/*about page styling*/
.headline {
  margin: 34px 0 0 0;
}

.pill-sec {
  display: inline-flex;
  margin: 40px auto 35px;
}

.pill-img {
  margin-right: 13px;
}

.nccn-sec {
  display: inline-flex;
}

.nccn-content {
  margin: 80px auto 35px;
  max-width: 549px;
  padding: 0;
}

.subhead.subhead2 {
}

.subhead2 .pink-var:before {
  letter-spacing: 0;
}

.subhead2 .pink-var:after {
  right: 1px;
}

.acc-act {
  margin: 20px auto 75px;
  position: relative;
  margin-top: 44px;
}

.year-head, .year-desc {
  display: flex;
  justify-content: space-between;
  margin-left: 140px;
}

.year-head span, .year-desc span {
  display: block;
}

.year-desc {
  max-width: 590px;
  padding-left: 20px !important;
  width: 100%;
}

.year-head {
  font-size: 16px;
  line-height: 18px;
  max-width: 440px;
  margin: 0 auto;
}

.yr-1-head {
  margin-left: -23px;
}

.yr-2-head {
  margin-left: 0px;
}

.yr-3-head {
  left: 45px;
  position: relative;
}

.percent-line {
  height: 38px;
  display: flex;
  align-items: flex-end;
}

.year-desc .yr-desc-wrap > div {
  max-width: 290px;
  box-shadow: 0px 3px 6px #00000052;
  border-radius: 0px 0px 12px 12px;
  padding: 25px 15px 10px 15px;
  transition: ease-out;
}

.yr-desc-wrap {
  position: relative;
}

.yr-1-desc, .yr-2-desc {
  margin-right: 28px;
}

.year-head .extrabold {
  font-size: 32px;
  line-height: 29px;
}

.year-head .bold {
  font-size: 18px;
}

.year-desc .extrabold {
  font-size: 16px;
  line-height: 18px;
}

.year-desc .extrabold.pcent {
  font-size: 42px;
  line-height: 20px;
  margin-bottom: 12px;
  margin-right: 5px;
  top: 2px;
  position: relative;
}

.yr-2-desc .extrabold.pcent {
  float: left;
}

.year-desc .percent-line .extrabold sup {
  top: -0.6em;
  font-size: 55%;
}

.extrabold.pcent-right {
  font-size: 17px;
  line-height: 19px;
  top: -4px;
  position: relative;
  left: 3px;
}

span.extrabold.align-right {
  margin-top: -6px;
}

.year-desc .ffb-med {
  font-size: 12px;
  line-height: 16px;
}

.year-desc .ffb-med.vs-txt {
  font-size: 14px;
  line-height: 18px;
  padding-top: 4px;
  padding-bottom: 4px;
}

.subhead3 {
  margin-bottom: 5px;
}

p.map-animate {
  position: relative;
}

p.map-animate img {
  max-width: 416px;
  width: 100%;
  display: none;
  transition: 0.3s all ease-out;
  transition-delay: 10s;
}

.numbertick img {
  display: none;
  transition: 0.3s all ease-out;
  transition-delay: 10s;
}

.is-visible.map-animate img,.is-visible.numbertick img {
  display: block;
  margin: 0 auto;
}

span.vr-line-map {
  height: 0px;
  width: 2px;
  background: grey;
  position: absolute;
  left: 32.5%;
    /*top: 72%;*/
  top: 84%;
  transition: 1s ease;
  transition-delay: 1s;
}

span.vr-line-map:after {
  content: "";
  width: 0px;
  height: 2px;
  background: grey;
  position: absolute;
  left: 0;
  bottom: 0;
  transition: 1s ease;
  transition-delay: 2s;
}

.last-footnote {
  margin-bottom: 35px;
  text-indent: -9px;
}

.is-visible .vr-line-map {
  height: 146px;
}
/*.is-visible .vr-line-map:after { width: 445px;}*/

/*
Issue -3
.nccn-content .footnotes, .nccn-content.double-footnotes {
	text-indent: 0px;
}
*/
p.footnotes.double-footnotes.footnote-osimertinib {
    /*text-indent: -6px;*/
    /*text-indent: 0px;*/
  text-indent: -7px;
  padding-left: 5px;
}

p.footnotes.double-footnotes.footnote-osimertinib.footnote-ipad-text-two {
    /*text-indent: -9px;*/
    /*text-indent: 0px;*/
  ;
}

.footnotes.footnote-ipad-text {
  text-indent: -7px;
  text-indent: -5px;
}

/* new ingofraphic about */

.grid-container {
  display: grid;
  grid-template-columns: repeat(5, 1fr);
  gap: 10px;
  padding: 0;
  position: relative;
  margin: 0 auto;
}

.grid-item {
  padding: 0;
  text-align: center;
}

.related-item {
  /*margin-top: 10px;*/
      margin-top: -14px;
}

.top-percent-container {
  display: flex;
}

.grid-container > :nth-child(-n+5) {
  align-self: end;
  margin-bottom: 70px;
}
/* Line styling */
.line {
    position: absolute;
    top: 49%;
    left: 0px;
    width: 100%;
    height: 1px;
    background-color: #5B305D;
    z-index: 1;
}

/*@-webkit-keyframes expand{*/
/*    0%{width:0px}*/
/*    100%{width:100px}*/
/*}*/

.line.vertical {
    /*top: 31px;*/
  top: -24px;
  bottom: 0;
  right: 0;
  width: 439px !important;
  height: 2px;
  left: -39px;
    /*transform: rotate(90deg) translate(430px, -458px);*/
  transform: rotate(90deg) translate(430px, -650px);
  transform-origin: top;
  animation: drawVertical 2s forwards;
    /* background-color: #5B305D; */
  background: #707070;
  animation-delay: 5s;
    /*-webkit-animation: expand 5s;*/
  ;
}

.line.mapline.desktop-only {
  transform: translate(715px, 425px);
  width: 0%;
  height: 2px;
  bottom: 0;
  right: 0;
  top: 200px;
    /*background-color: #5B305D;*/
  background: #707070;
  transform-origin: right;
  animation: drawRightToLeft 2s forwards;
  animation-delay: 5s;
}

@keyframes drawVertical {
  from {
    width: 0;
    transform: rotate(90deg) translate(186px, -830px);
  }

  to {
    width: 44%;
  }
}

@keyframes drawRightToLeft {
  from {
    width: 0;
    transform: translate(715px, 425px);
  }

  to {
    width: 12%;
    transform: translate(731px, 425px);
  }
}

/* Circle styling */
.circle {
    position: absolute;
    top: 39%;
    height: 9px;
    transform: translateY(100%);
    z-index: 2;
}
/* Position circles  */
.circle-1 {
  left: 0%;
}

.circle-2 {
  left: 20%;
}

.circle-3 {
  left: 40%;
}

.circle-4 {
  left: 60%;
}

.circle-5 {
  left: 80%;
}

.circle-6 {
  left: 98%;
  /*top: 37.9%;*/
  top: 39.5%;
}

/* Text styling */
span.year-txt {
  font-size: 34px;
  font-weight: 700;
  text-align: left;
  display: block;
  color: #5B305D;
  line-height: 29px;
  margin-bottom: 4px;
}

span.year-desc-txt {
  line-height: 18px;
  font-size: 18px;
  text-align: left;
  display: block;
  color: #5B305D;
}

span.percent-txt {
  font-family: 'Barlow';
  font-size: 41px;
  font-weight: 800;
  line-height: 32px;
  color: #5B305D;
  text-align: left;
  display: block;
  margin: 0px 3px 0 0;
}

span.percent-symbol {
  font-size: 21px;
  color: #5B305D;
  font-weight: 700;
  display: inline;
  text-align: left;
  vertical-align: bottom;
  position: relative;
  bottom: 7px;
}

span.percent-desc-txt {
  font-size: 17px;
  line-height: 18px;
  font-weight: 800;
  color: #5B305D;
  text-align: left;
  display: block;
  line-height: 1;
}

span.full-note-text {
  font-size: 12px;
  line-height: 16px;
  font-weight: 400;
  text-align: left;
  display: block;
  color: #5B305D;
}

span.full-desc-text {
  font-size: 16px;
  text-align: left;
  line-height: 17px;
  display: block;
  color: #5B305D;
  font-weight: 800;
}

span.full-small-text {
  font-size: 14px;
  font-weight: 400;
  text-align: left;
  display: block;
  line-height: 15px;
  color: #5B305D;
}

span.year-small-txt {
  font-size: 16px;
  font-weight: 400;
  text-align: left;
  line-height: 18px;
  display: block;
  color: #5B305D;
}

p.footnotes-grid {
  font-size: 12px;
  line-height: 16px;
  text-align: left;
  padding: 10px 0 45px;
  color: #333333;
}

