 665px;
    height: 470px;
    margin: 0px auto;
  }
  
  .efficacy.resectable-nsclc .section-13 .patient-img.tab-title img {
    height: 410px;
  }
  
  .efficacy .with-chemo-head p.eyebrow {
    margin: 0!important;
  }
  
  .efficacy.resectable-nsclc .section-1 .km-curve {
      /*width: 680px;*/
      /*height: 304px;*/
    width: 671px;
    height: 438px;
    right: 0px;
    top: -10px;
  }
  
  .efficacy.resectable-nsclc .section-4 .subhead3 {
      /*margin: 55px 0 16px 0;*/
    margin: 78px 0 42px 0px;
  }
  
  .efficacy.resectable-nsclc .section-5 .green-banner {
    margin: 55px 0 55px 0;
  }
  
  .efficacy.resectable-nsclc .section-6 .last-footnote {
    margin: 0 0 42px 0;
  }
  
  .efficacy.resectable-nsclc .section-7 .eyebrow {
    margin: 66px 0 0 0;
  }
  
  .efficacy.resectable-nsclc .section-7 .adaura-km-chart {
    margin: 23px 0 0 0;
  }
  
  .efficacy.resectable-nsclc .updated-copy-hr {
    margin-bottom: 23px !important;
  }
  
  .efficacy.resectable-nsclc .section-9 .small-txt {
    margin-bottom: 30px;
  }
  
  .efficacy.resectable-nsclc .section-9 .last-footnote {
    margin: 0 0 68px 0;
  }
  
  .efficacy.resectable-nsclc .section-10 .eyebrow {
    margin: 70px 0 7px 0;
  }
  
  .efficacy.resectable-nsclc .section-10 h2 {
    margin: 0 0 18px 0;
    max-width: 830px;
  }
  
  .efficacy.resectable-nsclc .section-10 .last-footnote {
    margin: 0px 0 54px 0;
  }
  
  .efficacy.resectable-nsclc .section-10 .bullet-list {
    margin: 35px 0 25px 7px !important;
  }
  
  #margin-subbullet {
    margin: 0px 0px 0px 10px !important;
  }
  
  .efficacy.resectable-nsclc .section-10 .last-footnote.s-ten {
    margin: 0px 0 40px 0;
    font-weight: 600;
  }
  
  .efficacy.resectable-nsclc .section-5 .green-banner p {
    padding: 1px 0 3px 0;
    font-weight: 600;
  }
  
  .efficacy.resectable-nsclc .subgroup-header-part .consistent-dfs {
    margin-top: 0px;
    font-size: min(2.7vw,30px);
  }
  
  .efficacy.resectable-nsclc .brain-icon-efficacy {
    width: 119px;
    height: 118px;
  }
  
  .efficacy.resectable-nsclc .section-4 .accordion.section {
    max-width: 710px;
  }
  
  .efficacy.resectable-nsclc .section-4 .stage-61-text {
    margin: 20px 0 0 5px;
  }
  
  .efficacy.resectable-nsclc .with-chemo .consistent-dfs {
    margin-top: 8px;
  }
  
  .efficacy.resectable-nsclc .bar-chart-horizontal {
    left: 17px;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar .num-lg {
    font: normal normal 700 44px/17px Barlow;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar-one p b, 
    .efficacy.resectable-nsclc .section-10 .hor-bar-one-second p b {
    font: normal normal 400 15px/17px Barlow;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar-two p b, 
    .efficacy.resectable-nsclc .section-10 .hor-bar-two-second p b {
    font: normal normal 500 15px/17px Barlow;
  }
  
  .efficacy.resectable-nsclc .section-1 {
      /*border-top: 14px solid #CEDB00;*/
    border-top: 12px solid #CEDB00;
  }
  
  .efficacy .middle-body {
    margin-top: 40px;
    margin-left: -16px;
  }
  
  .efficacy.resectable-nsclc .section-4 .subhead2 {
    max-width: 92%;
  }
  
  .resectable-nsclc #with-without-chemo .copy-per {
    padding: 14px 6px 6px;
  }
  
  .efficacy.resectable-nsclc .section-15 .box-1 .egfrm-bubble {
    margin-bottom: -5px;
  }
  
  .efficacy .footnotes.mtop_10.nccn-footnotes {
    margin-top: 24px!important;
  }
  
  .efficacy-test-icon {
    width: 103px !important;
    height: auto !important;
  }
  
  @media screen and (min-width: 1600px) {
    .section-10 .hor-line {
      width: 567px;
    }
  }
  
  @media screen and (min-width: 320px) and (max-width: 335px) {
    .section-11 .accordion.section .accordion-container .az-panel-title p {
      padding: 16px 39px 16px 15px;
    }
  }
  
  @media screen and (min-width: 347px) and (max-width: 365px) {
    .section-4 .accordion.section .accordion-container .az-panel-title p {
      padding: 8px 38px 8px 15px;
    }
  }
  
  @media screen and (min-width: 414px) and (max-width: 992px) {
    .metastatic-nsclc.metastatic-efficacy .section-6 p.vertical-txt {
      left: 10px;
      font-size: 11px;
      line-height: 10px !important;
    }
  }
  
  @media screen and (min-width: 425px) and (max-width: 991px) {
    #dfs .panel-body img {
      margin: 0 auto;
    }
  }
  
  @media screen and (min-width: 640px) and (max-width: 767px) {
    .metastatic-nsclc .section-6 .brain-icon {
      left: 27px;
      top: -40px;
    }
  
    .metastatic-nsclc .section-6 .graphic-subhead {
      left: 90px;
      top: -45px;
      padding: 0 8px 0 68px;
      margin: 0;
    }
  }
  
  @media screen and (min-width: 768px) and (max-width: 991px) {
    table.adaura-staging-table th.purple-txt {
      padding: 0 20px;
    }
  
    .metastatic-nsclc .slide-into {
      display: flex;
      flex-direction: column;
    }
  
    .metastatic-nsclc .section-2 .pfs-center-block {
      justify-content: initial;
      min-width: 525px;
    }
  
    .metastatic-nsclc .section-6 .graphic-subhead {
      top: -35px;
      text-align: center;
    }
  
    .metastatic-nsclc .section-6 .brain-icon {
      left: 77px;
    }
    
    /*.metastatic-nsclc .section-6 ul.hor-scale {*/
    /*  left: 202px;*/
    /*}*/
    
    .resectable-nsclc .sect-6.txt-ctr {
      max-width: 330px;
      margin: 0 auto;
    }
  
    .resectable-nsclc .sect-6.txt-ctr .left-img {
      min-width: 110px;
    }
  
    p.or-txt:after {
      bottom: 17px;
    }
  
    .efficacy.resectable-nsclc p.or-txt:after {
      bottom: 32px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
      margin-left: auto;
    }
  
    .eff-demographic-chart table.adaura-staging-table th.purple-txt {
      padding: 0px 20px 10px;
      text-align: center;
    }
  
    .efficacy.resectable-nsclc .section-1 .km-curve .expand-img-mobile.visible-xs-inline-block,
    .efficacy.resectable-nsclc .section-1 .km-curve .new-image-mobile,
    .efficacy.resectable-nsclc .section-1 .new-image.seventythreeper .expand-img-mobile.visible-xs-inline-block, .efficacy.resectable-nsclc .new-image.seventythreeper,
    .efficacy.resectable-nsclc .section-1 .new-image.seventythreeper .new-image-mobile {
      display: block !important;
    }
  