.grid-violator {
  position: absolute;
  right: 0px;
  top: 0;
}

.grid-violator.desktop-only {
  transform: translate(130%);
}

.dom-ready .grid-violator.desktop-only {
  transform: translate(75%);
  transition: all 1s ease-in-out;
  transition-delay: 0s;
}

img.grid-violator-img {
  width: 205px;
}

.pink-var {
  color: #FF00BA !important;
}

/*nccn block*/

.about.nccn-section {
  margin-top: 30px;
  /*margin-bottom: 30px;*/
  margin-bottom: 10px;
}

.purple-block .metastatic-nccn-icon {
  width: 100%;
  height: 90px;
  top: 10px;
}

.about.nccn-section .table-header {
  font-family: 'Barlow';
  font-size: 22px;
  text-align: center;
  line-height: 26px;
  color: #5B305D;
  font-weight: 700;
  padding: 14px 0 0;
  margin: 0;
  position: relative;
  top: -91px;
}

.grey-block.txt-ctr {
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/About%20Page%20NCCN%20Callout%20Graphic%20Bottom%20Desktop.png) no-repeat;
  min-height: 387px;
  margin: -108px 0px 0px 5px;
  background-size: 100% 95%;
  background-position: 0 0px;
  position: relative;
  left: -5px;
  width: 100%;
  padding-top: 17px;
  transform: translate(0, 100px);
  transition: 1s all ease-out;
}

.is-visible.grey-block.slide-to-top-nccn {
  transform: none;
  opacity: 1;
}

ul.nccn-tct {
  display: flex;
  justify-content: space-around;
  list-style-type: none !important;
  padding-left: 20px;
}

ul.nccn-tct li:not(:last-child)::after {
  content: ' ';
  width: 1px;
  display: block;
  position: absolute;
  right: -12px;
  height: 83%;
  top: 50px;
  border-right: 1px solid #5B305D;
}

/*nccn block*/

.isiNode ul.isi-list ul>li::before {
  content: '-';
  left: -13px;
  padding-left: 9px;
}

.ref.about-ref span.word-brk {
    word-break: normal;
}

/*  mobile view */

@media screen and (max-width: 767px) {

  .grid-container {
    grid-template-columns: repeat(2, 1fr);
    gap: 0 30px;
    padding: 0;
    margin: 10px -15px 0px;
  }

  .grid-container > :nth-child(-n+5) {
    margin-bottom: 0;
    align-self: start;
  }

  .grid-item {
    display: flex;
    flex-direction: column;
  }

  .related-item {
    margin: 8px 0 60px;
  }
  
    /* Reorder */
  .grid-container {
    display: grid;
    grid-template-areas: "a1 b1"
        "a2 b2"
        "a3 b3"
        "a4 b4"
        "a5 b5";
    max-width: 374px;
    margin: 0 auto;
    margin-top: 60px;
  }

  .grid-container > :nth-child(1) {
    grid-area: a5;
    margin-top: 0px;
  }

  .grid-container > :nth-child(2) {
    grid-area: a4;
  }

  .grid-container > :nth-child(3) {
    grid-area: a3;
    /*margin-top: 28px;*/
    margin-top: 9px;
  }

  .grid-container > :nth-child(4) {
    grid-area: a2;
    /*margin-top: 2px;*/
    margin-top: -1px;
    margin-left: -10px;
  }

  .grid-container > :nth-child(5) {
    grid-area: a1;
    margin-top: 4px;
  }

  .grid-container > :nth-child(6) {
    grid-area: b5;
    margin-top: 6px;
  }

  .grid-container > :nth-child(7) {
    grid-area: b4;
  }

  .grid-container > :nth-child(8) {
    grid-area: b3;
    /*margin-top: 34px;*/
    margin-top: 16px;
  }

  .grid-container > :nth-child(9) {
    grid-area: b2;
    /*margin-top: 17px;*/
    margin-top: 15px;
  }

  .grid-container > :nth-child(10) {
    grid-area: b1;
    margin-top: 10px;
  }

  #skiptomaincontent > div:nth-child(3) > div.component-section.full-width.no-style.bg-white.about-section > div.page-section-inner.container > div:nth-child(2) > div > div.grid-container > div:nth-child(9) > div {
    margin-top: -8px;
  }
  
    /* text */
    
  .indent-new {
    text-indent: -8px;
  }

  .indent-new2 {
    text-indent: -10px;
  }

  .top-percent-container {
    display: flex;
    flex-direction: column;
    row-gap: 10px;
  }

  span.year-txt {
    font-size: 34px;
    line-height: 29px;
    text-align: right;
    font-weight: 900;
    margin: 0px 0 4px;
  }

  span.year-small-txt {
    font-size: 13px;
    text-align: right;
    line-height: 22px;
  }

  span.year-small-txt.equalize-txt {
    line-height: 20px;
    max-width: 120px;
    margin-left: auto;
  }

  span.year-desc-txt {
    font-size: 15px;
    line-height: 22px;
    text-align: right;
  }

  span.percent-txt {
    font-size: 41px;
    line-height: 20px;
    text-align: left;
  }

  span.percent-txt {
    font-size: 41px;
    line-height: 20px;
  }

  span.full-desc-text {
    font-size: 15px;
    text-align: left;
    line-height: 17px;
  }

  span.full-note-text {
    font-size: 11px;
    line-height: 15px;
    text-align: left;
  }

  span.percent-desc-txt {
    font-size: 15px;
    line-height: 18px;
    font-weight: 800;
    color: #5B305D;
    text-align: left;
    display: block;
  }

  #skiptomaincontent > div:nth-child(3) > div.component-section.full-width.no-style.bg-white.about-section > div.page-section-inner.container > div:nth-child(2) > div > div.grid-container > div:nth-child(7) > div > span.percent-desc-txt {
    margin-top: -38px;
    margin-left: 48px;
  }

  span.full-small-text {
    font-size: 13px;
    line-height: 17px;
  }

  span.percent-symbol {
    position: relative;
    bottom: 7px;
  }
    

    /* line  */
  .line {
    top: 0;
    left: 50%;
    width: 1px;
    height: 1075px;
    transform: translateX(-50%);
  }

  .line.mapline.vertical {
    display: none !important;
  }

  .line-vertical {
    display: none !important;
  }

    /* circles */
  .circle {
    /*left: 48%;*/
    left: 47.3%;
    transform: translateX(-32%);
    top: 0;
  }

  .circle-1 {
    top: -45px;
  }

  .circle-2 {
    top: 179px;
  }

  .circle-3 {
    /*top: 439px;*/
    /*top: 38%;*/
    /*top: 39%;*/
    top: 38.3%;
 /*newly added (20-11-24)*/;
  }

  .circle-4 {
    /*top: 666px;*/
    top: 57%;
 /*newly added (20-11-24)*/;
  }

  .circle-5 {
    /*top: 872px;*/
    /*top: 77.5%;*/
 /*newly added (20-11-24)*/;
    top: 76.8%;
  }

  .circle-6 {
    /*top: 1071px;*/
    top: 97%;
 /*newly added (20-11-24)*/;
  }

  .line {
    height: 97%;
 /*newly added (20-11-24)*/;
  }

  .circle.circle-6 img.circle-img {
    transform: rotate(90deg);
  }
    /* violator */

  .grid-violator.mobile-only {
    display: inline-block;
        /*transform: translateX(0%);*/
    margin: -30px auto 14px;
    position: relative;
        /*left: 50%;*/
    ;
  }

  .about.home-about .grid-violator {
    margin-top: 10px;
    margin-bottom: 76px;
    margin-left: 0;
        /* margin-right: auto; */
        /* margin: 0 auto; */
    width: 100%;
  }

  .about.home-about img.grid-violator-img {
    width: 100%;
    transform: none;
    margin: 0 auto;
  }

  .dom-ready .grid-violator.mobile-only {
        /*transform: translate(-50%);*/
        /*transition: all 1s ease-in-out;*/
        /*transition-delay: 0s;*/
    transform: none;
    margin-top: 0px;
    margin-bottom: 50px;
  }

  img.grid-violator-img {
    width: 350px;
    transform: translateX(-10px);
  }
    /* footnote */
  p.footnotes-grid {
    font-size: 12px;
    line-height: 16px;
    text-align: left;
    padding: 0;
    color: #333333;
    margin: 0;
    margin-top: 40px;
  }

  .subhead3 {
    padding-top: 30px;
  }
}



/* recommendations table */
.recommendations-table--container {
  display: none;
  background-size: cover;
  background-repeat: no-repeat;
  background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/recommendations-table-bg.svg);
  width: 100%;
  height: 422px;
  margin: 25px auto 40px;
  position: relative;
  transition: 1s all ease-out;
  transform: translate(0, 100px);
}

.dom-ready .recommendations-table--container {
  transform: translate(0);
}

.recommendations-table--wrapper {
  display: flex;
  margin: 0 auto;
  justify-content: center;
}

h2.table-header {
  font-family: 'Barlow';
  font-size: 22px;
  text-align: center;
  line-height: 26px;
  color: #5B305D;
  font-weight: 700;
  padding: 14px 0 0;
  margin: 0;
}

p.table-col-txt {
  font-family: 'Barlow';
  font-size: 16px;
  color: #5B305D;
  line-height: 20px;
  text-align: left;
}

.recommendations-table--col {
  margin: 45px 0 0;
  margin-right: 30px;
}

.recommendations-table--col:last-child {
  margin-right: 0;
}

/* columns */
.col-1 {
  width: 149px;
}

.col-2 {
  width: 185px;
}

.col-3 {
  width: 169px;
}

.col-4 {
  width: 168px;
}

/* lines */
.recommendations-table--col {
  position: relative;
}

.recommendations-table--col:not(:last-child)::after {
  content: ' ';
  width: 1px;
  display: block;
  position: absolute;
  right: -12px;
  height: 97%;
  top: 0;
  border-right: 1px solid #5B305D;
}

.recommendations-table--footer {
  margin: 0px 0 30px;
}

/* violator */

.table-violator {
    position: absolute;
    left: 40px;
    /* top: 15px; */
    top: 6px;
    /* transform: translate(-90%); */
    transform: translate(-270%);
}

.table-violator.is-visible {
  transform: translate(-46%);
}

/*.table-violator:before {*/
/*  content: '[';*/
/*  position: relative;*/
/*  left: 125px;*/
/*  top: 7px;*/
/*  color: #ff00ba;*/
/*  font-size: 49px;*/
/*  z-index: 1;*/
/*  scale: 1;*/
/*}*/

/*.table-violator:after {*/
/*  content: ']';*/
/*  position: relative;*/
/*  left: -130px;*/
/*  top: -8px;*/
/*  color: #ff00ba;*/
/*  font-size: 49px;*/
/*  z-index: 1;*/
/*  scale: 1;*/
/*}*/

img.table-violator-img {
  width: 150px;
  height: auto;
  overflow: hidden;
}

.home-about .is-visible .table-violator {
  transform: translate(100%);
  transition: all 1s ease-in-out;
  transition-delay: 0s;
}
.home-about .table-violator {
    display:none;
}
/* mobile view */
@media screen and (max-width: 400px) {
    .table-violator {
        top: 305px;
    }
}

@media screen and (max-width: 768px) {

  .recommendations-table--container {
    background-size: auto;
    background-repeat: no-repeat;
    background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/recommendations-table-bg-mobile.svg);
    width: 270px;
    height: 930px;
    margin: 0 auto;
    position: relative;
    transition: 1s all ease-out;
    transform: translate(0, 100px);
  }

  .dom-ready .recommendations-table--container {
    transform: translate(0);
  }

  .recommendations-table--wrapper {
    display: flex;
    margin: 0 auto;
    justify-content: center;
    flex-direction: column;
  }

  .recommendations-table--col {
    position: relative;
    width: 100%;
    margin: 20px 0 0 0;
    /*padding: 0 17px;*/
    padding: 0px;
  }

  .recommendations-table--col:not(:last-child)::after {
    content: none;
  }

  .recommendations-table--col:not(:first-child)::after {
    content: ' ';
    width: 60%;
    display: block;
    position: absolute;
    right: 0;
    left: 0;
    height: 1px;
    top: -15px;
    border-bottom: 1px solid #5B305D;
    border-right: none;
    transform: translateX(30%);
  }

  h2.table-header {
    font-size: 18px;
    line-height: 22px;
    text-align: center;
    padding: 14px 0 0;
    margin: 0 0 35px;
  }

  .table-violator {
    position: absolute;
    left: 15px;
    /* top: 305px; */
    /* top: 147px; */
    top: 241px;
    transform: translate(-46%);
  }
    
    /*.dom-ready .table-violator {*/
    /*    transform: none;*/
    /*}*/
  img.table-violator-img {
    /*width: 110px;*/
    width: 150px;
    height: auto;
    overflow: hidden;
    z-index: 99;
    position: relative;
    transform: rotate(-2deg);
  }

  .home-about .is-visible .table-violator {
        /*transform: translate(-46%);
        transition: all 1s ease-in-out;
        transition-delay: 0s;*/
        /*transform: none;*/
    ;
        transform: translate(-53%);
  }

  .recommendations-table--footer {
    margin: 30px 0 30px;
  }

  /*.table-violator:before {*/
  /*  content: '[';*/
  /*  position: relative;*/
  /*  left: 121px;*/
  /*  top: 7px;*/
  /*  color: #ff00ba;*/
  /*  font-size: 49px;*/
  /*  z-index: 1;*/
  /*  scale: 1;*/
  /*}*/

  /*.table-violator:after {*/
  /*  content: ']';*/
  /*  position: relative;*/
  /*  left: 53px;*/
  /*  top: -118px;*/
  /*  color: #ff00ba;*/
  /*  font-size: 49px;*/
  /*  z-index: 1;*/
  /*  scale: 1;*/
  /*}*/;
}


/* recommendations table end */




/* updates */

.about .ref a.refer-link {
  text-decoration: none !important;
}

.about .multi-column-container.map {
  position: relative;
  margin: 15px 0 75px;
}

.about .pill-sec {
  display: inline-flex;
  margin: 40px auto 0;
}

@media screen and (max-width: 768px) {
  .about .multi-column-container.map {
    position: relative;
    margin: 0px 0 0px;
  }

  .mob-fix-width {
    width: 101%;
  }

  h2.subhead.subhead3.slide-to-top.mt-0.mob-fix-width.is-visible {
    padding: 0 0 20px;
  }

  /*.grid-container .circle {*/
  /*  left: 47.6%;*/
  /*}*/
}

@media screen and (min-width: 351px) and (max-width: 768px) {
  .grid-container .circle-6 {
    top: 97%;
  }
}