    .efficacy.resectable-nsclc .section-1 .km-curve .expand-img-desktop.visible-sm-inline-block, .efficacy.resectable-nsclc .section-1 .km-curve .new-image-desktop,
    .efficacy.resectable-nsclc .section-1 .new-image.seventythreeper .expand-img-desktop.visible-sm-inline-block, 
    .efficacy.resectable-nsclc .section-1 .new-image.seventythreeper .new-image-desktop {
      display: none !important;
    }
  }
    
    /*.new-image-mobile {*/
    /*    margin-left: -52px;*/
    /*}*/
    
  @media screen and (min-width: 991px) and (max-width: 1024px) {
    .metastatic-nsclc .section-6 .is-visible .hor-bar-one,.metastatic-nsclc .section-6 .is-visible .hor-bar-two {
      left: 135px;
    }
  
    .efficacy.resectable-nsclc img.stage-61 {
      height: 95px;
      width: 135px;
    }
  }
  
  @media screen and (min-width: 768px) and (max-width: 1024px) {
    .efficacy.resectable-nsclc .new-image.seventythreeper {
      display: none;
    }
  }
  
  table.demographic-table tr:nth-child(8) td:first-child, table.demographic-table tr:nth-child(9) td:first-child {
    padding-left: 40px !important;
  }
  
  .metastatic-efficacy .section-6 .cns-progression-vertical-graph sup {
    top: -0.5em;
  }
  
  .metastatic-efficacy .section-1 .panel-body {
    padding: 0px;
  }
  
  sup.sup-twonum {
    top: -0.9em;
  }
  
  .efficacy.resectable-nsclc .final-analysis-link {
    position: relative;
    display: block;
  }
  
  .efficacy.resectable-nsclc .final-analysis-link .final-analysis-text a {
    color: #5B305D;
    font: normal normal 700 22px/26px Barlow !important;
    pointer-events: none;
  }
  
  .efficacy.resectable-nsclc .final-analysis-link .final-analysis-text {
    background-size: 100% 100%;
    display: inline-block;
    text-align: center;
  }
  
  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one.hor-bar,
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-one-second.hor-bar,
    .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two-second.hor-bar {
    opacity: 1;
  }
  
  .efficacy.resectable-nsclc .hor-bar-one-second {
    position: absolute;
    min-width: 0px;
    height: 92px;
    bottom: 186px;
    background: #937794;
    transition: 1s all ease;
    transition-delay: 1s;
    opacity: 0;
    z-index: 2;
  }
  
  .efficacy.resectable-nsclc .hor-bar-two-second {
    background: #AEB0B3;
    min-width: 0px;
    position: absolute;
    height: 92px;
    bottom: 68px;
    transition: 1s all ease;
    transition-delay: 1s;
    opacity: 0;
    z-index: 2;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar p, .efficacy.resectable-nsclc .hor-bar span, 
    .efficacy.resectable-nsclc .section-10 .hor-bar-two.hor-bar p {
    color: #ffffff;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar-one p, .efficacy.resectable-nsclc .section-10 .hor-bar-one-second p, 
    .efficacy.resectable-nsclc .section-10 .hor-bar-two-second p, .efficacy.resectable-nsclc .section-10 .hor-bar-two.hor-bar p {
    top: 26px;
    position: absolute;
    text-align: right;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar-one p {
    right: 20px;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar-one-second p, 
    .efficacy.resectable-nsclc .section-10 .hor-bar-two p {
    right: 15px;
  }
  
  .efficacy.resectable-nsclc .section-10 .hor-bar-two-second p {
    right: 18px;
  }
  
  .efficacy.resectable-nsclc .section-10 .is-visible .hor-bar-two {
    min-width: 406px;
    background: #555555;
    opacity: 1;
  }
  
  .efficacy.resectable-nsclc .updated-copy-hr {
    border: 2px solid #9B9B9B;
    border-radius: 14px;
    border-bottom: 2px solid #9B9B9B;
    border-top-left-radius: 0;
    border-top-right-radius: 0;
    background: #fff;
    margin-bottom: 10px;
  }
  
  .efficacy.resectable-nsclc .copy-per.hr-image {
    width: 100%;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/global/hr-box.png);
    background-repeat: no-repeat;
    margin: 0 auto;
    min-height: 94px;
    background-size: 100%;
    margin-bottom: 30px;
    max-width: 158px;
  }
  
  .efficacy.resectable-nsclc .updated-copy-hr p.purple-txt.ffb-b.lg-num {
    font: normal normal bold 60px/72px Barlow !important;
    letter-spacing: -0.36px;
    color: #5B305D;
    opacity: 1;
    text-align: center;
    margin-top: 4px !important;
  }
  
  .efficacy.resectable-nsclc p.prior-per {
    font: normal normal normal 15px/18px Barlow !important;
    letter-spacing: 0.38px;
    color: #333333;
    text-align: center;
  }
  
  .efficacy.resectable-nsclc .section-7 .adaura-km-chart .column-1:before {
    /*height: 279px;*/
    /*top: 0px;*/
    /*  right: -28px;*/
    height: 372px;
    top: 30px;
    right: -28px;
    display: none;
  }
  
  .efficacy.resectable-nsclc .section-7 .adaura-km-chart .column-1:after {
    /*top: 92px;*/
    /*height: 45px;*/
    /*line-height: 50px;*/
    /*right: -43px;*/
    /*  background: #f1f1f1;*/
    top: 122px;
    height: 50px;
    line-height: 50px;
    right: -43px;
    background: #f1f1f1;
    display: none;
  }
  
  .recurrence-cns-text .recurrence-left .check-box-one {
    background-color: #5B305D;
  }
  
  .recurrence-cns-text .recurrence-left .check-box-two {
    background-color: #555555;
  }
  
  .Local-regional-text .recurrence-left .check-box-one {
    background-color: #937794;
  }
  
  .Local-regional-text .recurrence-left .check-box-two {
    background-color: #A0A0A0;
  }
  
  .recurrence-right {
    margin-bottom: 10px;
  }
  
  .recurrence-left .check-box-one, .recurrence-left .check-box-two {
    width: 16px;
    height: 16px;
  }
  
  .recurrence-section {
    display: flex;
    align-items: center;
    justify-content: space-between;
    position: relative;
    width: 505px;
    margin: 0 auto;
  }
  
  .recurrence-cns-text, .Local-regional-text {
    display: flex;
    justify-content: space-between;
    position: relative;
    align-items: center;
    width: 212px;
  }
  
  .efficacy.resectable-nsclc .section-1 .accordion.section a.collapse-panel-heading {
    /*pointer-events: none;*/
    ;
  }
  
  .efficacy.resectable-nsclc .section-1 .dfs-accordian span.fa.pull-right.fa-minus {
    /*display: none;*/
    display: block;
  } 
    /*.efficacy.metastatic-nsclc .section-1 .accordion.section a.collapse-panel-heading,
    .efficacy.metastatic-nsclc .section-2 .accordion.section a.collapse-panel-heading,
    .efficacy.metastatic-nsclc .section-6 .accordion.section a.collapse-panel-heading,
    .efficacy.metastatic-nsclc .section-9 .accordion.section a.collapse-panel-heading {
    pointer-events: none;
    }
    .efficacy.metastatic-nsclc .section-1 .accordion.section span.fa.pull-right.fa-minus,
    .efficacy.metastatic-nsclc .section-2 .accordion.section span.fa.pull-right.fa-minus,
    .efficacy.metastatic-nsclc .section-6 .accordion.section span.fa.pull-right.fa-minus,
    .efficacy.metastatic-nsclc .section-9 .accordion.section span.fa.pull-right.fa-minus{
    display: none;
    }*/
    