/* updates end */
/*.footnotes, p.footnotes.double-footnotes.footnote-osimertinib{*/
/*    padding-left:0px;*/
/*    text-indent:0;*/
/*}*/
/*.footnotes sup:nth-child(1){*/
/*    margin-left:-6px;*/
/*}*/


/*.violator-os-data {*/
/*    position: absolute;*/
/*    right: -208px;*/
/*    top: -20px;*/
/*    background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/violator-os-data-desktop.png);*/
/*    width: 170%;*/
/*    height: 100%;*/
/*    background-repeat: no-repeat;*/
/*    background-size: cover;*/
/*    cursor: pointer;*/
/*}*/
/* .violator-os-data:hover {*/
/*    background-image: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/violator-os-data-hover-desktop.png);*/
/*}*/



.violator-os-data-txt {
  text-align: center;
  font-size: 18px;
  color: #5B305D;
  font-weight: 800 !important;
  position: absolute;
  right: 39px;
  top: 11px;
  text-indent: 4px;
}

.about .violator-os-data {
  position: absolute;
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/New-OS-Data-Desktop.png) no-repeat;
  background-size: 100% 100%;
    /* width: 180px; */
    /* height: 75.5px; */
  width: 219px;
  height: 91.5px;
  position: absolute;
    /* right: -230px; */
  right: -427px;
    /* top: -20px; */
  top: -46px;
  cursor: pointer;
}

.sp-n-2 {
  font-size: 14px;
  top: -0.08em;
}

.sp-left-2 {
  margin-left: -2px;
}

.about .violator-os-data:hover {
  position: absolute;
  background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/New-OS-Data-Green-Desktop.png) no-repeat;
  background-size: 100% 100%;
  width: 219px;
  height: 91.5px;
  position: absolute;
  right: -427px;
    /* top: -20px; */
  top: -46px;
  cursor: pointer;
}

.violator-os-data:hover .violator-os-data-txt {
  color: #ffffff;
}

.mobile-only .about-banner-map-txt {
  position: relative;
  left: 3px;
  max-width: 280px;
  position: relative;
  top: -232px;
  right: 0;
  text-align: left;
  margin: 0 auto;
  line-height: 15px;
}

.mobile-only.about-banner-map {
  width: 300px;
}

.mobile-only.about-banner-footnotes {
  margin-top: -175px;
}

/*#skiptomaincontent > div:nth-child(3) > div.component-section.full-width.no-style.bg-white.about-section > div.page-section-inner.container > div:nth-child(2) > div > div.mob-acc.purple-txt.mobile-only > div.acc-right-block.year-desc.yr-2-desc.in {*/
/*    width: 170px;*/
/*    position: relative;*/
/*    left: 166px;*/
/*}*/

@media screen and (min-width: 992px) {
    .about .isi-wrapper.open {
        padding-top: 0px;
        margin-top: -12px;
    }
  .is-visible.eyebrow, h1.is-visible, h2.is-visible, .is-visible.subhead {
    max-width: 800px;
  }

  h2.is-visible, .is-visible.subhead {
    padding-top: 23px;
  }

  .yr-1-head {
    margin-left: -43px;
  }

  .about .pill-sec.is-visible .caps-pill {
    margin-bottom: 0;
  }
/*.violator-os-data{*/
/*        transition: 1.25s ease;*/
/*}*/
  .extrabold.pcent-right {
    top: -1px;
  }

  .year-desc .yr-desc-wrap > div.in {
    visibility: visible;
  }

  .year-desc .yr-desc-wrap > div {
    visibility: hidden;
    display: block;
    height: 170px !important;
  }

  .yr-desc-wrap .collapsed span:after {
    content: "+";
  }

  .about .year-desc {
    max-width: 574px;
  }

  .about .year-desc .yr-desc-wrap > div {
    padding: 18px 12px 10px 16px;
    width: 178px;
  }

  .year-desc {
    padding-left: 0 !important;
    left: -10px;
  }

  .about .nccn-sec .nccn-content {
    margin: 92px auto 35px;
  }

  .about .hr-greyline {
    width: 86%;
  }
}
/*about page styling end*/
/*@media screen and (max-width: 991px){*/
/*.about .mobile-only.about-banner-chevron-map{*/
/*        width: 269px;*/
/*    position: relative;*/
/*    left: 0px;*/
/*    top: 37px;*/
/*}*/
/*.about .mobile-only.about-banner-map{*/
/*        width: 269px;*/
/*    height: 320px;*/
/*    position: relative;*/
/*    left: 0px;*/
/*    top: 16px;*/
/*}*/
/*.about .mobile-only .about-banner-map-txt{*/
/*        position: relative;*/
/*    left: -2px;*/
/*    max-width: 234px;*/
/*    position: relative;*/
/*    top: -245px;*/
/*    right: 0;*/
/*    text-align: left;*/
/*    margin: 0 auto;*/
/*    line-height: 15px;*/
/*}*/
/*.violator-os-data::before{*/
/*        color: #FF00BA !important;*/
/*    content: "[";*/
/*    position: relative;*/
/*    font-size: 102px;*/
/*    left: -101px;*/
/*    top: 22px;*/
/*    font-family: system-ui !important;*/
/*    font-weight: 100 !important;*/
/*}*/
/*.violator-os-data::after{*/
/*         color: #FF00BA !important;*/
/*    content: "]";*/
/*    position: relative;*/
/*    font-size: 102px;*/
/*    right: -98px;*/
/*    top: 22px;*/
/*    font-family: system-ui !important;*/
/*    font-weight: 100 !important;*/
/*}*/
/*    .year-head .bold {*/
/*    font-size: 22px;*/
/*}*/
/*.yr-2-desc .extrabold {*/
/*    top: -7px;*/
/*}*/
/*.headline {*/
/*    margin: 30px 0 0 0;*/
/*}*/
/*.about .section-heading-mobile {*/
/*    top: 54px;*/
/*}*/
/*p.numbertick {*/
/*    margin-left: -12px;*/
/*}*/
/*.small-txt {*/
/*    margin-bottom: 20px;*/
/*    padding-top: 10px;*/
/*}*/
/*.acc-img-block div.collapsed img.clpsed {*/
/*    display: inline-block;*/
/*}*/

/*.acc-img-block div img.clpsed-close {*/
/*    display: inline-block;*/
/*}*/

/*img.clpsed, .acc-img-block div.collapsed img.clpsed-close, .acc-img-block div img.clpsed {*/
/*    display: none;*/
/*}*/
/*.year-head{*/
/*    line-height: 22px;*/
/*}*/
/*.pill-sec {*/
/*    flex-direction: column;*/
/*    margin: 20px auto 5px;*/

/*}*/
/*.pill-img, .nccn-img {*/
/*    text-align: center;*/
/*}*/
/*.lung-line {*/
/*    text-align: center;*/
/*    position: relative;*/
/*}*/
/*.lung-line:after {*/
    /*content: "";*/
    /*position: absolute;*/
    /*border-right: 1px solid;*/
    /*left: 0;*/
    /*right: 0;*/
    /*top: 86px;*/
    /*width: 2px;*/
    /*height: 640px;*/
    /*height: 683px;*/
    /*margin: 0 auto;*/
/*        content: "";*/
/*    position: absolute;*/
/*    border-right: 1px solid;*/
/*    left: 0;*/
/*    right: 0;*/
/*    top: 114px;*/
/*    width: 2px;*/
/*    height: 658px;*/
    /* height: 683px; */
/*    margin: 0 auto;*/
/*}*/

/*.mobile-only.violator-os-data {*/
/*    position: absolute;*/
/*    right: 60px;*/
/*    top: -60px;*/
/*      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/New-OS-Data-Mobile.png) no-repeat;*/
/*    background-size: 100% 100%;*/
/*    background-position:center;*/
/*    width: 219px;*/
/*    height: 91.5px;*/
/*    cursor: pointer;*/
    
/*}*/
/*.mobile-only.violator-os-data:hover {*/
/*    position: absolute;*/
/*    right: 60px;*/
/*    top: -60px;*/
/*      background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/New-OS-Data-Green-Mobile.png) no-repeat;*/
/*    background-size: 100% 100%;*/
/*    background-position:center;*/
/*    width: 219px;*/
/*    height: 91.5px;*/
/*    cursor: pointer;*/
    
/*}*/
/*.about .lung-line img{*/
/*       margin-top: 30px;*/
/*}*/

/*.mobile-only.violator-os-data-txt {*/
/*    text-align: center;*/
/*    font-size: 18px;*/
/*    color: #5B305D;*/
/*    font-weight: 800 !important;*/
/*    position: absolute;*/
/*    right: 75px;*/
/*    top: 15px;*/
/*}*/

/*.mob-acc {*/
    /*margin: 0 auto 40px auto;*/
    /*max-width: 375px;*/
/*    margin: 0 auto 12px auto;*/
/*}*/
/*.numbertick img {*/
/*    max-width: 353px;*/
/*    margin: 0 0 0 -20px;*/
/*    padding-top: 12px;*/
/*}*/
/*.acc1-block {*/
/*    display: inline-flex;*/
/*    margin-top:25px;*/
/*}*/
/*.acc-left-block.year-head {*/
/*    width: 80%;*/
/*    text-align: right;*/
/*        right: -12px;*/
/*    position: relative;*/
/*}*/
/*.acc-img-block {*/
/*    width: 25%;*/
/*    text-align: center;*/
/*    z-index: 0;*/
/*    margin: 20px 0 0 10px;*/
/*    position: relative;*/
/*    left: 13px;*/
/*}*/
/*.acc-right-block.year-desc {*/
/*    text-align: left;*/
/*    padding: 15px 2px 15px 22px !important;*/
/*    border-radius: 0 12px 12px 0;*/
/*    box-shadow: 3px 3px 6px #00000052;*/
/*}*/
/*.year-head, .year-desc {*/
/*    display: inline-block;*/
/*    margin-left: 2px;*/
/*    padding-top: 17px;*/
/*}*/
/*.year-head{*/
/*    padding-top:12px;*/
/*}*/

/*.yr-desc-wrap > .year-desc.in {*/
/*    visibility: visible;*/
/*}*/
/*.yr-desc-wrap > .year-desc{*/
/*    visibility:hidden;*/
/*    display: block;*/
/*    height:176px !important;*/
/*}*/
/*.yr-1-desc, .yr-2-desc {*/
/*    margin-right: 0px;*/
/*    margin-left: 7px;*/
/*}*/
/*.green-down-arrow img {*/
/*    position: relative;*/
/*    z-index: 0;*/
/*    top:20px;*/
/*    left:1px;*/
/*}*/

/*.map .columnControl.section .column-1{*/
/*    padding:0;*/
/*}*/
/*.subhead3 {*/
/*    padding-top: 55px;*/
/*}*/
/*.nccn-sec {*/
/*    flex-direction: column;*/
/*}*/
/*.nccn-content {*/
/*    margin-top: 16px;*/
/*} */
/*p.map-animate {*/
/*    max-width: 420px;*/
/*    margin: 0 auto 60px;*/
/*    left: 8px;*/
/*}*/
/*.is-visible .vr-line-map {*/
/*    display: block !important;*/
/*    height: 68px;*/
    /*left: 50%;*/
/*    left: 49%;*/
/*    top: 87%;*/
/*}*/
/*.is-visible .vr-line-map:after {*/
/*    width: 0;*/
/*}*/
/*.year-desc .extrabold {*/
/*    font-size: 15px;*/
/*    line-height: 17px;*/

/*}*/
/*.yr-2-desc .extrabold {*/
/*    margin-right: 10px;*/
/*}*/
/*.yr-3-desc .extrabold.pcent{*/
/*    padding-top: 0px;*/
/*}*/
/*.year-desc .vs-txt {*/
/*    font-size: 13px !important;*/
/*    line-height: 17px !important;*/
/*}*/
/*.year-desc .pcent-right {*/
/*    font-size: 17px;*/
/*    line-height: 19px;*/
/*}*/
/*.mob-acc .acc1-block:nth-child(2) .acc-img-block, .mob-acc .acc1-block:nth-child(3) .acc-img-block,.mob-acc .acc1-block:nth-child(4) .acc-img-block {*/
/*    margin-right: -22px;*/
/*    left:3px;*/
/*    top:-6px;*/
/*}*/
/* .mob-acc .acc1-block:nth-child(4) {*/
/*   left:5px;*/
/*}*/
/*.mob-acc .acc1-block:nth-child(5) .acc-img-block {*/
/*   left:16px; */
/*   top:-8px;*/
/*}*/
/*.acc-right-block.year-desc.yr-3-desc {*/
/*    padding: 15px 3px 15px 15px !important;*/
/*}*/
/*.acc-right-block.year-desc.yr-1-desc {*/
    /*padding: 18px 7px 15px 22px !important;*/
      /*padding:18px 7px 15px 17px !important;*/
      /*  margin-left: 11px;*/
          /* padding: 18px 7px 15px 22px !important; */
/*    padding: 18px 7px 15px 15px !important;*/
/*    margin-left: 10px;*/
/*}*/
/*.acc-right-block.year-desc.yr-2-desc {*/
/*    padding: 15px 2px 15px 15px!important;*/
  
/*    width: 162px;*/
/*    margin-left: 173px;*/
/*    margin-top: -85px;*/
/*}*/
/*.about .year-desc .ffb-med {*/
/*    font-size: 11px;*/
/*    line-height: 15px;*/
/*}*/
/*.year2.acc-img-block {*/
/*        margin-right: -22px;*/
/*    left: 1px;*/
/*    top: -6px;*/
/*}*/
/*.acc-right-block.year-desc.yr-3-desc {*/
/*    margin-left: 0px;*/
/*    padding: 15px 2px 15px 15px !important;*/
/*}*/
/*.about-section .columnControl.section .column-2 {*/
/*    padding: 0;*/
/*}*/
/*}*/
/*about page styling end*/
@media screen and (max-width: 991px) {
  .about .mobile-only.about-banner-chevron-map {
    width: 269px;
    position: relative;
    left: 0px;
    top: 37px;
  }

  .about .mobile-only.about-banner-map {
    width: 269px;
    height: 320px;
    position: relative;
    left: 0px;
    top: 16px;
  }
  


  .about .mobile-only .about-banner-map-txt {
    position: relative;
    left: -2px;
    /*max-width: 234px;*/
    max-width: 230px;
    position: relative;
    top: -245px;
    right: 0;
    text-align: left;
    margin: 0 auto;
    line-height: 15px;
  }

  .about .about-banner-footnote-container > p.purple-txt:first-child {
    margin-bottom: 10px;
  }

  .home-about .pill-img.slide-frm-left {
    transform: translate(0);
    transition: none;
  }

  .home-about h2.slide-frm-right {
    transform: translate(0);
    transition: none;
  }

  .home-about .is-visible .pill-img.slide-frm-left {
    transform: none;
  }

  .home-about .is-visible h2.slide-frm-right {
    transform: none;
  }

  .violator-os-data::before {
    color: #FF00BA !important;
    content: "[";
    position: relative;
    font-size: 102px;
    left: -101px;
    top: 22px;
    font-family: system-ui !important;
    font-weight: 100 !important;
  }

  .violator-os-data::after {
    color: #FF00BA !important;
    content: "]";
    position: relative;
    font-size: 102px;
    right: -98px;
    top: 22px;
    font-family: system-ui !important;
    font-weight: 100 !important;
  }