  .efficacy.resectable-nsclc .section-1 .green-banner {
    margin: 50px 0 45px 0;
  }
  
  .efficacy.resectable-nsclc .section-2 .green-banner {
    margin: 58px 0 25px 0;
  }
  
  .efficacy.resectable-nsclc .section-3 .dfs-footnote {
    margin-bottom: 40px;
  }
  
  .efficacy.resectable-nsclc .section-10 ul.hor-scale {
    width: 100%;
  }
  
  .efficacy.resectable-nsclc .component-section.bg-white.section-1:before {
    box-shadow: 0px 2px 4px #00000045;
  }
    
    /*.resectable-nsclc .section-1 p.nccn-content .pink-var {*/
    /*  color: #E515DD !important;*/
    /*}*/
    
  .efficacy.resectable-nsclc .bg-grey.section-4:before, 
    .efficacy.resectable-nsclc .bg-grey.section-10:before,
    .efficacy.resectable-nsclc .bg-grey.section-6:after,
    .efficacy.resectable-nsclc .bg-grey.section-9:after,
    .efficacy.resectable-nsclc .bg-grey.section-15:after,
    .efficacy.resectable-nsclc .bg-grey.callout.adaura-callout:after {
    content: "";
    width: 100%;
    height: 3px;
    position: absolute;
    top: auto;
    box-shadow: 0px 0 20px rgb(0 0 0 / 25%);
    background: transparent;
  }
  
  .efficacy.resectable-nsclc sup {
    font-size: 60%;
    top: -0.6em;
  }
  
  .efficacy.resectable-nsclc .section-4 .stage-61-text .copy-content-sm {
    letter-spacing: 0.35px;
  }
  
  .efficacy.resectable-nsclc .section-7 .column-1 .adaura-copy {
    max-width: 120px;
    padding-right: 0px;
  }
  
  .newsection-content span.tab-row5 {
    margin-top: -8px;
    margin-bottom: 18px;
  }
  
  .efficacy.resectable-nsclc .updated-copy-hr p.purple-txt.ffb-b.lg-num {
    padding: 8px 0 0 !important;
  }
  
  .efficacy.resectable-nsclc .footnotes {
    text-indent: -3px;
  }
  
  p#eff-footnote-margin-a {
    margin-top: 40px;
  }
  
  .stage61-chart .footnotes {
    left: -9px;
  }
  
  .dfs-footnote p.footnotes.first-footnote {
    text-indent: -5px;
  }
  
  .efficacy.resectable-nsclc .section-15 .box-1 .egfrm-bubble {
    width: 95px;
    height: 103px;
  }
  
  .efficacy.resectable-nsclc .section-15 .box-2 .treat-dna-icon {
    width: 106px;
    height: 106px;
  }
  
  .efficacy.resectable-nsclc .section-15 .box-3 .az-280-treat-and-bottle-icon {
    width: 93px;
    height: 94px;
  }
  
  @media screen and (min-width: 1365px) {
    .efficacy.resectable-nsclc .subgroup-header-part .consistent-dfs,
    .efficacy.resectable-nsclc .with-chemo .consistent-dfs {
      width: 710px;
    }
  }
  
  @media screen and (min-width: 320px) and (max-width: 361px) {
    .efficacy.resectable-nsclc .section-1 .newsection-content .dfs-content-box .abs-top {
      top: -55px;
    }
  }
  
  @media screen and (min-width: 320px) and (max-width: 374px) {
    div#subgroups .panel-body img {
      max-width: 280px;
    }
  
    .surgery-and-treat-icon.mobile-only, .surgery-chemo-treat-icon.mobile-only {
      position: relative;
      top: 15px;
      max-width: 150px;
      height: 69px;
    }
  
    .efficacy.resectable-nsclc .section-10.btm-shadow span.ffb-b.cns-text {
      margin-right: 20px;
    }
  
    .metastatic-nsclc #efficacysubgroups .accordion.section .accordion-container .az-panel-title p {
      font-size: 13px;
    }
  }
  
  @media screen and (min-width: 413px) and (max-width: 768px) {
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
      margin-left: auto;
    }
  }
  
  @media screen and (min-width: 320px) and (max-width: 355px) {
    .metastatic-nsclc .section-1 .callout-box p {
      padding: 0px 0 0 6px;
    }
  
    .metastatic-nsclc .section-1 .callout-box .vs-txt {
      padding: 0 0 26px 10px;
    }
  
    .efficacy.resectable-nsclc .section-10.btm-shadow span.ffb-b.cns-text {
      font-size: 14px;
    }
  }
  
  @media screen and (min-width: 320px) and (max-width: 373px) {
    .metastatic-nsclc .section-6 .graphic-box {
      margin: 135px auto 63px auto;
    }
  
    .metastatic-nsclc .section-6 .graphic-subhead {
      top: -120px;
      padding-left: 30px;
    }
  }
  
  @media screen and (min-width: 320px) and (max-width: 357px) {
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
      left: 17px;
    }
  
    .metastatic-nsclc .section-6 .cns-progression-vertical-graph {
      margin-left: 15px;
    }
  
    .metastatic-nsclc .section-6 ul.hor-scale {
      max-width: 326px;
    }
  
    .cns-aura3-vertical-graph {
      max-width: 315px;
      left: 19px;
      /* overflow: hidden; */
      margin-left: 20px;
    }
  
    hr.ver-line {
      height: 179px;
      width: 245px;
    }
  
    .metastatic-nsclc .section-6 ul.hor-scale {
      max-width: 266px;
      left: -45px;
    }
  
    .metastatic-nsclc .section-6 .hor-ruler {
      width: 51px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-one {
      width: 80px;
      height: 74px;
      left: 25px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-two {
      width: 206px;
      height: 74px;
      left: 25px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data2 {
      bottom: 48px;
      left: -29px;
    }
  
    .metastatic-nsclc .section-6 .hor-line {
      width: 87%;
      left: 6px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
      left: -26px;
    }
  
    .metastatic-nsclc .section-6 .hor-bar-container .left-bar-data1 {
      font-size: 10px;
    }
  
    .block3 {
      display: flex;
      max-width: 311px;
    }
  
    .img1 {
      background-size: 143px 161px;
    }
  
    .img2 {
      background-size: 143px 165px;
    }
  
    #section-7 .green-banner, #section-4 .green-banner {
      width: 83%;
    }
  }
  
  @media screen and (min-width: 375px) and (max-width: 413px) {
    .efficacy.resectable-nsclc .section-1 h2.new-data {
      width: 371px;
      margin-left: -18px;
    }
  
    .resectable-nsclc .section-10 .bar-chart-horizontal {
      margin-left: 62px;
    }
  
    .resectable-nsclc.efficacy .percentage-bar-text {
      padding-left: 52px;
    }
  }
  
  @media screen and (min-width: 376px) {
    .efficacy.resectable-nsclc .section-10 .brain-section {
                /*margin: 50px auto 74px auto!important;*/
                 /*margin: 50px auto 64px auto!important;*/
      margin: 40px auto 54px auto!important;
    }
  }
  
  .efficacy.resectable-nsclc .section-12.bg-grey:before, .efficacy.resectable-nsclc .section-13.bg-grey:before, 
    .efficacy.resectable-nsclc .adaura-callout:before, 
    .efficacy.resectable-nsclc .section-7.bg-grey:before, .efficacy.resectable-nsclc .section-9.bg-grey:before {
    display: none;
    box-shadow: none;
  }
  
  .efficacy.resectable-nsclc .section-9 .double-footnotes {
    text-indent: -6px;
  }
  
  .section-7 .adaura-km-chart .col-md-6.col-sm-12.column-1 .sm-callout p {
    padding: 33px 18px 34px 18px;
  }
  
  .efficacy.resectable-nsclc .section-13 .nccn-content:before {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/leftcurve-white.png) no-repeat;
  }
  
  .efficacy.resectable-nsclc .section-15 .nccn-content:before {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/callout-landing.png) no-repeat;
      /*background-size: 100% 125px;*/
    background-size: 100% 94px;
  }
  
  .efficacy.resectable-nsclc .section-13 .nccn-content, .efficacy.resectable-nsclc .section-15 .nccn-content {
    background: #ffffff;
  }
  
  p.footnotes.hash-ft {
    text-indent: -4px !important;
  }
  
  .efficacy .data-flex-box p {
    margin: 0;
  }
  
  .efficacy .heading-block {
    text-align: center;
    margin-top: -25px;
    font-family: 'Barlow', sans-serif;
    margin: 0;
  }
  
  .efficacy #section-15 .nccn-copy.grey-bg {
    padding: 7px 35px 7px 15px!important;
  }
  
  .efficacy .heading-block .line-1 {
      /*    font: normal normal 21px/25px Barlow;*/
      /*font-weight: 500;*/
    font: normal normal 22px/25px Barlow;
    font-weight: 500;
  }
  
  .efficacy .heading-block .line-2 {
          /*font: normal normal 800 63px/55px Barlow;*/
    font: normal normal 800 65px/57px Barlow;
      /* margin: 0px; */
      /*margin: 0px;*/
    ;
  }
  
  .efficacy .heading-block .line-3 {
          /*font: normal normal  23px/55px Barlow;*/
      /* margin-left: 25px; */
      /* margin-left: 15px; */
      /*margin-left: 14px;*/
      /*font-weight: 500;*/
      /*color: #5B305D;*/
      /*margin-top: -5px;*/
    font: normal normal  23.5px/36px Barlow;
      /* margin-left: 25px; */
      /* margin-left: 15px; */
    margin-left: 14px;
    font-weight: 500;
    color: #5B305D;
      /*margin-top: -13px;*/
    ;
  }
  
  .efficacy .heading-block .line-3 {
    margin-left: 0;
  }
  
  .efficacy .yellow-box {
      /*    box-shadow: inset 0px 3px 6px #00000029, 0px 4px 6px #00000029;*/
      /*border: 2px solid #CEDB00;*/
      /*border-radius: 9px;*/
      /*font: normal normal 16px/18px Barlow;*/
      /*font-weight: 500;*/
      /*padding: 10px 5px;*/
      /*text-align: center;*/
      /*width: 93%;*/
      /*margin: 0 auto;*/
      /*height: 60px;*/
      /*color: #5B305D;*/
    box-shadow: inset 0px 3px 6px #00000029, 0px 4px 6px #00000029;
    border: 2px solid #CEDB00;
    border-radius: 9px;
    font: normal normal 16px/18px Barlow;
    font-weight: 500;
    padding: 8px 5px;
    text-align: center;
    width: 95.7%;
    margin: 0 auto;
    height: 57px;
    color: #5B305D;
    margin-left: 20px;
    margin-top: 10px;
  }
  
  .efficacy .yellow-box p {
    font: normal normal 16px/18px Barlow;
    font-weight: 500;
    max-width: 736px;
    color: #5B305D;
    margin: 0 auto;
  }
  
  .efficacy .yellow-box b {
    font-weight: 800;
  }
  
  .efficacy .astick {
    position: relative;
    top: -2px;
  }
  
  .efficacy .data-flex-box {
    display: flex;
      /*margin: 20px 9px 15px;*/
    margin: 20px 0px 15px 6px;
    justify-content: space-around;
  }
  
  .efficacy .data-flex-box .data-flex-box-col {
    width: calc(50% - 30px);
  }
  
  .efficacy .data-flex-box .above-card-wrap {
    text-align: center;
  }
  
  .efficacy .data-flex-box .green-text-line-1 {
      /*    font: normal normal 800 29px/17px Barlow;*/
      /*color: #0E8995;*/
    font: normal normal 800 29px/17px Barlow;
    color: #0E8995;
  }
  
  .efficacy .data-flex-box .green-text-line-2 {
      /*    font: normal normal 500 14px/17px Barlow;*/
      /*color: #0E8995;*/
      /*margin: 5px 0px;*/
    font: normal normal 500 14px/17px Barlow;
    color: #0E8995;
    margin: 8px 0px 3px 0px;
  }
  
  .efficacy .b-le {
      /*    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/new-box.png) no-repeat;*/
      /*width: 100%;*/
      /*height: 252px;*/
      /*background-size: 100% 100%;*/
      /*background-position: center;*/
      /*position: relative;*/
      /*margin-top: -4px;*/
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/new-box.png) no-repeat;
    width: 100%;
    height: 250px;
    background-size: 100% 100%;
    background-position: center;
    position: relative;
    margin-top: -4px;
  }
  
  .efficacy .text-3 {
    font-family: 'Barlow';
    font-size: 19px;
    font-weight: 900;
    color: #ffffff;
    line-height: 17px;
    padding-top: 23px;
    text-align: center;
  }
  
  .efficacy .row-1 {
    display: flex;
    padding-top: 40px;
    justify-content: center;
  }
  
  .efficacy .row-1 .col-1 {
    width: 97%;
  }
  
  .efficacy .row-1 .col-1 .text-4 {
    color: #5B305D;
    font-size: 28px;
    text-align: center;
    display: flex;
    justify-content: center;
  }
  
  .efficacy .text-5 {
      /*    color: #5B305D;*/
      /*padding-top: 21px;*/
      /*margin-bottom: -4px;*/
      /*font: normal normal 500 14px/16px Barlow;*/
      /*letter-spacing: -0.5px;*/
      /*line-height: 16px!important;*/
      /*text-align: center;*/
      /* font-size: 14px; */
      /* margin-top: 2px; */
      /*padding-bottom: 4px;*/
    color: #5B305D;
    padding-top: 21px;
    margin-bottom: -4px;
    font: normal normal 13px/16px Barlow;
      /* letter-spacing: -0.5px; */
    line-height: 16px!important;
    text-align: center;
      /* font-size: 14px; */
      /* margin-top: 2px; */
    padding-bottom: 4px;
  }
  
  .efficacy .font-b {
    font-weight: bold;
  }
  
  .efficacy .text-6 {
      /*    font-family: 'Barlow';*/
      /*font-size: 85%;*/
      /*color: #4F2C5D;*/
      /*text-align: center;*/
      /*font: normal normal 500 14px/16px Barlow;*/
      /*line-height: 16px!important;*/
    font-family: 'Barlow';
    font-size: 85%;
    color: #4F2C5D;
    text-align: center;
    font: normal normal 13px/16px Barlow;
    line-height: 16px!important;
  }
  