  .year-head .bold {
    font-size: 22px;
  }

  .yr-2-desc .extrabold {
    top: -7px;
  }

  .headline {
    margin: 30px 0 0 0;
  }

  .about .section-heading-mobile {
    top: 54px;
  }

  p.numbertick {
    margin-left: -12px;
  }

  .small-txt {
    margin-bottom: 20px;
    padding-top: 10px;
  }

  .acc-img-block div.collapsed img.clpsed {
    display: inline-block;
  }

  .acc-img-block div img.clpsed-close {
    display: inline-block;
  }

  img.clpsed, .acc-img-block div.collapsed img.clpsed-close, .acc-img-block div img.clpsed {
    display: none;
  }

  .year-head {
    line-height: 22px;
  }

  .pill-sec {
    flex-direction: column;
    margin: 20px auto 5px;
  }

  .pill-img, .nccn-img {
    text-align: center;
  }

  .lung-line {
    text-align: center;
    position: relative;
  }

  .lung-line:after {
    /*content: "";*/
    /*position: absolute;*/
    /*border-right: 1px solid;*/
    /*left: 0;*/
    /*right: 0;*/
    /*top: 86px;*/
    /*width: 2px;*/
    /*height: 640px;*/
    /*height: 683px;*/
    /*margin: 0 auto;*/
    content: "";
    position: absolute;
    border-right: 1px solid;
    left: 0;
    right: 0;
    top: 114px;
    width: 2px;
    height: 673px;
    /* height: 683px; */
    margin: 0 auto;
  }

  .mobile-only.violator-os-data {
    position: absolute;
    right: 60px;
    top: -60px;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/New-OS-Data-Mobile.png) no-repeat;
    background-size: 100% 100%;
    background-position: center;
    width: 219px;
    height: 91.5px;
    cursor: pointer;
  }

  .mobile-only.violator-os-data:hover {
    position: absolute;
    right: 60px;
    top: -60px;
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/mobile/New-OS-Data-Green-Mobile.png) no-repeat;
    background-size: 100% 100%;
    background-position: center;
    width: 219px;
    height: 91.5px;
    cursor: pointer;
  }

  .about .lung-line img {
    margin-top: 30px;
  }

/*nccn block*/
  .about.nccn-section {
    padding-left: 30px;
    padding-right: 30px;
  }

  .grey-block.txt-ctr {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/About%20Page%20NCCN%20Callout%20Graphic%20Bottom%20Mobile.png) no-repeat;
    min-height: 387px;
    /*margin: -93px 0px 0px 5px;*/
    margin: -99px 0px 0px 5px;
    background-size: 99% 100%;
    background-position: 0 0px;
    position: relative;
    left: -5px;
    width: 100%;
    padding-top: 35px;
    padding-right: 5px;
  }

  .about.nccn-section .table-header {
    font-family: 'Barlow';
    font-size: 18px;
    text-align: center;
    line-height: 22px;
    color: #5B305D;
    font-weight: 700;
    padding: 14px 0 0;
    margin: 0;
    position: relative;
    top: -95px;
  }

  ul.nccn-tct {
    display: flex;
    justify-content: space-around;
    list-style-type: none !important;
    padding-left: 20px;
    flex-direction: column;
  }

  ul.nccn-tct li:first-child::after {
    border-right: none;
  }

  ul.nccn-tct li:not(:first-child)::after {
    content: ' ';
    width: 60%;
    display: block;
    position: absolute;
    right: 0;
    left: 0;
    height: 1px;
    top: 0px;
    border-bottom: 1px solid #5B305D;
    border-right: none;
    transform: translateX(30%);
  }
/*nccn block*/

/*.mobile-only.violator-os-data-txt {*/
/*    text-align: center;*/
/*    font-size: 18px;*/
/*    color: #5B305D;*/
/*    font-weight: 800 !important;*/
/*    position: absolute;*/
/*    right: 75px;*/
/*    top: 15px;*/
/*}*/

  .mob-acc {
    /*margin: 0 auto 40px auto;*/
    /*max-width: 375px;*/
    margin: 0 auto 12px auto;
  }

  .numbertick img {
    max-width: 353px;
    margin: 0 0 0 -20px;
    padding-top: 12px;
  }

  .acc1-block {
    display: inline-flex;
    margin-top: 25px;
  }

  .acc-left-block.year-head {
    width: 80%;
    text-align: right;
    right: -12px;
    position: relative;
  }

  .acc-img-block {
    width: 25%;
    text-align: center;
    z-index: 0;
    margin: 20px 0 0 10px;
    position: relative;
    left: 13px;
  }

  .acc-right-block.year-desc {
    text-align: left;
    padding: 15px 2px 15px 22px !important;
    border-radius: 0 12px 12px 0;
    box-shadow: 3px 3px 6px #00000052;
  }

  .year-head, .year-desc {
    display: inline-block;
    margin-left: 2px;
    padding-top: 17px;
  }

  .year-head {
    padding-top: 12px;
  }

  .yr-desc-wrap > .year-desc.in {
    visibility: visible;
  }

  .yr-desc-wrap > .year-desc {
    visibility: hidden;
    display: block;
    height: 176px !important;
  }

  .yr-1-desc, .yr-2-desc {
    margin-right: 0px;
    margin-left: 7px;
  }

  .green-down-arrow img {
    position: relative;
    z-index: 0;
    top: 20px;
    left: 1px;
  }

  .map .columnControl.section .column-1 {
    padding: 0;
  }

  .subhead3 {
    padding-top: 25px;
  }

  .nccn-sec {
    flex-direction: column;
  }

  .nccn-content {
    margin-top: 16px;
  }

  p.map-animate {
    left: 0px;
    max-width: 420px;
    margin: 0 auto 60px;
    transform: scale(1.05);
    transform-origin: center;
  }

  .is-visible .vr-line-map {
    display: block !important;
    height: 48px;
    /*left: 50%;*/
    left: 49%;
    top: 100%;
  }
/*.is-visible .vr-line-map:after {*/
/*    width: 0;*/
/*}*/
  .year-desc .extrabold {
    font-size: 15px;
    line-height: 17px;
  }

  .yr-2-desc .extrabold {
    margin-right: 10px;
  }

  .yr-3-desc .extrabold.pcent {
    padding-top: 0px;
  }

  .year-desc .vs-txt {
    font-size: 13px !important;
    line-height: 17px !important;
  }

  .year-desc .pcent-right {
    font-size: 17px;
    line-height: 19px;
  }

  .mob-acc .acc1-block:nth-child(2) .acc-img-block, .mob-acc .acc1-block:nth-child(3) .acc-img-block,.mob-acc .acc1-block:nth-child(4) .acc-img-block {
    margin-right: -22px;
    left: 3px;
    top: -6px;
  }

  .mob-acc .acc1-block:nth-child(4) {
    /*left:6px; */
    ;
  }

  .mob-acc .acc1-block:nth-child(4) .acc-img-block {
    left: 6px!important;
  }

  .mob-acc .acc1-block:nth-child(5) .acc-img-block {
    left: 16px;
    top: -8px;
  }

  .mob-acc .acc1-block:nth-child(4) .acc-left-block.year-head {
    right: -2px;
  }

  .mob-acc .acc1-block:nth-child(3) .acc-left-block.year-head {
    right: 2px;
  }

  .mob-acc .acc1-block:nth-child(3) .acc-img-block {
    left: 0px;
  }

  .acc-right-block.year-desc.yr-3-desc {
    padding: 15px 3px 15px 15px !important;
  }

  .acc-right-block.year-desc.yr-1-desc {
    /*padding: 18px 7px 15px 22px !important;*/
    /*padding:18px 7px 15px 17px !important;*/
    /*  margin-left: 11px;*/
    /* padding: 18px 7px 15px 22px !important; */
    padding: 18px 7px 15px 15px !important;
    margin-left: 10px;
  }

  .acc-right-block.year-desc.yr-2-desc {
    padding: 18px 10px 15px 16px !important;
    /* width: 285px; */
    /* margin-left: 32px; */
    margin-top: 1px;
    /* padding: 18px 7px 15px 22px !important; */
    /* padding: 18px 7px 15px 17px !important; */
    /* margin-left: 11px; */
    /* padding: 18px 7px 15px 22px !important; */
    padding: 18px 7px 15px 15px !important;
    margin-left: 15px;
  }

  .about .year-desc .ffb-med {
    font-size: 11px;
    line-height: 15px;
  }

  .year2.acc-img-block {
    margin-right: -22px;
    left: 1px;
    top: -6px;
  }

  .acc-right-block.year-desc.yr-3-desc {
    margin-left: 0px;
    padding: 15px 2px 15px 15px !important;
  }

  .about-section .columnControl.section .column-2 {
    padding: 0;
  }
}

@media screen and (min-width: 992px) {
  p.footnotes.indent-new {
    text-indent: -7px;
  }

  .footnotes.indent-new.indent-new2 {
    text-indent: -10px;
    margin-left: 2px;
  }

  .acc-right-block.year-desc.yr-3-desc {
    margin-left: -10px;
    padding: 15px 2px 15px 25px !important;
  }

  .year-desc {
    margin-top: -38px;
    position: relative;
  }

  span.circle-line {
    font-size: 0px;
    height: 0px;
  }

  .acc-right-block.year-desc.yr-2-desc {
    padding: 15px 2px 15px 15px !important;
  }

  .circle-line:after {
    position: absolute;
    width: 27px;
    height: 27px;
    top: -15px;
    background: #5b305d;
    border-radius: 50%;
    text-align: center;
    color: #fff;
    font-size: 40px;
    font-family: 'Barlow';
    font-weight: 600;
    left: 5px;
    line-height: 21px;
    content: "-";
    transition: linear;
    transition-delay: 1s;
  }

  .lung-line {
    margin-top: -28px;
  }

  .hr-greyline {
    border-top: 2px solid #707070;
    width: 88%;
    display: inline-block;
    position: relative;
  }

  .hr-greyline:after {
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/global/arrow-green.svg) no-repeat left top;
    content: "";
    position: absolute;
    width: 27px;
    height: 27px;
    right: 0;
    top: -15px;
  }

  .vr-line-purple {
    width: 2px;
    height: 0px;
    background: #707070;
    position: absolute;
    right: -8px;
    transition: 2s ease;
    /*top: 10px;*/
    z-index: 2;
    top: 192px;
    /*right: -18px;*/
    /*right: 3px;*/
    ;
  }

/*.is-visible .vr-line-purple {*/
/*    height: 434px;*/
/*    right: -11px;*/
/*}*/

  .vr-line-purple:after {
    background: #707070;
    position: absolute;
    content: "";
    width: 0;
    height: 2px;
    bottom: 0;
    right: 0;
    transition: 1s ease;
    transition-delay: 2s;
  }

  .is-visible .vr-line-purple {
    height: 470px;
    right: -8px;
  }

  .is-visible .vr-line-purple:after {
    /*width: 43px;*/
    width: 105px;
  }
/*.is-visible .circle-line:after{ animation: changetominus 1s linear forwards; animation-delay: 1s}*/

/* Animations */
  .about-section {
    overflow-x: hidden;
  }

  .r-cta {
    transform: translateX(-100%);
  }

  .m-cta {
    transform: translateX(100%);
  }

  .r-cta, .m-cta {
    transition: 1s ease;
  }

  .is-visible .r-cta, .is-visible .m-cta {
    transform: translateX(0%);
  }

  .violator-os-data {
    transform: translateX(0);
    transition: 1;
    animation-delay: 2s !important;
    animation: slide-out 1.25s ease-in-out forwards;
    animation-fill-mode: forwards;
    transition: 1.25s all cubic-bezier(0, 0, 0, 0.79);
    transform: none;
    opacity: 1;
  }

  .violator-os-data::before {
    color: #FF00BA !important;
    content: "[";
    position: relative;
    font-size: 96px;
    left: -16px;
    top: 19px;
    font-family: system-ui !important;
    font-weight: 100 !important;
  }

  .violator-os-data::after {
    color: #FF00BA !important;
    content: "]";
    position: relative;
    font-size: 96px;
    right: -170px;
    top: 19px;
    font-family: system-ui !important;
    font-weight: 100 !important;
  }

  .numbertick {
    max-width: 353px;
    position: relative;
    top: 40px;
    left: -15px;
  }

  .numbertick:before {
    content: "";
    width: 75px;
    height: 2px;
    background: #909090;
    z-index: 9;
    position: absolute;
    /*left: -39px;*/
    left: -57px;
    top: 0;
    bottom: 0;
    margin: auto;
  }

  .is-visible p.numbertick:after {
   /* content: "";
    background: url(/content/dam/open-digital/tagrisso-hcp/us/en/desktop/numbertickup.gif);
    width: 100%;
    height: 100%;
    position: absolute;
    left: 0;
    top:0;*/
    ;
  }
}

/*@keyframes changetominus {
  0% {
    content: "+";
  }

  100% {
   content: "-";
  }
}*/

br.tablet-break {
  display: none;
}

@media only screen and (min-width: 768px) and (max-width: 769px) {
    .circle-1 {
        left: 0%;
    }
    .circle-2 {
        left: 20%;
    }
    .circle-3 {
        left: 40%;
    }
    .circle-4 {
        left: 60%;
    }
    .circle-5 {
        left: 80%;
    }
    .grid-container .circle-6 {
        /*top: 39%;*/
        top: 39.2%;
        left: 95% !important;
    }
}

@media screen and (min-width: 768px) and (max-width: 1023px) {
  br.tablet-break {
    display: block;
  }

  .yr-desc-wrap > .year-desc .yr-1-desc {
    height: 147px !important;
  }
}

@media screen and (min-width: 992px) and (max-width: 1024px) {
  .multi-column-container.map .col-lg-6.col-md-12.column-1, .multi-column-container.map .col-lg-6.col-md-12.column-2 {
    width: 50%;
  }
}

@media screen and (min-width: 1024px) and (max-width: 1199px) {
  .map .column-1, .map .column-2 {
    width: 50%;
  }
}

@media screen and (min-width: 768px) and (max-width: 1024px) {
  p.footnotes.footnote-ipad-text {
    text-indent: -7px;
    padding-left: 2px;
  }

  p.footnotes.double-footnotes.footnote-osimertinib.footnote-ipad-text-one {
    text-indent: -9px;
    padding-left: 1px;
  }

  p.footnotes.double-footnotes.footnote-osimertinib.footnote-ipad-text-two {
    text-indent: -9px;
    padding-left: 2px;
  }

  sup.text-two-sup {
    top: -0.8em;
  }
}

@media screen and (min-width: 320px) and (max-width: 1037px) {
    p.footnotes-grid {
        text-align: center;
    }
}

@media screen and (min-width: 320px) and (max-width: 345px) {
  .yr-desc-wrap > .year-desc {
    height: 190px !important;
  }

  .lung-line:after {
    height: 715px;
  }

  .numbertick img {
    max-width: 300px;
  }

  .acc-right-block.year-desc.yr-1-desc, .acc-right-block.year-desc.yr-2-desc, .acc-right-block.year-desc.yr-3-desc {
    padding-left: 15px !important;
  }

  .about.nccn-section .table-header {
    font-family: 'Barlow';
    font-size: 14px;
  }
}

@media screen and (max-width: 374px) {
                            
  .about .year-desc .ffb-med {
    font-size: 9.5px;
    max-width: 120px;
  }

  .about .yr3txt {
    right: -27px;
  }

  .year-desc .extrabold {
    font-size: 13.5px;
  }

  .about .mob-acc {
    width: 280px;
  }

  .about.nccn-section .table-header {
    font-family: 'Barlow';
    font-size: 14px;
  }