  .efficacy .b-le .row-2 {
          /*padding-top: 11px;*/
    padding-top: 10px;
  }
  
  .efficacy .text-11 {
      /*    text-align: center;*/
      /*font: normal normal normal 14px/17px Barlow;*/
      /* margin: 5px 0; */
      /* letter-spacing: -0.16px; */
      /*color: #5B305D;*/
      /*font: normal normal 500 14px/17px Barlow;*/
      /*line-height: 17px!important;*/
      /*margin: 0px 0px 10px 0px;*/
    text-align: center;
    font: normal normal normal 13px/16px Barlow;
      /* margin: 5px 0; */
      /* letter-spacing: -0.16px; */
    color: #5B305D;
    font: normal normal 13px/16px Barlow;
    line-height: 17px!important;
    margin: 0px 0px 10px 0px;
  }
  
  .efficacy .barlow-ex-bold {
    font-weight: 800;
  }
  
  .efficacy .b-le .row-3 {
          /* max-width: 358px; */
      /* margin-left: 18px; */
      /* margin-right: 10px; */
      /*max-width: 349px;*/
      /*margin: 0 auto;*/
          /* max-width: 358px; */
      /* margin-left: 18px; */
      /* margin-right: 10px; */
    max-width: 349px;
    margin: 0 auto;
    margin-top: 10px;
  }
  
  .efficacy .b-le .row-3 .footnote, .efficacy .b-le .row-4 .footnote {
          /* font: normal normal normal 12px/16px Barlow; */
    font: normal normal normal 13px/15px Barlow!important;
    color: #606060;
    text-align: center;
    letter-spacing: -0.15px;
  }
  
  .efficacy .footnote span.en-prd {
    margin-left: -5px;
  }
  
  .efficacy .data-flex-box .data-flex-box-col {
          /*width: calc(50% - 30px);*/
    width: calc(50% - 16px);
  }
  
  .efficacy .b-re {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/landing-popup/new-box.png) no-repeat;
    width: 100%;
    height: 251px;
    background-size: 100% 100%;
    background-position: center;
    position: relative;
    text-align: center;
    z-index: 9;
  }
  
  .efficacy .data-flex-box .data-flex-box-col:nth-child(2) .above-card-wrap {
    margin-top: -13px;
  }
  
  .efficacy .pink-text {
    font-weight: normal!important;
  }
  
  .efficacy .d-fl {
    display: flex;
    justify-content: center;
    margin-bottom: -3px;
  }
  
  .efficacy .d-fl img {
          /* z-index: 99; */
      /* height: 55px; */
      /* position: relative; */
      /* top: 23px; */
      /* right: 56px; */
    z-index: 99;
    height: 54px;
    position: relative;
    top: 28px;
    right: 57px;
  }
  
  .efficacy .d-fl p {
    font-family: 'Barlow';
    font-size: 14px;
    line-height: 17px;
    font-weight: 500;
    margin-top: 11px;
    position: relative;
    left: 5px;
  }
  
  .efficacy .data-flex-box .data-flex-box-col:nth-child(2) .above-card-wrap .barlow-bold {
      /*    position: relative;*/
      /* left: -44px; */
      /*left: -60px;*/
      /*top: 1px;*/
    position: relative;
        /* left: -44px; */
    left: -55px;
    top: 1px;
  }
  
  .efficacy .above-card-wrap .d-fl p span:nth-child(1) {
    margin-bottom: 6px;
  }
  
  .efficacy .above-card-wrap .font-style {
    display: block;
    font-weight: 500;
    line-height: 17px;
    font-size: 14px;
    margin-top: 1px;
        /* margin-left: -79px; */
    position: relative;
    left: -52px;
    margin-bottom: 1px;
  }
  
  .efficacy .row-1 .col-1 .text-4 span {
    font-size: 52px;
    font-weight: 800;
  }
  
  .efficacy .text-3-1 {
    font-family: 'Barlow';
    font-size: 19px;
    font-weight: 900;
    color: #ffffff;
    line-height: 17px;
    padding-top: 23px;
    text-align: center;
    text-transform: uppercase;
  }
  
  .efficacy .text-4-1 {
    font: normal normal 800 52px/62px Barlow;
    letter-spacing: -0.52px;
    color: #5B305D;
    margin: 0;
    padding-top: 38px;
    padding-bottom: 17px;
  }
  
  .efficacy .text-5-1 {
    font: normal normal 800 28px/20px Barlow;
    letter-spacing: 0px;
    color: #5B305D;
    margin: 6px 0px;
    margin-top: 6px!important;
  }
  
  .efficacy .text-6-1 {
    font: normal normal 500 16px/20px Barlow;
    color: #5B305D;
    margin-bottom: 3px;
    margin-top: -2px;
    margin-top: 2px!important;
  }
  
  .efficacy .text-7-1 {
    text-align: center;
    font: normal normal normal 13px/16px Barlow;
      /* letter-spacing: -0.16px; */
    color: #5B305D;
    margin-bottom: 7px;
    line-height: 17px!important;
    margin-top: 8px!important;
  }
  
  .efficacy .b-re .row-4 {
    margin-top: 8px;
  }
  
  .efficacy .b-re .row-4 .footnote {
    max-width: 310px;
    margin: 0 auto;
    text-align: center;
    font: normal normal normal 13px/15px Barlow!important;
    color: #606060;
      /* margin-left: 15px; */
    ;
  }
  
  .efficacy .footnote span.en-prd {
    margin-left: -5px;
  }
  
  .efficacy .d-fl p span {
    font-size: 29px;
    font-weight: 800;
    color: #0E8995;
    margin-left: 0;
  }
  
  .efficacy .border-gr {
    border-top: 1px solid white;
    max-width: 516px;
    margin: 0 auto;
    height: 10px;
      /* display: flex; */
      /* justify-content: center; */
      /* align-items: center; */
      /* margin-left: 78px; */
      /* margin-right: 41px; */
    ;
  }
  
  .efficacy .data-copy-txt {
          /*margin-bottom: 25px;*/
              /* margin-bottom: 25px; */
    margin-top: 24px;
    margin-left: -12px;
  }
  
  .efficacy ul.median-list {
    padding-left: 18px;
    margin-top: -19px !important;
  }
  
  .efficacy ul.median-list-1 {
    padding-left: 18px;
    margin-top: 21px;
  }
  
  .efficacy .data-copy-txt p {
      /*    font-family: 'Barlow';*/
      /*font-size: 22px;*/
      /*line-height: 26px!important;*/
      /*letter-spacing: -0.4px;*/
      /*color: #008995;*/
      /*font-weight: 600;*/
      /*text-align: center;*/
    font-family: 'Barlow';
    font-size: 22px;
    line-height: 26px!important;
    letter-spacing: -0.04px;
    color: #008995;
    font-weight: 600;
    text-align: center;
      /* margin-top: 15px; */
    ;
  }
  
  .efficacy .b-bold {
    font-weight: 900;
  }
  
  .efficacy ul.median-list-1 li {
    margin-bottom: 14px;
    max-width: 742px;
  }
  
  .efficacy #accordion-sec-n-1 .panel-body {
    padding-bottom: 0!important;
    padding-left: 0!important;
    padding-right: 0!important;
  }
  
  .efficacy #accordion-sec-n-1 .newImage {
          /*padding: 30px 15px 15px 15px;*/
    padding: 10px 15px 15px 15px;
  }
  
  .efficacy .graph-data {
    background: #5B305D;
    height: 94px;
    border-radius: 0 0 15px 15px;
  }
  
  .efficacy .graph-top-info p {
    height: 30px;
    display: flex;
    justify-content: center;
    align-items: center;
    padding-top: 14px;
    margin-bottom: 16px;
  }
  
  .efficacy .graph-top-info sup, .efficacy .graph-btm-info sup {
    font-weight: normal;
    top: -0.7em;
    font-size: 50%;
  }
  
  .efficacy .median-list,  .efficacy .median-list li:last-child {
    margin-bottom: 0;
    padding-bottom: 0;
  }
  
  .efficacy .brd-btm hr {
    width: 553px;
      /* color: #a3a3a3; */
    background-color: #a3a3a3;
      /* margin-top: 40px; */
    margin: 40px auto 0px;
    margin-bottom: 14px;
      /* margin-bottom: 40px; */
    border-top: 1px solid #999999;
  }
  
  .efficacy ul.median-list-5 {
    margin-bottom: 100px;
    padding-inline-start: 20px;
  }
  
  .efficacy.resectable-nsclc ul.median-list-5.list-user {
    margin-bottom: 38px;
  }
  
  .efficacy.resectable-nsclc .bg-grey.section-6.sec-userr:after {
    box-shadow: none;
  }
  
  .efficacy ul.median-list-5 li {
    margin-bottom: 16px;
  }
  
  .efficacy ul.median-list-5 li:last-child {
    margin-bottom: 0px;
  }
  
  .efficacy ul.median-list li::marker, .efficacy ul.median-list-1 li::marker, .efficacy ul.median-list-5 li::marker, .efficacy ul.ffb-sb li::marker {
    color: #009398!important;
  }
  
  .efficacy .graph-btm-info p {
          /* height: 30px; */
    display: flex;
    justify-content: center;
    align-items: center;
    padding-top: 2px;
  }
  
  .efficacy .graph-top-info p, .efficacy .graph-btm-info p {
    font-size: 16px;
    line-height: 17px;
    font-family: 'Barlow';
    color: #fff;
    text-align: center;
  }
  
  .efficacy .graph-top-info p span:nth-child(2), .efficacy .graph-btm-info p span:nth-child(2) {
    font-weight: 700;
  }
  
  .efficacy .ex-txt {
    font-size: 40px;
    font-weight: bold;
    line-height: 17px;
    letter-spacing: -0.36px;
  }
  
  .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content .d-none {
    display: none;
  }
  
  .efficacy.resectable-nsclc.resect-efficacy .sm-callout  ul.ffb-sb {
    margin-left: 10px;
  }
  
  @media screen and (min-width: 645px) and (max-width: 991px) {
    .efficacy.resectable-nsclc .section-1 .newsection-content .dfs-content-box .abs-top {
      top: -18px;
    }
  
    .efficacy.resectable-nsclc .section-1 .section-content-2.newsection-content ul {
      margin-top: -7px;
    }
  }
  
  @media screen and (min-width: 500px) and (max-width: 767px) {
    .metastatic-nsclc .brain-img-section {
      max-width: 460px;
      margin: 0 auto;
      left: 0;
    }
  
    .metastatic-nsclc .section-6 .graphic-subhead {
      padding-left: 35px;
      margin: 0;
    }
  }
  
  .btm-shadow:after {
    bottom: -4px;
  }
  
  @media only screen and (device-width : 360px) and (device-height : 740px) and (orientation :portrait) {
   
    .metastatic-nsclc .section-6 .hor-line {
      max-width: 260px;
      left: 16px;
    }
  
    .metastatic-nsclc .section-6 ul.hor-scale {
      max-width: 326px;
      left: 5px;
    }
  
    .metastatic-nsclc .section-6 .hor-ruler {
      width: 63px;
    }
  }
  
  @media screen and (min-width: 350px) and (max-width: 374px) {
    .metastatic-nsclc .section-6 .bar-chart-horizontal {
      width: 333px;
    }
  
    .metastatic-nsclc .section-6 .hor-line {
      max-width: none;
      left: -13px;
      width: 255px;
    }
  }
  
  @media screen and (min-width: 358px) and (max-width: 374px) {
    .metastatic-nsclc .section-6 .hor-line {
      max-width: none;
      left: 46px;
      width: 333px;
    }
  }
  
  .cnd-dfs-chart-wrapper {
    margin-bottom: 20px;
  }
  
  .efficacy.resectable-nsclc ul.median-list5-one {
    margin-bottom: 55px!important;
  }
  
  p.footnotes.nccn-footnotes.o-align {
    text-indent: -4px;
  }
  
  body.fixed-top-margin.efficacy.metastatic-nsclc.metastatic-efficacy.meta-chemotherapy.meta-chemo-efficacy.default-fonts.dom-ready .accordion-container .collapse-panel-heading .fa {
    right: 7px;
  }
  
  @media screen and (max-width: 991px) {
    .callout-box > p:last-child{
      /*margin-bottom: 29px;*/
    }
    .progression-free-accordion .pbl{
      padding-right: 38px !important;
    }
  .first-line .new_final_ilu{
    width: 240px;
    height: 120px;
    left: -25px;
    top: 154px;
    z-index: 999;
    background:url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/mobile/new_final_os_mobb.png)no-repeat;
    background-size: cover;
  }
  .is-visible .slide-frm-left, .is-visible .slide-frm-right {
        transition:none;
    }
    ul.bullet-list.pbl {
      padding-top: 16px;
  }
    .new_final_ilu{
      left: -45px !important;
      top: -84px !important;
    }
    .no-margin-btm {
      margin-bottom: 0 !important;
    }
  
    .efficacy.metastatic-nsclc #pfs .pfs-hr {
      margin-bottom: 7px;
    }
  
    .metastatic-efficacy ul.bullet-list.keep-center {
      width: 94%;
      margin-right: 10px;
      padding-left: 10px;
      padding-right: 10px;
    }
  
    .metastatic-efficacy ul.bullet-list.keep-center li::before {
          left: -2px;
          top: -2px;
    }
    
      .metastatic-efficacy ul.bullet-list.no-margin-btm li::before {left: -2px;}
  
    .meta-chemo-efficacy.metastatic-nsclc .section-2 .bar-chart-horizontal .hor-bar-one {
      overflow: hidden !important;
    }
  
    .section-9 p.footnotes.mobile-only {
      margin-left: 0;
    }
        
        /*#cns-data ul.bullet-list li:last-child {
          letter-spacing: -0.01em;
      }*/
        
    #subgroups .footnotes.last-child {
      padding-right: 10px;
    }
  
    .cnd-dfs-chart-wrapper {
      margin-bottom: 65px;
    }
  
    p#eff-mobile-chart-brain-title {
      text-align: left;
    }
  
    .mob-p-0 > .page-section-inner.container {
      padding: 0;
    }
  
    p#eff-margin-rethink-a {
      margin-top: 18px;
    }
  
    .section-4.mob-p-0 .adj-table th:first-child {
      width: 135px!important;
    }
  