  .yr-2-desc .extrabold {
    margin-right: 5px;
    font-size: 12px;
  }

  .about .year-head .bold {
    font-size: 20px;
  }

  .about .acc-left-block.year-head {
    margin-left: -9px;
  }

  .yr-2-desc .extrabold {
    font-size: 12px;
  }

  .acc-right-block.year-desc.yr-3-desc {
    margin-left: 15px;
  }
}
/*@media screen and (min-width: 414px) and (max-width: 992px) {*/
/*  .acc-right-block.year-desc.yr-1-desc {*/
/*    margin-left: 22px;*/
/*}*/
/* .mob-acc .acc1-block:nth-child(3) .acc-img-block {*/
/*    left: 20px;*/
/*}*/
.mob-acc .acc1-block:nth-child(4) .acc-img-block {
  left: 12px;
}

.mob-acc .acc1-block:nth-child(5) .acc-img-block {
  left: 14px;
}
/*.acc-right-block.year-desc.yr-2-desc {*/
/*    padding: 18px 10px 15px 26px !important;*/
/*}*/

.acc-right-block.year-desc .ffb-med {
  max-width: 138px;
}

.mob-acc .acc1-block:nth-child(4) .acc-left-block.year-head {
  right: -6px;
}

@media only screen and (device-width : 360px) and (device-height : 740px) and (orientation :portrait) {
  
  .about .yr3txt {
    right: -26px;
  }

  .mob-acc .acc1-block:nth-child(4) .acc-img-block, .mob-acc .acc1-block:nth-child(3) .acc-img-block {
    margin-right: -10px;
    left: 17px;
  }

  .acc-right-block.year-desc.yr-3-desc {
    padding-left: 22px !important;
  }

  .mob-acc .acc1-block:nth-child(5) .acc-img-block {
    left: 32px !important;
  }
}

@media only screen and (min-device-width : 360px) and (min-device-height : 649px) and (orientation :portrait) {
 /*   .circle-3 {
        top: 376px;
    }
    .circle-4 {
        top: 572px;
    }
    .circle-5 {
        top: 751px;
    }
    .circle-6 {
        top: 944px;
    }*/
  .section-1 .dosingGraphMob .dosingTitle {
    left: 55px;
  }

  .grid-container {
    margin-top: 50px;
  }
}

/*pink variable*/
/*.is-visible.numbertick .magenta-num {
    position: relative;
    display: block;
}

.is-visible.numbertick .magenta-num::before, 
.is-visible.numbertick .magenta-num::after {
    color: #FF00BA !important;
    position: absolute;
    font-size: 61px;
    top: 33px;
    font-family: system-ui !important;
    font-weight: 100 !important;
}

.is-visible.numbertick .magenta-num::before {
    content: "[";
    left: 32px;
}

.is-visible.numbertick .magenta-num::after {
    content: "]";
    right: 47px;
}

.about .is-visible.numbertick .magenta-num::before {
    content: "[";
    left: 38px;
}

.about .is-visible.numbertick .magenta-num::after {
    content: "]";
    right: 41px;
}

@media screen and (max-width: 991px) {
   .is-visible.numbertick .magenta-num::before, 
    .is-visible.numbertick .magenta-num::after {
        top: 45px;
    }
    
    .is-visible.numbertick span.magenta-num.desk-only {
        display: none!important;
    }
}*/

@media only screen and (min-width: 992px) and (max-width: 1024px) {
  .home-about .col-2, .home-about .col-1, .home-about .col-3, .home-about .col-4 {
    padding-left: 20px;
  }
}

@media only screen and (min-width: 768px) and (max-width: 1024px) {
  .about.home-about .grid-violator {
    margin: 0 auto;
    position: relative;
    text-align: center;
  }

  .about.home-about img.grid-violator-img {
    width: 293px;
    transform: none;
    margin: 0 auto;
  }
  
  .table-violator {
    /*left: 60px;*/
    /*top: 169px;*/
    left: 32px;
    top: 173px;
}

img.table-violator-img {
    width: 80px;
}

    p.footnotes-grid {
        text-align: center;
    }

  .home-about .is-visible .table-violator {
    /*transform: translate(-43%);*/
    transform: translate(-98%);
  }

  .home-about .col-2, 
    .home-about .col-1,
    .home-about .col-3,
    .home-about .col-4 {
    width: auto;
  }

  ul.nccn-tct {
    padding-right: 10px;
  }

  ul.nccn-tct li:not(:first-child)::after {
    width: 98%;
    transform: translateX(0%);
  }

  .about.home-about .circle-6 {
    left: 95%;
  }
}

@media only screen and (min-width: 992px) and (max-width: 1024px) {
    .table-violator {
        left: 351px;
        top: 9px;
    }
}

@media only screen and (min-width: 753px) and (max-width: 1037px) {
  .table-violator:after {
    left: -114px;
    top: -6px;
  }

  .grey-block.txt-ctr {
    margin: -87px 0px 0px 5px;
  }
  
  /*.circle-3 {*/
  /*      top: 426px;*/
  /*  }*/
    
  /*  .circle-4 {*/
  /*      top: 622px;*/
  /*  }*/
    
  /*  .circle-5 {*/
  /*      top: 829px;*/
  /*  }*/
    
  .circle-6 {
        /*top: 1044px;*/
    /*top: 38%;*/
            top: 39.3%;
 /*newly added (20-11-24)*/;
  }

  p.footnotes-grid {
    text-align: center;
  }

  .home-about .full-width .container {
    margin-bottom: -11px;
  }
}


@media only screen and (min-width: 990px) and (max-width: 1037px) {
    .circle-6 {
        /* top: 1044px; */
        /* top: 38%; */
        top: 37.55%;
    }
}

@media screen and (min-width: 320px) and (max-width: 350px) {
  .circle-3 {
    top: 38%;
  }

  .circle-4 {
    top: 58%;
  }

  .circle-5 {
    /*top: 75%;*/
    top: 78%;
 /*newly added (20-11-24)*/;
  }
  
  .circle-2 {
        top: 184px;
    }

  .circle-6 {
    /*top: 978px;*/
    /*top: 1100px;*/
    top: 95%;
 /*newly added (20-11-24)*/;
  }

  .line {
    /*height: 978px;*/
    /*height: 1100px;*/
        /*height: 1160px;*/
        height: 1140px;
 /*newly added (20-11-24)*/;
  }

  .grid-container .circle {
    left: 47%;
  }
  .table-violator {
        /*top: 29.4%;*/
        top: 30.7%;
    }
    
    img.table-violator-img {
        width: 87px;
    }
}

@media screen and (min-width: 320px) and (max-width: 346px) {
    .line {
        /*height: 1100px;*/
        height: 1150px;
    }
}

@media screen and (min-width: 335px) and (max-width: 351px) {
    .line {
        height: 1100px;
    }
}

@media screen and (min-width: 352px) and (max-width: 360px) {
    .table-violator {
        top: 31.5%;
    }
}

@media screen and (min-device-width: 390px) and (max-device-width: 664px) and (orientation:portrait){
    .circle-5 {
        top: 77.8%;
    }
}

@media screen and (min-device-width: 390px) and (max-device-width: 664px) and (orientation:landscape){
    .table-violator {
        /*top: 29%;*/
        top: 31%;
    }
    .grey-block.txt-ctr {
        margin: -90px 0px 0px 5px;
    }
    p.footnotes-grid {
        text-align: center;
    }
}

@media screen and (min-width: 792px) and (max-width: 820px) {
    .circle-6 {
        top: 38.3%;
    }
}

@media screen and (min-width: 821px) and (max-width: 990px) {
    .circle-6 {
        top: 38.3%;
    }
}

@media screen and (max-width: 375px) {
    .circle-2 {
        /*top: 167px;*/
        top: 163px;
    }
    
    .circle-3 {
        top: 38.3%;
    }
    .circle-4 {
        /*top: 57.5%;*/
        top: 57%;
    }
    .circle-5 {
        /*top: 77%;*/
        top: 76.5%;
    }
    .grid-container .circle-6 {
        left: 47.4%;
    }
}