    .section-4.mob-p-0 .adj-table th {
      width: 105px!important;
    }
  
    .efficacy.resectable-nsclc .section-10 .brain-section {
      margin-top: 68px!important;
      margin-bottom: 54px!important;
    }
  
    .progression-survival-graph img {
      margin-top: -26px;
      margin-bottom: -1px;
    }
  
    .cns-progression-graph img {
      margin-left: -10px;
    }
  
    .efficacy.resectable-nsclc .green-banner {
      width: 87%;
    }
  
    .efficacy.resectable-nsclc .section-5 .green-banner {
      width: 82%!important;
    }
  
    .efficacy.resectable-nsclc .section-12 .green-banner {
      width: 85%;
    }
  
    .efficacy.resectable-nsclc .adaura-callout .green-banner {
      width: 92.5%;
    }
  
    .efficacy.resectable-nsclc .section-5 .green-banner p.callout {
      width: 300px;
    }
  
    .efficacy.resectable-nsclc .section-5 .green-banner.m-top-zero.user-s-1 {
      width: 86%!important;
    }
  
    .efficacy.resectable-nsclc .section-13  #margin-eff-dfs-a {
      margin-top: 30px;
    }
  
    .meta-chemo-efficacy .flaura2-demo-tableMob {
      padding: 5px;
    }
  
    .clinicopathologic-tbl th.chart-head3.text-left.ffb-b.table-flaura2-pink-header {
      padding: 0px  5px  !important;
    }
  
    .meta-chemo-efficacy .flaura2-demo-tableMob th.chart-head3.text-left.ffb-b.table-flaura2-pink-charac-header {
      padding: 4px 0 13px 8px;
    }
  
    .meta-chemo-efficacy .flaura2-demo-tableMob .table-flaura2-pink-header {
      padding: 5px;
    }
  
    .meta-chemo-efficacy .flaura2-demo-tableMob .span1 th {
      font-size: 15px;
    }
  
    .meta-chemo-efficacy .flaura2-demo-tableMob .chart-body {
      font-size: 15px;
    }
  
    .meta-chemo-efficacy .flaura2-demo-tableMob th.chart-head3.text-left.ffb-b.table-flaura2-pink-charac-header {
     /*padding:  4px 0 13px 8px;*/
     /*top: 0;*/
      padding: 4px 0 0px 8px;
      top: 13px;
    }
  
    .metastatic-efficacy .flaura-accordian.clinicopathologic-tbl .panel-body {
      padding: 12px 0 10px 0 !important;
    }
  
    .metastatic-nsclc .section-9 .customTable.flaura2-demo-tableMob td {
      padding: 10px 0px 10px 5px !important;
    }
  
    .meta-chemo-efficacy.metastatic-nsclc .flaura2-demo-tableMob td.table-flaura2-ident {
      text-indent: 1rem !important;
      text-indent: 0rem !important;
    }
  }
  
  @media screen and (max-width: 767px) {
    .efficacy .heading-block .line-3 {
      max-width: 318px;
      margin: 0 auto !important;
    }
  }
  
  @media screen and (min-width: 992px) {
    .os-block-fix{
    position: relative;
    right: 5px;
  }
      .cropd-chart{
        overflow:hidden;
        height: 313px;
      }
       .median-chart .cropd-chart{
        overflow:hidden;
        height: 331px;
      }
    .meta-chemotherapy .os-rate-box.box-center.txt-ctr ul.bullet-list{
        max-width: 81% !important;
    }
    .median-chart .footnotes{
      max-width: 604px;
      margin: 0 auto !important;
      font-size: 16px;
      line-height: 20px !important;
    }
      .median-chart .footnotes:last-child{
          max-width: 609px;
          padding-left: 19px;
          padding-right: 0px;
          left: 2px;
          margin: 8px auto 14px !important;
          text-align: left;
    }
    .cropd-chart >img{
          scale: 1.14;
    }
    .meta-chemo-efficacy.metastatic-nsclc p.chemo-eff-after-cns-table.footnotes {
      padding-right: 50px;
    }
  
    .meta-chemo-efficacy .cns-response-table th:last-child {
      padding-left: 38px;
    }
  
    p.footnotes.chemo-eff-after-cns-table {
      padding-right: 29px;
    }
  
    #flaura-study-design, #flaura2 {
      padding-top: 45px;
      margin-top: 0;
    }
  }
  
  .mob-only{
    display:none;
  }
  
  @media only screen and (max-width: 991px){
    .efficacy  .cns-purple-box .text-box{
      transform:skew(10deg);
    }
     .efficacy  .cns-purple-box .text-box p{
         font-size: 14px;
    }
    .efficacy .cns-purple-box .text-box p:last-child{
      font-size: 12px;
    }
   .efficacy .cns-purple-box .number-box {
      transform:skew(10deg);
      font-size: 62px;
      width: unset;
      height: 100%;
      position: static;
      padding: 0px 6px;
    }
     .efficacy .cns-purple-box{
      left: unset;
      background: #5B305D;
      height: unset;
      transform: skew(-10deg);
      border-radius: 18px;
      align-items: center;
      padding: 10px;
    }
    .pbl{
      padding-bottom: 30px !important;
    }
    .hoc-accord .panel-body .text.parbase.section:first-of-type > div > table > tbody > tr.span1.table-flaura2-bg-gray > td.chart-body.ffb-med{
      padding-right:0 !important;
    }
    .hoc-accord .panel-body .text.parbase.section:first-of-type > div > table > tbody > tr:nth-child(1) > td:nth-child(2){
      /* padding: 0px !important; */
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-2 h2.unpre-median{
      padding-bottom:55px;
    }
    #additional-results > div.page-section-inner.container > div:nth-child(1) > div > h2{
      padding-bottom: 15px;
    }
    .hoc-accord .panel-body .text.parbase.section:first-of-type > div > table > tbody > tr:nth-child(2) > td:nth-child(3){
      /* padding: 0 !important; */
    }
    .hoc-accord .panel-body .text.parbase.section:first-of-type > div > table > tbody > tr:nth-child(3) > td:nth-child(3){
      padding: 0 7px !important;
    }
  
      .hoc-accord .panel-body .text.parbase.section:first-of-type > div{
      padding: 0 12px !important;
    }
    .meta-chemo-efficacy .flaura2-demo-table .table-flaura2-pink-header{
      padding: 0 2px!important;
      line-height: 14px !important;
    }
    .flaura2-demo-table.posthoc-table th{
      font-size: 12px;
    }
    .meta-chemo-efficacy .posthoc-table th.chart-head3.text-left.ffb-b.table-flaura2-pink-charac-header{
      font-size: 13px;
      line-height: 14px !important;
      padding: 0 0 10px 0 !important;
    }
    table.customTable.tab-title.median-tab.flaura2-demo-table.posthoc-table th {
      padding-bottom: 5px !important;
  }
    .meta-chemo-efficacy table.flaura2-demo-table td{
      font-size: 14px;
    }
  table.posthoc-table > tbody > tr:nth-child(5) > td:nth-child(2){
      padding-right: 0 !important;
    }
  }
    .hoc-accord .panel-body .text.parbase.section:first-of-type > div{
      padding: 0 14px;
    }
  .meta-chemo-efficacy.metastatic-nsclc .flaura2-demo-table .table-flaura2-special-grey td{ 
    background-color:#F1F1F1!important;
  }
  .teal-subhead{
      font-size: 22px;
      line-height: 26px !important;
      font-weight: 500;
      margin: 30px 0px;
      color: #008995;
  }
  .teal-txt{
        color: #008995 !important;
  }
  
  .text-center{
    text-align:center;
  }
  p.bullet.interim-footnote{
    margin: 0 10px 10px 24px;
    position: relative;
  }
  p.bullet.interim-footnote:before{
      content: '\2022';
      color: #009398;
      position: absolute;
      left: 9px;
      /* left: -9px; */
      /*top: -1px;*/
      font-size: 16px;
  }
  .metastatic-nsclc.meta-chemo-efficacy .section-1 .copy-per.chevron-down{
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/84%20shape.png) center center / contain no-repeat;
  }
  
  .cns-purple-box{
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/76-purple-shape.svg);
    background-repeat: no-repeat;
    background-size: 100%;
    max-width: 770px;
    line-height: 21px !important;
    padding: 6px 0 0 48px;
    display: flex;
    height: 96px;
    left: 24px;
    position: relative;
  }
  
  .cns-purple-box .number-box{
    color: white;
    font-size: 62px;
    line-height: 19px;
    width: 18%;
    padding: 30px 5px 0 10px;
    height: 55px;
    position: relative;
    right: 10px;
    font-weight: 700;
  }
  .cns-purple-box .text-box p {
    color:white;
      font-size: 18px;
      font-weight:700;
      line-height: 21px;
      margin-bottom:0;
  }
  .cns-purple-box .text-box p:last-child{
    font-size:16px;
    font-weight:400;
  }
  .cns-purple-box .text-box p:last-child span{
    font-weight:700
  }
  
  .pb-30{
    padding-bottom:30px !important;
  }
  
  .metastatic-efficacy ul.bullet-list.chemo-eff-after-vertical-graph.pb-30 li {
      padding-bottom: 15px;
  }
  
  .surviva-txt .medium{
      font-weight: 600 !important;
      font-size: 24px;
  }
  .meta-chemo-efficacy .reduced-risk-ba  .extrabold.copy-content-lg.surviva-txt{
    font-size:26px;
  }
  .new-footnotes-section{
    margin-bottom:80px;
  }
  
  .meta-chemo-efficacy .median-overall  .extrabold.copy-content-lg.surviva-txt{
    font-size:36px;
    line-height: 9px;
  }
  
  .normal-weight{
    font-weight:400
  }
  .first-line-nccn .polygon{
    height: 104px;
  }
  
  .first-line-nccn .nccn-content:before{
    height: 104px !important;
  }
  
  .first-line-nccn .content{
      margin: 11px 0;
  }
  
  .first-line-nccn{
   margin-bottom: 30px !important;
   width: unset !important;
   max-width: 750px !important;
  }
  
  .first-line-nccn .nccn-content{
    max-width: 550px;
  }
  .new_final_ilu{
    display:block;
    position:absolute;
    width: 245px;
    height: 105px;
    left: -104px;
    top: -67px;
    z-index: 999;
    background:url(/content/dam/open-digital/tagrisso-hcp/us/en/chemotherapy/desktop/new_final_os_desk.png)no-repeat;
    background-size: cover;
  }
  b.b600{
    font-weight:600 !important;
  }
  @media screen and (max-width : 991px){
.box-center.os-rate-box.txt-ctr .callout-box > p:last-child{
    margin-bottom : 30px
}
}
  
  /********8 18-11-2024 ********/
  @media screen and (min-width : 790px) and (max-width : 991px){
      .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph {
        max-width: 350px;
        margin-bottom: 50px;
        left: 28px;
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .hor-txt2{
       right : 3px
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .hor-txt1{
        max-width : 150px;
        left :-10px;
        bottom:-30px;
        line-height:20px !important
    }
    .metastatic-nsclc.metastatic-efficacy .section-6 p.vertical-txt{
        right:50px
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt{
        top:-80px
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .bar-graph1-copy{
        left :130px;
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar.small-bar{
        height: 50px;
    } 
    .bar-graph1-copy .top-content{
        margin-top :30px;
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .bottom-content.btm-content-2{
        margin-top : 200px !important 
    }
    .hor-txt.hor-txt2.text-center {
       left : 130px 
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt:nth-of-type(2){
        top: -120px
    }
  }
  
@media screen and (min-width : 320px) and (max-width : 991px){
    .callout-box > p:last-child{
       margin-bottom :30px
    }
    
     .new_final_ilu{
     top:-45px !important;
     left:10px !important
 } 
}
 @media screen and (max-width : 810px){
           .section-heading-mobile:after{
                    right : 10px
            }
}

 @media screen and (max-width : 390px){
    .acc-title.extrabold.mx-w-310 {
        max-width : 310px;
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt
    {
        top : -100px
    }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .cns-progression-vertical-graph .bar .top-txt:nth-of-type(2){
        top : -120px
    }
     .btm-list{
    margin-top : 20px !important;
}
    .callout-box > p:last-child{
        margin-bottom : 0px
    }
}
 @media screen and (max-width : 370px){
    .metastatic-nsclc .section-1 .vs-txt{
                margin-top : 2px
        }
    .meta-chemo-efficacy.metastatic-nsclc .section-6 .bar-graph2-copy{
   left : 88px
    }
    .nowrap{
    white-space : normal
    }
    .meta-chemo-efficacy .visit-btn{
        width : 280px
    }
    .component-section .bg-white{
        overflow : hidden
    }
}


 @media screen and (min-width : 392px){
   .dor-orr-block .btm-list{
     max-width: 460px;
   }
 }
 
 
 
 
 

/*Fixing nav bar issue */

@media screen and (max-width : 1200px){
     .top-header .navbar-header .logo img {
    max-width : 200px
    }
   .vertical-list-dropdown .list-dropdown.dropdown-menu li{
     max-width : 300px
    }
 .top-header-links .top-nav ul{
  max-width : 480px;
  position :absolute;
  right : 5px;
  top: -3px
 }
 .therapyToggleWrap{
  max-width : 350px
 }
}
@media screen and (max-width : 1160px){
     .top-header .navbar-header .logo img {
    max-width : 180px
    }
  .vertical-list-dropdown .list-dropdown.dropdown-menu li{
     max-width : 300px
    }
 
 .top-header-links .top-nav ul{
  max-width : 480px;
  position :absolute;
  right : 5px;
  top: -3px
 }
 .therapyToggleWrap{
  max-width : 250px;
 }
}

@media screen and (max-width : 1110px){
  .top-header .navbar-header .logo img {
    max-width : 170px
    }
  .vertical-list-dropdown .list-dropdown.dropdown-menu li{
     max-width : 230px
    }
  .therapyToggleWrap{
  max-width : 235px;
   box-sizing : border-box; 
   padding : 6px 4px
 }
}


@media screen and (max-width : 1120px){
.top-header-links .top-nav ul { 
 max-width : 460px
}
}

@media screen and (max-width : 1080px){
.top-header-links .top-nav ul { 
 max-width : 350px
}
}
@media screen and (max-width : 765px){
    .dose-red-sub-list{
        max-width : 680px
    }
}

.new_final_ilu{
    background-image:url("/content/dam/open-digital/tagrisso-hcp/us/en/desktop/flaura2/final-os-removebg-preview.png");
    background-size:80%;
    left:-40px;
    top:-40px
}